-
1
-
-
84865427488
-
Mitochondria as sensors and regulators of calcium signalling
-
Rizzuto, R., De Stefani, D., Raffaello, A., Mammucari, C., Mitochondria as sensors and regulators of calcium signalling. Nat. Rev. Mol. Cell Biol. 13 (2012), 566–578, 10.1038/nrm3412.
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 566-578
-
-
Rizzuto, R.1
De Stefani, D.2
Raffaello, A.3
Mammucari, C.4
-
2
-
-
73049130730
-
Calcium uptake by rat kidney mitochondria
-
Deluca, H.F., Engstrom, G.W., Calcium uptake by rat kidney mitochondria. Proc. Natl. Acad. Sci. U. S. A. 47 (1961), 1744–1750 (http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid = 223205&tool = pmcentrez&rendertype = abstract, accessed September 12, 2015).
-
(1961)
Proc. Natl. Acad. Sci. U. S. A.
, vol.47
, pp. 1744-1750
-
-
Deluca, H.F.1
Engstrom, G.W.2
-
3
-
-
0001081063
-
Ca ion uptake by rat kidney mitochondria and its dependence on respiration and phosphorylation
-
Vasington, F.D., Murphy, J.V., Ca ion uptake by rat kidney mitochondria and its dependence on respiration and phosphorylation. J. Biol. Chem. 237 (1962), 2670–2677 http://www.ncbi.nlm.nih.gov/pubmed/13925019 (accessed August 14, 2015).
-
(1962)
J. Biol. Chem.
, vol.237
, pp. 2670-2677
-
-
Vasington, F.D.1
Murphy, J.V.2
-
4
-
-
0014202070
-
Chemiosmotic hypothesis of oxidative phosphorylation
-
Mitchell, P., Moyle, J., Chemiosmotic hypothesis of oxidative phosphorylation. Nature 213 (1967), 137–139 http://www.ncbi.nlm.nih.gov/pubmed/4291593 (accessed September 12, 2015).
-
(1967)
Nature
, vol.213
, pp. 137-139
-
-
Mitchell, P.1
Moyle, J.2
-
5
-
-
0032827410
-
Mitochondrial transport of cations: channels, exchangers, and permeability transition
-
(, accessed January 22, 2016)
-
Bernardi, P., Mitochondrial transport of cations: channels, exchangers, and permeability transition. Physiol. Rev. 79 (1999), 1127–1155 ( http://physrev.physiology.org/content/79/4/1127.short, accessed January 22, 2016).
-
(1999)
Physiol. Rev.
, vol.79
, pp. 1127-1155
-
-
Bernardi, P.1
-
7
-
-
0027340729
-
2 + close to IP3-sensitive channels that are sensed by neighboring mitochondria
-
2 + close to IP3-sensitive channels that are sensed by neighboring mitochondria. Science 262 (1993), 744–747 http://www.ncbi.nlm.nih.gov/pubmed/8235595 (accessed October 12, 2015).
-
(1993)
Science
, vol.262
, pp. 744-747
-
-
Rizzuto, R.1
Brini, M.2
Murgia, M.3
Pozzan, T.4
-
8
-
-
77950888855
-
2 + channels
-
2 + channels. Mol. Cell 38 (2010), 280–290, 10.1016/j.molcel.2010.04.003.
-
(2010)
Mol. Cell
, vol.38
, pp. 280-290
-
-
Giacomello, M.1
Drago, I.2
Bortolozzi, M.3
Scorzeto, M.4
Gianelle, A.5
Pizzo, P.6
-
9
-
-
77954301751
-
Imaging interorganelle contacts and local calcium dynamics at the ER-mitochondrial interface
-
Csordás, G., Várnai, P., Golenár, T., Roy, S., Purkins, G., Schneider, T.G., et al. Imaging interorganelle contacts and local calcium dynamics at the ER-mitochondrial interface. Mol. Cell 39 (2010), 121–132, 10.1016/j.molcel.2010.06.029.
-
(2010)
Mol. Cell
, vol.39
, pp. 121-132
-
-
Csordás, G.1
Várnai, P.2
Golenár, T.3
Roy, S.4
Purkins, G.5
Schneider, T.G.6
-
10
-
-
0019025638
-
The role of calcium in the regulation of mitochondrial metabolism
-
Denton, R.M., McCormack, J.G., The role of calcium in the regulation of mitochondrial metabolism. Biochem. Soc. Trans. 8 (1980), 266–268, 10.1042/bst0080266.
-
(1980)
Biochem. Soc. Trans.
, vol.8
, pp. 266-268
-
-
Denton, R.M.1
McCormack, J.G.2
-
11
-
-
0034668833
-
Mitochondria and calcium: from cell signalling to cell death
-
Duchen, M.R., Mitochondria and calcium: from cell signalling to cell death. J. Physiol. 529 (2000), 57–68, 10.1111/j.1469-7793.2000.00057.x.
-
(2000)
J. Physiol.
, vol.529
, pp. 57-68
-
-
Duchen, M.R.1
-
12
-
-
1642540210
-
The mitochondrial calcium uniporter is a highly selective ion channel
-
Kirichok, Y., Krapivinsky, G., Clapham, D.E., The mitochondrial calcium uniporter is a highly selective ion channel. Nature 427 (2004), 360–364, 10.1038/nature02246.
-
(2004)
Nature
, vol.427
, pp. 360-364
-
-
Kirichok, Y.1
Krapivinsky, G.2
Clapham, D.E.3
-
13
-
-
80051936634
-
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
-
De Stefani, D., Raffaello, A., Teardo, E., Szabò, I., Rizzuto, R., A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter. Nature 476 (2011), 336–340, 10.1038/nature10230.
-
(2011)
Nature
, vol.476
, pp. 336-340
-
-
De Stefani, D.1
Raffaello, A.2
Teardo, E.3
Szabò, I.4
Rizzuto, R.5
-
14
-
-
80051946060
-
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
-
Baughman, J.M., Perocchi, F., Girgis, H.S., Plovanich, M., Belcher-Timme, C.A., Sancak, Y., et al. Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter. Nature 476 (2011), 341–345, 10.1038/nature10234.
-
(2011)
Nature
, vol.476
, pp. 341-345
-
-
Baughman, J.M.1
Perocchi, F.2
Girgis, H.S.3
Plovanich, M.4
Belcher-Timme, C.A.5
Sancak, Y.6
-
15
-
-
84952631027
-
Structure and function of the mitochondrial calcium uniporter complex
-
De Stefani, D., Patron, M., Rizzuto, R., Structure and function of the mitochondrial calcium uniporter complex. Biochim. Biophys. Acta 1853 (2015), 2006–2011, 10.1016/j.bbamcr.2015.04.008.
-
(2015)
Biochim. Biophys. Acta
, vol.1853
, pp. 2006-2011
-
-
De Stefani, D.1
Patron, M.2
Rizzuto, R.3
-
16
-
-
84891393224
-
The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter
-
Pan, X., Liu, J., Nguyen, T., Liu, C., Sun, J., Teng, Y., et al. The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter. Nat. Cell Biol. 15 (2013), 1464–1472, 10.1038/ncb2868.
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 1464-1472
-
-
Pan, X.1
Liu, J.2
Nguyen, T.3
Liu, C.4
Sun, J.5
Teng, Y.6
-
18
-
-
84868629814
-
CaMKII determines mitochondrial stress responses in heart
-
Joiner, M.-L.A., Koval, O.M., Li, J., He, B.J., Allamargot, C., Gao, Z., et al. CaMKII determines mitochondrial stress responses in heart. Nature 491 (2012), 269–273, 10.1038/nature11444.
-
(2012)
Nature
, vol.491
, pp. 269-273
-
-
Joiner, M.-L.A.1
Koval, O.M.2
Li, J.3
He, B.J.4
Allamargot, C.5
Gao, Z.6
-
19
-
-
84864070892
-
2 + uniporter MCU Is essential for glucose-induced ATP increases in pancreatic β-cells
-
e39722
-
2 + uniporter MCU Is essential for glucose-induced ATP increases in pancreatic β-cells. PLoS One, 7, 2012, e39722, 10.1371/journal.pone.0039722.
-
(2012)
PLoS One
, vol.7
-
-
Tarasov, A.I.1
Semplici, F.2
Ravier, M.A.3
Bellomo, E.A.4
Pullen, T.J.5
Gilon, P.6
-
20
-
-
84879627185
-
Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals
-
Qiu, J., Tan, Y.-W., Hagenston, A.M., Martel, M.-A., Kneisel, N., Skehel, P.A., et al. Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals. Nat. Commun., 4, 2013, 2034, 10.1038/ncomms3034.
-
(2013)
Nat. Commun.
, vol.4
, pp. 2034
-
-
Qiu, J.1
Tan, Y.-W.2
Hagenston, A.M.3
Martel, M.-A.4
Kneisel, N.5
Skehel, P.A.6
-
21
-
-
84883286784
-
The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit
-
Raffaello, A., De Stefani, D., Sabbadin, D., Teardo, E., Merli, G., Picard, A., et al. The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit. EMBO J. 32 (2013), 2362–2376, 10.1038/emboj.2013.157.
-
(2013)
EMBO J.
, vol.32
, pp. 2362-2376
-
-
Raffaello, A.1
De Stefani, D.2
Sabbadin, D.3
Teardo, E.4
Merli, G.5
Picard, A.6
-
22
-
-
84890116192
-
EMRE is an essential component of the mitochondrial calcium uniporter complex
-
Sancak, Y., Markhard, A.L.L., Kitami, T., Kovacs-Bogdan, E., Kamer, K.J.J., Udeshi, N.D.D., et al. EMRE is an essential component of the mitochondrial calcium uniporter complex. Science 342 (2013), 1379–1382, 10.1126/science.1242993.
-
(2013)
Science
, vol.342
, pp. 1379-1382
-
-
Sancak, Y.1
Markhard, A.L.L.2
Kitami, T.3
Kovacs-Bogdan, E.4
Kamer, K.J.J.5
Udeshi, N.D.D.6
-
23
-
-
84871891066
-
Activity of the mitochondrial calcium uniporter varies greatly between tissues
-
Fieni, F., Lee, S.B., Jan, Y.N., Kirichok, Y., Activity of the mitochondrial calcium uniporter varies greatly between tissues. Nat. Commun., 3, 2012, 1317, 10.1038/ncomms2325.
-
(2012)
Nat. Commun.
, vol.3
, pp. 1317
-
-
Fieni, F.1
Lee, S.B.2
Jan, Y.N.3
Kirichok, Y.4
-
24
-
-
84896703008
-
2 + uniporter by exerting opposite effects on MCU activity
-
2 + uniporter by exerting opposite effects on MCU activity. Mol. Cell 53 (2014), 726–737, 10.1016/j.molcel.2014.01.013.
-
(2014)
Mol. Cell
, vol.53
, pp. 726-737
-
-
Patron, M.1
Checchetto, V.2
Raffaello, A.3
Teardo, E.4
Vecellio Reane, D.5
Mantoan, M.6
-
25
-
-
84902579068
-
Reconstitution of the mitochondrial calcium uniporter in yeast
-
Kovács-Bogdán, E., Sancak, Y., Kamer, K.J.J., Plovanich, M., Jambhekar, A., Huber, R.J.J., et al. Reconstitution of the mitochondrial calcium uniporter in yeast. Proc. Natl. Acad. Sci. U. S. A. 111 (2014), 8985–8990, 10.1073/pnas.1400514111.
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. 8985-8990
-
-
Kovács-Bogdán, E.1
Sancak, Y.2
Kamer, K.J.J.3
Plovanich, M.4
Jambhekar, A.5
Huber, R.J.J.6
-
26
-
-
84953438754
-
EMRE Is a matrix Ca(2 +) sensor that governs gatekeeping of the mitochondrial Ca(2 +) uniporter
-
Vais, H., Mallilankaraman, K., Mak, D.-O.D., Hoff, H., Payne, R., Tanis, J.E., et al. EMRE Is a matrix Ca(2 +) sensor that governs gatekeeping of the mitochondrial Ca(2 +) uniporter. Cell Rep., 2016, 10.1016/j.celrep.2015.12.054.
-
(2016)
Cell Rep.
-
-
Vais, H.1
Mallilankaraman, K.2
Mak, D.-O.D.3
Hoff, H.4
Payne, R.5
Tanis, J.E.6
-
27
-
-
0033521586
-
Quasi-synaptic calcium signal transmission between endoplasmic reticulum and mitochondria
-
Csordás, G., Thomas, A.P., Hajnóczky, G., Quasi-synaptic calcium signal transmission between endoplasmic reticulum and mitochondria. EMBO J. 18 (1999), 96–108, 10.1093/emboj/18.1.96.
-
(1999)
EMBO J.
, vol.18
, pp. 96-108
-
-
Csordás, G.1
Thomas, A.P.2
Hajnóczky, G.3
-
28
-
-
0032511112
-
2 + responses
-
2 + responses. Science 280 (1998), 1763–1766, 10.1126/science.280.5370.1763.
-
(1998)
Science
, vol.280
, pp. 1763-1766
-
-
Rizzuto, R.1
Pinton, P.2
Carrington, W.3
Fay, F.S.4
Fogarty, K.E.5
Lifshitz, L.M.6
-
29
-
-
84869458315
-
Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy
-
Martell, J.D., Deerinck, T.J., Sancak, Y., Poulos, T.L., Mootha, V.K., Sosinsky, G.E., et al. Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy. Nat. Biotechnol. 30 (2012), 1143–1148, 10.1038/nbt.2375.
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 1143-1148
-
-
Martell, J.D.1
Deerinck, T.J.2
Sancak, Y.3
Poulos, T.L.4
Mootha, V.K.5
Sosinsky, G.E.6
-
30
-
-
84940438466
-
The molecular era of the mitochondrial calcium uniporter
-
Kamer, K.J., Mootha, V.K., The molecular era of the mitochondrial calcium uniporter. Nat. Rev. Mol. Cell Biol. 16 (2015), 545–553, 10.1038/nrm4039.
-
(2015)
Nat. Rev. Mol. Cell Biol.
, vol.16
, pp. 545-553
-
-
Kamer, K.J.1
Mootha, V.K.2
-
31
-
-
77956928316
-
MICU1 encodes a mitochondrial EF hand protein required for Ca(2 +) uptake
-
Perocchi, F., Gohil, V.M., Girgis, H.S., Bao, X.R., McCombs, J.E., Palmer, A.E., et al. MICU1 encodes a mitochondrial EF hand protein required for Ca(2 +) uptake. Nature 467 (2010), 291–296, 10.1038/nature09358.
-
(2010)
Nature
, vol.467
, pp. 291-296
-
-
Perocchi, F.1
Gohil, V.M.2
Girgis, H.S.3
Bao, X.R.4
McCombs, J.E.5
Palmer, A.E.6
-
32
-
-
46349103594
-
A mitochondrial protein compendium elucidates complex I disease biology
-
Pagliarini, D.J., Calvo, S.E., Chang, B., Sheth, S.A., Vafai, S.B., Ong, S.-E., et al. A mitochondrial protein compendium elucidates complex I disease biology. Cell 134 (2008), 112–123, 10.1016/j.cell.2008.06.016.
-
(2008)
Cell
, vol.134
, pp. 112-123
-
-
Pagliarini, D.J.1
Calvo, S.E.2
Chang, B.3
Sheth, S.A.4
Vafai, S.B.5
Ong, S.-E.6
-
33
-
-
84868027665
-
MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2 +) uptake that regulates cell survival
-
Mallilankaraman, K., Doonan, P., Cárdenas, C., Chandramoorthy, H.C., Müller, M., Miller, R., et al. MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2 +) uptake that regulates cell survival. Cell 151 (2012), 630–644, 10.1016/j.cell.2012.10.011.
-
(2012)
Cell
, vol.151
, pp. 630-644
-
-
Mallilankaraman, K.1
Doonan, P.2
Cárdenas, C.3
Chandramoorthy, H.C.4
Müller, M.5
Miller, R.6
-
34
-
-
84891011448
-
MICU1 motifs define mitochondrial calcium uniporter binding and activity
-
Hoffman, N.E., Chandramoorthy, H.C., Shamugapriya, S., Zhang, X., Rajan, S., Mallilankaraman, K., et al. MICU1 motifs define mitochondrial calcium uniporter binding and activity. Cell Rep. 5 (2013), 1576–1588, 10.1016/j.celrep.2013.11.026.
-
(2013)
Cell Rep.
, vol.5
, pp. 1576-1588
-
-
Hoffman, N.E.1
Chandramoorthy, H.C.2
Shamugapriya, S.3
Zhang, X.4
Rajan, S.5
Mallilankaraman, K.6
-
35
-
-
84878796986
-
2 + uniporter
-
2 + uniporter. Cell Metab. 17 (2013), 976–987, 10.1016/j.cmet.2013.04.020.
-
(2013)
Cell Metab.
, vol.17
, pp. 976-987
-
-
Csordás, G.1
Golenár, T.2
Seifert, E.L.3
Kamer, K.J.4
Sancak, Y.5
Perocchi, F.6
-
36
-
-
84926166583
-
Directed evolution of APEX2 for electron microscopy and proximity labeling
-
Lam, S.S., Martell, J.D., Kamer, K.J., Deerinck, T.J., Ellisman, M.H., Mootha, V.K., et al. Directed evolution of APEX2 for electron microscopy and proximity labeling. Nat. Methods 12 (2014), 51–54, 10.1038/nmeth.3179.
-
(2014)
Nat. Methods
, vol.12
, pp. 51-54
-
-
Lam, S.S.1
Martell, J.D.2
Kamer, K.J.3
Deerinck, T.J.4
Ellisman, M.H.5
Mootha, V.K.6
-
37
-
-
84907772320
-
Proteomic mapping of the human mitochondrial intermembrane space in live cells via ratiometric APEX tagging
-
Hung, V., Zou, P., Rhee, H.-W., Udeshi, N.D., Cracan, V., Svinkina, T., et al. Proteomic mapping of the human mitochondrial intermembrane space in live cells via ratiometric APEX tagging. Mol. Cell 55 (2014), 332–341, 10.1016/j.molcel.2014.06.003.
-
(2014)
Mol. Cell
, vol.55
, pp. 332-341
-
-
Hung, V.1
Zou, P.2
Rhee, H.-W.3
Udeshi, N.D.4
Cracan, V.5
Svinkina, T.6
-
38
-
-
84890116192
-
EMRE is an essential component of the mitochondrial calcium uniporter complex
-
Sancak, Y., Markhard, A.L., Kitami, T., Kovacs-Bogdan, E., Kamer, K.J., Udeshi, N.D., et al. EMRE is an essential component of the mitochondrial calcium uniporter complex. Science 30:80-. (2013), 1143–1148, 10.1126/science.1242993.
-
(2013)
Science
, vol.30
, Issue.80
, pp. 1143-1148
-
-
Sancak, Y.1
Markhard, A.L.2
Kitami, T.3
Kovacs-Bogdan, E.4
Kamer, K.J.5
Udeshi, N.D.6
-
39
-
-
84895426147
-
Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling
-
Logan, C.V., Szabadkai, G., Sharpe, J.A., Parry, D.A., Torelli, S., Childs, A.-M., et al. Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling. Nat. Genet. 46 (2014), 188–193, 10.1038/ng.2851.
-
(2014)
Nat. Genet.
, vol.46
, pp. 188-193
-
-
Logan, C.V.1
Szabadkai, G.2
Sharpe, J.A.3
Parry, D.A.4
Torelli, S.5
Childs, A.-M.6
-
40
-
-
84873572862
-
MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling
-
e55785
-
Plovanich, M., Bogorad, R.L., Sancak, Y., Kamer, K.J., Strittmatter, L., Li, A.A., et al. MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling. PLoS One, 8, 2013, e55785, 10.1371/journal.pone.0055785.
-
(2013)
PLoS One
, vol.8
-
-
Plovanich, M.1
Bogorad, R.L.2
Sancak, Y.3
Kamer, K.J.4
Strittmatter, L.5
Li, A.A.6
-
41
-
-
84898644111
-
MICU1 and MICU2 play nonredundant roles in the regulation of the mitochondrial calcium uniporter
-
Kamer, K.J., Mootha, V.K., MICU1 and MICU2 play nonredundant roles in the regulation of the mitochondrial calcium uniporter. EMBO Rep. 15 (2014), 299–307, 10.1002/embr.201337946.
-
(2014)
EMBO Rep.
, vol.15
, pp. 299-307
-
-
Kamer, K.J.1
Mootha, V.K.2
-
42
-
-
84870621600
-
2 + uptake that regulates cellular metabolism
-
2 + uptake that regulates cellular metabolism. Nat. Cell Biol. 14 (2012), 1336–1343, 10.1038/ncb2622.
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 1336-1343
-
-
Mallilankaraman, K.1
Cárdenas, C.2
Doonan, P.J.3
Chandramoorthy, H.C.4
Irrinki, K.M.5
Golenár, T.6
-
43
-
-
84920617467
-
CCDC90A (MCUR1) is a cytochrome c oxidase assembly factor and not a regulator of the mitochondrial calcium uniporter
-
Paupe, V., Prudent, J., Dassa, E.P., Rendon, O.Z., Shoubridge, E.A., CCDC90A (MCUR1) is a cytochrome c oxidase assembly factor and not a regulator of the mitochondrial calcium uniporter. Cell Metab. 21 (2015), 109–116, 10.1016/j.cmet.2014.12.004.
-
(2015)
Cell Metab.
, vol.21
, pp. 109-116
-
-
Paupe, V.1
Prudent, J.2
Dassa, E.P.3
Rendon, O.Z.4
Shoubridge, E.A.5
-
44
-
-
84943383907
-
MCUR1, CCDC90A, is a regulator of the mitochondrial calcium uniporter
-
Vais, H., Tanis, J.E., Müller, M., Payne, R., Mallilankaraman, K., Foskett, J.K., MCUR1, CCDC90A, is a regulator of the mitochondrial calcium uniporter. Cell Metab. 22 (2015), 533–535, 10.1016/j.cmet.2015.09.015.
-
(2015)
Cell Metab.
, vol.22
, pp. 533-535
-
-
Vais, H.1
Tanis, J.E.2
Müller, M.3
Payne, R.4
Mallilankaraman, K.5
Foskett, J.K.6
-
45
-
-
84877821673
-
Frequency-dependent mitochondrial Ca(2 +) accumulation regulates ATP synthesis in pancreatic β cells
-
Tarasov, A.I., Semplici, F., Li, D., Rizzuto, R., Ravier, M.A., Gilon, P., et al. Frequency-dependent mitochondrial Ca(2 +) accumulation regulates ATP synthesis in pancreatic β cells. Pflugers Arch. 465 (2013), 543–554, 10.1007/s00424-012-1177-9.
-
(2013)
Pflugers Arch.
, vol.465
, pp. 543-554
-
-
Tarasov, A.I.1
Semplici, F.2
Li, D.3
Rizzuto, R.4
Ravier, M.A.5
Gilon, P.6
-
46
-
-
84867272349
-
2 + uniporter (MCU) contribute to metabolism-secretion coupling in clonal pancreatic β-cells
-
2 + uniporter (MCU) contribute to metabolism-secretion coupling in clonal pancreatic β-cells. J. Biol. Chem. 287 (2012), 34445–34454, 10.1074/jbc.M112.392084.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 34445-34454
-
-
Alam, M.R.1
Groschner, L.N.2
Parichatikanond, W.3
Kuo, L.4
Bondarenko, A.I.5
Rost, R.6
-
47
-
-
64149126546
-
Regulation of insulin secretion: a matter of phase control and amplitude modulation
-
Henquin, J.C., Regulation of insulin secretion: a matter of phase control and amplitude modulation. Diabetologia 52 (2009), 739–751, 10.1007/s00125-009-1314-y.
-
(2009)
Diabetologia
, vol.52
, pp. 739-751
-
-
Henquin, J.C.1
-
48
-
-
79955576907
-
Mitochondrial matrix calcium is an activating signal for hormone secretion
-
Wiederkehr, A., Szanda, G., Akhmedov, D., Mataki, C., Heizmann, C.W., Schoonjans, K., et al. Mitochondrial matrix calcium is an activating signal for hormone secretion. Cell Metab. 13 (2011), 601–611, 10.1016/j.cmet.2011.03.015.
-
(2011)
Cell Metab.
, vol.13
, pp. 601-611
-
-
Wiederkehr, A.1
Szanda, G.2
Akhmedov, D.3
Mataki, C.4
Heizmann, C.W.5
Schoonjans, K.6
-
49
-
-
84922949995
-
2 + uniporter in the generation of mitochondrial pH gradient and metabolism-secretion coupling in insulin-releasing cells
-
2 + uniporter in the generation of mitochondrial pH gradient and metabolism-secretion coupling in insulin-releasing cells. J. Biol. Chem. 290 (2015), 4086–4096, 10.1074/jbc.M114.632547.
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 4086-4096
-
-
Quan, X.1
Nguyen, T.T.2
Choi, S.-K.3
Xu, S.4
Das, R.5
Cha, S.-K.6
-
50
-
-
84912127169
-
Calcium signaling in pancreatic β-cells in health and in type 2 diabetes
-
Gilon, P., Chae, H.-Y., Rutter, G.A., Ravier, M.A., Calcium signaling in pancreatic β-cells in health and in type 2 diabetes. Cell Calcium 56 (2014), 340–361, 10.1016/j.ceca.2014.09.001.
-
(2014)
Cell Calcium
, vol.56
, pp. 340-361
-
-
Gilon, P.1
Chae, H.-Y.2
Rutter, G.A.3
Ravier, M.A.4
-
51
-
-
84872117185
-
Downregulation of the mitochondrial calcium uniporter by cancer-related miR-25
-
Marchi, S., Lupini, L., Patergnani, S., Rimessi, A., Missiroli, S., Bonora, M., et al. Downregulation of the mitochondrial calcium uniporter by cancer-related miR-25. Curr. Biol. 23 (2013), 58–63, 10.1016/j.cub.2012.11.026.
-
(2013)
Curr. Biol.
, vol.23
, pp. 58-63
-
-
Marchi, S.1
Lupini, L.2
Patergnani, S.3
Rimessi, A.4
Missiroli, S.5
Bonora, M.6
-
52
-
-
84880471564
-
Mitochondrial calcium uniporter silencing potentiates caspase-independent cell death in MDA-MB-231 breast cancer cells
-
Curry, M.C., Peters, A.A., Kenny, P.A., Roberts-Thomson, S.J., Monteith, G.R., Mitochondrial calcium uniporter silencing potentiates caspase-independent cell death in MDA-MB-231 breast cancer cells. Biochem. Biophys. Res. Commun. 434 (2013), 695–700, 10.1016/j.bbrc.2013.04.015.
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.434
, pp. 695-700
-
-
Curry, M.C.1
Peters, A.A.2
Kenny, P.A.3
Roberts-Thomson, S.J.4
Monteith, G.R.5
-
53
-
-
84900451895
-
Mitochondrial calcium uniporter activity is dispensable for MDA-MB-231 breast carcinoma cell survival
-
e96866
-
Hall, D.D., Wu, Y., Domann, F.E., Spitz, D.R., Anderson, M.E., Mitochondrial calcium uniporter activity is dispensable for MDA-MB-231 breast carcinoma cell survival. PLoS One, 9, 2014, e96866, 10.1371/journal.pone.0096866.
-
(2014)
PLoS One
, vol.9
-
-
Hall, D.D.1
Wu, Y.2
Domann, F.E.3
Spitz, D.R.4
Anderson, M.E.5
-
54
-
-
84923226856
-
2 + entry-dependent breast cancer cell migration
-
2 + entry-dependent breast cancer cell migration. Biochem. Biophys. Res. Commun. 458 (2015), 186–193, 10.1016/j.bbrc.2015.01.092.
-
(2015)
Biochem. Biophys. Res. Commun.
, vol.458
, pp. 186-193
-
-
Tang, S.1
Wang, X.2
Shen, Q.3
Yang, X.4
Yu, C.5
Cai, C.6
-
55
-
-
84963644294
-
The mitochondrial calcium uniporter regulates breast cancer progression via HIF-1α
-
Tosatto, A., Sommaggio, R., Kummerow, C., Bentham, R.R., Blacker, T.S., Berecz, T., Duchen, M.R., Rosato, A., Bogeski, I., Szabadkai, G., Rizzuto, R., Mammucari, C., The mitochondrial calcium uniporter regulates breast cancer progression via HIF-1α. EMBO Mol. Med., 2016.
-
(2016)
EMBO Mol. Med.
-
-
Tosatto, A.1
Sommaggio, R.2
Kummerow, C.3
Bentham, R.R.4
Blacker, T.S.5
Berecz, T.6
Duchen, M.R.7
Rosato, A.8
Bogeski, I.9
Szabadkai, G.10
Rizzuto, R.11
Mammucari, C.12
-
56
-
-
84971221416
-
Excitotoxicity and stroke: identifying novel targets for neuroprotection
-
Lai, T.W., Zhang, S., Wang, Y.T., Excitotoxicity and stroke: identifying novel targets for neuroprotection. Prog. Neurobiol. 115 (2014), 157–188, 10.1016/j.pneurobio.2013.11.006.
-
(2014)
Prog. Neurobiol.
, vol.115
, pp. 157-188
-
-
Lai, T.W.1
Zhang, S.2
Wang, Y.T.3
-
57
-
-
84916600936
-
Mitochondrial calcium and the regulation of metabolism in the heart
-
Williams, G.S.B., Boyman, L., Lederer, W.J., Mitochondrial calcium and the regulation of metabolism in the heart. J. Mol. Cell. Cardiol. 78 (2015), 35–45, 10.1016/j.yjmcc.2014.10.019.
-
(2015)
J. Mol. Cell. Cardiol.
, vol.78
, pp. 35-45
-
-
Williams, G.S.B.1
Boyman, L.2
Lederer, W.J.3
-
59
-
-
84931273624
-
Assessment of cardiac function in mice lacking the mitochondrial calcium uniporter
-
Holmström, K.M., Pan, X., Liu, J.C.J.C., Menazza, S., Liu, J.C.J.C., Nguyen, T.T., et al. Assessment of cardiac function in mice lacking the mitochondrial calcium uniporter. J. Mol. Cell. Cardiol. 85 (2015), 178–182, 10.1016/j.yjmcc.2015.05.022.
-
(2015)
J. Mol. Cell. Cardiol.
, vol.85
, pp. 178-182
-
-
Holmström, K.M.1
Pan, X.2
Liu, J.C.J.C.3
Menazza, S.4
Liu, J.C.J.C.5
Nguyen, T.T.6
-
60
-
-
84902883454
-
Unresolved questions from the analysis of mice lacking MCU expression
-
Murphy, E., Pan, X., Nguyen, T., Liu, J., Holmström, K.M., Finkel, T., Unresolved questions from the analysis of mice lacking MCU expression. Biochem. Biophys. Res. Commun. 449 (2014), 384–385, 10.1016/j.bbrc.2014.04.144.
-
(2014)
Biochem. Biophys. Res. Commun.
, vol.449
, pp. 384-385
-
-
Murphy, E.1
Pan, X.2
Nguyen, T.3
Liu, J.4
Holmström, K.M.5
Finkel, T.6
-
61
-
-
84930394045
-
The mitochondrial uniporter controls fight or flight heart rate increases
-
Wu, Y., Rasmussen, T.P., Koval, O.M., Joiner, M.-L.A., Hall, D.D., Chen, B., et al. The mitochondrial uniporter controls fight or flight heart rate increases. Nat. Commun., 6, 2015, 6081, 10.1038/ncomms7081.
-
(2015)
Nat. Commun.
, vol.6
, pp. 6081
-
-
Wu, Y.1
Rasmussen, T.P.2
Koval, O.M.3
Joiner, M.-L.A.4
Hall, D.D.5
Chen, B.6
-
62
-
-
84937689030
-
Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart
-
Rasmussen, T.P., Wu, Y., Joiner, M.A., Koval, O.M., Wilson, N.R., Luczak, E.D., et al. Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart. Proc. Natl. Acad. Sci. U. S. A. 112 (2015), 9129–9134, 10.1073/pnas.1504705112.
-
(2015)
Proc. Natl. Acad. Sci. U. S. A.
, vol.112
, pp. 9129-9134
-
-
Rasmussen, T.P.1
Wu, Y.2
Joiner, M.A.3
Koval, O.M.4
Wilson, N.R.5
Luczak, E.D.6
-
63
-
-
84937525656
-
The mitochondrial calcium uniporter matches energetic supply with cardiac workload during stress and modulates permeability transition
-
Luongo, T.S., Lambert, J.P., Yuan, A., Zhang, X., Gross, P., Song, J., et al. The mitochondrial calcium uniporter matches energetic supply with cardiac workload during stress and modulates permeability transition. Cell Rep. 12 (2015), 23–34, 10.1016/j.celrep.2015.06.017.
-
(2015)
Cell Rep.
, vol.12
, pp. 23-34
-
-
Luongo, T.S.1
Lambert, J.P.2
Yuan, A.3
Zhang, X.4
Gross, P.5
Song, J.6
-
64
-
-
84937515068
-
The mitochondrial calcium uniporter selectively matches metabolic output to acute contractile stress in the heart
-
Kwong, J.Q.Q.Q., Lu, X., Correll, R.N.N.N., Schwanekamp, J.A.A.a., Vagnozzi, R.J.J.J., Sargent, M.A.A.a., et al. The mitochondrial calcium uniporter selectively matches metabolic output to acute contractile stress in the heart. Cell Rep. 12 (2015), 15–22, 10.1016/j.celrep.2015.06.002.
-
(2015)
Cell Rep.
, vol.12
, pp. 15-22
-
-
Kwong, J.Q.Q.Q.1
Lu, X.2
Correll, R.N.N.N.3
Schwanekamp, J.A.A.A.4
Vagnozzi, R.J.J.J.5
Sargent, M.A.A.A.6
-
66
-
-
84904977395
-
2 + uniporter
-
2 + uniporter. Antioxid. Redox Signal. 21 (2014), 863–879, 10.1089/ars.2013.5394.
-
(2014)
Antioxid. Redox Signal.
, vol.21
, pp. 863-879
-
-
O-Uchi, J.1
Jhun, B.S.2
Xu, S.3
Hurst, S.4
Raffaello, A.5
Liu, X.6
-
67
-
-
84925857762
-
MiR-25 protects cardiomyocytes against oxidative damage by targeting the mitochondrial calcium uniporter
-
Pan, L., Huang, B.-J., Ma, X.-E., Wang, S.-Y., Feng, J., Lv, F., et al. MiR-25 protects cardiomyocytes against oxidative damage by targeting the mitochondrial calcium uniporter. Int. J. Mol. Sci. 16 (2015), 5420–5433, 10.3390/ijms16035420.
-
(2015)
Int. J. Mol. Sci.
, vol.16
, pp. 5420-5433
-
-
Pan, L.1
Huang, B.-J.2
Ma, X.-E.3
Wang, S.-Y.4
Feng, J.5
Lv, F.6
-
68
-
-
84924613885
-
The mitochondrial calcium uniporter controls skeletal muscle trophism in vivo
-
Mammucari, C., Gherardi, G., Zamparo, I., Raffaello, A., Boncompagni, S., Chemello, F., et al. The mitochondrial calcium uniporter controls skeletal muscle trophism in vivo. Cell Rep. 10 (2015), 1269–1279, 10.1016/j.celrep.2015.01.056.
-
(2015)
Cell Rep.
, vol.10
, pp. 1269-1279
-
-
Mammucari, C.1
Gherardi, G.2
Zamparo, I.3
Raffaello, A.4
Boncompagni, S.5
Chemello, F.6
-
69
-
-
84930677253
-
Gene expression changes of single skeletal muscle fibers in response to modulation of the mitochondrial calcium uniporter (MCU)
-
Chemello, F., Mammucari, C., Gherardi, G., Rizzuto, R., Lanfranchi, G., Cagnin, S., Gene expression changes of single skeletal muscle fibers in response to modulation of the mitochondrial calcium uniporter (MCU). Genomics Data 5 (2015), 64–67, 10.1016/j.gdata.2015.05.023.
-
(2015)
Genomics Data
, vol.5
, pp. 64-67
-
-
Chemello, F.1
Mammucari, C.2
Gherardi, G.3
Rizzuto, R.4
Lanfranchi, G.5
Cagnin, S.6
-
70
-
-
77956928316
-
2 + uptake
-
2 + uptake. Nature 467 (2010), 291–296, 10.1038/nature09358.
-
(2010)
Nature
, vol.467
, pp. 291-296
-
-
Perocchi, F.1
Gohil, V.M.2
Girgis, H.S.3
Bao, X.R.4
McCombs, J.E.5
Palmer, A.E.6
|