메뉴 건너뛰기




Volumn 67, Issue 10, 2016, Pages 1214-1226

Long Noncoding RNAs from Clinical Genetics to Therapeutic Targets?

Author keywords

Key Words cardiac; long noncoding RNA; microRNA; vascular

Indexed keywords

BIOLOGICAL MARKER; LONG UNTRANSLATED RNA; RNA;

EID: 84961221422     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2015.12.051     Document Type: Review
Times cited : (414)

References (114)
  • 1
    • 0000822856 scopus 로고
    • The genetic organization of chromosomes
    • C.A. Thomas Jr. The genetic organization of chromosomes Annu Rev Genet 5 1971 237 256
    • (1971) Annu Rev Genet , vol.5 , pp. 237-256
    • Thomas, C.A.1
  • 2
    • 0015271630 scopus 로고
    • So much "junk" DNA in our genome
    • S. Ohno So much "junk" DNA in our genome Brookhaven Symp Biol 23 1972 366 370
    • (1972) Brookhaven Symp Biol , vol.23 , pp. 366-370
    • Ohno, S.1
  • 3
    • 0016826992 scopus 로고
    • Sequence complexity of heterogeneous nuclear RNA in sea urchin embryos
    • B.R. Hough, M.J. Smith, R.J. Britten, and et al. Sequence complexity of heterogeneous nuclear RNA in sea urchin embryos Cell 5 1975 291 299
    • (1975) Cell , vol.5 , pp. 291-299
    • Hough, B.R.1    Smith, M.J.2    Britten, R.J.3
  • 4
    • 0017688583 scopus 로고
    • An amazing sequence arrangement at the 5′ ends of adenovirus 2 messenger RNA
    • L.T. Chow, R.E. Gelinas, T.R. Broker, and et al. An amazing sequence arrangement at the 5′ ends of adenovirus 2 messenger RNA Cell 12 1977 1 8
    • (1977) Cell , vol.12 , pp. 1-8
    • Chow, L.T.1    Gelinas, R.E.2    Broker, T.R.3
  • 5
    • 0344622123 scopus 로고
    • Spliced segments at the 5′ terminus of adenovirus 2 late mRNA
    • S.M. Berget, C. Moore, and P.A. Sharp Spliced segments at the 5′ terminus of adenovirus 2 late mRNA Proc Natl Acad Sci USA 74 1977 3171 3175
    • (1977) Proc Natl Acad Sci USA , vol.74 , pp. 3171-3175
    • Berget, S.M.1    Moore, C.2    Sharp, P.A.3
  • 6
    • 0017855369 scopus 로고
    • Ribonuclease P: An enzyme with an essential RNA component
    • B.C. Stark, R. Kole, E.J. Bowman, and et al. Ribonuclease P: An enzyme with an essential RNA component Proc Natl Acad Sci USA 75 1978 3717 3721
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 3717-3721
    • Stark, B.C.1    Kole, R.2    Bowman, E.J.3
  • 7
    • 0000341684 scopus 로고
    • Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus
    • M.R. Lerner, and J.A. Steitz Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus Proc Natl Acad Sci USA 76 1979 5495 5499
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 5495-5499
    • Lerner, M.R.1    Steitz, J.A.2
  • 8
    • 0025961771 scopus 로고
    • A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome
    • C.J. Brown, A. Ballabio, J.L. Rupert, and et al. A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome Nature 349 1991 38 44
    • (1991) Nature , vol.349 , pp. 38-44
    • Brown, C.J.1    Ballabio, A.2    Rupert, J.L.3
  • 9
    • 0025809321 scopus 로고
    • Parental imprinting of the mouse H19 gene
    • M.S. Bartolomei, S. Zemel, and S.M. Tilghman Parental imprinting of the mouse H19 gene Nature 351 1991 153 155
    • (1991) Nature , vol.351 , pp. 153-155
    • Bartolomei, M.S.1    Zemel, S.2    Tilghman, S.M.3
  • 10
    • 0027751663 scopus 로고
    • The C. Elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • R.C. Lee, R.L. Feinbaum, and V. Ambros The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14 Cell 75 1993 843 854
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 11
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: Small RNAs with a big role in gene regulation
    • L. He, and G.J. Hannon MicroRNAs: Small RNAs with a big role in gene regulation Nat Rev Genet 5 2004 522 531
    • (2004) Nat Rev Genet , vol.5 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 12
    • 56649117675 scopus 로고    scopus 로고
    • The assembly of a spliceosomal small nuclear ribonucleoprotein particle
    • S.B. Patel, and M. Bellini The assembly of a spliceosomal small nuclear ribonucleoprotein particle Nucleic Acids Res 36 2008 6482 6493
    • (2008) Nucleic Acids Res , vol.36 , pp. 6482-6493
    • Patel, S.B.1    Bellini, M.2
  • 13
    • 34250305146 scopus 로고    scopus 로고
    • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
    • ENCODE Project Consortium Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project Nature 447 2007 799 816
    • (2007) Nature , vol.447 , pp. 799-816
  • 14
    • 84865757142 scopus 로고    scopus 로고
    • Landscape of transcription in human cells
    • S. Djebali, C.A. Davis, A. Merkel, and et al. Landscape of transcription in human cells Nature 489 2012 101 108
    • (2012) Nature , vol.489 , pp. 101-108
    • Djebali, S.1    Davis, C.A.2    Merkel, A.3
  • 15
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • E.S. Lander, L.M. Linton, B. Birren, et al. for the International Human Genome Sequencing Consortium Initial sequencing and analysis of the human genome Nature 409 2001 860 921
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.S.1    Linton, L.M.2    Birren, B.3
  • 16
    • 0035895505 scopus 로고    scopus 로고
    • The sequence of the human genome
    • J.C. Venter, M.D. Adams, E.W. Myers, and et al. The sequence of the human genome Science 291 2001 1304 1351
    • (2001) Science , vol.291 , pp. 1304-1351
    • Venter, J.C.1    Adams, M.D.2    Myers, E.W.3
  • 17
    • 60349120914 scopus 로고    scopus 로고
    • Long non-coding RNAs: Insights into functions
    • T.R. Mercer, M.E. Dinger, and J.S. Mattick Long non-coding RNAs: Insights into functions Nat Rev Genet 10 2009 155 159
    • (2009) Nat Rev Genet , vol.10 , pp. 155-159
    • Mercer, T.R.1    Dinger, M.E.2    Mattick, J.S.3
  • 18
    • 84894532371 scopus 로고    scopus 로고
    • On the classification of long non-coding RNAs
    • L. Ma, V.B. Bajic, and Z. Zhang On the classification of long non-coding RNAs RNA Biol 10 2013 925 933
    • (2013) RNA Biol , vol.10 , pp. 925-933
    • Ma, L.1    Bajic, V.B.2    Zhang, Z.3
  • 19
    • 84864927713 scopus 로고    scopus 로고
    • Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs
    • V.A. Moran, R.J. Perera, and A.M. Khalil Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs Nucleic Acids Res 40 2012 6391 6400
    • (2012) Nucleic Acids Res , vol.40 , pp. 6391-6400
    • Moran, V.A.1    Perera, R.J.2    Khalil, A.M.3
  • 20
    • 84890852686 scopus 로고    scopus 로고
    • Evolutionary conservation of long non-coding RNAs; sequence, structure, function
    • P. Johnsson, L. Lipovich, D. Grandér, and et al. Evolutionary conservation of long non-coding RNAs; sequence, structure, function Biochim Biophys Acta 1840 2014 1063 1071
    • (2014) Biochim Biophys Acta , vol.1840 , pp. 1063-1071
    • Johnsson, P.1    Lipovich, L.2    Grandér, D.3
  • 21
    • 29444457713 scopus 로고    scopus 로고
    • Rapid evolution of noncoding RNAs: Lack of conservation does not mean lack of function
    • K.C. Pang, M.C. Frith, and J.S. Mattick Rapid evolution of noncoding RNAs: Lack of conservation does not mean lack of function Trends Genet 22 2006 1 5
    • (2006) Trends Genet , vol.22 , pp. 1-5
    • Pang, K.C.1    Frith, M.C.2    Mattick, J.S.3
  • 22
    • 84455206362 scopus 로고    scopus 로고
    • Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution
    • I. Ulitsky, A. Shkumatava, C.H. Jan, and et al. Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution Cell 147 2011 1537 1550
    • (2011) Cell , vol.147 , pp. 1537-1550
    • Ulitsky, I.1    Shkumatava, A.2    Jan, C.H.3
  • 23
    • 84872531655 scopus 로고    scopus 로고
    • Circular RNAs are abundant, conserved, and associated with ALU repeats
    • W.R. Jeck, J.A. Sorrentino, K. Wang, and et al. Circular RNAs are abundant, conserved, and associated with ALU repeats RNA 19 2012 141 157
    • (2012) RNA , vol.19 , pp. 141-157
    • Jeck, W.R.1    Sorrentino, J.A.2    Wang, K.3
  • 24
    • 84875369248 scopus 로고    scopus 로고
    • Circular RNAs are a large class of animal RNAs with regulatory potency
    • S. Memczak, M. Jens, A. Elefsinioti, and et al. Circular RNAs are a large class of animal RNAs with regulatory potency Nature 495 2013 333 338
    • (2013) Nature , vol.495 , pp. 333-338
    • Memczak, S.1    Jens, M.2    Elefsinioti, A.3
  • 25
    • 0027389804 scopus 로고
    • Mis-splicing yields circular RNA molecules
    • C. Cocquerelle, B. Mascrez, D. Hétuin, and et al. Mis-splicing yields circular RNA molecules FASEB J 7 1993 155 160
    • (1993) FASEB J , vol.7 , pp. 155-160
    • Cocquerelle, C.1    Mascrez, B.2    Hétuin, D.3
  • 26
    • 0026456701 scopus 로고
    • The human XIST gene: Analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus
    • C.J. Brown, B.D. Hendrich, J.L. Rupert, and et al. The human XIST gene: Analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus Cell 71 1992 527 542
    • (1992) Cell , vol.71 , pp. 527-542
    • Brown, C.J.1    Hendrich, B.D.2    Rupert, J.L.3
  • 27
    • 55349109963 scopus 로고    scopus 로고
    • Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome
    • J. Zhao, B.K. Sun, J.A. Erwin, and et al. Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome Science 322 2008 750 756
    • (2008) Science , vol.322 , pp. 750-756
    • Zhao, J.1    Sun, B.K.2    Erwin, J.A.3
  • 28
    • 0021237658 scopus 로고
    • Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis
    • M.A. Surani, S.C. Barton, and M.L. Norris Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis Nature 308 1984 548 550
    • (1984) Nature , vol.308 , pp. 548-550
    • Surani, M.A.1    Barton, S.C.2    Norris, M.L.3
  • 29
    • 84890828236 scopus 로고    scopus 로고
    • H19 lncRNA controls gene expression of the imprinted gene network by recruiting MBD1
    • P. Monnier, C. Martinet, J. Pontis, and et al. H19 lncRNA controls gene expression of the imprinted gene network by recruiting MBD1 Proc Natl Acad Sci USA 110 2013 20693 20698
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 20693-20698
    • Monnier, P.1    Martinet, C.2    Pontis, J.3
  • 30
    • 68949212914 scopus 로고    scopus 로고
    • Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: Functional role of a nuclear noncoding RNA
    • L.L. Chen, and G.G. Carmichael Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: Functional role of a nuclear noncoding RNA Mol Cell 35 2009 467 478
    • (2009) Mol Cell , vol.35 , pp. 467-478
    • Chen, L.L.1    Carmichael, G.G.2
  • 31
    • 61849113891 scopus 로고    scopus 로고
    • MEN ε/β nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles
    • H. Sunwoo, M.E. Dinger, J.E. Wilusz, and et al. MEN ε/β nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles Genome Res 19 2009 347 359
    • (2009) Genome Res , vol.19 , pp. 347-359
    • Sunwoo, H.1    Dinger, M.E.2    Wilusz, J.E.3
  • 32
    • 78650511795 scopus 로고    scopus 로고
    • Direct visualization of the co-transcriptional assembly of a nuclear body by noncoding RNAs
    • Y.S. Mao, H. Sunwoo, B. Zhang, and et al. Direct visualization of the co-transcriptional assembly of a nuclear body by noncoding RNAs Nat Cell Biol 13 2011 95 101
    • (2011) Nat Cell Biol , vol.13 , pp. 95-101
    • Mao, Y.S.1    Sunwoo, H.2    Zhang, B.3
  • 33
    • 77953096072 scopus 로고    scopus 로고
    • Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a
    • K.L. Yap, S. Li, A.M. Munõz-Cabello, and et al. Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a Mol Cell 38 2010 662 674
    • (2010) Mol Cell , vol.38 , pp. 662-674
    • Yap, K.L.1    Li, S.2    Munõz-Cabello, A.M.3
  • 34
    • 34250729138 scopus 로고    scopus 로고
    • Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs
    • J.L. Rinn, M. Kertesz, J.K. Wang, and et al. Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs Cell 129 2007 1311 1323
    • (2007) Cell , vol.129 , pp. 1311-1323
    • Rinn, J.L.1    Kertesz, M.2    Wang, J.K.3
  • 35
    • 84890659939 scopus 로고    scopus 로고
    • Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination
    • J.H. Yoon, K. Abdelmohsen, J. Kim, and et al. Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination Nat Commun 4 2013 2939
    • (2013) Nat Commun , vol.4 , pp. 2939
    • Yoon, J.H.1    Abdelmohsen, K.2    Kim, J.3
  • 36
    • 79959756263 scopus 로고    scopus 로고
    • Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
    • T. Hung, Y. Wang, M.F. Lin, and et al. Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters Nat Genet 43 2011 621 629
    • (2011) Nat Genet , vol.43 , pp. 621-629
    • Hung, T.1    Wang, Y.2    Lin, M.F.3
  • 37
    • 84900334614 scopus 로고    scopus 로고
    • A new Lnc in metastasis: Long noncoding RNA mediates the prometastatic functions of TGF-β
    • W. Li, and Y. Kang A new Lnc in metastasis: Long noncoding RNA mediates the prometastatic functions of TGF-β Cancer Cell 25 2014 557 559
    • (2014) Cancer Cell , vol.25 , pp. 557-559
    • Li, W.1    Kang, Y.2
  • 38
    • 0025288707 scopus 로고
    • N-myc mRNA forms an RNA-RNA duplex with endogenous antisense transcripts
    • G.W. Krystal, B.C. Armstrong, and J.F. Battey N-myc mRNA forms an RNA-RNA duplex with endogenous antisense transcripts Mol Cell Biol 10 1990 4180 4191
    • (1990) Mol Cell Biol , vol.10 , pp. 4180-4191
    • Krystal, G.W.1    Armstrong, B.C.2    Battey, J.F.3
  • 39
    • 77956927823 scopus 로고    scopus 로고
    • The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation
    • V. Tripathi, J.D. Ellis, Z. Shen, and et al. The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation Mol Cell 39 2010 925 938
    • (2010) Mol Cell , vol.39 , pp. 925-938
    • Tripathi, V.1    Ellis, J.D.2    Shen, Z.3
  • 40
    • 84907536806 scopus 로고    scopus 로고
    • RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent pre-mRNAs and chromatin sites
    • J.M. Engreitz, K. Sirokman, P. McDonel, and et al. RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent pre-mRNAs and chromatin sites Cell 159 2014 188 199
    • (2014) Cell , vol.159 , pp. 188-199
    • Engreitz, J.M.1    Sirokman, K.2    McDonel, P.3
  • 41
    • 77952698932 scopus 로고    scopus 로고
    • Evidence for natural antisense transcript-mediated inhibition of microRNA function
    • M.A. Faghihi, M. Zhang, J. Huang, and et al. Evidence for natural antisense transcript-mediated inhibition of microRNA function Genome Biol 11 2010 R56
    • (2010) Genome Biol , vol.11 , pp. R56
    • Faghihi, M.A.1    Zhang, M.2    Huang, J.3
  • 42
    • 84912544114 scopus 로고    scopus 로고
    • H19 long noncoding RNA controls the mRNA decay promoting function of KSRP
    • M. Giovarelli, G. Bucci, A. Ramos, and et al. H19 long noncoding RNA controls the mRNA decay promoting function of KSRP Proc Natl Acad Sci USA 111 2014 E5023 E5028
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. E5023-E5028
    • Giovarelli, M.1    Bucci, G.2    Ramos, A.3
  • 43
    • 84869088820 scopus 로고    scopus 로고
    • Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat
    • C. Carrieri, L. Cimatti, M. Biagioli, and et al. Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat Nature 491 2012 454 457
    • (2012) Nature , vol.491 , pp. 454-457
    • Carrieri, C.1    Cimatti, L.2    Biagioli, M.3
  • 44
    • 77956062795 scopus 로고    scopus 로고
    • Genome-wide association identifies a deletion in the 3′ untranslated region of striatin in a canine model of arrhythmogenic right ventricular cardiomyopathy
    • K.M. Meurs, E. Mauceli, S. Lahmers, and et al. Genome-wide association identifies a deletion in the 3′ untranslated region of striatin in a canine model of arrhythmogenic right ventricular cardiomyopathy Hum Genet 128 2010 315 324
    • (2010) Hum Genet , vol.128 , pp. 315-324
    • Meurs, K.M.1    Mauceli, E.2    Lahmers, S.3
  • 45
    • 84897379124 scopus 로고    scopus 로고
    • Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation
    • C.L. Miller, U. Haas, R. Diaz, and et al. Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation PLoS Genet 10 2014 e1004263
    • (2014) PLoS Genet , vol.10 , pp. e1004263
    • Miller, C.L.1    Haas, U.2    Diaz, R.3
  • 46
    • 34250010480 scopus 로고    scopus 로고
    • A common variant on chromosome 9p21 affects the risk of myocardial infarction
    • A. Helgadottir, G. Thorleifsson, A. Manolescu, and et al. A common variant on chromosome 9p21 affects the risk of myocardial infarction Science 316 2007 1491 1493
    • (2007) Science , vol.316 , pp. 1491-1493
    • Helgadottir, A.1    Thorleifsson, G.2    Manolescu, A.3
  • 47
    • 34249996115 scopus 로고    scopus 로고
    • A common allele on chromosome 9 associated with coronary heart disease
    • R. McPherson, A. Pertsemlidis, N. Kavaslar, and et al. A common allele on chromosome 9 associated with coronary heart disease Science 316 2007 1488 1491
    • (2007) Science , vol.316 , pp. 1488-1491
    • McPherson, R.1    Pertsemlidis, A.2    Kavaslar, N.3
  • 48
    • 34547623750 scopus 로고    scopus 로고
    • Genomewide association analysis of coronary artery disease
    • N.J. Samani, J. Erdmann, A.S. Hall, et al. for WTCCC and the Cardiogenics Consortium Genomewide association analysis of coronary artery disease N Engl J Med 357 2007 443 453
    • (2007) N Engl J Med , vol.357 , pp. 443-453
    • Samani, N.J.1    Erdmann, J.2    Hall, A.S.3
  • 49
    • 84883780487 scopus 로고    scopus 로고
    • From genotype to phenotype in human atherosclerosis-recent findings
    • L.M. Holdt, and D. Teupser From genotype to phenotype in human atherosclerosis-recent findings Curr Opin Lipidol 24 2013 410 418
    • (2013) Curr Opin Lipidol , vol.24 , pp. 410-418
    • Holdt, L.M.1    Teupser, D.2
  • 50
    • 84885004085 scopus 로고    scopus 로고
    • The 9p21 locus does not affect risk of coronary artery disease through induction of type 1 interferons
    • C. Erridge, J. Gracey, P.S. Braund, and et al. The 9p21 locus does not affect risk of coronary artery disease through induction of type 1 interferons J Am Coll Cardiol 62 2013 1376 1381
    • (2013) J Am Coll Cardiol , vol.62 , pp. 1376-1381
    • Erridge, C.1    Gracey, J.2    Braund, P.S.3
  • 51
    • 84856136800 scopus 로고    scopus 로고
    • Recent studies of the human chromosome 9p21 locus, which is associated with atherosclerosis in human populations
    • L.M. Holdt, and D. Teupser Recent studies of the human chromosome 9p21 locus, which is associated with atherosclerosis in human populations Arterioscler Thromb Vasc Biol 32 2012 196 206
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 196-206
    • Holdt, L.M.1    Teupser, D.2
  • 52
    • 77649166974 scopus 로고    scopus 로고
    • ANRIL expression is associated with atherosclerosis risk at chromosome 9p21
    • L.M. Holdt, F. Beutner, M. Scholz, and et al. ANRIL expression is associated with atherosclerosis risk at chromosome 9p21 Arterioscler Thromb Vasc Biol 30 2010 620 627
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 620-627
    • Holdt, L.M.1    Beutner, F.2    Scholz, M.3
  • 53
    • 84855976300 scopus 로고    scopus 로고
    • Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B
    • A. Congrains, K. Kamide, R. Oguro, and et al. Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B Atherosclerosis 220 2012 449 455
    • (2012) Atherosclerosis , vol.220 , pp. 449-455
    • Congrains, A.1    Kamide, K.2    Oguro, R.3
  • 54
    • 84863011649 scopus 로고    scopus 로고
    • Additive effect of ANRIL and BRAP polymorphisms on ankle-brachial index in a Taiwanese population
    • P.C. Tsai, Y.C. Liao, T.H. Lin, and et al. Additive effect of ANRIL and BRAP polymorphisms on ankle-brachial index in a Taiwanese population Circ J 76 2012 446 452
    • (2012) Circ J , vol.76 , pp. 446-452
    • Tsai, P.C.1    Liao, Y.C.2    Lin, T.H.3
  • 55
    • 79951473520 scopus 로고    scopus 로고
    • 9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response
    • O. Harismendy, D. Notani, X. Song, and et al. 9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response Nature 470 2011 264 268
    • (2011) Nature , vol.470 , pp. 264-268
    • Harismendy, O.1    Notani, D.2    Song, X.3
  • 56
    • 84880799429 scopus 로고    scopus 로고
    • Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks
    • L.M. Holdt, S. Hoffmann, K. Sass, and et al. Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks PLoS Genet 9 2013 e1003588
    • (2013) PLoS Genet , vol.9 , pp. e1003588
    • Holdt, L.M.1    Hoffmann, S.2    Sass, K.3
  • 57
    • 78650696753 scopus 로고    scopus 로고
    • Expression of linear and novel circular forms of an INK4/ARF-associated non-coding RNA correlates with atherosclerosis risk
    • C.E. Burd, W.R. Jeck, Y. Liu, and et al. Expression of linear and novel circular forms of an INK4/ARF-associated non-coding RNA correlates with atherosclerosis risk PLoS Genet 6 2010 e1001233
    • (2010) PLoS Genet , vol.6 , pp. e1001233
    • Burd, C.E.1    Jeck, W.R.2    Liu, Y.3
  • 58
    • 84863421652 scopus 로고    scopus 로고
    • CVD-associated non-coding RNA, ANRIL, modulates expression of atherogenic pathways in VSMC
    • A. Congrains, K. Kamide, T. Katsuya, and et al. CVD-associated non-coding RNA, ANRIL, modulates expression of atherogenic pathways in VSMC Biochem Biophys Res Commun 419 2012 612 616
    • (2012) Biochem Biophys Res Commun , vol.419 , pp. 612-616
    • Congrains, A.1    Kamide, K.2    Katsuya, T.3
  • 59
    • 79955468280 scopus 로고    scopus 로고
    • Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene
    • Y. Kotake, T. Nakagawa, K. Kitagawa, and et al. Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene Oncogene 30 2011 1956 1962
    • (2011) Oncogene , vol.30 , pp. 1956-1962
    • Kotake, Y.1    Nakagawa, T.2    Kitagawa, K.3
  • 60
    • 84887008398 scopus 로고    scopus 로고
    • The large non-coding RNA ANRIL, which is associated with atherosclerosis, periodontitis and several forms of cancer, regulates ADIPOR1, VAMP3 and C11ORF10
    • G. Bochenek, R. Häsler, N.E. El Mokhtari, and et al. The large non-coding RNA ANRIL, which is associated with atherosclerosis, periodontitis and several forms of cancer, regulates ADIPOR1, VAMP3 and C11ORF10 Hum Mol Genet 22 2013 4516 4527
    • (2013) Hum Mol Genet , vol.22 , pp. 4516-4527
    • Bochenek, G.1    Häsler, R.2    El Mokhtari, N.E.3
  • 61
    • 84930685466 scopus 로고    scopus 로고
    • The cis and trans effects of the risk variants of coronary artery disease in the Chr9p21 region
    • W. Zhao, J.A. Smith, G. Mao, and et al. The cis and trans effects of the risk variants of coronary artery disease in the Chr9p21 region BMC Med Genomics 8 2015 21
    • (2015) BMC Med Genomics , vol.8 , pp. 21
    • Zhao, W.1    Smith, J.A.2    Mao, G.3
  • 62
    • 33751277900 scopus 로고    scopus 로고
    • Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction
    • N. Ishii, K. Ozaki, H. Sato, and et al. Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction J Hum Genet 51 2006 1087 1099
    • (2006) J Hum Genet , vol.51 , pp. 1087-1099
    • Ishii, N.1    Ozaki, K.2    Sato, H.3
  • 63
    • 84920998638 scopus 로고    scopus 로고
    • Association of polymorphisms in long non-coding RNA H19 with coronary artery disease risk in a Chinese population
    • W. Gao, M. Zhu, H. Wang, and et al. Association of polymorphisms in long non-coding RNA H19 with coronary artery disease risk in a Chinese population Mutat Res 772 2015 15 22
    • (2015) Mutat Res , vol.772 , pp. 15-22
    • Gao, W.1    Zhu, M.2    Wang, H.3
  • 64
    • 84927604450 scopus 로고    scopus 로고
    • The non-coding RNAs of the H19-IGF2 imprinted loci: A focus on biological roles and therapeutic potential in lung cancer
    • I.J. Matouk, D. Halle, M. Gilon, and et al. The non-coding RNAs of the H19-IGF2 imprinted loci: A focus on biological roles and therapeutic potential in lung cancer J Transl Med 13 2015 113
    • (2015) J Transl Med , vol.13 , pp. 113
    • Matouk, I.J.1    Halle, D.2    Gilon, M.3
  • 65
    • 0028057278 scopus 로고
    • H19, a developmentally regulated gene, is reexpressed in rat vascular smooth muscle cells after injury
    • D.K. Kim, L. Zhang, V.J. Dzau, and et al. H19, a developmentally regulated gene, is reexpressed in rat vascular smooth muscle cells after injury J Clin Invest 93 1994 355 360
    • (1994) J Clin Invest , vol.93 , pp. 355-360
    • Kim, D.K.1    Zhang, L.2    Dzau, V.J.3
  • 66
    • 0029866163 scopus 로고    scopus 로고
    • H19, a marker of developmental transition, is reexpressed in human atherosclerotic plaques and is regulated by the insulin family of growth factors in cultured rabbit smooth muscle cells
    • D.K. Han, Z.Z. Khaing, R.A. Pollock, and et al. H19, a marker of developmental transition, is reexpressed in human atherosclerotic plaques and is regulated by the insulin family of growth factors in cultured rabbit smooth muscle cells J Clin Invest 97 1996 1276 1285
    • (1996) J Clin Invest , vol.97 , pp. 1276-1285
    • Han, D.K.1    Khaing, Z.Z.2    Pollock, R.A.3
  • 67
    • 84895920262 scopus 로고    scopus 로고
    • Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci
    • V. Tragante, M.R. Barnes, S.K. Ganesh, and et al. Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci Am J Hum Genet 94 2014 349 360
    • (2014) Am J Hum Genet , vol.94 , pp. 349-360
    • Tragante, V.1    Barnes, M.R.2    Ganesh, S.K.3
  • 68
    • 84885374473 scopus 로고    scopus 로고
    • The imprinted H19 lncRNA antagonizes let-7 microRNAs
    • A.N. Kallen, X.B. Zhou, J. Xu, and et al. The imprinted H19 lncRNA antagonizes let-7 microRNAs Mol Cell 52 2013 101 112
    • (2013) Mol Cell , vol.52 , pp. 101-112
    • Kallen, A.N.1    Zhou, X.B.2    Xu, J.3
  • 69
    • 84930537532 scopus 로고    scopus 로고
    • Regulation of tumor cell migration and invasion by the H19/let-7 axis is antagonized by metformin-induced DNA methylation
    • L. Yan, J. Zhou, Y. Gao, and et al. Regulation of tumor cell migration and invasion by the H19/let-7 axis is antagonized by metformin-induced DNA methylation Oncogene 34 2015 3076 3084
    • (2015) Oncogene , vol.34 , pp. 3076-3084
    • Yan, L.1    Zhou, J.2    Gao, Y.3
  • 70
    • 84888162654 scopus 로고    scopus 로고
    • Let-7 in cardiovascular diseases, heart development and cardiovascular differentiation from stem cells
    • M.H. Bao, X. Feng, Y.W. Zhang, and et al. Let-7 in cardiovascular diseases, heart development and cardiovascular differentiation from stem cells Int J Mol Sci 14 2013 23086 23102
    • (2013) Int J Mol Sci , vol.14 , pp. 23086-23102
    • Bao, M.H.1    Feng, X.2    Zhang, Y.W.3
  • 71
    • 84873300214 scopus 로고    scopus 로고
    • Braveheart, a long noncoding RNA required for cardiovascular lineage commitment
    • C.A. Klattenhoff, J.C. Scheuermann, L.E. Surface, and et al. Braveheart, a long noncoding RNA required for cardiovascular lineage commitment Cell 152 2013 570 583
    • (2013) Cell , vol.152 , pp. 570-583
    • Klattenhoff, C.A.1    Scheuermann, J.C.2    Surface, L.E.3
  • 72
    • 84873829893 scopus 로고    scopus 로고
    • The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse
    • P. Grote, L. Wittler, D. Hendrix, and et al. The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse Dev Cell 24 2013 206 214
    • (2013) Dev Cell , vol.24 , pp. 206-214
    • Grote, P.1    Wittler, L.2    Hendrix, D.3
  • 73
    • 84929359342 scopus 로고    scopus 로고
    • Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development
    • L. Kurian, A. Aguirre, I. Sancho-Martinez, and et al. Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development Circulation 131 2015 1278 1290
    • (2015) Circulation , vol.131 , pp. 1278-1290
    • Kurian, L.1    Aguirre, A.2    Sancho-Martinez, I.3
  • 74
    • 84655164920 scopus 로고    scopus 로고
    • Large-scale discovery of enhancers from human heart tissue
    • D. May, M.J. Blow, T. Kaplan, and et al. Large-scale discovery of enhancers from human heart tissue Nat Genet 44 2011 89 93
    • (2011) Nat Genet , vol.44 , pp. 89-93
    • May, D.1    Blow, M.J.2    Kaplan, T.3
  • 75
    • 77956641239 scopus 로고    scopus 로고
    • ChIP-Seq identification of weakly conserved heart enhancers
    • M.J. Blow, D.J. McCulley, Z. Li, and et al. ChIP-Seq identification of weakly conserved heart enhancers Nat Genet 42 2010 806 810
    • (2010) Nat Genet , vol.42 , pp. 806-810
    • Blow, M.J.1    McCulley, D.J.2    Li, Z.3
  • 76
    • 84906314395 scopus 로고    scopus 로고
    • Epigenetic coordination of embryonic heart transcription by dynamically regulated long noncoding RNAs
    • S.J. Matkovich, J.R. Edwards, T.C. Grossenheider, and et al. Epigenetic coordination of embryonic heart transcription by dynamically regulated long noncoding RNAs Proc Natl Acad Sci USA 111 2014 12264 12269
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 12264-12269
    • Matkovich, S.J.1    Edwards, J.R.2    Grossenheider, T.C.3
  • 77
    • 84924134321 scopus 로고    scopus 로고
    • Long non-coding RNAs in cardiovascular diseases
    • S. Uchida, and S. Dimmeler Long non-coding RNAs in cardiovascular diseases Circ Res 116 2015 737 750
    • (2015) Circ Res , vol.116 , pp. 737-750
    • Uchida, S.1    Dimmeler, S.2
  • 78
    • 84945482686 scopus 로고    scopus 로고
    • Identification and characterization of hypoxia-regulated endothelial circular RNA
    • J.N. Boeckel, N. Jaé, A.W. Heumüller, and et al. Identification and characterization of hypoxia-regulated endothelial circular RNA Circ Res 117 2015 884 890
    • (2015) Circ Res , vol.117 , pp. 884-890
    • Boeckel, J.N.1    Jaé, N.2    Heumüller, A.W.3
  • 79
    • 84895552736 scopus 로고    scopus 로고
    • Deep RNA sequencing reveals dynamic regulation of myocardial noncoding RNAs in failing human heart and remodeling with mechanical circulatory support
    • K.C. Yang, K.A. Yamada, A.Y. Patel, and et al. Deep RNA sequencing reveals dynamic regulation of myocardial noncoding RNAs in failing human heart and remodeling with mechanical circulatory support Circulation 129 2014 1009 1021
    • (2014) Circulation , vol.129 , pp. 1009-1021
    • Yang, K.C.1    Yamada, K.A.2    Patel, A.Y.3
  • 80
    • 84928233559 scopus 로고    scopus 로고
    • Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long non-coding RNAs
    • S. Ounzain, R. Micheletti, T. Beckmann, and et al. Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long non-coding RNAs Eur Heart J 36 2015 353 368 a
    • (2015) Eur Heart J , vol.36 , pp. 353-368
    • Ounzain, S.1    Micheletti, R.2    Beckmann, T.3
  • 81
    • 85026337327 scopus 로고    scopus 로고
    • Right ventricular long noncoding RNA expression in human heart failure
    • T.G. Di Salvo, Y. Guo, Y.R. Su, and et al. Right ventricular long noncoding RNA expression in human heart failure Pulm Circ 5 2015 135 161
    • (2015) Pulm Circ , vol.5 , pp. 135-161
    • Di Salvo, T.G.1    Guo, Y.2    Su, Y.R.3
  • 82
    • 84900310934 scopus 로고    scopus 로고
    • The long non-coding HOTAIR is modulated by cyclic stretch and WNT/β-CATENIN in human aortic valve cells and is a novel repressor of calcification genes
    • K. Carrion, J. Dyo, V. Patel, and et al. The long non-coding HOTAIR is modulated by cyclic stretch and WNT/β-CATENIN in human aortic valve cells and is a novel repressor of calcification genes PLoS One 9 2014 e96577
    • (2014) PLoS One , vol.9 , pp. e96577
    • Carrion, K.1    Dyo, J.2    Patel, V.3
  • 83
    • 77951118936 scopus 로고    scopus 로고
    • Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
    • R.A. Gupta, N. Shah, K.C. Wang, and et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis Nature 464 2010 1071 1076
    • (2010) Nature , vol.464 , pp. 1071-1076
    • Gupta, R.A.1    Shah, N.2    Wang, K.C.3
  • 84
    • 84900844231 scopus 로고    scopus 로고
    • Circulating long noncoding RNA, LIPCAR, predicts survival in patients with heart failure
    • R. Kumarswamy, C. Bauters, I. Volkmann, and et al. Circulating long noncoding RNA, LIPCAR, predicts survival in patients with heart failure Circ Res 114 2014 1569 1575
    • (2014) Circ Res , vol.114 , pp. 1569-1575
    • Kumarswamy, R.1    Bauters, C.2    Volkmann, I.3
  • 85
    • 84900857368 scopus 로고    scopus 로고
    • LIPCAR: A mitochondrial lnc in the noncoding RNA chain?
    • G.W. Dorn II LIPCAR: A mitochondrial lnc in the noncoding RNA chain? Circ Res 114 2014 1548 1550
    • (2014) Circ Res , vol.114 , pp. 1548-1550
    • Dorn, G.W.1
  • 86
    • 84910147922 scopus 로고    scopus 로고
    • Long noncoding RNAs in patients with acute myocardial infarction
    • M. Vausort, D.R. Wagner, and Y. Devaux Long noncoding RNAs in patients with acute myocardial infarction Circ Res 115 2014 668 677
    • (2014) Circ Res , vol.115 , pp. 668-677
    • Vausort, M.1    Wagner, D.R.2    Devaux, Y.3
  • 87
    • 84942898058 scopus 로고    scopus 로고
    • Plasma long non-coding RNA, CoroMarker, a novel biomarker for diagnosis of coronary artery disease
    • Y. Yang, Y. Cai, G. Wu, and et al. Plasma long non-coding RNA, CoroMarker, a novel biomarker for diagnosis of coronary artery disease Clin Sci (Lond) 129 2015 675 685
    • (2015) Clin Sci (Lond) , vol.129 , pp. 675-685
    • Yang, Y.1    Cai, Y.2    Wu, G.3
  • 88
    • 84920517878 scopus 로고    scopus 로고
    • Circulating long noncoding RNATapSaki is a predictor of mortality in critically ill patients with acute kidney injury
    • J.M. Lorenzen, C. Schauerte, J.T. Kielstein, and et al. Circulating long noncoding RNATapSaki is a predictor of mortality in critically ill patients with acute kidney injury Clin Chem 61 2015 191 201
    • (2015) Clin Chem , vol.61 , pp. 191-201
    • Lorenzen, J.M.1    Schauerte, C.2    Kielstein, J.T.3
  • 89
    • 84949238604 scopus 로고    scopus 로고
    • Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood
    • S. Memczak, P. Papavasileiou, O. Peters, and et al. Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood PLoS One 10 2015 e0141214
    • (2015) PLoS One , vol.10 , pp. e0141214
    • Memczak, S.1    Papavasileiou, P.2    Peters, O.3
  • 90
    • 84879704542 scopus 로고    scopus 로고
    • Heparin selectively affects the quantification of microRNAs in human blood samples
    • J.N. Boeckel, C.E. Thomé, D. Leistner, and et al. Heparin selectively affects the quantification of microRNAs in human blood samples Clin Chem 59 2013 1125 1127
    • (2013) Clin Chem , vol.59 , pp. 1125-1127
    • Boeckel, J.N.1    Thomé, C.E.2    Leistner, D.3
  • 91
    • 84921353503 scopus 로고    scopus 로고
    • Considerations when investigating lncRNA function in vivo
    • A.R. Bassett, A. Akhtar, D.P. Barlow, and et al. Considerations when investigating lncRNA function in vivo Elife 3 2014 e03058
    • (2014) Elife , vol.3 , pp. e03058
    • Bassett, A.R.1    Akhtar, A.2    Barlow, D.P.3
  • 92
    • 84884907424 scopus 로고    scopus 로고
    • CRISPR RNA-guided activation of endogenous human genes
    • M.L. Maeder, S.J. Linder, V.M. Cascio, and et al. CRISPR RNA-guided activation of endogenous human genes Nat Methods 10 2013 977 979
    • (2013) Nat Methods , vol.10 , pp. 977-979
    • Maeder, M.L.1    Linder, S.J.2    Cascio, V.M.3
  • 93
    • 84899993786 scopus 로고    scopus 로고
    • Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth
    • K.M. Michalik, X. You, Y. Manavski, and et al. Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth Circ Res 114 2014 1389 1397
    • (2014) Circ Res , vol.114 , pp. 1389-1397
    • Michalik, K.M.1    You, X.2    Manavski, Y.3
  • 94
    • 84894051235 scopus 로고    scopus 로고
    • Aberrant expression of long noncoding RNAs in early diabetic retinopathy
    • B. Yan, Z.F. Tao, X.M. Li, and et al. Aberrant expression of long noncoding RNAs in early diabetic retinopathy Invest Ophthalmol Vis Sci 55 2014 941 951
    • (2014) Invest Ophthalmol Vis Sci , vol.55 , pp. 941-951
    • Yan, B.1    Tao, Z.F.2    Li, X.M.3
  • 95
    • 84925858306 scopus 로고    scopus 로고
    • Pathogenic role of lncRNA-MALAT1 in endothelial cell dysfunction in diabetes mellitus
    • J.Y. Liu, J. Yao, X.M. Li, and et al. Pathogenic role of lncRNA-MALAT1 in endothelial cell dysfunction in diabetes mellitus Cell Death Dis 5 2014 e1506
    • (2014) Cell Death Dis , vol.5 , pp. e1506
    • Liu, J.Y.1    Yao, J.2    Li, X.M.3
  • 96
    • 84929946346 scopus 로고    scopus 로고
    • Long non-coding RNA MALAT1 regulates hyperglycaemia induced inflammatory process in the endothelial cells
    • P. Puthanveetil, S. Chen, B. Feng, and et al. Long non-coding RNA MALAT1 regulates hyperglycaemia induced inflammatory process in the endothelial cells J Cell Mol Med 19 2015 1418 1425
    • (2015) J Cell Mol Med , vol.19 , pp. 1418-1425
    • Puthanveetil, P.1    Chen, S.2    Feng, B.3
  • 97
    • 84929942491 scopus 로고    scopus 로고
    • Long noncoding RNAs in diabetic retinopathy
    • N. Jaé, and S. Dimmeler Long noncoding RNAs in diabetic retinopathy Circ Res 116 2015 1104 1106
    • (2015) Circ Res , vol.116 , pp. 1104-1106
    • Jaé, N.1    Dimmeler, S.2
  • 98
    • 84930709932 scopus 로고    scopus 로고
    • LncRNA-MIAT regulates microvascular dysfunction by functioning as a competing endogenous RNA
    • B. Yan, J. Yao, J.Y. Liu, and et al. lncRNA-MIAT regulates microvascular dysfunction by functioning as a competing endogenous RNA Circ Res 116 2015 1143 1156
    • (2015) Circ Res , vol.116 , pp. 1143-1156
    • Yan, B.1    Yao, J.2    Liu, J.Y.3
  • 99
    • 84945308611 scopus 로고    scopus 로고
    • Development of long noncoding RNA-based strategies to modulate tissue vascularization
    • J. Fiedler, K. Breckwoldt, C.W. Remmele, and et al. Development of long noncoding RNA-based strategies to modulate tissue vascularization J Am Coll Cardiol 66 2015 2005 2015
    • (2015) J Am Coll Cardiol , vol.66 , pp. 2005-2015
    • Fiedler, J.1    Breckwoldt, K.2    Remmele, C.W.3
  • 100
    • 84917729694 scopus 로고    scopus 로고
    • LincRNA-p21 regulates neointima formation, vascular smooth muscle cell proliferation, apoptosis, and atherosclerosis by enhancing p53 activity
    • G. Wu, J. Cai, Y. Han, and et al. LincRNA-p21 regulates neointima formation, vascular smooth muscle cell proliferation, apoptosis, and atherosclerosis by enhancing p53 activity Circulation 130 2014 1452 1465
    • (2014) Circulation , vol.130 , pp. 1452-1465
    • Wu, G.1    Cai, J.2    Han, Y.3
  • 101
    • 84920144487 scopus 로고    scopus 로고
    • RP5-833A20.1/miR-382-5p/NFIA-dependent signal transduction pathway contributes to the regulation of cholesterol homeostasis and inflammatory reaction
    • Y.W. Hu, J.Y. Zhao, S.F. Li, and et al. RP5-833A20.1/miR-382-5p/NFIA-dependent signal transduction pathway contributes to the regulation of cholesterol homeostasis and inflammatory reaction Arterioscler Thromb Vasc Biol 35 2015 87 101
    • (2015) Arterioscler Thromb Vasc Biol , vol.35 , pp. 87-101
    • Hu, Y.W.1    Zhao, J.Y.2    Li, S.F.3
  • 102
    • 84901504177 scopus 로고    scopus 로고
    • Identification and initial functional characterization of a human vascular cell-enriched long noncoding RNA
    • R.D. Bell, X. Long, M. Lin, and et al. Identification and initial functional characterization of a human vascular cell-enriched long noncoding RNA Arterioscler Thromb Vasc Biol 34 2014 1249 1259
    • (2014) Arterioscler Thromb Vasc Biol , vol.34 , pp. 1249-1259
    • Bell, R.D.1    Long, X.2    Lin, M.3
  • 103
    • 84924411357 scopus 로고    scopus 로고
    • A liver-enriched long non-coding RNA, lncLSTR, regulates systemic lipid metabolism in mice
    • P. Li, X. Ruan, L. Yang, and et al. A liver-enriched long non-coding RNA, lncLSTR, regulates systemic lipid metabolism in mice Cell Metab 21 2015 455 467
    • (2015) Cell Metab , vol.21 , pp. 455-467
    • Li, P.1    Ruan, X.2    Yang, L.3
  • 104
    • 84905483304 scopus 로고    scopus 로고
    • MDRL lncRNA regulates the processing of miR-484 primary transcript by targeting miR-361
    • K. Wang, T. Sun, N. Li, and et al. MDRL lncRNA regulates the processing of miR-484 primary transcript by targeting miR-361 PLoS Genet 10 2014 e1004467
    • (2014) PLoS Genet , vol.10 , pp. e1004467
    • Wang, K.1    Sun, T.2    Li, N.3
  • 105
    • 84899912204 scopus 로고    scopus 로고
    • The long noncoding RNA CHRF regulates cardiac hypertrophy by targeting miR-489
    • K. Wang, F. Liu, L.Y. Zhou, and et al. The long noncoding RNA CHRF regulates cardiac hypertrophy by targeting miR-489 Circ Res 114 2014 1377 1388
    • (2014) Circ Res , vol.114 , pp. 1377-1388
    • Wang, K.1    Liu, F.2    Zhou, L.Y.3
  • 106
    • 84927595144 scopus 로고    scopus 로고
    • APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p
    • K. Wang, C.Y. Liu, L.Y. Zhou, and et al. APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p Nat Commun 6 2015 6779
    • (2015) Nat Commun , vol.6 , pp. 6779
    • Wang, K.1    Liu, C.Y.2    Zhou, L.Y.3
  • 107
    • 84908020927 scopus 로고    scopus 로고
    • A long noncoding RNA protects the heart from pathological hypertrophy
    • P. Han, W. Li, C.H. Lin, and et al. A long noncoding RNA protects the heart from pathological hypertrophy Nature 514 2014 102 106
    • (2014) Nature , vol.514 , pp. 102-106
    • Han, P.1    Li, W.2    Lin, C.H.3
  • 108
    • 84883654580 scopus 로고    scopus 로고
    • Inhibition of microRNA-92a protects against ischemia/reperfusion injury in a large-animal model
    • R. Hinkel, D. Penzkofer, S. Zühlke, and et al. Inhibition of microRNA-92a protects against ischemia/reperfusion injury in a large-animal model Circulation 128 2013 1066 1075
    • (2013) Circulation , vol.128 , pp. 1066-1075
    • Hinkel, R.1    Penzkofer, D.2    Zühlke, S.3
  • 109
    • 84877258007 scopus 로고    scopus 로고
    • Treatment of HCV infection by targeting microRNA
    • H.L.A. Janssen, H.W. Reesink, E.J. Lawitz, and et al. Treatment of HCV infection by targeting microRNA N Engl J Med 368 2013 1685 1694
    • (2013) N Engl J Med , vol.368 , pp. 1685-1694
    • Janssen, H.L.A.1    Reesink, H.W.2    Lawitz, E.J.3
  • 110
    • 84868383682 scopus 로고    scopus 로고
    • Targeting LDL cholesterol with LNA
    • A.M. Krieg Targeting LDL cholesterol with LNA Mol Ther Nucleic Acids 1 2012 e6
    • (2012) Mol Ther Nucleic Acids , vol.1 , pp. e6
    • Krieg, A.M.1
  • 111
    • 84896032490 scopus 로고    scopus 로고
    • Pilot trial of EZN-2968, an antisense oligonucleotide inhibitor of hypoxia-inducible factor-1 alpha (HIF-1α), in patients with refractory solid tumors
    • W. Jeong, A. Rapisarda, S.R. Park, and et al. Pilot trial of EZN-2968, an antisense oligonucleotide inhibitor of hypoxia-inducible factor-1 alpha (HIF-1α), in patients with refractory solid tumors Cancer Chemother Pharmacol 73 2014 343 348
    • (2014) Cancer Chemother Pharmacol , vol.73 , pp. 343-348
    • Jeong, W.1    Rapisarda, A.2    Park, S.R.3
  • 112
    • 79960918427 scopus 로고    scopus 로고
    • Phase I study of LY2181308, an antisense oligonucleotide against survivin, in patients with advanced solid tumors
    • M. Tanioka, H. Nokihara, N. Yamamoto, and et al. Phase I study of LY2181308, an antisense oligonucleotide against survivin, in patients with advanced solid tumors Cancer Chemother Pharmacol 68 2011 505 511
    • (2011) Cancer Chemother Pharmacol , vol.68 , pp. 505-511
    • Tanioka, M.1    Nokihara, H.2    Yamamoto, N.3
  • 113
    • 84901838697 scopus 로고    scopus 로고
    • Assessing the ceRNA hypothesis with quantitative measurements of miRNA and target abundance
    • R. Denzler, V. Agarwal, J. Stefano, and et al. Assessing the ceRNA hypothesis with quantitative measurements of miRNA and target abundance Mol Cell 54 2014 766 776
    • (2014) Mol Cell , vol.54 , pp. 766-776
    • Denzler, R.1    Agarwal, V.2    Stefano, J.3
  • 114
    • 84922708088 scopus 로고    scopus 로고
    • A micropeptide encoded by a putative long noncoding RNA regulates muscle performance
    • D.M. Anderson, K.M. Anderson, C.L. Chang, and et al. A micropeptide encoded by a putative long noncoding RNA regulates muscle performance Cell 160 2015 595 606
    • (2015) Cell , vol.160 , pp. 595-606
    • Anderson, D.M.1    Anderson, K.M.2    Chang, C.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.