Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B

Atherosclerosis

Volumn 220, Issue 2, 2012, Pages 449-455

  Congrains, Ada ^a   Kamide, Kei ^a   Oguro, Ryousuke ^a   Yasuda, Osamu ^b   Miyata, Keishi ^c   Yamamoto, Eiichiro ^c   Kawai, Tatsuo ^a   Kusunoki, Hiroshi ^d   Yamamoto, Hiroko ^a   Takeya, Yasushi ^a   Yamamoto, Koichi ^a   Onishi, Miyuki ^a   Sugimoto, Ken ^a   Katsuya, Tomohiro ^d   Awata, Nobuhisa ^e   Ikebe, Kazunori ^a   Gondo, Yasuyuki ^a   Oike, Yuichi ^c   Ohishi, Mitsuru ^a   Rakugi, Hiromi ^a  

^a OSAKA UNIVERSITY   (Japan)

^b KUMAMOTO UNIVERSITY HOSPITAL   (Japan)

^c KUMAMOTO UNIVERSITY   (Japan)

^d OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

Author keywords

ANRIL; Atherosclerosis; CDKN2A; CDKN2B; Chromosome 9p21

Indexed keywords

ANRIL ENZYME; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; UNCLASSIFIED DRUG;

9P21 LOCUS GENE; AGED; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CAROTID ARTERY OBSTRUCTION; CELL GROWTH; CELL PROLIFERATION; DNA EXTRACTION; EXON; GENE EXPRESSION; GENE LOCUS; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GENOTYPE; HEART MUSCLE CELL; HUMAN; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA EXTRACTION; SINGLE NUCLEOTIDE POLYMORPHISM; VASCULAR SMOOTH MUSCLE;

AGED; ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CAROTID ARTERY, COMMON; CAROTID INTIMA-MEDIA THICKNESS; CAROTID STENOSIS; CELL PROLIFERATION; CELLS, CULTURED; CHROMOSOMES, HUMAN, PAIR 9; CYCLIN-DEPENDENT KINASE INHIBITOR P15; CYCLIN-DEPENDENT KINASE INHIBITOR P16; EXONS; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; JAPAN; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RNA INTERFERENCE; RNA, UNTRANSLATED;

EID: 84855976300     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2011.11.017     Document Type: Article

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