α/β-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes

Cell Reports

Volumn 14, Issue 12, 2016, Pages 2872-2888

  Zhao, Shangang ^a   Mugabo, Yves ^a   Ballentine, Gwynne ^b   Attane, Camille ^a   Iglesias, Jose ^a   Poursharifi, Pegah ^a   Zhang, Dongwei ^a,d   Nguyen, Thuy Anne ^a   Erb, Heidi ^a   Prentki, Raphael ^a   Peyot, Marie Line ^a   Joly, Erik ^a   Tobin, Stephanie ^a   Fulton, Stephanie ^a   Brown, J Mark ^c   Madiraju, S R Murthy ^a   Prentki, Marc ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b Metanome Inc   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

^d BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLGLYCEROL LIPASE; ALPHA BETA HYDROLASE DOMAIN 6; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1; 1-O-MYRISTOYL-2-ACETYL-GLYCEROL; ABHD6 PROTEIN, MOUSE; BIPHENYL DERIVATIVE; CARBAMIC ACID DERIVATIVE; DIACYLGLYCEROL; N-METHYL-N-((3-(4-PYRIDINYL)PHENYL)METHYL)-4'-(AMINOCARBONYL)(1,1'-BIPHENYL)-4-YL ESTER, CARBAMIC ACID; UCP1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ARTICLE; BROWN ADIPOSE TISSUE; CELL DIFFERENTIATION; CONTROLLED STUDY; DIET INDUCED OBESITY; ENERGY EXPENDITURE; ENZYME ACTIVITY; ENZYME REPRESSION; FATTY ACID OXIDATION; FATTY LIVER; FEMALE; FOOD INTAKE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; GLUCOSE TRANSPORT; HYPERINSULINEMIA; HYPERINSULINEMIC-EUGLYCEMIC CLAMP TECHNIQUE; INSULIN RELEASE; INSULIN SENSITIVITY; LIPID DIET; LIPOGENESIS; LIPOLYSIS; LOCOMOTION; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN DOMAIN; RECTUM TEMPERATURE; SIGNAL TRANSDUCTION; SOLEUS MUSCLE; THERMOGENESIS; TRANSACTIVATION ASSAY; WEIGHT GAIN; 3T3-L1 CELL LINE; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; DIABETES MELLITUS, TYPE 2; DRUG EFFECTS; ENERGY METABOLISM; GENETICS; HEK293 CELL LINE; HUMAN; KNOCKOUT MOUSE; LIPID PEROXIDATION; METABOLISM; MOTOR ACTIVITY; PATHOLOGY;

3T3-L1 CELLS; ADIPOSE TISSUE, BROWN; ANIMALS; BIPHENYL COMPOUNDS; CARBAMATES; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; DIGLYCERIDES; ENERGY METABOLISM; FEMALE; HEK293 CELLS; HUMANS; LIPID PEROXIDATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOACYLGLYCEROL LIPASES; MOTOR ACTIVITY; OBESITY; PPAR ALPHA; PPAR GAMMA; THERMOGENESIS; UNCOUPLING PROTEIN 1;

EID: 84961221399     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.02.076     Document Type: Article

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