Tim-3 enhances FcεRI-proximal signaling to modulate mast cell activation

Journal of Experimental Medicine

Volumn 212, Issue 13, 2015, Pages 2289-2304

  Phong, Binh L ^a,b   Avery, Lyndsay ^a,b   Sumpter, Tina L ^a   Gorman, Jacob V ^c   Watkins, Simon C ^a   Colgan, John D ^c   Kane, Lawrence P ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BAT3 PROTEIN; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; FC EPSILON RI; IMMUNOGLOBULIN E RECEPTOR; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; PROTEIN KINASE LYN; T CELL IMMUNOGLOBULIN AND MUCIN DOMAIN PROTEIN 3; UNCLASSIFIED DRUG; ANTIBODY; ANTIGEN; BAG6 PROTEIN, MOUSE; CARCINOEMBRYONIC ANTIGEN; CEACAM1 PROTEIN, MOUSE; CHAPERONE; CROSS LINKING REAGENT; CYTOKINE; HAVCR2 PROTEIN, MOUSE; HEPATITIS A VIRUS CELLULAR RECEPTOR 2; IMMUNOGLOBULIN E; INTERLEUKIN 6; LYN PROTEIN-TYROSINE KINASE; NR4A1 PROTEIN, MOUSE; NUCLEAR PROTEIN; NUCLEAR RECEPTOR NUR77; PHOSPHOLIPASE C GAMMA; PHOSPHOTYROSINE; PROTEIN KINASE SYK; PROTEIN S6; PROTEIN SUBUNIT; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE; SYK PROTEIN, MOUSE; TUMOR NECROSIS FACTOR; VIRUS RECEPTOR;

ANTIGENIC MODULATION; ARTICLE; CELL ACTIVATION; CYTOKINE PRODUCTION; MAST CELL; MAST CELL DEGRANULATION; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; BONE MARROW CELL; C57BL MOUSE; CHEMISTRY; CYTOLOGY; DEGRANULATION; DRUG EFFECTS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; PHOSPHORYLATION; PROTEIN SUBUNIT; TRANSCRIPTION INITIATION;

ANIMALS; ANTIBODIES; ANTIGENS; BONE MARROW CELLS; CARCINOEMBRYONIC ANTIGEN; CELL DEGRANULATION; CROSS-LINKING REAGENTS; CYTOKINES; HEPATITIS A VIRUS CELLULAR RECEPTOR 2; IMMUNOGLOBULIN E; INTERLEUKIN-6; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAST CELLS; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR CHAPERONES; NUCLEAR PROTEINS; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 1; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN SUBUNITS; PROTEIN-TYROSINE KINASES; RECEPTORS, IGE; RECEPTORS, VIRUS; RIBOSOMAL PROTEIN S6; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; SYK KINASE; TRANSCRIPTIONAL ACTIVATION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84961210191     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20150388     Document Type: Article

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