Optimal aggregation of FcεRI with a structurally defined trivalent ligand overrides negative regulation driven by phosphatases

ACS Chemical Biology

Volumn 9, Issue 7, 2014, Pages 1508-1519

  Mahajan, Avanika ^a   Barua, Dipak ^b,c   Cutler, Patrick ^a   Lidke, Diane S ^a   Espinoza, Flor A ^a   Pehlke, Carolyn ^a   Grattan, Rachel ^a   Kawakami, Yuko ^d   Tung, Chang Shung ^b   Bradbury, Andrew R M ^e   Hlavacek, William S ^b,c   Wilson, Bridget S ^a  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^b LOS ALAMOS NATIONAL LABORATORY   (United States)

^c CENTER FOR NONLINEAR STUDIES   (United States)

^d LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^e LOS ALAMOS NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DINITROPHENOL; DF 3; FC EPSILON RECEPTOR I; FC RECEPTOR; LIGAND; PROTEIN TYROSINE PHOSPHATASE SHP 1; PROTEIN TYROSINE PHOSPHATASE SHP 2; UNCLASSIFIED DRUG; ANTIGEN; FCEPSILONRI PROTEIN, RAT; FIBRITIN PROTEIN, ENTEROBACTERIA PHAGE T4; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E RECEPTOR; PEPTIDE; PHOSPHATASE; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; BACTERIOPHAGE T4; CAPPING PHENOMENON; CELL MEMBRANE; CROSS LINKING; ENDOCYTOSIS; ENZYME LOCALIZATION; FLUORESCENCE IMAGING; IMMUNOELECTRON MICROSCOPY; MAST CELL DEGRANULATION; MOLECULAR MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SIGNAL TRANSDUCTION; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; DEGRANULATION; HUMAN; IMMUNOLOGY; MAST CELL; RAT;

ANIMALS; ANTIGENS; CELL DEGRANULATION; HUMANS; IMMUNOGLOBULIN E; LIGANDS; MAST CELLS; MODELS, MOLECULAR; PEPTIDES; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; RATS; RECEPTORS, IGE; SIGNAL TRANSDUCTION; VIRAL PROTEINS;

EID: 84904536350     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb500134t     Document Type: Article

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