A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome

Nature

Volumn 510, Issue 7504, 2014, Pages 293-297

  Simon, Aline C ^a   Zhou, Jin C ^b   Perera, Rajika L ^a,e   Van Deursen, Frederick ^c   Evrin, Cecile ^d   Ivanova, Marina E ^a,b   Kilkenny, Mairi L ^a   Renault, Ludovic ^b   Kjaer, Svend ^b   Matak Vinkovi, Dijana ^a   Labib, Karim ^d   Costa, Alessandro ^b   Pellegrini, Luca ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d UNIVERSITY OF DUNDEE   (United Kingdom)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CDC45 MCM GINS DNA HELICASE; DNA DIRECTED DNA POLYMERASE ALPHA; DNA HELICASE; PEPTIDES AND PROTEINS; PROTEIN CTF4; UNCLASSIFIED DRUG;

CATALYSIS; DNA; EUKARYOTE; GENOMICS; POLYMERASE CHAIN REACTION;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; ELECTRON MICROSCOPY; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REPLISOME; X RAY CRYSTALLOGRAPHY;

ESCHERICHIA COLI; EUKARYOTA;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CATALYTIC DOMAIN; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DNA HELICASES; DNA POLYMERASE I; DNA REPLICATION; DNA-BINDING PROTEINS; DNA-DIRECTED DNA POLYMERASE; MICROSCOPY, ELECTRON; MINICHROMOSOME MAINTENANCE PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN SUBUNITS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84902304914     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13234     Document Type: Article

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