The sweetness and bitterness of childhood: Insights from basic research on taste preferences

Physiology and Behavior

Volumn 152, Issue , 2015, Pages 502-507

  Mennella, Julie A ^a   Bobowski, Nuala K ^a  

^a MONELL CHEMICAL SENSES CENTER   (United States)

Author keywords

Children; Diet; Genetic variation; Learning; Taste

Indexed keywords

SUCROSE;

AGE; ARTICLE; BASIC RESEARCH; BITTER TASTE; CHILDHOOD; FOOD PREFERENCE; GENOTYPE; GENOTYPE PHENOTYPE CORRELATION; HUMAN; LIFESPAN; PERCEPTION; PLEASURE; PRIORITY JOURNAL; SUGAR INTAKE; SWEETNESS; TASTE BUD; TASTE PREFERENCE; ANIMAL; CHILD; CHILD DEVELOPMENT; PHYSIOLOGY; TASTE;

ANIMALS; CHILD; CHILD DEVELOPMENT; FOOD PREFERENCES; HUMANS; TASTE PERCEPTION;

EID: 84961190691     PISSN: 00319384     EISSN: 1873507X     Source Type: Journal    
DOI: 10.1016/j.physbeh.2015.05.015     Document Type: Article

References (91)

1. Woloson W.A. Refined Tastes: Sugar, Confectionery, and Consumers in Nineteenth-Century America 2002, The Johns Hopkins University Press, Baltimore, Maryland.
2. Oxford Encyclopedia of Food and Drink in America 2004, Oxford University Press, New York, NY. A.F. Smith (Ed.).
3. Forestell CA, Mennella JA. The ontogeny of taste perception and preference throughout childhood. In Handbook of Olfaction and Gustation. 3rd Edition. Edited by Doty R.L. New York: Marcel Dekker; 2015.
4. Steiner J.E., Glaser D., Hawilo M.E., Berridge K.C. Comparative expression of hedonic impact: affective reactions to taste by human infants and other primates. Neurosci. Biobehav. Rev. 2001, 25:53-74.
5. Glanz K., Basil M., Maibach E., Goldberg J., Snyder D. Why Americans eat what they do: taste, nutrition, cost, convenience, and weight control concerns as influences on food consumption. J. Am. Diet. Assoc. 1998, 98:1118-1126.
6. Berridge K.C. Pleasures of the brain. Brain Cogn. 2003, 52:106-128.
7. Small D.M. Flavor is in the brain. Physiol. Behav. 2012, 107:540-552.
8. Small D.M. Individual differences in the neurophysiology of reward and the obesity epidemic. Int. J. Obes. 2009, 33(Suppl 2):S44-S48.
9. Nelson G., Hoon M.A., Chandrashekar J., Zhang Y., Ryba N.J., Zuker C.S. Mammalian sweet taste receptors. Cell 2001, 106:381-390.
10. Maone T.R., Mattes R.D., Bernbaum J.C., Beauchamp G.K. A new method for delivering a taste without fluids to preterm and term infants. Dev. Psychobiol. 1990, 13:179-191.
11. Nowlis G.H., Kessen W. Human newborns differentiate differing concentrations of sucrose and glucose. Science 1976, 191:865-866.
12. Desor JA, Maller O, Turner RE. Preference for sweet in humans: infants, children and adults. In Taste and Development: The Genesis of Sweet Preference. Edited by Weiffenbach J.M. Washington, DC: US Government Printing Office; 1977.
13. Rosenstein D., Oster H. Differential facial responses to four basic tastes in newborns. Child Dev. 1988, 59:1555-1568.
14. Steiner JE. Facial expressions of the neonate infant indicating the hedonics of food-related chemical stimuli. In Taste and Development: The Genesis of Sweet Preference. Edited by Weiffenbach J.M. Washington, DC: U.S. Government Printing Office; 1977.
15. Fox N.A., Davidson R.J. Taste-elicited changes in facial signs of emotion and the asymmetry of brain electrical activity in human newborns. Neuropsychologia 1986, 24:417-422.
16. Ashmead D.H., Reilly B.M., Lipsitt L.P. Neonates' heart rate, sucking rhythm, and sucking amplitude as a function of the sweet taste. J. Exp. Child Psychol. 1980, 29:264-281.
17. Blass E.M., Watt L.B. Suckling- and sucrose-induced analgesia in human newborns. Pain 1999, 83:611-623.
18. Blass E.M., Hoffmeyer L.B. Sucrose as an analgesic for newborn infants. Pediatrics 1991, 87:215-218.
19. Barr R.G., Pantel M.S., Young S.N., Wright J.H., Hendricks L.A., Gravel R. The response of crying newborns to sucrose: is it a "sweetness" effect?. Physiol. Behav. 1999, 66:409-417.
20. Ramenghi L.A., Evans D.J., Levene M.I. "Sucrose analgesia": absorptive mechanism or taste perception?. Arch. Dis. Child. Fetal Neonatal Ed. 1999, 80:F146-F147.
21. Stevens B., Yamada J., Ohlsson A. Sucrose for analgesia in newborn infants undergoing painful procedures. Cochrane Database Syst. Rev. 2010, CD001069.
22. Miller A., Barr R.G., Young S.N. The cold pressor test in children: methodological aspects and the analgesic effect of intraoral sucrose. Pain 1994, 56:175-183.
23. Mennella J.A., Pepino M.Y., Lehmann-Castor S.M., Yourshaw L.M. Sweet preferences and analgesia during childhood: effects of family history of alcoholism and depression. Addiction 2010, 105:666-675.
24. Pepino M.Y., Mennella J.A. Sucrose-induced analgesia is related to sweet preferences in children but not adults. Pain 2005, 119:210-218.
25. Cowart BJ, Beauchamp GK. Early development of taste perception. In Psychological Basis of Sensory Evaluation. Edited by R. McBride, H. MacFie. 1990: 1-7. London, England.
26. Coldwell S.E., Mennella J.A., Duffy V.B., Pelchat M.L., Griffith J.W., Smutzer G., et al. Gustation assessment using the NIH toolbox. Neurology 2013, 80:S20-S24.
27. Mennella J.A., Lukasewycz L.D., Griffith J.W., Beauchamp G.K. Evaluation of the Monell Forced-Choice, Paired-Comparison Tracking Procedure for determining sweet taste preferences across the lifespan. Chem Senses 2011.
28. Desor J.A., Beauchamp G.K. Longitudinal changes in sweet preferences in humans. Physiol. Behav. 1987, 39:639-641.
29. Dhurandhar N.V., Schoeller D., Brown A.W., Heymsfield S.B., Thomas D., Sorensen T.I., et al. Energy balance measurement: when something is not better than nothing. Int J Obes (Lond) 2014, [Epub ahead of print]. 10.1038/ijo.2014.199.
30. U.S. Department of Agriculture ARS, Beltsville Human Nutrition Research Center, Food Surveys Research Group (Beltsville, MD) and U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics (Hyattsville, MD). What we eat in America, NHANES 2001-2002, Dietary Interview - Total Nutrients Intakes Accessed on: January 7, 2015. []. http://www.ars.usda.gov/SP2UserFiles/Place/80400530/pdf/0102/Table_1_BIA.pdf.
31. U.S. Department of Agriculture ARS, Beltsville Human Nutrition Research Center, Food Surveys Research Group (Beltsville, MD) and U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics (Hyattsville, MD). What we eat in America, NHANES 2003-2004, Dietary Interview - Total Nutrients Intakes. Accessed on: January 7, 2015. []. http://www.ars.usda.gov/SP2UserFiles/Place/80400530/pdf/0304/Table_1_NIF.pdf.
32. U.S. Department of Agriculture ARS, Beltsville Human Nutrition Research Center, Food Surveys Research Group (Beltsville, MD) and U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics (Hyattsville, MD). What we eat in America, NHANES 2005-2006, Dietary Interview - Total Nutrients Intakes.
33. U.S. Department of Agriculture ARS, Beltsville Human Nutrition Research Center, Food Surveys Research Group (Beltsville, MD) and U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics (Hyattsville, MD). What we eat in America, NHANES 2007-2008, Dietary Interview - Total Nutrients Intakes Accessed on: January 7, 2015. []. http://www.ars.usda.gov/SP2UserFiles/Place/80400530/pdf/0708/Table_1_NIN_GEN_07.pdf.
34. U.S. Department of Agriculture ARS, Beltsville Human Nutrition Research Center, Food Surveys Research Group (Beltsville, MD) and U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics (Hyattsville, MD). What we eat in America, NHANES 2009-2010, Dietary Interview - Total Nutrients Intakes Accessed on: January 7, 2015. []. http://www.ars.usda.gov/SP2UserFiles/Place/80400530/pdf/0910/Table_1_NIN_GEN_09.pdf.
35. U.S. Department of Agriculture ARS, Beltsville Human Nutrition Research Center, Food Surveys Research Group (Beltsville, MD) and U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics (Hyattsville, MD). What we eat in America, NHANES 2011-2012, Dietary Interview - Total Nutrients Intakes Accessed on: January 7, 2015. []. http://www.ars.usda.gov/SP2UserFiles/Place/80400530/pdf/1112/Table_1_NIN_GEN_11.pdf.
36. Food and Agriculture Organization of the United Nations. Food balance sheets Accessed on: January 7, 2015. []. http://faostat3.fao.org/download/FB/*/E.
37. Slining M.M., Popkin B.M. Trends in intakes and sources of solid fats and added sugars among U.S. children and adolescents: 1994-2010. Pediatr Obes 2013, 8:307-324.
38. Bertino M., Wehmer F. Dietary influences on the development of sucrose acceptability in rats. Dev. Psychobiol. 1981, 14:19-28.
39. Drewnowski A. Sensory control of energy density at different life stages. Proc Nutr Soc 2000, 59:239-244.
40. Coldwell S.E., Oswald T.K., Reed D.R. A marker of growth differs between adolescents with high vs. low sugar preference. Physiol. Behav. 2009, 96:574-580.
41. Yang L., Grey V. Pediatric reference intervals for bone markers. Clin. Biochem. 2006, 39:561-568.
42. Liem D.G., Mennella J.A. Sweet and sour preferences during childhood: role of early experiences. Dev. Psychobiol. 2002, 41:388-395.
43. Mennella J.A., Pepino M.Y., Reed D.R. Genetic and environmental determinants of bitter perception and sweet preferences. Pediatrics 2005, 115:e216-e222.
44. Mennella J.A., Finkbeiner S., Reed D.R. The proof is in the pudding: children prefer lower fat but higher sugar than do mothers. Int. J. Obes. 2012, 36:1285-1291.
45. Mennella J.A., Reed D.R., Mathew P.S., Roberts K.M., Mansfield C.J. "A spoonful of sugar helps the medicine go down": bitter masking by sucrose among children and adults. Chem. Senses 2014, 40:17-25.
46. Mattes R.D., Popkin B.M. Nonnutritive sweetener consumption in humans: effects on appetite and food intake and their putative mechanisms. Am J Clin Nutr 2009, 89:1-14.
47. Sullivan S.A., Birch L.L. Pass the sugar, pass, the salt: experience dictates preference. Dev. Psychol. 1990, 26:546-551.
48. Beauchamp G.K., Moran M. Acceptance of sweet and salty tastes in 2-year-old children. Appetite 1984, 5:291-305.
49. Pepino M.Y., Mennella J.A. Factors contributing to individual differences in sucrose preference. Chem. Senses 2005, 30(Suppl 1):i319-i320.
50. Simmen B., Hladik C.M. Sweet and bitter taste discrimination in primates: scaling effects across species. Folia Primatol (Basel) 1998, 69:129-138.
51. Beauchamp G.K., Cowart B.J. Congenital and experiential factors in the development of human flavor preferences. Appetite 1985, 6:357-372.
52. Sclafani A. Oral and postoral determinants of food reward. Physiol. Behav. 2004, 81:773-779.
53. Mennella J.A., Nicklaus S., Jagolino A.L., Yourshaw L.M. Variety is the spice of life: strategies for promoting fruit and vegetable acceptance during infancy. Physiol. Behav. 2008, 94:29-38.
54. Gerrish C.J., Mennella J.A. Flavor variety enhances food acceptance in formula-fed infants. Am J Clin Nutr 2001, 73:1080-1085.
55. Forestell C.A., Mennella J.A. Early determinants of fruit and vegetable acceptance. Pediatrics 2007, 120:1247-1254.
56. Rozin P. The acquisition of food habits and preferences. In Behavioral Health: A Handbook of Health Enhancement and Disease Prevention. Edited by Mattarazzo H.D., Weiss S.M., Herd J.A., Miller N.E., Weiss S.M. New York, New York: John Wiley and Sons; 1984: 590-607.
57. Rozin P., Vollmecke T.A. Food likes and dislikes. Annu. Rev. Nutr. 1986, 6:433-456.
58. Reed D.R., Tanaka T., McDaniel A.H. Diverse tastes: genetics of sweet and bitter perception. Physiol. Behav. 2006, 88:215-226.
59. Adler E., Hoon M.A., Mueller K.L., Chandrashekar J., Ryba N.J., Zuker C.S. A novel family of mammalian taste receptors. Cell 2000, 100:693-702.
60. Chandrashekar J., Mueller K.L., Hoon M.A., Adler E., Feng L., Guo W., et al. T2Rs function as bitter taste receptors. Cell 2000, 100:703-711.
61. Meyerhof W., Batram C., Kuhn C., Brockhoff A., Chudoba E., Bufe B., et al. The molecular receptive ranges of human TAS2R bitter taste receptors. Chem. Senses 2010, 35:157-170.
62. Lund E. Non-nutritive bioactive constituents of plants: dietary sources and health benefits of glucosinolates. Int. J. Vitam. Nutr. Res. 2003, 73:135-143.
63. Bartoshuk L.M., Duffy V.B., Reed D., Williams A. Supertasting, earaches and head injury: genetics and pathology alter our taste worlds. Neurosci Biobehav R 1996, 20:79-87.
64. Duffy V.B. Variation in oral sensation: implications for diet and health. Curr. Opin. Gastroenterol. 2007, 23:171-177.
65. Sandell M.A., Breslin P.A. Variability in a taste-receptor gene determines whether we taste toxins in food. Curr. Biol. 2006, 16:R792-R794.
66. Bufe B., Breslin P.A., Kuhn C., Reed D.R., Tharp C.D., Slack J.P., et al. The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception. Curr. Biol. 2005, 15:322-327.
67. Kim U., Jorgenson E., Coon H., Leppert M., Risch N., Drayna D. Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide. Science 2003, 299:1221-1225.
68. Mennella J.A., Pepino M.Y., Duke F.F., Reed D.R. Age modifies the genotype-phenotype relationship for the bitter receptor TAS2R38. BMC Genet. 2010, 11:60.
69. Lipchock S.V., Mennella J.A., Spielman A.I., Reed D.R. Human bitter perception correlates with bitter receptor messenger RNA expression in taste cells. Am J Clin Nutr 2013, 98:1136-1143.
70. Kajuira H., Cowart B.J., Beauchamp G.K. Early developmental change in bitter taste responses in human infants. Dev. Psychobiol. 1992, 25:375-386.
71. Cowart B.J., Yokomukai Y., Beauchamp G.K. Bitter taste in aging: compound-specific decline in sensitivity. Physiol. Behav. 1994, 56:1237-1241.
72. Duffy V.B., Hayes J.E., Davidson A.C., Kidd J.R., Kidd K.K., Bartoshuk L.M. Vegetable intake in college-aged adults is explained by oral sensory phenotypes and TAS2R38 genotype. Chemosens. Percept. 2010, 3:137-148.
73. Lipchock S.V., Reed D.R., Mennella J.A. Relationship between bitter-taste receptor genotype and solid medication formulation usage among young children: a retrospective analysis. Clin. Ther. 2012, 34:728-733.
74. Fischer R., Griffin F. Pharmacogenetic aspects of gustation. Arzneimittelforschung 1964, 14:673-686.
75. Breslin P.A., Beauchamp G.K. Suppression of bitterness by sodium: variation among bitter taste stimuli. Chem. Senses 1995, 20:609-623.
76. Keast R.S., Canty T.M., Breslin P.A. The influence of sodium salts on binary mixtures of bitter-tasting compounds. Chem. Senses 2004, 29:431-439.
77. Mennella J.A., Reed D.R., Roberts K.M., Mathew P.S., Mansfield C.J. Age-related differences in bitter taste and efficacy of bitter blockers. PLoS One 2014, 9. e103107.
78. Mennella J.A., Pepino M.Y., Beauchamp G.K. Modification of bitter taste in children. Dev. Psychobiol. 2003, 43:120-127.
79. Kroeze J.H., Bartoshuk L.M. Bitterness suppression as revealed by split-tongue taste stimulation in humans. Physiol. Behav. 1985, 35:779-783.
80. Childs E., de Wit H. Subjective, behavioral, and physiological effects of acute caffeine in light, nondependent caffeine users. Psychopharmacology 2006, 185:514-523.
81. Holdstock L., King A.C., de Wit H. Subjective and objective responses to ethanol in moderate/heavy and light social drinkers. Alcohol. Clin. Exp. Res. 2000, 24:789-794.
82. Stevens JC. Detection of tastes in mixture with other tastes: issues of masking and aging. Chem. Senses 1996; 21:211-21.
83. Temple J.L. Caffeine use in children: what we know, what we have left to learn, and why we should worry. Neurosci Biobehav R 2009, 33:793-806.
84. Branum A.M., Rossen L.M., Schoendorf K.C. Trends in caffeine intake among U.S. children and adolescents. Pediatrics 2014, 133:386-393.
85. Glendinning J.I. Is the bitter rejection response always adaptive?. Physiol. Behav. 1994, 56:1217-1227.
86. Cogswell M.E., Gunn J.P., Yuan K., Park S., Merritt R. Sodium and sugar in complementary infant and toddler foods sold in the United States. Pediatrics 2015, 135.
87. Baker S.S., Baker R.D. Early exposure to dietary sugar and salt. Pediatrics 2015, 135.
88. Kissileff H.R., Ladenheim E. The evolution of the Society for the Study of Ingestive Behavior (SSIB). Physiol. Behav. 2013, 121:3-9.
89. Mennella J.A., Spector A.C., Reed D.R., Coldwell S.E. The bad taste of medicines: overview of basic research on bitter taste. Clin. Ther. 2013, 35:1225-1246.
90. Giacoia G.P., Taylor-Zapata P., Zajicek A. Eunice Kennedy Shriver National Institute of Child Health and Human Development Pediatrics Formulation Initiative: Proceedings from the Second Workshop on Pediatric Formulations. Clin. Ther. 2012, 34:S1-10.
91. Mennella J.A. Ontogeny of taste preferences: basic biology and implications for health. Am J Clin Nutr 2014, 99:704S-711S.