메뉴 건너뛰기




Volumn 11, Issue 3, 2016, Pages

Depression, stressful life events, and the impact of variation in the serotonin transporter: Findings from the national longitudinal study of adolescent to adult health (Add Health)

Author keywords

[No Author keywords available]

Indexed keywords

SEROTONIN TRANSPORTER; SLC6A4 PROTEIN, HUMAN;

EID: 84961185399     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0148373     Document Type: Article
Times cited : (28)

References (52)
  • 1
    • 33845338724 scopus 로고    scopus 로고
    • Projections of global mortality and burden of disease from 2002 to 2030
    • Matthers CD, Loncar D. [2006] Projections of global mortality and burden of disease from 2002 to 2030. PloS Medicine 3[11]: e442.
    • (2006) PloS Medicine , vol.3 , Issue.11 , pp. e442
    • Matthers, C.D.1    Loncar, D.2
  • 2
    • 0042160065 scopus 로고    scopus 로고
    • Global burden of depression: The intersection of culture and medicine
    • Scott J, Dickey B. [2003] Global burden of depression: The intersection of culture and medicine. British Journal of Psychiatry 183: 93-94.
    • (2003) British Journal of Psychiatry , vol.183 , pp. 93-94
    • Scott, J.1    Dickey, B.2
  • 3
    • 73649143114 scopus 로고    scopus 로고
    • Structure and stress: Trajectories of depressive symptoms across adolescence and young adulthood
    • Adkins DE, Wang V, Dupre ME, van den Oord EJCD, Elder GH. [2009] Structure and stress: Trajectories of depressive symptoms across adolescence and young adulthood. Social Forces 88: 31-60.
    • (2009) Social Forces , vol.88 , pp. 31-60
    • Adkins, D.E.1    Wang, V.2    Dupre, M.E.3    Van Den Oord, E.J.C.D.4    Elder, G.H.5
  • 4
    • 77958151479 scopus 로고    scopus 로고
    • The epidemiology of major depression and ethnicity in the United States
    • Gonzalez HM, Tarraf W, Whitfield KE, Vega WA. [2010] The epidemiology of major depression and ethnicity in the United States. Journal of Psychiatric Research 44: 1043-1051. doi: 10.1016/j.jpsychires. 2010.03.017
    • (2011) Journal of Psychiatric Research , vol.44 , pp. 1043-1051
    • Gonzalez, H.M.1    Tarraf, W.2    Whitfield, K.E.3    Vega, W.A.4
  • 5
    • 0014118642 scopus 로고
    • The social readjustment rating scale
    • Holmes TH, Rahe RH. [1967] The social readjustment rating scale. J Psychosom Res 11: 213-218.
    • (1967) J Psychosom Res , vol.11 , pp. 213-218
    • Holmes, T.H.1    Rahe, R.H.2
  • 7
    • 0032434408 scopus 로고    scopus 로고
    • Stressful life events and major depression: Risk period, long-Term contextual threat, and diagnostic specificity
    • Kendler KS, Karkowski LM, Prescott CA. [1998] Stressful life events and major depression: risk period, long-Term contextual threat, and diagnostic specificity. J Nerv Ment Dis 186: 661-669.
    • (1998) J Nerv Ment Dis , vol.186 , pp. 661-669
    • Kendler, K.S.1    Karkowski, L.M.2    Prescott, C.A.3
  • 8
    • 0030638601 scopus 로고    scopus 로고
    • The effects of stressful life events on depression
    • Kessler RC. [1997] The effects of stressful life events on depression. Ann Rev Psychol 48:191-214.
    • (1997) Ann Rev Psychol , vol.48 , pp. 191-214
    • Kessler, R.C.1
  • 9
    • 77951854270 scopus 로고    scopus 로고
    • Genetic sensitivity to the environment: The case of the serotonin transporter gene and its implications for studying complex diseases and traits
    • Caspi A, Hariri AR, Holmes A, Uher R, Moffitt TE. [2010] Genetic sensitivity to the environment: The case of the serotonin transporter gene and its implications for studying complex diseases and traits. American Journal of Psychiatry. 167: 509-527. doi: 10.1176/appi.ajp.2010.09101452
    • (2011) American Journal of Psychiatry , vol.167 , pp. 509-527
    • Caspi, A.1    Hariri, A.R.2    Holmes, A.3    Uher, R.4    Moffitt, T.E.5
  • 10
    • 84859215167 scopus 로고    scopus 로고
    • Serotonergic transcriptional networks and potential importance to mental health
    • Deneris E, Wyler SC. [2012] Serotonergic transcriptional networks and potential importance to mental health. Nature Neuroscience 15: 519-527. doi: 10.1038/nn.3039
    • (2012) Nature Neuroscience , vol.15 , pp. 519-527
    • Deneris, E.1    Wyler, S.C.2
  • 11
    • 33748324559 scopus 로고    scopus 로고
    • Stress-related negative affectivity and genetically altered serotonin transporter function
    • Jacobs N, Kenis G, Peeters F, Derom C, Vlietinck R, van Os J. [2006] Stress-related negative affectivity and genetically altered serotonin transporter function. Arch Gen Psychiatry 63: 989-996.
    • (2006) Arch Gen Psychiatry , vol.63 , pp. 989-996
    • Jacobs, N.1    Kenis, G.2    Peeters, F.3    Derom, C.4    Vlietinck, R.5    Van Os, J.6
  • 12
    • 68049126142 scopus 로고    scopus 로고
    • Accurate, large-scale genotyping of 5HTTLPR and flanking single nucleotide polymorphisms in an association study of depression, anxiety, and personality measures
    • Wray NR, James MR, Gordon SD, Dumenil T, Ryan L, Coventry WL, et al. [2009] Accurate, large-scale genotyping of 5HTTLPR and flanking single nucleotide polymorphisms in an association study of depression, anxiety, and personality measures. Biol Psychiatry 66: 468-476. doi: 10.1016/j.biopsych. 2009.04.030
    • (2009) Biol Psychiatry , vol.66 , pp. 468-476
    • Wray, N.R.1    James, M.R.2    Gordon, S.D.3    Dumenil, T.4    Ryan, L.5    Coventry, W.L.6
  • 13
    • 79955534063 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphism implicates reduced orbito-frontal cortex in obsessive-compulsive disorder
    • Atmaca M, Onalan E, Yildirim H, Uyce H, Koc M, Korkmaz S, et al. [2011] Serotonin transporter gene polymorphism implicates reduced orbito-frontal cortex in obsessive-compulsive disorder. J Anxiety Disord 25: 680-685.
    • (2011) J Anxiety Disord , vol.25 , pp. 680-685
    • Atmaca, M.1    Onalan, E.2    Yildirim, H.3    Uyce, H.4    Koc, M.5    Korkmaz, S.6
  • 15
    • 0006463359 scopus 로고    scopus 로고
    • Association of anxietyrelated traits with a polymorphism in the serotonin transporter gene regulatory region
    • Lesch KP, Bengel D, Heils A, Sabol SZ, Greeberg BD, Petri S, et al. [1996] Association of anxietyrelated traits with a polymorphism in the serotonin transporter gene regulatory region. Science 274: 1527-1531.
    • (1996) Science , vol.274 , pp. 1527-1531
    • Lesch, K.P.1    Bengel, D.2    Heils, A.3    Sabol, S.Z.4    Greeberg, B.D.5    Petri, S.6
  • 16
    • 0037624040 scopus 로고    scopus 로고
    • Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene
    • Caspi A, Sugden K, Moffitt TE, Taylor A, Craig IW, Harrington H, et al. [2003] Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301: 386-389.
    • (2003) Science , vol.301 , pp. 386-389
    • Caspi, A.1    Sugden, K.2    Moffitt, T.E.3    Taylor, A.4    Craig, I.W.5    Harrington, H.6
  • 18
    • 13444280555 scopus 로고    scopus 로고
    • The relationship between stressful life events, the serotonin transporter (5-HTTLPR) genotype and major depression
    • Gillespie NA, Whitfield JB, Williams B, Heath AC, Martin NG. [2005] The relationship between stressful life events, the serotonin transporter (5-HTTLPR) genotype and major depression. Psychol Med 35: 101-111.
    • (2005) Psychol Med , vol.35 , pp. 101-111
    • Gillespie, N.A.1    Whitfield, J.B.2    Williams, B.3    Heath, A.C.4    Martin, N.G.5
  • 19
    • 18244389951 scopus 로고    scopus 로고
    • The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression
    • Kendler KS, Kuhn JW, Vittum J, Prescott CA, Riley B. [2005] The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression. Arch Gen Psychiatry. 62: 529-535.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 529-535
    • Kendler, K.S.1    Kuhn, J.W.2    Vittum, J.3    Prescott, C.A.4    Riley, B.5
  • 20
    • 58149308050 scopus 로고    scopus 로고
    • Gene x environment interactions at the serotonin transporter locus
    • Munafo MR, Durrant C, Lewis G, Flint J. [2009] Gene x environment interactions at the serotonin transporter locus. Biol Psychiatry 65: 211-219. doi: 10.1016/j.biopsych.2008.06.009
    • (2009) Biol Psychiatry , vol.65 , pp. 211-219
    • Munafo, M.R.1    Durrant, C.2    Lewis, G.3    Flint, J.4
  • 21
    • 67649206975 scopus 로고    scopus 로고
    • Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression
    • Risch N, Herrell R, Lehner T, Liang KY, Eaves L, Hoh J, et al. [2009] Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression. JAMA. 301[23]: 2462-2471. doi: 10.1001/jama.2009.878
    • (2009) JAMA , vol.301 , Issue.23 , pp. 2462-2471
    • Risch, N.1    Herrell, R.2    Lehner, T.3    Liang, K.Y.4    Eaves, L.5    Hoh, J.6
  • 22
    • 79952033418 scopus 로고    scopus 로고
    • The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-Analysis revisited
    • Karg K, Burmeister M, Shedden K, Sen S. [2011] The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-Analysis revisited. Arch Gen Psychiatry 68: 444-454. doi: 10. 1001/archgenpsychiatry.2010.189
    • (2011) Arch Gen Psychiatry , vol.68 , pp. 444-454
    • Karg, K.1    Burmeister, M.2    Shedden, K.3    Sen, S.4
  • 23
    • 72949099687 scopus 로고    scopus 로고
    • The moderation by the serotonin transporter gene of environmental adversity in the etiology of depression: 2009 update
    • Uher R, McGuffin P. [2010] The moderation by the serotonin transporter gene of environmental adversity in the etiology of depression: 2009 update. Mol Psychiatry 15: 18-22. doi: 10.1038/mp.2009.123
    • (2011) Mol Psychiatry , vol.15 , pp. 18-22
    • Uher, R.1    McGuffin, P.2
  • 24
    • 84859840402 scopus 로고    scopus 로고
    • An interaction between perceived stress and 5HTTLPR genotype in the prediction of stable depressive symptomatology
    • Beaver KM, Vaughn MG, Wright JP, Delisi M. [2012] An interaction between perceived stress and 5HTTLPR genotype in the prediction of stable depressive symptomatology. Am J Orthopsychiatry 82 [2]: 260-266.
    • (2012) Am J Orthopsychiatry , vol.82 , Issue.2 , pp. 260-266
    • Beaver, K.M.1    Vaughn, M.G.2    Wright, J.P.3    Delisi, M.4
  • 25
    • 80051953349 scopus 로고    scopus 로고
    • A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry
    • Duncan LE, Keller MC. [2011] A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry. Am J Psychiatry 168: 1041-1049. doi: 10.1176/appi.ajp.2011. 11020191
    • (2011) Am J Psychiatry , vol.168 , pp. 1041-1049
    • Duncan, L.E.1    Keller, M.C.2
  • 26
  • 27
    • 34548697514 scopus 로고    scopus 로고
    • Relationship of 5-HTTLPR genotypes and depression risk in the presence of trauma in a female twin sample
    • Chorbov VM, Lobos EA, Todorov AA, Health AC, Botteron KN, Todd RD. [2007] Relationship of 5-HTTLPR genotypes and depression risk in the presence of trauma in a female twin sample. Am J Med Genet 144B: 830-833.
    • (2007) Am J Med Genet , vol.144 , pp. 830-833
    • Chorbov, V.M.1    Lobos, E.A.2    Todorov, A.A.3    Health, A.C.4    Botteron, K.N.5    Todd, R.D.6
  • 28
    • 33745556951 scopus 로고    scopus 로고
    • Development of depression: Sex and the interaction between environment and a promoter polymorphism of the serotonin transporter gene
    • Sjoberg RL, Nilsson KW, Nordquist N, Ohrvik J, Leppert J, Lindstrom L, Oreland L. [2006] Development of depression: sex and the interaction between environment and a promoter polymorphism of the serotonin transporter gene. Int J Neuropsychopharamcol 9: 443-449.
    • (2006) Int J Neuropsychopharamcol , vol.9 , pp. 443-449
    • Sjoberg, R.L.1    Nilsson, K.W.2    Nordquist, N.3    Ohrvik, J.4    Leppert, J.5    Lindstrom, L.6    Oreland, L.7
  • 29
    • 13244260769 scopus 로고    scopus 로고
    • Mental and physical distress is modulated by a polymorphism in the 5-HT transporter gene interating with social stressors and chronic disease burden
    • Grabe HJ, Lange M, Wolff B, Volzke H, Lucht M, Freyberger HJ, et al. [2005] Mental and physical distress is modulated by a polymorphism in the 5-HT transporter gene interating with social stressors and chronic disease burden. Mol Psychiatry 10: 220-224.
    • (2005) Mol Psychiatry , vol.10 , pp. 220-224
    • Grabe, H.J.1    Lange, M.2    Wolff, B.3    Volzke, H.4    Lucht, M.5    Freyberger, H.J.6
  • 30
    • 38649105517 scopus 로고    scopus 로고
    • Effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphism (5-HTTLPR
    • Brummett BH, Boyle SH, Siegler IC, Kuhn CM, Ashley-Koch A, Jonassaint CR, et al. [2008] Effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphism (5-HTTLPR). Behav Genet 38: 34-43.
    • (2008) Behav Genet , vol.38 , pp. 34-43
    • Brummett, B.H.1    Boyle, S.H.2    Siegler, I.C.3    Kuhn, C.M.4    Ashley-Koch, A.5    Jonassaint, C.R.6
  • 31
    • 22844449681 scopus 로고    scopus 로고
    • Subthreshold depression is linked to the functional polymorphism of the 5HT transporter gene
    • Gonda X, Juhasz G, Laszik A, Rihmer Z, Bagdy G. [2005] Subthreshold depression is linked to the functional polymorphism of the 5HT transporter gene. J Affect Disord 87: 291-297.
    • (2005) J Affect Disord , vol.87 , pp. 291-297
    • Gonda, X.1    Juhasz, G.2    Laszik, A.3    Rihmer, Z.4    Bagdy, G.5
  • 32
    • 33846205961 scopus 로고    scopus 로고
    • The National Longitudinal Study of Adolescent Health (Add Health) twin data
    • Harris KM, Halpern CT, Smolen A, Haberstick BC. [2006] The National Longitudinal Study of Adolescent Health (Add Health) twin data. Twin Res Hum Genet, 9: 988-997.
    • (2006) Twin Res Hum Genet , vol.9 , pp. 988-997
    • Harris, K.M.1    Halpern, C.T.2    Smolen, A.3    Haberstick, B.C.4
  • 34
    • 84965520932 scopus 로고
    • The CES-D Scale: A self-report depression scale for research in the general population
    • Radloff L. [1977] The CES-D Scale: A self-report depression scale for research in the general population. Appl Psychol Meas 385-401.
    • (1977) Appl Psychol Meas , pp. 385-401
    • Radloff, L.1
  • 37
    • 77949772292 scopus 로고    scopus 로고
    • Gene-environment-wide association studies: Emerging approaches
    • Thomas D. [2010] Gene-environment-wide association studies: Emerging approaches. Nature Rev Genet 11: 259-272. doi: 10.1038/nrg2764
    • (2011) Nature Rev Genet , vol.11 , pp. 259-272
    • Thomas, D.1
  • 38
    • 35348866172 scopus 로고    scopus 로고
    • The contribution of gene-environment interaction to psychopathology
    • Thapar A, Harold G, Rice F, Langley K, O'Donovan M. [2007] The contribution of gene-environment interaction to psychopathology. Dev Psychopath 39: 989-1004.
    • (2007) Dev Psychopath , vol.39 , pp. 989-1004
    • Thapar, A.1    Harold, G.2    Rice, F.3    Langley, K.4    O'Donovan, M.5
  • 39
    • 84993736236 scopus 로고    scopus 로고
    • Measured gene-environment interaction in psychopathology Concepts, research strategies, and implications for research, intervention, and public understanding of genetics
    • Moffitt TE, Caspi A, Rutter M. [2006] Measured gene-environment interaction in psychopathology. Concepts, research strategies, and implications for research, intervention, and public understanding of genetics. Psychol Sci 1: 5-27.
    • (2006) Psychol Sci , vol.1 , pp. 5-27
    • Moffitt, T.E.1    Caspi, A.2    Rutter, M.3
  • 40
    • 55449132547 scopus 로고    scopus 로고
    • Gene-environment interactions in depression research
    • Monroe SM, Reid MW. [2008] Gene-environment interactions in depression research. Psychol Sci 19: 947-956. doi: 10.1111/j.1467-9280.2008.02181.x
    • (2008) Psychol Sci , vol.19 , pp. 947-956
    • Monroe, S.M.1    Reid, M.W.2
  • 41
    • 0030638601 scopus 로고    scopus 로고
    • The effects of stressful life events on depression
    • Kessler RC. [1997] The effects of stressful life events on depression. An Rev Psychol 48: 191-214.
    • (1997) An Rev Psychol , vol.48 , pp. 191-214
    • Kessler, R.C.1
  • 44
    • 2342614896 scopus 로고    scopus 로고
    • Association between serotonin transporter gene promoter polymorphism and suicide: Results of a meta-Analysis
    • Lin PY, Tsai G. [2004] Association between serotonin transporter gene promoter polymorphism and suicide: Results of a meta-Analysis. Biol Psychiatry 55: 1023-1030.
    • (2004) Biol Psychiatry , vol.55 , pp. 1023-1030
    • Lin, P.Y.1    Tsai, G.2
  • 45
    • 0042121277 scopus 로고    scopus 로고
    • A systematic review of asociaiton studies investigating genes coding for serotonin receptors and the serotonin transporter II: Suicidal behavior
    • Anguelova M, Benkelfat C, Turecki G. [2003] A systematic review of asociaiton studies investigating genes coding for serotonin receptors and the serotonin transporter II: Suicidal behavior. Mol Psychiatry 8: 646-653.
    • (2003) Mol Psychiatry , vol.8 , pp. 646-653
    • Anguelova, M.1    Benkelfat, C.2    Turecki, G.3
  • 46
    • 51049089858 scopus 로고    scopus 로고
    • Depression and the serotonin transporter 5-HTTLPR polymorphism: A review and a hypothesis concerning gene-environment interaction
    • Brown GW, Harris TO. [2008] Depression and the serotonin transporter 5-HTTLPR polymorphism: A review and a hypothesis concerning gene-environment interaction. J Affect Disorders 111: 1-12. doi: 10.1016/j.jad.2008.04.009
    • (2008) J Affect Disorders , vol.111 , pp. 1-12
    • Brown, G.W.1    Harris, T.O.2
  • 47
    • 72949099687 scopus 로고    scopus 로고
    • The moderation by the serotonin transporter gene of environmental adversity in the etiology of depression: 2009 update
    • Uher R, McGuffin P. [2010] The moderation by the serotonin transporter gene of environmental adversity in the etiology of depression: 2009 update. Mol Psychiatry 15: 18-22. doi: 10.1038/mp.2009.123
    • (2011) Mol Psychiatry , vol.15 , pp. 18-22
    • Uher, R.1    McGuffin, P.2
  • 49
    • 0027978017 scopus 로고
    • On the remembrance of things past a longitudinal evaluation of the retrospective method
    • Henry B, Moffitt TE, Caspi A, Langley J, Silva PA. [1994] On the "remembrance of things past": A longitudinal evaluation of the retrospective method. Psychol Assess 6: 92-101
    • (1994) Psychol Assess , vol.6 , pp. 92-101
    • Henry, B.1    Moffitt, T.E.2    Caspi, A.3    Langley, J.4    Silva, P.A.5
  • 51
    • 33646072813 scopus 로고    scopus 로고
    • Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder
    • Hu XZ, Lipsky RH, Zhu G, Akhtar LA, Taubman J, Greenberg BD, et al. [2006] Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. Amer J Hum Genet 78: 815-826.
    • (2006) Amer J Hum Genet , vol.78 , pp. 815-826
    • Hu, X.Z.1    Lipsky, R.H.2    Zhu, G.3    Akhtar, L.A.4    Taubman, J.5    Greenberg, B.D.6
  • 52
    • 79953688210 scopus 로고    scopus 로고
    • Human serotonin transporter gene (SLC6A4) variants: Their contributions to understanding pharmacogenomics and other functional GxG and GxE differences in health and disease
    • Murphy ML, Moya PR. [2011] Human serotonin transporter gene (SLC6A4) variants: Their contributions to understanding pharmacogenomics and other functional GxG and GxE differences in health and disease. Curr Opin Pharmacol 11: 3-10.
    • (2011) Curr Opin Pharmacol , vol.11 , pp. 3-10
    • Murphy, M.L.1    Moya, P.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.