Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12

Journal of Experimental Medicine

Volumn 213, Issue 1, 2016, Pages 35-51

  Everts, Bart ^a,d   Tussiwand, Roxane ^a,e   Dreesen, Leentje ^a,f   Fairfax, Keke C ^a,g   Huang, Stanley Ching Cheng ^a   Smith, Amber M ^a   O'Neill, Christina M ^a   Lam, Wing Y ^a   Edelson, Brian T ^a   Urban, Joseph F ^c   Murphy, Kenneth M ^a,b   Pearce, Edward J ^a,f  

^a Department of Pathology and Immunology ^*  (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BELTSVILLE HUMAN NUTRITION RESEARCH CENTER   (United States)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^e UNIVERSITY OF BASEL   (Switzerland)

^f MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^g PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE 1; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR ATF LIKE 3; CD103 ANTIGEN; CD8ALPHA ANTIGEN; GLYCOPROTEIN P 15095; HYDROXYPROLINE; IMMUNOGLOBULIN G1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12P35; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; MESSENGER RNA; PROTEIN; RELM ALPHA PROTEIN; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; YM 1 PROTEIN; ALPHA E INTEGRINS; ALPHA INTEGRIN; LEUKOCYTE ANTIGEN; REPRESSOR PROTEIN; SNFT PROTEIN, MOUSE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL COUNT; CELL MATURATION; CELL MIGRATION; CELLULAR IMMUNODEFICIENCY; CHRONIC DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DISEASE EXACERBATION; EGG PRODUCTION; EOSINOPHIL COUNT; EOSINOPHILIA; EX VIVO STUDY; FECES ANALYSIS; FEMALE; GENE REARRANGEMENT; GRANULOMA; GRANULOMATOUS INFLAMMATION; HELIGMOSOMOIDES POLYGYRUS INFECTION; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOPATHOLOGY; IN VIVO STUDY; INFECTION RESISTANCE; INFLAMMATION; LIVER FIBROSIS; LYMPHOCYTE FUNCTION; MACROPHAGE ACTIVATION; MALE; MOUSE; NATURAL KILLER CELL; NEMATODIASIS; NONHUMAN; PARASITE IMMUNITY; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN DETERMINATION; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; SIGNAL TRANSDUCTION; STEADY STATE; TH2 CELL; UPREGULATION; WOUND HEALING; ANIMAL; BIOSYNTHESIS; CELL MOTION; DEFICIENCY; DISEASE RESISTANCE; GENE EXPRESSION REGULATION; GENETICS; HELMINTH; HELMINTHIASIS; IMMUNITY; IMMUNIZATION; IMMUNOLOGY; IMMUNOMODULATION; KNOCKOUT MOUSE; LIVER CIRRHOSIS; METABOLISM; PATHOLOGY;

ANIMALS; ANTIGENS, CD; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL MOVEMENT; DENDRITIC CELLS; DISEASE RESISTANCE; FEMALE; GENE EXPRESSION REGULATION; HELMINTHIASIS; HELMINTHS; IMMUNITY; IMMUNIZATION; IMMUNOMODULATION; INTEGRIN ALPHA CHAINS; INTERLEUKIN-12; LIVER CIRRHOSIS; MICE; MICE, KNOCKOUT; MODELS, ANIMAL; REPRESSOR PROTEINS; TH2 CELLS; TOLL-LIKE RECEPTORS;

EID: 84961163619     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20150235     Document Type: Article

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