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Volumn 93, Issue , 2016, Pages 18-31

Permissive role of AMPK and autophagy in adiponectin deficiency-accentuated myocardial injury and inflammation in endotoxemia

Author keywords

Adiponectin; Apoptosis; Autophagy; Cardiac function; Endotoxemia; Inflammation

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ADIPONECTIN; BECLIN 1; CASPASE 3; HIGH MOBILITY GROUP B1 PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; I KAPPA B; INTERLEUKIN 1BETA; LC3B PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MARKER; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P62; RAPAMYCIN; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; UNCOORDINATED 51 LIKE KINASE; 5 AMINO 4 IMIDAZOLECARBOXAMIDE; AICA RIBONUCLEOTIDE; CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE KINASE; LIPOPOLYSACCHARIDE; RIBONUCLEOTIDE; SERINE THREONINE PROTEIN KINASE ULK1; TARGET OF RAPAMYCIN KINASE;

EID: 84961136544     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2016.02.002     Document Type: Article
Times cited : (48)

References (66)
  • 1
    • 80051951653 scopus 로고    scopus 로고
    • Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol
    • Puskarich M.A., Trzeciak S., Shapiro N.I., Arnold R.C., Horton J.M., Studnek J.R., et al. Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol. Crit. Care Med. 2011, 39:2066-2071.
    • (2011) Crit. Care Med. , vol.39 , pp. 2066-2071
    • Puskarich, M.A.1    Trzeciak, S.2    Shapiro, N.I.3    Arnold, R.C.4    Horton, J.M.5    Studnek, J.R.6
  • 3
    • 32844464680 scopus 로고    scopus 로고
    • A burning issue: do sepsis and systemic inflammatory response syndrome (SIRS) directly contribute to cardiac dysfunction
    • Ren J., Wu S. A burning issue: do sepsis and systemic inflammatory response syndrome (SIRS) directly contribute to cardiac dysfunction. Front. Biosci. 2006, 11:15-22.
    • (2006) Front. Biosci. , vol.11 , pp. 15-22
    • Ren, J.1    Wu, S.2
  • 4
    • 84940743799 scopus 로고    scopus 로고
    • Septic shock: advances in diagnosis and treatment
    • Seymour C.W., Rosengart M.R. Septic shock: advances in diagnosis and treatment. J. Am. Med. Assoc. 2015, 314:708-717.
    • (2015) J. Am. Med. Assoc. , vol.314 , pp. 708-717
    • Seymour, C.W.1    Rosengart, M.R.2
  • 5
    • 74149084766 scopus 로고    scopus 로고
    • Cardiac overexpression of metallothionein rescues cardiac contractile dysfunction and endoplasmic reticulum stress but not autophagy in sepsis
    • Ceylan-Isik A.F., Zhao P., Zhang B., Xiao X., Su G., Ren J. Cardiac overexpression of metallothionein rescues cardiac contractile dysfunction and endoplasmic reticulum stress but not autophagy in sepsis. J. Mol. Cell. Cardiol. 2010, 48:367-378.
    • (2010) J. Mol. Cell. Cardiol. , vol.48 , pp. 367-378
    • Ceylan-Isik, A.F.1    Zhao, P.2    Zhang, B.3    Xiao, X.4    Su, G.5    Ren, J.6
  • 6
    • 84865324638 scopus 로고    scopus 로고
    • Cardiac-specific overexpression of catalase attenuates lipopolysaccharide-induced myocardial contractile dysfunction: role of autophagy
    • Turdi S., Han X., Huff A.F., Roe N.D., Hu N., Gao F., et al. Cardiac-specific overexpression of catalase attenuates lipopolysaccharide-induced myocardial contractile dysfunction: role of autophagy. Free Radic. Biol. Med. 2012, 53:1327-1338.
    • (2012) Free Radic. Biol. Med. , vol.53 , pp. 1327-1338
    • Turdi, S.1    Han, X.2    Huff, A.F.3    Roe, N.D.4    Hu, N.5    Gao, F.6
  • 7
    • 84904737046 scopus 로고    scopus 로고
    • Ablation of Akt2 protects against lipopolysaccharide-induced cardiac dysfunction: role of Akt ubiquitination E3 ligase TRAF6
    • Zhang Y., Xu X., Ceylan-Isik A.F., Dong M., Pei Z., Li Y., et al. Ablation of Akt2 protects against lipopolysaccharide-induced cardiac dysfunction: role of Akt ubiquitination E3 ligase TRAF6. J. Mol. Cell. Cardiol. 2014, 74C:76-87.
    • (2014) J. Mol. Cell. Cardiol. , vol.74C , pp. 76-87
    • Zhang, Y.1    Xu, X.2    Ceylan-Isik, A.F.3    Dong, M.4    Pei, Z.5    Li, Y.6
  • 8
    • 84857090358 scopus 로고    scopus 로고
    • Sepsis, systemic inflammatory response, and multiple organ dysfunction: The mystery continues
    • Fry D.E. Sepsis, systemic inflammatory response, and multiple organ dysfunction: The mystery continues. Am. Surg. 2012, 78:1-8.
    • (2012) Am. Surg. , vol.78 , pp. 1-8
    • Fry, D.E.1
  • 9
    • 84877355166 scopus 로고
    • Adiponectin knockout accentuates high fat diet-induced obesity and cardiac dysfunction: role of autophagy
    • Guo R., Zhang Y., Turdi S., Ren J. Adiponectin knockout accentuates high fat diet-induced obesity and cardiac dysfunction: role of autophagy. Biochim. Biophys. Acta 1832, 2013:1136-1148.
    • (1832) Biochim. Biophys. Acta , vol.2013 , pp. 1136-1148
    • Guo, R.1    Zhang, Y.2    Turdi, S.3    Ren, J.4
  • 11
    • 34250169052 scopus 로고    scopus 로고
    • Adiponectin and its receptors are expressed in adult ventricular cardiomyocytes and upregulated by activation of peroxisome proliferator-activated receptor gamma
    • Ding G., Qin Q., He N., Francis-David S.C., Hou J., Liu J., et al. Adiponectin and its receptors are expressed in adult ventricular cardiomyocytes and upregulated by activation of peroxisome proliferator-activated receptor gamma. J. Mol. Cell. Cardiol. 2007, 43:73-84.
    • (2007) J. Mol. Cell. Cardiol. , vol.43 , pp. 73-84
    • Ding, G.1    Qin, Q.2    He, N.3    Francis-David, S.C.4    Hou, J.5    Liu, J.6
  • 12
    • 24944532986 scopus 로고    scopus 로고
    • Adiponectin is synthesized and secreted by human and murine cardiomyocytes
    • Pineiro R., Iglesias M.J., Gallego R., Raghay K., Eiras S., Rubio J., et al. Adiponectin is synthesized and secreted by human and murine cardiomyocytes. FEBS Lett. 2005, 579:5163-5169.
    • (2005) FEBS Lett. , vol.579 , pp. 5163-5169
    • Pineiro, R.1    Iglesias, M.J.2    Gallego, R.3    Raghay, K.4    Eiras, S.5    Rubio, J.6
  • 14
    • 33745834319 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
    • Kadowaki T., Yamauchi T., Kubota N., Hara K., Ueki K., Tobe K. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J. Clin. Invest. 2006, 116:1784-1792.
    • (2006) J. Clin. Invest. , vol.116 , pp. 1784-1792
    • Kadowaki, T.1    Yamauchi, T.2    Kubota, N.3    Hara, K.4    Ueki, K.5    Tobe, K.6
  • 15
    • 3142616447 scopus 로고    scopus 로고
    • Adiponectin stimulates angiogenesis in response to tissue ischemia through stimulation of amp-activated protein kinase signaling
    • Shibata R., Ouchi N., Kihara S., Sato K., Funahashi T., Walsh K. Adiponectin stimulates angiogenesis in response to tissue ischemia through stimulation of amp-activated protein kinase signaling. J. Biol. Chem. 2004, 279:28670-28674.
    • (2004) J. Biol. Chem. , vol.279 , pp. 28670-28674
    • Shibata, R.1    Ouchi, N.2    Kihara, S.3    Sato, K.4    Funahashi, T.5    Walsh, K.6
  • 16
    • 19944369735 scopus 로고    scopus 로고
    • Adiponectin-mediated modulation of hypertrophic signals in the heart
    • Shibata R., Ouchi N., Ito M., Kihara S., Shiojima I., Pimentel D.R., et al. Adiponectin-mediated modulation of hypertrophic signals in the heart. Nat. Med. 2004, 10:1384-1389.
    • (2004) Nat. Med. , vol.10 , pp. 1384-1389
    • Shibata, R.1    Ouchi, N.2    Ito, M.3    Kihara, S.4    Shiojima, I.5    Pimentel, D.R.6
  • 17
    • 77951938365 scopus 로고    scopus 로고
    • Adiponectin deficiency promotes the production of inflammatory mediators while severely exacerbating hepatic injury in mice with polymicrobial sepsis
    • Uji Y., Yamamoto H., Maeda K., Tsuchihashi H., Akabori H., Shimizu T., et al. Adiponectin deficiency promotes the production of inflammatory mediators while severely exacerbating hepatic injury in mice with polymicrobial sepsis. J. Surg. Res. 2010, 161:301-311.
    • (2010) J. Surg. Res. , vol.161 , pp. 301-311
    • Uji, Y.1    Yamamoto, H.2    Maeda, K.3    Tsuchihashi, H.4    Akabori, H.5    Shimizu, T.6
  • 18
    • 84900011087 scopus 로고    scopus 로고
    • Loss of caveolin-1 and adiponectin induces severe inflammatory lung injury following LPS challenge through excessive oxidative/nitrative stress
    • Cai L., Yi F., Dai Z., Huang X., Zhao Y.D., Mirza M.K., et al. Loss of caveolin-1 and adiponectin induces severe inflammatory lung injury following LPS challenge through excessive oxidative/nitrative stress. Am. J. Physiol. Lung Cell. Mol. Physiol. 2014, 306:L566-L573.
    • (2014) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.306 , pp. L566-L573
    • Cai, L.1    Yi, F.2    Dai, Z.3    Huang, X.4    Zhao, Y.D.5    Mirza, M.K.6
  • 20
    • 53149129840 scopus 로고    scopus 로고
    • Adiponectin deficiency promotes endothelial activation and profoundly exacerbates sepsis-related mortality
    • Teoh H., Quan A., Bang K.W., Wang G., Lovren F., Vu V., et al. Adiponectin deficiency promotes endothelial activation and profoundly exacerbates sepsis-related mortality. Am. J. Physiol. Endocrinol. Metab. 2008, 295:E658-E664.
    • (2008) Am. J. Physiol. Endocrinol. Metab. , vol.295 , pp. E658-E664
    • Teoh, H.1    Quan, A.2    Bang, K.W.3    Wang, G.4    Lovren, F.5    Vu, V.6
  • 21
    • 84878922289 scopus 로고    scopus 로고
    • Cathepsin K knockout alleviates pressure overload-induced cardiac hypertrophy
    • Hua Y., Xu X., Shi G.P., Chicco A.J., Ren J., Nair S. Cathepsin K knockout alleviates pressure overload-induced cardiac hypertrophy. Hypertension 2013, 61:1184-1192.
    • (2013) Hypertension , vol.61 , pp. 1184-1192
    • Hua, Y.1    Xu, X.2    Shi, G.P.3    Chicco, A.J.4    Ren, J.5    Nair, S.6
  • 22
    • 34147168105 scopus 로고    scopus 로고
    • Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy
    • Matsui Y., Takagi H., Qu X., Abdellatif M., Sakoda H., Asano T., et al. Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ. Res. 2007, 100:914-922.
    • (2007) Circ. Res. , vol.100 , pp. 914-922
    • Matsui, Y.1    Takagi, H.2    Qu, X.3    Abdellatif, M.4    Sakoda, H.5    Asano, T.6
  • 23
    • 84894466528 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor deletion exacerbates pressure overload-induced cardiac hypertrophy through mitigating autophagy
    • Xu X., Hua Y., Nair S., Bucala R., Ren J. Macrophage migration inhibitory factor deletion exacerbates pressure overload-induced cardiac hypertrophy through mitigating autophagy. Hypertension 2014, 63:490-499.
    • (2014) Hypertension , vol.63 , pp. 490-499
    • Xu, X.1    Hua, Y.2    Nair, S.3    Bucala, R.4    Ren, J.5
  • 26
    • 85140415939 scopus 로고
    • Chronic Akt activation attenuated lipopolysaccharide-induced cardiac dysfunction via Akt/GSK3beta-dependent inhibition of apoptosis and ER stress
    • Dong M., Hu N., Hua Y., Xu X., Kandadi M.R., Guo R., et al. Chronic Akt activation attenuated lipopolysaccharide-induced cardiac dysfunction via Akt/GSK3beta-dependent inhibition of apoptosis and ER stress. Biochim. Biophys. Acta 1832, 2013:848-863.
    • (1832) Biochim. Biophys. Acta , vol.2013 , pp. 848-863
    • Dong, M.1    Hu, N.2    Hua, Y.3    Xu, X.4    Kandadi, M.R.5    Guo, R.6
  • 27
    • 84898790765 scopus 로고    scopus 로고
    • Mitochondrial aldehyde dehydrogenase 2 accentuates aging-induced cardiac remodeling and contractile dysfunction: role of AMPK, Sirt1, and mitochondrial function
    • Zhang Y., Mi S.L., Hu N., Doser T.A., Sun A., Ge J., et al. Mitochondrial aldehyde dehydrogenase 2 accentuates aging-induced cardiac remodeling and contractile dysfunction: role of AMPK, Sirt1, and mitochondrial function. Free Radic. Biol. Med. 2014, 71:208-220.
    • (2014) Free Radic. Biol. Med. , vol.71 , pp. 208-220
    • Zhang, Y.1    Mi, S.L.2    Hu, N.3    Doser, T.A.4    Sun, A.5    Ge, J.6
  • 28
    • 84881523187 scopus 로고    scopus 로고
    • AICAR-dependent AMPK activation improves scar formation in the aged heart in a murine model of reperfused myocardial infarction
    • Cieslik K.A., Taffet G.E., Crawford J.R., Trial J., Mejia Osuna P., Entman M.L. AICAR-dependent AMPK activation improves scar formation in the aged heart in a murine model of reperfused myocardial infarction. J. Mol. Cell. Cardiol. 2013, 63:26-36.
    • (2013) J. Mol. Cell. Cardiol. , vol.63 , pp. 26-36
    • Cieslik, K.A.1    Taffet, G.E.2    Crawford, J.R.3    Trial, J.4    Mejia Osuna, P.5    Entman, M.L.6
  • 29
    • 84893490518 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor deficiency augments doxorubicin-induced cardiomyopathy
    • Xu X., Bucala R., Ren J. Macrophage migration inhibitory factor deficiency augments doxorubicin-induced cardiomyopathy. J. Am. Heart Assoc. 2013, 2.
    • (2013) J. Am. Heart Assoc. , vol.2
    • Xu, X.1    Bucala, R.2    Ren, J.3
  • 30
    • 20344366837 scopus 로고    scopus 로고
    • Inhibition of sarco(endo)plasmic reticulum Ca2+-ATPase differentially regulates contractile function in cardiac myocytes from normotensive and spontaneously hypertensive rats: role of Ca2+ regulatory proteins
    • Li S.Y., Golden K.L., Jiang Y., Wang G.J., Privratsky J.R., Zhang X., et al. Inhibition of sarco(endo)plasmic reticulum Ca2+-ATPase differentially regulates contractile function in cardiac myocytes from normotensive and spontaneously hypertensive rats: role of Ca2+ regulatory proteins. Cell Biochem. Biophys. 2005, 42:1-12.
    • (2005) Cell Biochem. Biophys. , vol.42 , pp. 1-12
    • Li, S.Y.1    Golden, K.L.2    Jiang, Y.3    Wang, G.J.4    Privratsky, J.R.5    Zhang, X.6
  • 31
    • 84907507161 scopus 로고    scopus 로고
    • The effects of LPS-induced endotoxemia on the expression of adiponectin and its receptors in female rats
    • Iwasa T., Matsuzaki T., Matsui S., Munkhzaya M., Tungalagsuvd A., Kawami T., et al. The effects of LPS-induced endotoxemia on the expression of adiponectin and its receptors in female rats. Endocr. J. 2014.
    • (2014) Endocr. J.
    • Iwasa, T.1    Matsuzaki, T.2    Matsui, S.3    Munkhzaya, M.4    Tungalagsuvd, A.5    Kawami, T.6
  • 32
    • 84886729097 scopus 로고    scopus 로고
    • Mild obesity reduces survival and adiponectin sensitivity in endotoxemic rats
    • Sakai S., Iizuka N., Fujiwara M., Miyoshi M., Aoyama M., Maeshige N., et al. Mild obesity reduces survival and adiponectin sensitivity in endotoxemic rats. J Surg Res. 2013, 185:353-363.
    • (2013) J Surg Res. , vol.185 , pp. 353-363
    • Sakai, S.1    Iizuka, N.2    Fujiwara, M.3    Miyoshi, M.4    Aoyama, M.5    Maeshige, N.6
  • 33
    • 63849162173 scopus 로고    scopus 로고
    • AMP-activated protein kinase: a core signalling pathway in the heart
    • Kim A.S., Miller E.J., Young L.H. AMP-activated protein kinase: a core signalling pathway in the heart. Acta Physiol (Oxf.) 2009, 196:37-53.
    • (2009) Acta Physiol (Oxf.) , vol.196 , pp. 37-53
    • Kim, A.S.1    Miller, E.J.2    Young, L.H.3
  • 34
    • 68049103917 scopus 로고    scopus 로고
    • Activation and signaling by the AMP-activated protein kinase in endothelial cells
    • Fisslthaler B., Fleming I. Activation and signaling by the AMP-activated protein kinase in endothelial cells. Circ. Res. 2009, 105:114-127.
    • (2009) Circ. Res. , vol.105 , pp. 114-127
    • Fisslthaler, B.1    Fleming, I.2
  • 35
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • Mizushima N., Yoshimori T., Levine B. Methods in mammalian autophagy research. Cell 2010, 140:313-326.
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 36
    • 27944504351 scopus 로고    scopus 로고
    • P62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
    • Bjorkoy G., Lamark T., Brech A., Outzen H., Perander M., Overvatn A., et al. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J. Cell Biol. 2005, 171:603-614.
    • (2005) J. Cell Biol. , vol.171 , pp. 603-614
    • Bjorkoy, G.1    Lamark, T.2    Brech, A.3    Outzen, H.4    Perander, M.5    Overvatn, A.6
  • 37
    • 84892171140 scopus 로고    scopus 로고
    • An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies
    • Musumeci D., Roviello G.N., Montesarchio D. An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies. Pharmacol. Ther. 2014, 141:347-357.
    • (2014) Pharmacol. Ther. , vol.141 , pp. 347-357
    • Musumeci, D.1    Roviello, G.N.2    Montesarchio, D.3
  • 38
    • 33646804552 scopus 로고    scopus 로고
    • Cardiomyocyte function after burn injury and lipopolysaccharide exposure: single-cell contraction analysis and cytokine secretion profile
    • Niederbichler A.D., Westfall M.V., Su G.L., Donnerberg J., Usman A., Vogt P.M., et al. Cardiomyocyte function after burn injury and lipopolysaccharide exposure: single-cell contraction analysis and cytokine secretion profile. Shock 2006, 25:176-183.
    • (2006) Shock , vol.25 , pp. 176-183
    • Niederbichler, A.D.1    Westfall, M.V.2    Su, G.L.3    Donnerberg, J.4    Usman, A.5    Vogt, P.M.6
  • 39
    • 67749122387 scopus 로고    scopus 로고
    • Cardiac-specific overexpression of insulin-like growth factor I (IGF-1) rescues lipopolysaccharide-induced cardiac dysfunction and activation of stress signaling in murine cardiomyocytes
    • Zhao P., Turdi S., Dong F., Xiao X., Su G., Zhu X., et al. Cardiac-specific overexpression of insulin-like growth factor I (IGF-1) rescues lipopolysaccharide-induced cardiac dysfunction and activation of stress signaling in murine cardiomyocytes. Shock 2009, 32:100-107.
    • (2009) Shock , vol.32 , pp. 100-107
    • Zhao, P.1    Turdi, S.2    Dong, F.3    Xiao, X.4    Su, G.5    Zhu, X.6
  • 40
    • 0036511213 scopus 로고    scopus 로고
    • ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism
    • Berg A.H., Combs T.P., Scherer P.E. ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol. Metab. 2002, 13:84-89.
    • (2002) Trends Endocrinol. Metab. , vol.13 , pp. 84-89
    • Berg, A.H.1    Combs, T.P.2    Scherer, P.E.3
  • 41
    • 84862922916 scopus 로고    scopus 로고
    • Adiponectin attenuates lipopolysaccharide-induced acute lung injury through suppression of endothelial cell activation
    • Konter J.M., Parker J.L., Baez E., Li S.Z., Ranscht B., Denzel M., et al. Adiponectin attenuates lipopolysaccharide-induced acute lung injury through suppression of endothelial cell activation. J. Immunol. 2012, 188:854-863.
    • (2012) J. Immunol. , vol.188 , pp. 854-863
    • Konter, J.M.1    Parker, J.L.2    Baez, E.3    Li, S.Z.4    Ranscht, B.5    Denzel, M.6
  • 42
    • 3042699353 scopus 로고    scopus 로고
    • Adiponectin protects LPS-induced liver injury through modulation of TNF-alpha in KK-Ay obese mice
    • Masaki T., Chiba S., Tatsukawa H., Yasuda T., Noguchi H., Seike M., et al. Adiponectin protects LPS-induced liver injury through modulation of TNF-alpha in KK-Ay obese mice. Hepatology 2004, 40:177-184.
    • (2004) Hepatology , vol.40 , pp. 177-184
    • Masaki, T.1    Chiba, S.2    Tatsukawa, H.3    Yasuda, T.4    Noguchi, H.5    Seike, M.6
  • 43
    • 33745298775 scopus 로고    scopus 로고
    • Adiponectin deficiency exacerbates lipopolysaccharide/d-galactosamine-induced liver injury in mice
    • Matsumoto H., Tamura S., Kamada Y., Kiso S., Fukushima J., Wada A., et al. Adiponectin deficiency exacerbates lipopolysaccharide/d-galactosamine-induced liver injury in mice. World J. Gastroenterol. 2006, 12:3352-3358.
    • (2006) World J. Gastroenterol. , vol.12 , pp. 3352-3358
    • Matsumoto, H.1    Tamura, S.2    Kamada, Y.3    Kiso, S.4    Fukushima, J.5    Wada, A.6
  • 44
    • 84866404225 scopus 로고    scopus 로고
    • Calcium/calmodulin-dependent protein kinase kinase 2: roles in signaling and pathophysiology
    • Racioppi L., Means A.R. Calcium/calmodulin-dependent protein kinase kinase 2: roles in signaling and pathophysiology. J. Biol. Chem. 2012, 287:31658-31665.
    • (2012) J. Biol. Chem. , vol.287 , pp. 31658-31665
    • Racioppi, L.1    Means, A.R.2
  • 45
    • 77953681258 scopus 로고    scopus 로고
    • Impact of a single intracoronary administration of adiponectin on myocardial ischemia/reperfusion injury in a pig model
    • Kondo K., Shibata R., Unno K., Shimano M., Ishii M., Kito T., et al. Impact of a single intracoronary administration of adiponectin on myocardial ischemia/reperfusion injury in a pig model. Circ. Cardiovasc. Interv. 2010, 3:166-173.
    • (2010) Circ. Cardiovasc. Interv. , vol.3 , pp. 166-173
    • Kondo, K.1    Shibata, R.2    Unno, K.3    Shimano, M.4    Ishii, M.5    Kito, T.6
  • 46
    • 27144457438 scopus 로고    scopus 로고
    • Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms
    • Shibata R., Sato K., Pimentel D.R., Takemura Y., Kihara S., Ohashi K., et al. Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms. Nat. Med. 2005, 11:1096-1103.
    • (2005) Nat. Med. , vol.11 , pp. 1096-1103
    • Shibata, R.1    Sato, K.2    Pimentel, D.R.3    Takemura, Y.4    Kihara, S.5    Ohashi, K.6
  • 47
    • 34249670301 scopus 로고    scopus 로고
    • Adiponectin protects against the development of systolic dysfunction following myocardial infarction
    • Shibata R., Izumiya Y., Sato K., Papanicolaou K., Kihara S., Colucci W.S., et al. Adiponectin protects against the development of systolic dysfunction following myocardial infarction. J. Mol. Cell. Cardiol. 2007, 42:1065-1074.
    • (2007) J. Mol. Cell. Cardiol. , vol.42 , pp. 1065-1074
    • Shibata, R.1    Izumiya, Y.2    Sato, K.3    Papanicolaou, K.4    Kihara, S.5    Colucci, W.S.6
  • 48
    • 58849116697 scopus 로고    scopus 로고
    • Adiponectin improves cardiomyocyte contractile function in db/db diabetic obese mice
    • Dong F., Ren J. Adiponectin improves cardiomyocyte contractile function in db/db diabetic obese mice. Obesity (Silver Spring) 2009, 17:262-268.
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 262-268
    • Dong, F.1    Ren, J.2
  • 49
    • 77954959087 scopus 로고    scopus 로고
    • Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heart
    • Ma H., Wang J., Thomas D.P., Tong C., Leng L., Wang W., et al. Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heart. Circulation 2010, 122:282-292.
    • (2010) Circulation , vol.122 , pp. 282-292
    • Ma, H.1    Wang, J.2    Thomas, D.P.3    Tong, C.4    Leng, L.5    Wang, W.6
  • 50
    • 84861398110 scopus 로고    scopus 로고
    • Deficiency in AMPK attenuates ethanol-induced cardiac contractile dysfunction through inhibition of autophagosome formation
    • Guo R., Ren J. Deficiency in AMPK attenuates ethanol-induced cardiac contractile dysfunction through inhibition of autophagosome formation. Cardiovasc. Res. 2012, 94:480-491.
    • (2012) Cardiovasc. Res. , vol.94 , pp. 480-491
    • Guo, R.1    Ren, J.2
  • 51
    • 84876220612 scopus 로고    scopus 로고
    • Regulation of interplay between autophagy and apoptosis in the diabetic heart: new role of AMPK
    • Zou M.H., Xie Z. Regulation of interplay between autophagy and apoptosis in the diabetic heart: new role of AMPK. Autophagy 2013, 9:624-625.
    • (2013) Autophagy , vol.9 , pp. 624-625
    • Zou, M.H.1    Xie, Z.2
  • 52
    • 84916622634 scopus 로고    scopus 로고
    • Role of autophagy in metabolic syndrome-associated heart disease
    • Ren S.Y., Xu X. Role of autophagy in metabolic syndrome-associated heart disease. Biochim. Biophys. Acta 2014.
    • (2014) Biochim. Biophys. Acta
    • Ren, S.Y.1    Xu, X.2
  • 53
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B., Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008, 132:27-42.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 54
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • Mizushima N., Levine B., Cuervo A.M., Klionsky D.J. Autophagy fights disease through cellular self-digestion. Nature 2008, 451:1069-1075.
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 55
    • 11144245626 scopus 로고    scopus 로고
    • The role of autophagy during the early neonatal starvation period
    • Kuma A., Hatano M., Matsui M., Yamamoto A., Nakaya H., Yoshimori T., et al. The role of autophagy during the early neonatal starvation period. Nature 2004, 432:1032-1036.
    • (2004) Nature , vol.432 , pp. 1032-1036
    • Kuma, A.1    Hatano, M.2    Matsui, M.3    Yamamoto, A.4    Nakaya, H.5    Yoshimori, T.6
  • 56
    • 34249714158 scopus 로고    scopus 로고
    • The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
    • Nakai A., Yamaguchi O., Takeda T., Higuchi Y., Hikoso S., Taniike M., et al. The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress. Nat. Med. 2007, 13:619-624.
    • (2007) Nat. Med. , vol.13 , pp. 619-624
    • Nakai, A.1    Yamaguchi, O.2    Takeda, T.3    Higuchi, Y.4    Hikoso, S.5    Taniike, M.6
  • 58
    • 79959385996 scopus 로고    scopus 로고
    • Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice
    • Xie Z., Lau K., Eby B., Lozano P., He C., Pennington B., et al. Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice. Diabetes 2011, 60:1770-1778.
    • (2011) Diabetes , vol.60 , pp. 1770-1778
    • Xie, Z.1    Lau, K.2    Eby, B.3    Lozano, P.4    He, C.5    Pennington, B.6
  • 59
    • 84880065357 scopus 로고    scopus 로고
    • Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes
    • Xu X., Kobayashi S., Chen K., Timm D., Volden P., Huang Y., et al. Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes. J. Biol. Chem. 2013, 288:18077-18092.
    • (2013) J. Biol. Chem. , vol.288 , pp. 18077-18092
    • Xu, X.1    Kobayashi, S.2    Chen, K.3    Timm, D.4    Volden, P.5    Huang, Y.6
  • 60
    • 84908478414 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-mediated autophagy protects against lipopolysaccharide-induced apoptosis in HL-1 cardiomyocytes
    • Zou X., Xu J., Yao S., Li J., Yang Y., Yang L. Endoplasmic reticulum stress-mediated autophagy protects against lipopolysaccharide-induced apoptosis in HL-1 cardiomyocytes. Exp. Physiol. 2014.
    • (2014) Exp. Physiol.
    • Zou, X.1    Xu, J.2    Yao, S.3    Li, J.4    Yang, Y.5    Yang, L.6
  • 62
    • 79957446643 scopus 로고    scopus 로고
    • Heme oxygenase-1-mediated autophagy protects against hepatocyte cell death and hepatic injury from infection/sepsis in mice
    • Carchman E.H., Rao J., Loughran P.A., Rosengart M.R., Zuckerbraun B.S. Heme oxygenase-1-mediated autophagy protects against hepatocyte cell death and hepatic injury from infection/sepsis in mice. Hepatology 2011, 53:2053-2062.
    • (2011) Hepatology , vol.53 , pp. 2053-2062
    • Carchman, E.H.1    Rao, J.2    Loughran, P.A.3    Rosengart, M.R.4    Zuckerbraun, B.S.5
  • 64
    • 84934913021 scopus 로고    scopus 로고
    • Cardiac-specific overexpression of metallothionein attenuates myocardial remodeling and contractile dysfunction in L-NAME-induced experimental hypertension: role of autophagy regulation
    • Yang L., Gao J.Y., Ma J., Xu X., Wang Q., Xiong L., et al. Cardiac-specific overexpression of metallothionein attenuates myocardial remodeling and contractile dysfunction in L-NAME-induced experimental hypertension: role of autophagy regulation. Toxicol. Lett. 2015, 237:121-132.
    • (2015) Toxicol. Lett. , vol.237 , pp. 121-132
    • Yang, L.1    Gao, J.Y.2    Ma, J.3    Xu, X.4    Wang, Q.5    Xiong, L.6
  • 65
    • 84948825234 scopus 로고    scopus 로고
    • Defects in calcium homeostasis and mitochondria can be reversed in Pompe disease
    • Lim J.A., Li L., Kakhlon O., Myerowitz R., Raben N. Defects in calcium homeostasis and mitochondria can be reversed in Pompe disease. Autophagy 2015, 11:385-402.
    • (2015) Autophagy , vol.11 , pp. 385-402
    • Lim, J.A.1    Li, L.2    Kakhlon, O.3    Myerowitz, R.4    Raben, N.5


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