Differential cytotoxic effects of 7-dehydrocholesterol-derived oxysterols on cultured retina-derived cells: Dependence on sterol structure, cell type, and density

Experimental Eye Research

Volumn 145, Issue , 2016, Pages 297-316

  Pfeffer, Bruce A ^a,b,c   Xu, Libin ^d   Porter, Ned A ^e   Rao, Sriganesh Ramachandra ^a,b,c   Fliesler, Steven J ^a,b,c  

^a VA WESTERN NEW YORK HEALTHCARE SYSTEM   (United States)

^b SUNY EYE INSTITUTE   (United States)

^c UNIVERSITY AT BUFFALO   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

^e VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cell culture; Cell viability assay; M ller cell; Oxysterol; Photoreceptor; Retinal pigment epithelium

Indexed keywords

3BETA,5ALPHA DIHYDROXYCHOLEST 7 EN 6 ONE; 4BETA HYDROXY 7 DEHYDROCHOLESTEROL; 5,9 ENDOPEROXY CHOLEST 7 EN 3BETA,6ALPHA DIOL; 7 DEHYDROCHOLESTEROL; 7 OXOCHOLESTEROL; OXYSTEROL; UNCLASSIFIED DRUG; 7-DEHYDROCHOLESTEROL;

ANIMAL CELL; ARTICLE; CELL DENSITY; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DIPLOIDY; EC50; GLIA CELL; MUELLER CELL; NONHUMAN; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RETINA CELL; RETINA DEGENERATION; ANIMAL; ANIMAL MODEL; CELL COUNT; CELL CULTURE; CELL DEATH; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; EPITHELIUM CELL; MACROGLIA; METABOLISM; RAT; RETINA; RETINAL PIGMENT EPITHELIUM; RHESUS MONKEY; VERTEBRATE PHOTORECEPTOR CELL;

ANIMALS; CELL COUNT; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; DEHYDROCHOLESTEROLS; EPENDYMOGLIAL CELLS; EPITHELIAL CELLS; MACACA MULATTA; MODELS, ANIMAL; OXYSTEROLS; PHOTORECEPTOR CELLS, VERTEBRATE; RATS; RETINA; RETINAL PIGMENT EPITHELIUM;

EID: 84960905703     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2016.01.016     Document Type: Article

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