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Defective cholesterol biosynthesis associated with the Smith-Lemli-Opitz syndrome
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Markedly increased tissue concentrations of 7-dehydrocholesterol combined with low levels of cholesterol are characteristic of the Smith-Lemli-Opitz syndrome
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Reproducing abnormal cholesterol biosynthesis as seen in the Smith-Lemli-Opitz syndrome by inhibiting the conversion of 7-dehydrocholesterol to cholesterol in rats
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Xu, G., G. Salen, S. Shefer, G.C. Ness, T.S. Chen, Z. Zhao, and G.S. Tint (1995) Reproducing abnormal cholesterol biosynthesis as seen in the Smith-Lemli-Opitz syndrome by inhibiting the conversion of 7-dehydrocholesterol to cholesterol in rats. J. Clin. Invest., 95:76-81.
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