Andrographolide stimulates p38 mitogen-activated protein kinase-nuclear factor erythroid-2-related factor 2-heme oxygenase 1 signaling in primary cerebral endothelial cells for definite protection against ischemic stroke in rats

Translational Research

Volumn 170, Issue , 2016, Pages 57-72

  Yen, Ting Lin ^a   Chen, Ray Jade ^b,c   Jayakumar, Thanasekaran ^a   Lu, Wan Jung ^a,c   Hsieh, Cheng Ying ^a   Hsu, Ming Jen ^a   Yang, Chih Hao ^a   Chang, Chao Chien ^a,d   Lin, Yen Kuang ^e   Lin, Kuan Hung ^a,f   Sheu, Joen Rong ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d CATHAY GENERAL HOSPITAL   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^f SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANDROGRAPHOLIDE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; HEME OXYGENASE 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUROPROTECTIVE AGENT; TRANSCRIPTION FACTOR NRF2; DITERPENE; HMOX1 PROTEIN, MOUSE; MEMBRANE PROTEIN; NFE2L2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CAPILLARY; BRAIN CELL; BRAIN INFARCTION; BRAIN ISCHEMIA; CELL DEATH; CELL GROWTH; CELL NUCLEUS; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE TRANSLOCATION; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; ANIMAL; BRAIN EDEMA; C57BL MOUSE; CELL CULTURE; CEREBRAL INFARCTION; CYTOLOGY; DRUG EFFECTS; METABOLISM; PATHOLOGY; REPRODUCIBILITY; SIGNAL TRANSDUCTION; STROKE; VASCULAR ENDOTHELIUM; WISTAR RAT;

ANIMALS; BRAIN EDEMA; BRAIN ISCHEMIA; CELLS, CULTURED; CEREBRAL INFARCTION; DITERPENES; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HEME OXYGENASE-1; MALE; MEMBRANE PROTEINS; MICE, INBRED C57BL; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS, WISTAR; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION; STROKE;

EID: 84960795776     PISSN: 19315244     EISSN: 18781810     Source Type: Journal    
DOI: 10.1016/j.trsl.2015.12.002     Document Type: Article

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