Polymorphisms at the F12 and KLKB1 loci have significant trait association with activation of the renin-angiotensin system

BMC Medical Genetics

Volumn 17, Issue 1, 2016, Pages

  Biswas, Nilima ^a   Maihofer, Adam X ^b   Mir, Saiful Anam ^a   Rao, Fangwen ^a   Zhang, Kuixing ^a   Khandrika, Srikrishna ^a   Mahata, Manjula ^a   Friese, Ryan S ^a   Hightower, C Makena ^a   Mahata, Sushil K ^a   Baker, Dewleen G ^a,b   Nievergelt, Caroline M ^a,b   Vaingankar, Sucheta M ^a   O'Connor, Daniel T ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

FXIIa (active protease encoded by gene F12 or Hageman factor); Hypertension; Kallikrein KAL (active protease encoded for by gene KLKB1 or Fletcher factor); PTSD (posttraumatic stress disorder); Rs1801020; Rs3733402

Indexed keywords

KALLIKREIN; RENIN; ANGIOTENSIN I; ANGIOTENSINOGEN; BLOOD CLOTTING FACTOR 12A; KCTD11 PROTEIN, MOUSE; NERVE PROTEIN; PREKALLIKREIN; SERINE PROTEINASE; ZYMOGEN E;

ADOLESCENT; ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; CONTROLLED STUDY; DIZYGOTIC TWINS; F12 GENE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC TRAIT; HUMAN; HYPERTENSION; KLKB1 GENE; MALE; MARKER GENE; MONOZYGOTIC TWINS; MOUSE; NONHUMAN; NORMAL HUMAN; OXIDATIVE STRESS; PLASMA RENIN ACTIVITY; PROTEIN LOCALIZATION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SIBLING; ALLELE; ANIMAL; BLOOD; BLOOD PRESSURE; CELL LINE; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GENOTYPING TECHNIQUE; JUXTAGLOMERULAR APPARATUS; METABOLISM; MIDDLE AGED; SINGLE NUCLEOTIDE POLYMORPHISM; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ALLELES; ANGIOTENSIN I; ANGIOTENSINOGEN; ANIMALS; BLOOD PRESSURE; CELL LINE; FACTOR XIIA; GENE EXPRESSION REGULATION; GENETIC LOCI; GENOME-WIDE ASSOCIATION STUDY; GENOTYPING TECHNIQUES; HUMANS; HYPERTENSION; JUXTAGLOMERULAR APPARATUS; KALLIKREINS; MALE; MICE; MIDDLE AGED; NERVE TISSUE PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PREKALLIKREIN; RENIN; RENIN-ANGIOTENSIN SYSTEM; SERINE ENDOPEPTIDASES; YOUNG ADULT;

EID: 84960469823     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/s12881-016-0283-5     Document Type: Article

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