Chip-based direct genotyping of coding variants in genome wide association studies: Utility, issues and prospects

Gene

Volumn 540, Issue 1, 2014, Pages 104-109

  Nievergelt, Caroline M ^a   Wineinger, Nathan E ^b   Libiger, Ondrej ^c   Pham, Phillip ^d   Zhang, Guangfa ^e   Baker, Dewleen G ^a   Schork, Nicholas J ^f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SCRIPPS TRANSLATIONAL SCIENCE INSTITUTE   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d Cypher Genomics Inc   (United States)

^e Human Longevity Inc   (United States)

^f J CRAIG VENTER INSTITUTE   (United States)

Author keywords

Coding variants; Expanding GWAS; Genotyping rare SNPs; Illumina HumanExome array

Indexed keywords

DNA; MITOCHONDRIAL DNA;

ADULT; AFRICAN AMERICAN; AMERICAN INDIAN; ARTICLE; ASIAN; BIOCHIP; CODING VARIANT; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DNA MICROARRAY; ETHNICITY; EUROPEAN AMERICAN; FEMALE; GENE DELETION; GENE FREQUENCY; GENE INSERTION; GENETIC ASSOCIATION; GENETIC CODE; GENETIC VARIABILITY; GENOTYPING TECHNIQUE; HISPANIC; HUMAN; HUMAN GENOME; HUMAN OMNI EXPRESS EXOME ARRAY; ILLUMINA HUMAN EXOME ARRAY; MAJOR CLINICAL STUDY; MALE; PACIFIC ISLANDER; PRIORITY JOURNAL; SELF REPORT; SINGLE NUCLEOTIDE POLYMORPHISM; Y CHROMOSOME; YOUNG ADULT;

CODING VARIANTS; EXPANDING GWAS; GENOTYPING RARE SNPS; ILLUMINA HUMANEXOME ARRAY;

ADULT; CHROMATIN IMMUNOPRECIPITATION; EXOME; FEMALE; GENE FREQUENCY; GENETIC MARKERS; GENOME-WIDE ASSOCIATION STUDY; GENOTYPING TECHNIQUES; HUMANS; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA; YOUNG ADULT;

EID: 84895864675     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2014.01.069     Document Type: Article

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