Integrated computational and experimental analysis of the neuroendocrine transcriptome in genetic hypertension identifies novel control points for the cardiometabolic syndrome

Circulation: Cardiovascular Genetics

Volumn 5, Issue 4, 2012, Pages 430-440

  Friese, Ryan S ^a,b   Ye, Chun ^d   Nievergelt, Caroline M ^c   Schork, Andrew J ^b   Mahapatra, Nitish R ^h   Rao, Fangwen ^b   Napolitan, Philip S ^b   Waalen, Jill ^k   Ehret, Georg B ^j   Munroe, Patricia B ⁱ   Schmid Schönbein, Geert W ^a   Eskin, Eleazar ^g   O'Connor, Daniel T ^b,c,e,f  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c Department of Pharmacology ^*  (United States)

^d Bioinformatics Program   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h INDIAN INSTITUTE OF TECHNOLOGY MADRAS   (India)

ⁱ QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^j JOHNS HOPKINS UNIVERSITY   (United States)

^k SCRIPPS RESEARCH INSTITUTE   (United States)

more..

Author keywords

BPH mouse strain; Complex trait; Essential (genetic) hypertension; Human genetics; Metabolic syndrome

Indexed keywords

COMPLEMENTARY DNA; DNA; LUCIFERASE; TRANSCRIPTION FACTOR YY1;

ADRENAL GLAND; ALGORITHM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; BODY MASS; COMPUTER ANALYSIS; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ESSENTIAL HYPERTENSION; GENE EXPRESSION REGULATION; GENOTYPE; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN GENETICS; MALE; METABOLIC SYNDROME X; MICROARRAY ANALYSIS; MOUSE; MOUSE STRAIN; NONHUMAN; POPULATION GENETICS; PREDICTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN MOTIF; REPORTER GENE; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTOLIC BLOOD PRESSURE; TRANSCRIPTION REGULATION;

ADRENAL GLANDS; ANIMALS; BASE SEQUENCE; BLOOD PRESSURE; COMPUTATIONAL BIOLOGY; ENHANCER ELEMENTS, GENETIC; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERTENSION; LUCIFERASES; MALE; META-ANALYSIS AS TOPIC; METABOLIC SYNDROME X; MICE; MOLECULAR SEQUENCE DATA; MYOCARDIUM; NEUROSECRETORY SYSTEMS; NUCLEOTIDE MOTIFS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RNA, MESSENGER; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; TRANSCRIPTOME;

ANIMALIA;

EID: 84868618810     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.111.962415     Document Type: Article

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