Central Insulin Action Activates Kupffer Cells by Suppressing Hepatic Vagal Activation via the Nicotinic Alpha 7 Acetylcholine Receptor

Cell Reports

Volumn 14, Issue 10, 2016, Pages 2362-2374

  Kimura, Kumi ^a   Tanida, Mamoru ^b   Nagata, Naoto ^a   Inaba, Yuka ^a   Watanabe, Hitoshi ^a   Nagashimada, Mayumi ^a   Ota, Tsuguhito ^a   Asahara, Shun Ichiro ^c   Kido, Yoshiaki ^c,d   Matsumoto, Michihiro ^e   Toshinai, Koji ^f,g   Nakazato, Masamitsu ^f   Shibamoto, Toshishige ^b   Kaneko, Shuichi ^a   Kasuga, Masato ^h   Inoue, Hiroshi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b KANAZAWA MEDICAL UNIVERSITY   (Japan)

^c KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d KOBE UNIVERSITY   (Japan)

^e Research Institute   (Japan)

^f UNIVERSITY OF MIYAZAKI   (Japan)

^g Chukyo Women's University   (Japan)

^h NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BUNGAROTOXIN RECEPTOR; GLUCOSE 6 PHOSPHATASE; INSULIN; INTERLEUKIN 6; STAT3 PROTEIN; ACETYLCHOLINE; CELL SURFACE RECEPTOR; CHLORISONDAMINE; EMR1 PROTEIN, MOUSE; GLUCOSE BLOOD LEVEL; NICOTINE; PROTEIN BINDING;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CHOLINERGIC ACTIVITY; CONTROLLED STUDY; DIET INDUCED OBESITY; GENE EXPRESSION REGULATION; INSULIN RESISTANCE; KNOCKOUT MOUSE; KUPFFER CELL; LIPID DIET; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VAGOTOMY; VAGUS NERVE; ANALYSIS; ANIMAL; BLOOD; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DEFICIENCY; DRUG EFFECTS; GENETICS; GLUCOSE BLOOD LEVEL; LIVER; MALE; METABOLISM; OBESITY; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY;

ACETYLCHOLINE; ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ANIMALS; BLOOD GLUCOSE; CELLS, CULTURED; CHLORISONDAMINE; DIET, HIGH-FAT; INSULIN; INTERLEUKIN-6; KUPFFER CELLS; LIVER; MALE; MICE; MICE, INBRED C57BL; NICOTINE; OBESITY; PHOSPHORYLATION; PROTEIN BINDING; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; VAGUS NERVE;

EID: 84960444062     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.02.032     Document Type: Article

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