Leptin receptor signaling in the hypothalamus regulates hepatic autonomic nerve activity via phosphatidylinositol 3-kinase and AMP-activated protein kinase

Journal of Neuroscience

Volumn 35, Issue 2, 2015, Pages 474-484

  Tanida, Mamoru ^a,c   Yamamoto, Naoki ^b   Morgan, Donald A ^c   Kurata, Yasutaka ^a   Shibamoto, Toshishige ^a   Rahmouni, Kamal ^c  

^a KANAZAWA MEDICAL UNIVERSITY   (Japan)

^b HOKURIKU UNIVERSITY   (Japan)

^c UNIVERSITY OF IOWA   (United States)

Author keywords

AMPK; Autonomic function; Leptin; Liver; PI3K

Indexed keywords

1, 4 DIAMINO 1, 4 BIS (2 AMINOPHENYLTHIO) 2, 3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL) IMIDAZOLE; GLUCOSE; HEXAMETHONIUM BROMIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LEPTIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAT3 PROTEIN; UNCLASSIFIED DRUG; LEPTIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; AUTONOMIC NERVOUS SYSTEM FUNCTION; BIOCHEMISTRY; BRAIN ELECTROPHYSIOLOGY; BRAIN FUNCTION; CANNULATION; CONTROLLED STUDY; HEPATIC AUTONOMIC NERVE ACTIVITY; HYPOTHALAMUS; LIVER CELL; LIVER FUNCTION; MALE; MICROINJECTION; MOUSE; NERVE CONDUCTION; NERVE POTENTIAL; NERVE STIMULATION; NONHUMAN; PARASYMPATHETIC TONE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SYMPATHETIC NERVE; VAGUS NERVE; ANIMAL; DRUG EFFECTS; INNERVATION; LIVER; METABOLISM; PHYSIOLOGY; WISTAR RAT;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; HYPOTHALAMUS; LEPTIN; LIVER; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3-KINASES; RATS; RATS, WISTAR; RECEPTORS, LEPTIN; STAT3 TRANSCRIPTION FACTOR; VAGUS NERVE;

EID: 84920982519     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1828-14.2015     Document Type: Article

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