Loss of exosomes in progranulin-associated frontotemporal dementia

Neurobiology of Aging

Volumn 40, Issue , 2016, Pages 41-49

  Benussi, Luisa ^a   Ciani, Miriam ^a   Tonoli, Elisa ^a   Morbin, Michela ^b   Palamara, Luisa ^b   Albani, Diego ^c   Fusco, Federica ^c   Forloni, Gianluigi ^c   Glionna, Michela ^a   Baco, Monika ^a   Paterlini, Anna ^a   Fostinelli, Silvia ^a   Santini, Benedetta ^d   Galbiati, Elisabetta ^d   Gagni, Paola ^e   Cretich, Marina ^e   Binetti, Giuliano ^a   Tagliavini, Fabrizio ^b   Prosperi, Davide ^d   Chiari, Marcella ^e   Ghidoni, Roberta ^a   more..

^a IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

^b DEPARTMENT OF NEUROSURGERY   (Italy)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^d UNIVERSITY OF MILANO BICOCCA   (Italy)

^e CNR   (Italy)

Author keywords

Exosomes; Extracellular vesicles; GRN; Human primary fibroblasts; Null mutations; Progranulin

Indexed keywords

PROGRANULIN; GRN PROTEIN, HUMAN; SIGNAL PEPTIDE;

ANIMAL CELL; ARTICLE; BIOCHEMICAL COMPOSITION; CELL COMMUNICATION; CELL COUNT; CELL LOSS; CONTROLLED STUDY; EXOSOME; FRONTOTEMPORAL DEMENTIA; GENE MUTATION; GENE SILENCING; GENETIC ASSOCIATION; GRN GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MOLECULAR PATHOLOGY; MOUSE; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROGRANULIN BLOOD LEVEL; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; PROTEIN SECRETION; PROTEIN TRANSPORT; SH SY5Y CELL; SKIN FIBROBLAST; AGED; BRAIN; CELL CULTURE; FEMALE; FIBROBLAST; GENETICS; MALE; MIDDLE AGED; MOLECULARLY TARGETED THERAPY; MUTATION; PATHOLOGY; PHYSIOLOGY; SECRETION (PROCESS);

AGED; BRAIN; CELLS, CULTURED; EXOSOMES; FEMALE; FIBROBLASTS; FRONTOTEMPORAL DEMENTIA; GENE SILENCING; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; MOLECULAR TARGETED THERAPY; MUTATION;

EID: 84960406260     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2016.01.001     Document Type: Article

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