Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency

Human Molecular Genetics

Volumn 23, Issue 6, 2014, Pages 1467-1478

  Lee, Wing C ^a   Almeida, Sandra ^b   Prudencio, Mercedes ^a   Caulfield, Thomas R ^a   Zhang, Yong Jie ^a   Tay, William M ^a   Bauer, Peter O ^a   Chew, Jeannie ^a   Sasaguri, Hiroki ^a   Jansen west, Karen R ^a   Gendron, Tania F ^a   Stetler, Caroline T ^a   Finch, NiCole ^a   Mackenzie, Ian R ^c   Rademakers, Rosa ^a   Gao, Fen Biao ^b   Petrucelli, Leonard ^a  

^a MAYO GRADUATE SCHOOL   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEINS, VESICULAR TRANSPORT; CELL LINE, TUMOR; ENDOCYTOSIS; FRONTOTEMPORAL DEMENTIA; GENETIC VARIATION; HAPLOINSUFFICIENCY; HEK293 CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOCYTES; PYRIDINES; REPRODUCIBILITY OF RESULTS;

EID: 84894298786     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt534     Document Type: Article

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