Pattern of structural and functional brain abnormalities in asymptomatic granulin mutation carriers

Alzheimer's and Dementia

Volumn 10, Issue 5, 2014, Pages S354-S363.e1

  Pievani, Michela ^a   Paternicò, Donata ^a   Benussi, Luisa ^a   Binetti, Giuliano ^a   Orlandini, Alberto ^b   Cobelli, Milena ^b   Magnaldi, Silvia ^b   Ghidoni, Roberta ^a   Frisoni, Giovanni B ^a,c  

^a IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

^b Spedali Civili   (Italy)

^c UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Cortical thickness; Diffusion tensor; FTLD; Magnetic resonance imaging; Progranulin; Resting state functional MRI

Indexed keywords

GRANULIN; GROWTH FACTOR; PROGRANULIN; UNCLASSIFIED DRUG; GRN PROTEIN, HUMAN; SIGNAL PEPTIDE;

ADULT; AGED; ARTICLE; BRAIN ATROPHY; BRAIN CORTEX; BRAIN FUNCTION; CLINICAL ARTICLE; CORTICAL THICKNESS (BRAIN); DIFFUSION TENSOR IMAGING; FEMALE; FRONTAL CORTEX; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENE MUTATION; HUMAN; INDEPENDENT COMPONENT ANALYSIS; MEDIAL LONGITUDINAL FASCICULUS; MIDDLE FRONTAL GYRUS; NUCLEAR MAGNETIC RESONANCE IMAGING; PARIETAL CORTEX; PRIMARY MOTOR CORTEX; PYRAMIDAL TRACT; RESTING STATE NETWORK; SYMPTOM; WHITE MATTER; ATROPHY; BRAIN; CONGENITAL MALFORMATION; GENETICS; HETEROZYGOTE; MIDDLE AGED; MUTATION; NERVE TRACT; ORGAN SIZE; PATHOPHYSIOLOGY; REST;

ADULT; ATROPHY; BRAIN; DIFFUSION TENSOR IMAGING; FEMALE; HETEROZYGOTE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; MUTATION; NEURAL PATHWAYS; ORGAN SIZE; REST; WHITE MATTER;

EID: 84908248761     PISSN: 15525260     EISSN: 15525279     Source Type: Journal    
DOI: 10.1016/j.jalz.2013.09.009     Document Type: Article

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