메뉴 건너뛰기




Volumn 10, Issue , 2009, Pages 130-

Progranulin is expressed within motor neurons and promotes neuronal cell survival

Author keywords

[No Author keywords available]

Indexed keywords

CALRETICULIN; CHROMOGRANIN A; CYTOCHROME C; PROGRANULIN; SYNAPTOPHYSIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; TAR DNA BINDING PROTEIN;

EID: 70749120467     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-10-130     Document Type: Article
Times cited : (136)

References (78)
  • 1
    • 0026580016 scopus 로고
    • Isolation and sequence of the granulin precursor cDNA from human bone marrow reveals tandem cysteine-rich granulin domains
    • 10.1073/pnas.89.5.1715, 48523, 1542665
    • Bhandari V, Palfree RG, Bateman A. Isolation and sequence of the granulin precursor cDNA from human bone marrow reveals tandem cysteine-rich granulin domains. Proc Natl Acad Sci USA 1992, 89(5):1715-1719. 10.1073/pnas.89.5.1715, 48523, 1542665.
    • (1992) Proc Natl Acad Sci USA , vol.89 , Issue.5 , pp. 1715-1719
    • Bhandari, V.1    Palfree, R.G.2    Bateman, A.3
  • 3
    • 0027241980 scopus 로고
    • Purification of an autocrine growth factor homologous with mouse epithelin presursor from a highly tumorigenic cell line
    • Zhou J, Gao G, Crabb JW, Serrero G. Purification of an autocrine growth factor homologous with mouse epithelin presursor from a highly tumorigenic cell line. The Journal of Biological Chemistry 1993, 268:10863-10869.
    • (1993) The Journal of Biological Chemistry , vol.268 , pp. 10863-10869
    • Zhou, J.1    Gao, G.2    Crabb, J.W.3    Serrero, G.4
  • 4
    • 0025248770 scopus 로고
    • Acrosome biogenesis begins during meiosis: evidence from the synthesis and distribution of an acrosomal glycoprotein, acrogranin, during guinea pig spermatogenesis
    • 10.1095/biolreprod42.2.317, 1692485
    • Anakwe OO, Gerton GL. Acrosome biogenesis begins during meiosis: evidence from the synthesis and distribution of an acrosomal glycoprotein, acrogranin, during guinea pig spermatogenesis. Biology of Reproduction 1990, 42:317-328. 10.1095/biolreprod42.2.317, 1692485.
    • (1990) Biology of Reproduction , vol.42 , pp. 317-328
    • Anakwe, O.O.1    Gerton, G.L.2
  • 5
    • 0142063028 scopus 로고    scopus 로고
    • Progranulin (granulin-epithelin precursor, PC-cell derived growth factor, acrogranin) in proliferation and tumorigenesis
    • Ong CH, Bateman A. Progranulin (granulin-epithelin precursor, PC-cell derived growth factor, acrogranin) in proliferation and tumorigenesis. Histology and Histopathology 2003, 18:1275-1288.
    • (2003) Histology and Histopathology , vol.18 , pp. 1275-1288
    • Ong, C.H.1    Bateman, A.2
  • 6
    • 70549109118 scopus 로고    scopus 로고
    • The granulin gene family: from cancer to dementia
    • 10.1002/bies.200900086, 19795409
    • Bateman A, Bennett HPJ. The granulin gene family: from cancer to dementia. BioEssays 2009, 31:1245-1254. 10.1002/bies.200900086, 19795409.
    • (2009) BioEssays , vol.31 , pp. 1245-1254
    • Bateman, A.1    Bennett, H.P.J.2
  • 7
    • 33746910649 scopus 로고    scopus 로고
    • Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21
    • 10.1038/nature05017, 16862115
    • Cruts M, Zee G, Engelborghs S, Wils H, Pirici D, Rademakers R, Vandenberghe R, Dermaut B, Martin J, Duijn C. Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21. Nature 2006, 442:920-924. 10.1038/nature05017, 16862115.
    • (2006) Nature , vol.442 , pp. 920-924
    • Cruts, M.1    Zee, G.2    Engelborghs, S.3    Wils, H.4    Pirici, D.5    Rademakers, R.6    Vandenberghe, R.7    Dermaut, B.8    Martin, J.9    Duijn, C.10
  • 10
    • 34247606414 scopus 로고    scopus 로고
    • TDP-43 immunoreactivity in neuronal inclusions in familial amyotrophic lateral sclerosis with or without SOD1 gene mutation
    • 10.1007/s00401-007-0206-9, 17333220
    • Tan CF, Eguchi H, Tagawa A, Onodera O, Iwasaki T, Tsujino A, Nishizawa M, Kakita A, Takahashi H. TDP-43 immunoreactivity in neuronal inclusions in familial amyotrophic lateral sclerosis with or without SOD1 gene mutation. Acta Neuropathol 2007, 113(5):535-542. 10.1007/s00401-007-0206-9, 17333220.
    • (2007) Acta Neuropathol , vol.113 , Issue.5 , pp. 535-542
    • Tan, C.F.1    Eguchi, H.2    Tagawa, A.3    Onodera, O.4    Iwasaki, T.5    Tsujino, A.6    Nishizawa, M.7    Kakita, A.8    Takahashi, H.9
  • 11
    • 33750716074 scopus 로고    scopus 로고
    • TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
    • 10.1016/j.bbrc.2006.10.093, 17084815
    • Arai T, Hasegawa M, Akiyama H, Ikeda K, Nonaka T, Mori H, Mann D, Tsuchiya K, Yoshida M, Hashizume Y. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem Biophys Res Commun 2006, 351(3):602-611. 10.1016/j.bbrc.2006.10.093, 17084815.
    • (2006) Biochem Biophys Res Commun , vol.351 , Issue.3 , pp. 602-611
    • Arai, T.1    Hasegawa, M.2    Akiyama, H.3    Ikeda, K.4    Nonaka, T.5    Mori, H.6    Mann, D.7    Tsuchiya, K.8    Yoshida, M.9    Hashizume, Y.10
  • 13
    • 34249946466 scopus 로고    scopus 로고
    • Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amytrophic lateral sclerosis with SOD1 mutations
    • 10.1002/ana.21147, 17469116
    • Mackenzie IR, Bigio EH, Ince PG, Geser F, Neumann M, Cairns NJ, Kwong LK, Forman MS, Ravits J, Stewart H. Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amytrophic lateral sclerosis with SOD1 mutations. Ann Neurol 2007, 61(5):427-434. 10.1002/ana.21147, 17469116.
    • (2007) Ann Neurol , vol.61 , Issue.5 , pp. 427-434
    • Mackenzie, I.R.1    Bigio, E.H.2    Ince, P.G.3    Geser, F.4    Neumann, M.5    Cairns, N.J.6    Kwong, L.K.7    Forman, M.S.8    Ravits, J.9    Stewart, H.10
  • 14
    • 37349034999 scopus 로고    scopus 로고
    • Evidence that TDP-43 is not the major ubiquitinated target within the pathological inclusions of amyotrophic lateral sclerosis
    • 10.1097/nen.0b013e31815c5edd, 18090923
    • Sanelli T, Xiao S, Horne P, Bilbao J, Zinman L, Robertson J. Evidence that TDP-43 is not the major ubiquitinated target within the pathological inclusions of amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 2007, 66(12):1147-1153. 10.1097/nen.0b013e31815c5edd, 18090923.
    • (2007) J Neuropathol Exp Neurol , vol.66 , Issue.12 , pp. 1147-1153
    • Sanelli, T.1    Xiao, S.2    Horne, P.3    Bilbao, J.4    Zinman, L.5    Robertson, J.6
  • 15
    • 58049221032 scopus 로고    scopus 로고
    • Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: implications for TDP-43 in the physiological response to neuronal injury
    • 10.1016/j.brainres.2008.10.021, 19046946
    • Moisse K, Volkening K, Leystra-Lantz C, Welch I, Hill T, Strong MJ. Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: implications for TDP-43 in the physiological response to neuronal injury. Brain Res 2009, 1249:202-211. 10.1016/j.brainres.2008.10.021, 19046946.
    • (2009) Brain Res , vol.1249 , pp. 202-211
    • Moisse, K.1    Volkening, K.2    Leystra-Lantz, C.3    Welch, I.4    Hill, T.5    Strong, M.J.6
  • 17
    • 38349173569 scopus 로고    scopus 로고
    • Missense mutations in the progranulin gene linked to frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions reduce progranulin production and secretion
    • 10.1074/jbc.M705115200, 17984093
    • Shankaran SS, Capell A, Hruscha AT, Fellerer K, Neumann M, Schmid B, Haass C. Missense mutations in the progranulin gene linked to frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions reduce progranulin production and secretion. J Biol Chem 2008, 283:1744-1753. 10.1074/jbc.M705115200, 17984093.
    • (2008) J Biol Chem , vol.283 , pp. 1744-1753
    • Shankaran, S.S.1    Capell, A.2    Hruscha, A.T.3    Fellerer, K.4    Neumann, M.5    Schmid, B.6    Haass, C.7
  • 18
    • 67650432367 scopus 로고    scopus 로고
    • Proteolytic processing of TAR DNA binding protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin
    • 10.1111/j.1471-4159.2009.06211.x, 19522733
    • Dormann D, Capell A, Carlson AM, Shankaran SS, Rodde R, Neumann M, Kremmer E, Matsuwaki T, Yamanouchi K, Nishihara M. Proteolytic processing of TAR DNA binding protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin. J Neurochem 2009, 110(3):1082-1094. 10.1111/j.1471-4159.2009.06211.x, 19522733.
    • (2009) J Neurochem , vol.110 , Issue.3 , pp. 1082-1094
    • Dormann, D.1    Capell, A.2    Carlson, A.M.3    Shankaran, S.S.4    Rodde, R.5    Neumann, M.6    Kremmer, E.7    Matsuwaki, T.8    Yamanouchi, K.9    Nishihara, M.10
  • 19
    • 70749151364 scopus 로고    scopus 로고
    • NIH Symposium on Progranulin and the TDP-43 Proteinopathies. NINDS Workshop and Conference Proceedings 2008
    • NIH Symposium on Progranulin and the TDP-43 Proteinopathies. NINDS Workshop and Conference Proceedings 2008. , http://www.ninds.nih.gov/news_and_events/proceedings/NIH_Symposium_on_Pr ogranulin_and_the_TDP-43_Proteinopathies.htm
  • 21
    • 0042635680 scopus 로고    scopus 로고
    • Progranulin (acrogranin/PC cell-derived growth factor/granulin-epithelin precursor) is expressed in the placenta, epidermis, microvasculature, and brain during murine development
    • 10.1002/dvdy.10341, 12889069
    • Daniel R, Daniels E, He Z, Bateman A. Progranulin (acrogranin/PC cell-derived growth factor/granulin-epithelin precursor) is expressed in the placenta, epidermis, microvasculature, and brain during murine development. Dev Dyn 2003, 227(4):593-599. 10.1002/dvdy.10341, 12889069.
    • (2003) Dev Dyn , vol.227 , Issue.4 , pp. 593-599
    • Daniel, R.1    Daniels, E.2    He, Z.3    Bateman, A.4
  • 22
    • 0032548759 scopus 로고    scopus 로고
    • Identification of a sex steroid-inducible gene in the neonatal rat hypothalamus
    • 10.1016/S0304-3940(98)00008-1, 9530922
    • Suzuki M, Yoshida S, Nishihara M, Takahashi M. Identification of a sex steroid-inducible gene in the neonatal rat hypothalamus. Neuroscience Letters 1998, 242:127-130. 10.1016/S0304-3940(98)00008-1, 9530922.
    • (1998) Neuroscience Letters , vol.242 , pp. 127-130
    • Suzuki, M.1    Yoshida, S.2    Nishihara, M.3    Takahashi, M.4
  • 23
    • 0034068419 scopus 로고    scopus 로고
    • Suppression of copulatory behavior by intracerebroventricular infusion of antisense oligodeoxynucleotide of granulin in neonatal male rats
    • 10.1016/S0031-9384(99)00241-3, 10764901
    • Suzuki M, Bannai M, Matsumuro M, Furuhata Y, Ikemura R, Kuranaga E, Kaneda Y, Nishihara M, Takahashi M. Suppression of copulatory behavior by intracerebroventricular infusion of antisense oligodeoxynucleotide of granulin in neonatal male rats. Physiology & Behavior 2000, 68:707-713. 10.1016/S0031-9384(99)00241-3, 10764901.
    • (2000) Physiology & Behavior , vol.68 , pp. 707-713
    • Suzuki, M.1    Bannai, M.2    Matsumuro, M.3    Furuhata, Y.4    Ikemura, R.5    Kuranaga, E.6    Kaneda, Y.7    Nishihara, M.8    Takahashi, M.9
  • 24
    • 34248393103 scopus 로고    scopus 로고
    • Involvement of granulin in estrogen-induced neurogenesis in the adult rat hippocampus
    • 10.1262/jrd.18108, 17179653
    • Chiba S, Suzuki M, Yamanouchi K, Nishihara M. Involvement of granulin in estrogen-induced neurogenesis in the adult rat hippocampus. J Reprod Dev 2007, 53(2):297-307. 10.1262/jrd.18108, 17179653.
    • (2007) J Reprod Dev , vol.53 , Issue.2 , pp. 297-307
    • Chiba, S.1    Suzuki, M.2    Yamanouchi, K.3    Nishihara, M.4
  • 25
    • 42049087853 scopus 로고    scopus 로고
    • Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival
    • 2287280, 18378771, 10.1083/jcb.200712039
    • Van Damme P, Van Hoecke A, Lambrechts D, Vanacker P, Bogaert E, van Swieten J, Carmeliet P, Bosch L, Robberecht W. Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival. J Cell Biol 2008, 181(1):37-41. 2287280, 18378771, 10.1083/jcb.200712039.
    • (2008) J Cell Biol , vol.181 , Issue.1 , pp. 37-41
    • Van Damme, P.1    Van Hoecke, A.2    Lambrechts, D.3    Vanacker, P.4    Bogaert, E.5    van Swieten, J.6    Carmeliet, P.7    Bosch, L.8    Robberecht, W.9
  • 26
    • 0036792137 scopus 로고    scopus 로고
    • Progranulin (PC-cell-derived growth factor/acrogranin) regulates invasion and cell survival
    • He Z, Ismail A, Kriazhev L, Sadvakassova G, Bateman A. Progranulin (PC-cell-derived growth factor/acrogranin) regulates invasion and cell survival. Cancer Research 2002, 62:5590-5596.
    • (2002) Cancer Research , vol.62 , pp. 5590-5596
    • He, Z.1    Ismail, A.2    Kriazhev, L.3    Sadvakassova, G.4    Bateman, A.5
  • 27
    • 0035793102 scopus 로고    scopus 로고
    • Mediation of estrogen mitogenic effect in human breast cancer MCF-7 cells by PC-cell-derived growth factor (PCDGF/granulin precursor)
    • 14558, 11134521, 10.1073/pnas.011525198
    • Lu R, Serrero G. Mediation of estrogen mitogenic effect in human breast cancer MCF-7 cells by PC-cell-derived growth factor (PCDGF/granulin precursor). Proceedings of the National Academy of Sciences of the United States of America 2001, 98:142-147. 14558, 11134521, 10.1073/pnas.011525198.
    • (2001) Proceedings of the National Academy of Sciences of the United States of America , vol.98 , pp. 142-147
    • Lu, R.1    Serrero, G.2
  • 30
    • 0344586759 scopus 로고    scopus 로고
    • Expression of PC-cell-derived growth factor in benign and malignant human breast epithelium
    • 10.1016/S0046-8177(03)00425-8, 14652816
    • Serrero G, Ioffe OB. Expression of PC-cell-derived growth factor in benign and malignant human breast epithelium. Human Pathology 2003, 34:1148-1154. 10.1016/S0046-8177(03)00425-8, 14652816.
    • (2003) Human Pathology , vol.34 , pp. 1148-1154
    • Serrero, G.1    Ioffe, O.B.2
  • 34
    • 33746865874 scopus 로고    scopus 로고
    • Proepithelin promotes migration and invasion of 5637 bladder cancer cells through activation of ERK1/2 and the formation of a paxillin/FAK/ERK complex
    • 10.1158/0008-5472.CAN-06-0633, 16849556
    • Monami G, Gonzalez EM, Hellman M, Gomella LG, Baffa R, Iozzo RV, Morrione A. Proepithelin promotes migration and invasion of 5637 bladder cancer cells through activation of ERK1/2 and the formation of a paxillin/FAK/ERK complex. Cancer Research 2006, 66:7103-7110. 10.1158/0008-5472.CAN-06-0633, 16849556.
    • (2006) Cancer Research , vol.66 , pp. 7103-7110
    • Monami, G.1    Gonzalez, E.M.2    Hellman, M.3    Gomella, L.G.4    Baffa, R.5    Iozzo, R.V.6    Morrione, A.7
  • 35
    • 9344229795 scopus 로고    scopus 로고
    • Granulin-epithelin precursor overexpression promotes growth and invasion of hepatocellular carcinoma
    • 10.1158/1078-0432.CCR-04-0960, 15569995
    • Cheung ST, Wong SY, Leung KL, Chen X, So S, Ng IO, Fan ST. Granulin-epithelin precursor overexpression promotes growth and invasion of hepatocellular carcinoma. Clinical Cancer Research 2004, 10:7629-7636. 10.1158/1078-0432.CCR-04-0960, 15569995.
    • (2004) Clinical Cancer Research , vol.10 , pp. 7629-7636
    • Cheung, S.T.1    Wong, S.Y.2    Leung, K.L.3    Chen, X.4    So, S.5    Ng, I.O.6    Fan, S.T.7
  • 38
    • 33645047659 scopus 로고    scopus 로고
    • Oncogenic property of acrogranin in human uterine leiomyosarcoma: direct evidence of genetic contribution in in vivo tumorigenesis
    • 10.1158/1078-0432.CCR-05-2003, 16533762
    • Matsumura N, Mandai M, Miyanishi M, Fukuhara K, Baba T, Higuchi T, Kariya M, Takakura K, Fujii S. Oncogenic property of acrogranin in human uterine leiomyosarcoma: direct evidence of genetic contribution in in vivo tumorigenesis. Clinical Cancer Research 2006, 12:1402-1411. 10.1158/1078-0432.CCR-05-2003, 16533762.
    • (2006) Clinical Cancer Research , vol.12 , pp. 1402-1411
    • Matsumura, N.1    Mandai, M.2    Miyanishi, M.3    Fukuhara, K.4    Baba, T.5    Higuchi, T.6    Kariya, M.7    Takakura, K.8    Fujii, S.9
  • 39
    • 0038514929 scopus 로고    scopus 로고
    • PC cell-derived growth factor (granulin precursor) expression and action in human multiple myeloma
    • Wang W, Hayashi J, Kim WE, Serrero G. PC cell-derived growth factor (granulin precursor) expression and action in human multiple myeloma. Clinical Cancer Research 2003, 9:2221-2228.
    • (2003) Clinical Cancer Research , vol.9 , pp. 2221-2228
    • Wang, W.1    Hayashi, J.2    Kim, W.E.3    Serrero, G.4
  • 40
    • 0037329891 scopus 로고    scopus 로고
    • Progranulin is a mediator of the wound response
    • 10.1038/nm816, 12524533
    • He Z, Ong CH, Halper J, Bateman A. Progranulin is a mediator of the wound response. Nature Medicine 2003, 9:225-229. 10.1038/nm816, 12524533.
    • (2003) Nature Medicine , vol.9 , pp. 225-229
    • He, Z.1    Ong, C.H.2    Halper, J.3    Bateman, A.4
  • 43
    • 0037074016 scopus 로고    scopus 로고
    • Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair
    • 10.1016/S0092-8674(02)01141-8, 12526812
    • Zhu J, Nathan C, Jin W, Sim D, Ashcroft GS, Wahl SM, Lacomis L, Erdjument-Bromage H, Tempst P, Wright CD. Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair. Cell 2002, 111(6):867-878. 10.1016/S0092-8674(02)01141-8, 12526812.
    • (2002) Cell , vol.111 , Issue.6 , pp. 867-878
    • Zhu, J.1    Nathan, C.2    Jin, W.3    Sim, D.4    Ashcroft, G.S.5    Wahl, S.M.6    Lacomis, L.7    Erdjument-Bromage, H.8    Tempst, P.9    Wright, C.D.10
  • 44
    • 27944504300 scopus 로고    scopus 로고
    • The zebrafish progranulin gene family and antisense transcripts
    • 1310530, 16277664, 10.1186/1471-2164-6-156
    • Cadieux B, Chitramuthu BP, Baranowski D, Bennett HP. The zebrafish progranulin gene family and antisense transcripts. BMC Genomics 2005, 6:156. 1310530, 16277664, 10.1186/1471-2164-6-156.
    • (2005) BMC Genomics , vol.6 , pp. 156
    • Cadieux, B.1    Chitramuthu, B.P.2    Baranowski, D.3    Bennett, H.P.4
  • 45
    • 0342980940 scopus 로고    scopus 로고
    • Modulation of mouse preimplantation embryo development by acrogranin (epithelin/granulin precursor)
    • 10.1006/dbio.1999.9564, 10625564
    • Diaz-Cueto L, Stein P, Jacobs A, Schultz RM, Gerton GL. Modulation of mouse preimplantation embryo development by acrogranin (epithelin/granulin precursor). Developmental Biology 2000, 217:406-418. 10.1006/dbio.1999.9564, 10625564.
    • (2000) Developmental Biology , vol.217 , pp. 406-418
    • Diaz-Cueto, L.1    Stein, P.2    Jacobs, A.3    Schultz, R.M.4    Gerton, G.L.5
  • 47
    • 0035085455 scopus 로고    scopus 로고
    • Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays
    • Malaspina A, Kaushik N, de Belleroche J. Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays. J Neurochem 2001, 77(1):132-145.
    • (2001) J Neurochem , vol.77 , Issue.1 , pp. 132-145
    • Malaspina, A.1    Kaushik, N.2    de Belleroche, J.3
  • 48
    • 58149147341 scopus 로고    scopus 로고
    • Progranulin (PGRN) expression in ALS: An immunohistochemical study
    • 10.1016/j.jns.2008.08.024, 18848708
    • Irwin D, Lippa CF, Rosso A. Progranulin (PGRN) expression in ALS: An immunohistochemical study. J Neurol Sci 2008, 276(1-2):9-13. 10.1016/j.jns.2008.08.024, 18848708.
    • (2008) J Neurol Sci , vol.276 , Issue.1-2 , pp. 9-13
    • Irwin, D.1    Lippa, C.F.2    Rosso, A.3
  • 49
    • 34250656185 scopus 로고    scopus 로고
    • Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons
    • 1863491, 17463094, 10.1073/pnas.0702230104
    • Lobsinger CS, Boillee S, Cleveland DW. Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons. PNAS 2007, 104(18):7319-7326. 1863491, 17463094, 10.1073/pnas.0702230104.
    • (2007) PNAS , vol.104 , Issue.18 , pp. 7319-7326
    • Lobsinger, C.S.1    Boillee, S.2    Cleveland, D.W.3
  • 50
    • 34548157024 scopus 로고    scopus 로고
    • Microarray analysis of the cellular pathways involved in the adaptation to and progression of motor neuron injury in the SOD1 G93A mouse model of familial ALS
    • 10.1523/JNEUROSCI.1470-07.2007, 17715356
    • Ferraiuolo L, Heath PR, Holden H, Kasher P, Kirby J, Shaw PJ. Microarray analysis of the cellular pathways involved in the adaptation to and progression of motor neuron injury in the SOD1 G93A mouse model of familial ALS. J Neurosci 2007, 27(34):9201-9219. 10.1523/JNEUROSCI.1470-07.2007, 17715356.
    • (2007) J Neurosci , vol.27 , Issue.34 , pp. 9201-9219
    • Ferraiuolo, L.1    Heath, P.R.2    Holden, H.3    Kasher, P.4    Kirby, J.5    Shaw, P.J.6
  • 54
    • 39749187585 scopus 로고    scopus 로고
    • Frequency and clinical characteristics of progranulin mutation carriers in the Manchester frontotemporal lobar degeneration cohort: comparison with patients with MAPT and no known mutations
    • 10.1093/brain/awm331, 18192287
    • Pickering-Brown SM, Rollinson S, Du Plessis D, Morrison KE, Varma A, Richardson AM, Neary D, Snowden JS, Mann DM. Frequency and clinical characteristics of progranulin mutation carriers in the Manchester frontotemporal lobar degeneration cohort: comparison with patients with MAPT and no known mutations. Brain 2008, 131(Pt 3):721-731. 10.1093/brain/awm331, 18192287.
    • (2008) Brain , vol.131 , Issue.PART 3 , pp. 721-731
    • Pickering-Brown, S.M.1    Rollinson, S.2    Du Plessis, D.3    Morrison, K.E.4    Varma, A.5    Richardson, A.M.6    Neary, D.7    Snowden, J.S.8    Mann, D.M.9
  • 56
    • 0035676020 scopus 로고    scopus 로고
    • The evidence for ALS as a multisystems disorder of limited phenotypic expression
    • Strong MJ. The evidence for ALS as a multisystems disorder of limited phenotypic expression. Can J Neurol Sci 2001, 28:283-298.
    • (2001) Can J Neurol Sci , vol.28 , pp. 283-298
    • Strong, M.J.1
  • 57
    • 37349063722 scopus 로고    scopus 로고
    • The neuropathology of FTD associated with ALS
    • 10.1097/WAD.0b013e31815c3486, 18090423
    • Mackenzie IR. The neuropathology of FTD associated with ALS. Alzheimer Dis Assoc Disord 2007, 21:S44-49. 10.1097/WAD.0b013e31815c3486, 18090423.
    • (2007) Alzheimer Dis Assoc Disord , vol.21
    • Mackenzie, I.R.1
  • 60
    • 34447097449 scopus 로고    scopus 로고
    • The neuropathology and clinical phenotype of FTD with progranulin mutations
    • 10.1007/s00401-007-0223-8, 17458552
    • Mackenzie IR. The neuropathology and clinical phenotype of FTD with progranulin mutations. Acta Neuropathol 2007, 114(1):49-54. 10.1007/s00401-007-0223-8, 17458552.
    • (2007) Acta Neuropathol , vol.114 , Issue.1 , pp. 49-54
    • Mackenzie, I.R.1
  • 62
    • 33846221802 scopus 로고    scopus 로고
    • Vascular endothelial growth factor overexpression delays neurodegeneration and prolongs survival in amyotrophic lateral sclerosis mice
    • 10.1523/JNEUROSCI.4433-06.2007, 17215390
    • Wang Y, Mao XO, Xie L, Banwait S, Marti HH, Greenberg DA, Jin K. Vascular endothelial growth factor overexpression delays neurodegeneration and prolongs survival in amyotrophic lateral sclerosis mice. J Neurosci 2007, 27(2):304-307. 10.1523/JNEUROSCI.4433-06.2007, 17215390.
    • (2007) J Neurosci , vol.27 , Issue.2 , pp. 304-307
    • Wang, Y.1    Mao, X.O.2    Xie, L.3    Banwait, S.4    Marti, H.H.5    Greenberg, D.A.6    Jin, K.7
  • 63
    • 0042528664 scopus 로고    scopus 로고
    • Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model
    • 10.1126/science.1086137, 12907804
    • Kaspar BK, Llado J, Sherkat N, Rothstein JD, Gage FH. Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model. Science 2003, 301(5634):839-842. 10.1126/science.1086137, 12907804.
    • (2003) Science , vol.301 , Issue.5634 , pp. 839-842
    • Kaspar, B.K.1    Llado, J.2    Sherkat, N.3    Rothstein, J.D.4    Gage, F.H.5
  • 64
    • 0032402093 scopus 로고    scopus 로고
    • Glutamate potentiates the toxicity of mutant Cu/Zn-superoxide dismutase in motor neurons by postsynaptic calcium-dependent mechanisms
    • Roy J, Minotti S, Dong L, Figlewicz DA, Durham HD. Glutamate potentiates the toxicity of mutant Cu/Zn-superoxide dismutase in motor neurons by postsynaptic calcium-dependent mechanisms. J Neurosci 1998, 18(23):9673-9684.
    • (1998) J Neurosci , vol.18 , Issue.23 , pp. 9673-9684
    • Roy, J.1    Minotti, S.2    Dong, L.3    Figlewicz, D.A.4    Durham, H.D.5
  • 66
    • 0027714989 scopus 로고
    • Evaluation of the spinal cord neuron X neuroblastoma hybrid cell line NSC-34 as a model for neurotoxicity testing
    • Durham HD, Dahrouge S, Cashman NR. Evaluation of the spinal cord neuron X neuroblastoma hybrid cell line NSC-34 as a model for neurotoxicity testing. Neurotoxicology 1993, 14(4):387-395.
    • (1993) Neurotoxicology , vol.14 , Issue.4 , pp. 387-395
    • Durham, H.D.1    Dahrouge, S.2    Cashman, N.R.3
  • 67
    • 36048985104 scopus 로고    scopus 로고
    • SMN protects cells against mutant SOD1 toxicity by increasing chaperone activity
    • 2169267, 17964281, 10.1016/j.bbrc.2007.10.096
    • Zou T, Ilangovan R, Yu F, Xu Z, Zhou J. SMN protects cells against mutant SOD1 toxicity by increasing chaperone activity. Biochem Biophys Res Commun 2007, 364(4):850-855. 2169267, 17964281, 10.1016/j.bbrc.2007.10.096.
    • (2007) Biochem Biophys Res Commun , vol.364 , Issue.4 , pp. 850-855
    • Zou, T.1    Ilangovan, R.2    Yu, F.3    Xu, Z.4    Zhou, J.5
  • 68
    • 35848946825 scopus 로고    scopus 로고
    • P38alpha MAP kinase mediates hypoxia-induced motor neuron cell death: a potential target of minocycline's neuroprotective action
    • 10.1007/s11064-007-9408-8, 17594516
    • Guo G, Bhat NR. p38alpha MAP kinase mediates hypoxia-induced motor neuron cell death: a potential target of minocycline's neuroprotective action. Neurochem Res 2007, 32(12):2160-2166. 10.1007/s11064-007-9408-8, 17594516.
    • (2007) Neurochem Res , vol.32 , Issue.12 , pp. 2160-2166
    • Guo, G.1    Bhat, N.R.2
  • 69
    • 34347222588 scopus 로고    scopus 로고
    • The nuclear factor kappaB-activator gene PLEKHG5 is mutated in a form of autosomal recessive lower motor neuron disease with childhood onset
    • 1950913, 17564964, 10.1086/518900
    • Maystadt I, Rezsohazy R, Barkats M, Duque S, Vannuffel P, Remacle S, Lambert B, Najimi M, Sokal E, Munnich A. The nuclear factor kappaB-activator gene PLEKHG5 is mutated in a form of autosomal recessive lower motor neuron disease with childhood onset. Am J Hum Genet 2007, 81(1):67-76. 1950913, 17564964, 10.1086/518900.
    • (2007) Am J Hum Genet , vol.81 , Issue.1 , pp. 67-76
    • Maystadt, I.1    Rezsohazy, R.2    Barkats, M.3    Duque, S.4    Vannuffel, P.5    Remacle, S.6    Lambert, B.7    Najimi, M.8    Sokal, E.9    Munnich, A.10
  • 70
    • 34249679116 scopus 로고    scopus 로고
    • P62 accumulates and enhances aggregate formation in model systems of familial amyotrophic lateral sclerosis
    • 10.1074/jbc.M608787200, 17296612
    • Gal J, Strom AL, Kilty R, Zhang F, Zhu H. p62 accumulates and enhances aggregate formation in model systems of familial amyotrophic lateral sclerosis. J Biol Chem 2007, 282(15):11068-11077. 10.1074/jbc.M608787200, 17296612.
    • (2007) J Biol Chem , vol.282 , Issue.15 , pp. 11068-11077
    • Gal, J.1    Strom, A.L.2    Kilty, R.3    Zhang, F.4    Zhu, H.5
  • 71
    • 33845773367 scopus 로고    scopus 로고
    • Depletion of reduced glutathione enhances motor neuron degeneration in vitro and in vivo
    • 1944995, 17150307, 10.1016/j.neuroscience.2006.09.064
    • Chi L, Ke Y, Luo C, Gozal D, Liu R. Depletion of reduced glutathione enhances motor neuron degeneration in vitro and in vivo. Neuroscience 2007, 144(3):991-1003. 1944995, 17150307, 10.1016/j.neuroscience.2006.09.064.
    • (2007) Neuroscience , vol.144 , Issue.3 , pp. 991-1003
    • Chi, L.1    Ke, Y.2    Luo, C.3    Gozal, D.4    Liu, R.5
  • 72
    • 14244264186 scopus 로고    scopus 로고
    • A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death
    • 10.1074/jbc.M410508200, 15579468
    • Kanekura K, Hashimoto Y, Kita Y, Sasabe J, Aiso S, Nishimoto I, Matsuoka M. A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death. J Biol Chem 2005, 280(6):4532-4543. 10.1074/jbc.M410508200, 15579468.
    • (2005) J Biol Chem , vol.280 , Issue.6 , pp. 4532-4543
    • Kanekura, K.1    Hashimoto, Y.2    Kita, Y.3    Sasabe, J.4    Aiso, S.5    Nishimoto, I.6    Matsuoka, M.7
  • 73
    • 0034048839 scopus 로고    scopus 로고
    • Development and characterisation of a glutamate-sensitive motor neurone cell line
    • 10.1046/j.1471-4159.2000.0741895.x, 10800932
    • Eggett CJ, Crosier S, Manning P, Cookson MR, Menzies FM, McNeil CJ, Shaw PJ. Development and characterisation of a glutamate-sensitive motor neurone cell line. J Neurochem 2000, 74(5):1895-1902. 10.1046/j.1471-4159.2000.0741895.x, 10800932.
    • (2000) J Neurochem , vol.74 , Issue.5 , pp. 1895-1902
    • Eggett, C.J.1    Crosier, S.2    Manning, P.3    Cookson, M.R.4    Menzies, F.M.5    McNeil, C.J.6    Shaw, P.J.7
  • 74
    • 0025547555 scopus 로고
    • Granulins, a novel class of peptide from leukocytes
    • 10.1016/S0006-291X(05)80908-8, 2268320
    • Bateman A, Belcourt D, Bennett H, Lazure C, Solomon S. Granulins, a novel class of peptide from leukocytes. Biochem Biophys Res Commun 1990, 173(3):1161-1168. 10.1016/S0006-291X(05)80908-8, 2268320.
    • (1990) Biochem Biophys Res Commun , vol.173 , Issue.3 , pp. 1161-1168
    • Bateman, A.1    Belcourt, D.2    Bennett, H.3    Lazure, C.4    Solomon, S.5
  • 75
    • 0037371643 scopus 로고    scopus 로고
    • The growth factor granulin interacts with cyclin T1 and modulates P-TEFb-dependent transcription
    • 151712, 12588988, 10.1128/MCB.23.5.1688-1702.2003
    • Hoque M, Young TM, Lee CG, Serrero G, Mathews MB, Pe'ery T. The growth factor granulin interacts with cyclin T1 and modulates P-TEFb-dependent transcription. Mol Cell Biol 2003, 23:1688-1702. 151712, 12588988, 10.1128/MCB.23.5.1688-1702.2003.
    • (2003) Mol Cell Biol , vol.23 , pp. 1688-1702
    • Hoque, M.1    Young, T.M.2    Lee, C.G.3    Serrero, G.4    Mathews, M.B.5    Pe'ery, T.6
  • 76
    • 37549049344 scopus 로고    scopus 로고
    • Progranulin is a stress-response factor in fibroblasts subjected to hypoxia and acidosis
    • 10.1080/08977190701781222, 18092235
    • Guerra RR, Kriazhev L, Hernandez-Blazquez FJ, Bateman A. Progranulin is a stress-response factor in fibroblasts subjected to hypoxia and acidosis. Growth Factors 2007, 25(4):280-285. 10.1080/08977190701781222, 18092235.
    • (2007) Growth Factors , vol.25 , Issue.4 , pp. 280-285
    • Guerra, R.R.1    Kriazhev, L.2    Hernandez-Blazquez, F.J.3    Bateman, A.4
  • 77
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • 55695, 11328886, 10.1093/nar/29.9.e45
    • Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001, 29(9):e45. 55695, 11328886, 10.1093/nar/29.9.e45.
    • (2001) Nucleic Acids Res , vol.29 , Issue.9
    • Pfaffl, M.W.1
  • 78
    • 0033168521 scopus 로고    scopus 로고
    • Progranulin gene expression regulates epithelial cell growth and promotes tumor growth in vivo
    • He Z, Bateman A. Progranulin gene expression regulates epithelial cell growth and promotes tumor growth in vivo. Cancer Res 1999, 59(13):3222-3229.
    • (1999) Cancer Res , vol.59 , Issue.13 , pp. 3222-3229
    • He, Z.1    Bateman, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.