Selective Vulnerability of Cancer Cells by Inhibition of Ca2+ Transfer from Endoplasmic Reticulum to Mitochondria

Cell Reports

Volumn 14, Issue 10, 2016, Pages 2313-2324

  Cárdenas, César ^a   Müller, Marioly ^b   McNeal, Andrew ^c   Lovy, Alenka ^d   Jaňa, Fabian ^a   Bustos, Galdo ^a   Urra, Felix ^a   Smith, Natalia ^a   Molgó, Jordi ^e   Diehl, J Alan ^f,g   Ridky, Todd W ^c   Foskett, J Kevin ^f  

^a Universidad de Chile and Geroscience Center for Brain Health and Metabolism   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e SERVICE DE CHIMIE BIOORGANIQUE ET DE MARQUAGE   (France)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

^g MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; NUCLEOTIDE; ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENT; CALCIUM; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; MACROCYCLIC COMPOUND; MTOR PROTEIN, HUMAN; OXAZOLE DERIVATIVE; SMALL INTERFERING RNA; TARGET OF RAPAMYCIN KINASE; XESTOSPONGIN B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BIOENERGY; CALCIUM TRANSPORT; CANCER CELL; CELL DEATH; CELL METABOLISM; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FIBROBLAST; HUMAN; HUMAN CELL; IN VIVO STUDY; INTRACELLULAR TRANSPORT; MITOCHONDRION; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; GENETICS; METABOLISM; PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR CELL LINE; VIDEO MICROSCOPY; WESTERN BLOTTING;

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; AMP-ACTIVATED PROTEIN KINASES; ANTINEOPLASTIC AGENTS; AUTOPHAGY; BLOTTING, WESTERN; CALCIUM; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MACROCYCLIC COMPOUNDS; MICROSCOPY, VIDEO; MITOCHONDRIA; OXAZOLES; PHOSPHORYLATION; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84960335531     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.02.030     Document Type: Article

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