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Bioorganic and Medicinal Chemistry

Volumn 24, Issue 8, 2016, Pages 1665-1674

In vivo phase II-enzymes inducers, as potential chemopreventive agents, based on the chalcone and furoxan skeletons

(5) Cabrera, Mauricio a Mastandrea, Ignacio a,b Otero, Gabriel a,b Cerecetto, Hugo a González, Mercedes a

a UNIVERSIDAD DE LA REPÚBLICA (Uruguay)

b INSTITUTO DE INVESTIGACIONES BIOLÓGICAS CLEMENTE ESTABLE (Uruguay)

Author keywords

Cancer; Chalcone; Chemoprevention; Furoxan; Phase II enzymes

Indexed keywords

1 (2 HYDROXYPHENYL) 3 (3 METHYLFUROXAN 4 YL) 2 PROPENONE; 1 (2 HYDROXYPHENYL) 3 (4 PHENYLFUROXAN 3 YL) 2 PROPENONE; 1 (2 NAPHTHYL) 3 (4 PHENYLFUROXAN 3 YL) 2 PROPENONE; 1 PHENYL 3 (4 PHENYLFUROXAN 3 YL) 2 PROPENONE; 3 (3 METHYLFUROXAN 4 YL) 1 (2 NAPHTHYL) 2 PROPENONE; 3 (3 METHYLFUROXAN 4 YL) 1 PHENYL 2 PROPENONE; 3 (BENZOFUROXAN 5 YL) 1 (2 HYDROXYPHENYL) 2 PROPENONE; 3 (BENZOFUROXAN 5 YL) 1 (2 NAPHTHYL) 2 PROPENONE; 3 (BENZOFUROXAN 5 YL) 1 PHENYL 2 PROPENONE; ANTINEOPLASTIC AGENT; CHALCONE DERIVATIVE; UNCLASSIFIED DRUG; 1,2,5-OXADIAZOLE 2-OXIDE; CHALCONE; CYTOCHROME P450; GLUTATHIONE TRANSFERASE; OXADIAZOLE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

AMES TEST; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER INHIBITION; COLON CANCER; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ACTIVITY; FEMALE; HT 29 CELL LINE; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE; IN VITRO STUDY; IN VIVO STUDY; LIVER CANCER; MCF 7 CELL LINE; MOUSE; MUTAGENICITY; NONHUMAN; PRECANCER; PROTEIN EXPRESSION; RAT; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; ANIMAL; CELL PROLIFERATION; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; ENZYME INDUCTION; HT-29 CELL LINE; MCF-7 CELL LINE; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL CULTURE; WISTAR RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; CELL SURVIVAL; CHALCONE; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INDUCTION; FEMALE; GLUTATHIONE TRANSFERASE; HT29 CELLS; HUMANS; MCF-7 CELLS; MOLECULAR STRUCTURE; NAD(P)H DEHYDROGENASE (QUINONE); OXADIAZOLES; RATS; RATS, WISTAR; SALMONELLA TYPHIMURIUM; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 84960194289 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2016.02.041 Document Type: Article

Times cited : (20)

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