MLL-AF9-and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C

Journal of Clinical Investigation

Volumn 126, Issue 3, 2016, Pages 997-1011

  Zhu, Nan ^a,b   Chen, Mo ^c   Eng, Rowena ^a   DeJong, Joshua ^b   Sinha, Amit U ^a   Rahnamay, Noushin F ^a   Koche, Richard ^a   Al Shahrour, Fatima ^d   Minehart, Janna C ^a   Chen, Chun Wei ^a   Deshpande, Aniruddha J ^a   Xu, Haiming ^a   Chu, S Haihua ^a   Ebert, Benjamin L ^d   Roeder, Robert G ^c   Armstrong, Scott A ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b BLOOD RESEARCH INSTITUTE   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; GENOMIC DNA; JMJD1C PROTEIN; PROTEIN; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR HOXA9; UNCLASSIFIED DRUG; HISTONE DEMETHYLASE; HOMEODOMAIN PROTEIN; JMJD1C PROTEIN, MOUSE; MLL-AF9 FUSION PROTEIN, MOUSE; ONCOPROTEIN;

ACUTE MYELOBLASTIC LEUKEMIA; ANEMIA; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HEMATOPOIESIS; HUMAN; HUMAN CELL; LEUKEMOGENESIS; LEUKOCYTOSIS; MACROPHAGE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STEM CELL SELF-RENEWAL; THROMBOCYTOPENIA; ACUTE MYELOID LEUKEMIA; ANIMAL; CANCER STEM CELL; CANCER TRANSPLANTATION; CELL SELF-RENEWAL; GENETICS; HEMATOPOIETIC STEM CELL; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL CULTURE;

ANIMALS; CELL SELF RENEWAL; GENE EXPRESSION; HEMATOPOIETIC STEM CELLS; HOMEODOMAIN PROTEINS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; LEUKEMIA, MYELOID, ACUTE; MICE, KNOCKOUT; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; ONCOGENE PROTEINS, FUSION; TUMOR CELLS, CULTURED;

EID: 84959925256     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI82978     Document Type: Article

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