Dietary apigenin exerts immune-regulatory activity in vivo by reducing NF-κB activity, halting leukocyte infiltration and restoring normal metabolic function

International Journal of Molecular Sciences

Volumn 17, Issue 3, 2016, Pages

  Cardenas, Horacio ^a   Arango, Daniel ^a   Nicholas, Courtney ^a   Duarte, Silvia ^a   Nuovo, Gerard J ^b   He, Wei ^a,b   Voss, Oliver H ^a   Gonzalez Mejia, M Elba ^a   Guttridge, Denis C ^b   Grotewold, Erich ^a   Doseff, Andrea I ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Apigenin; Apoptosis; Cardiac dysfunction; Flavonoids; Inflammation; Leukocytes; Mitochondria; NF B; Sepsis

Indexed keywords

APIGENIN; CASPASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ANTIINFLAMMATORY AGENT; LIPOPOLYSACCHARIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HEART FAILURE; IMMUNOHISTOCHEMISTRY; IMMUNOREGULATION; INFLAMMATION; LUCIFERASE ASSAY; LUNG LAVAGE; MALE; METABOLISM; MOUSE; NEUTROPHIL; NONHUMAN; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SPLEEN CELL; SURVIVAL; TRANSGENIC MOUSE; TUNEL ASSAY; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; DIETARY SUPPLEMENT; DRUG EFFECTS; IMMUNOLOGY; LEUKEMIC INFILTRATION; LUNG; PATHOLOGY; SEPSIS; SPLEEN;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APIGENIN; APOPTOSIS; DIETARY SUPPLEMENTS; LEUKEMIC INFILTRATION; LIPOPOLYSACCHARIDES; LUNG; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NF-KAPPA B; SEPSIS; SPLEEN;

EID: 84959573253     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms17030323     Document Type: Article

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