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Volumn 35, Issue 3, 2016, Pages 333-341

Correlation between antimicrobial resistance and virulence in Klebsiella pneumoniae

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; BETA LACTAM ANTIBIOTIC; CARBAPENEMASE; CEPHALOSPORINASE; EXTENDED SPECTRUM BETA LACTAMASE; OUTER MEMBRANE PROTEIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; ANTIINFECTIVE AGENT; BETA LACTAM; BETA LACTAMASE;

EID: 84959560174     PISSN: 09349723     EISSN: 14354373     Source Type: Journal    
DOI: 10.1007/s10096-015-2559-7     Document Type: Review
Times cited : (107)

References (73)
  • 1
    • 0031792165 scopus 로고    scopus 로고
    • Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors
    • COI: 1:STN:280:DyaK1cvktVemtQ%3D%3D, PID: 9767057
    • Podschun R, Ullmann U (1998) Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors. Clin Microbiol Rev 11:589–603
    • (1998) Clin Microbiol Rev , vol.11 , pp. 589-603
    • Podschun, R.1    Ullmann, U.2
  • 2
    • 0029300353 scopus 로고
    • Comparison of pyogenic liver abscesses caused by Klebsiella pneumoniae and non-K. pneumoniae pathogens
    • COI: 1:STN:280:DyaK2Mzjslyqsw%3D%3D, PID: 7613255, Taiwan Yi Zhi
    • Chang FY, Chou MY (1995) Comparison of pyogenic liver abscesses caused by Klebsiella pneumoniae and non-K. pneumoniae pathogens. J Formos Med Assoc 94:232–237, Taiwan Yi Zhi
    • (1995) J Formos Med Assoc , vol.94 , pp. 232-237
    • Chang, F.Y.1    Chou, M.Y.2
  • 3
    • 84874209547 scopus 로고    scopus 로고
    • Hypervirulent (hypermucoviscous) Klebsiella pneumoniae: a new and dangerous breed
    • PID: 23302790
    • Shon AS, Bajwa RPS, Russo TA (2013) Hypervirulent (hypermucoviscous) Klebsiella pneumoniae: a new and dangerous breed. Virulence 4(2):107–118. doi:10.4161/viru.22718
    • (2013) Virulence , vol.4 , Issue.2 , pp. 107-118
    • Shon, A.S.1    Bajwa, R.P.S.2    Russo, T.A.3
  • 4
    • 84917677781 scopus 로고    scopus 로고
    • Molecular epidemiology and virulence factors of pyogenic liver abscess causing Klebsiella pneumoniae in China
    • COI: 1:CAS:528:DC%2BC2cXitFSnsrjI, PID: 24804560
    • Luo Y, Wang Y, Ye L, Yang J (2014) Molecular epidemiology and virulence factors of pyogenic liver abscess causing Klebsiella pneumoniae in China. Clin Microbiol Infect 20:O818–O824. doi:10.1111/1469-0691.12664
    • (2014) Clin Microbiol Infect , vol.20 , pp. O818-O824
    • Luo, Y.1    Wang, Y.2    Ye, L.3    Yang, J.4
  • 5
    • 84908087779 scopus 로고    scopus 로고
    • Genomic definition of hypervirulent and multidrug-resistant Klebsiella pneumoniae clonal groups
    • PID: 25341126
    • Bialek-Davenet S, Criscuolo A, Ailloud F, Passet V, Jones L, Delannoy-Vieillard A-S et al (2014) Genomic definition of hypervirulent and multidrug-resistant Klebsiella pneumoniae clonal groups. Emerg Infect Dis 20:1812–1820. doi:10.3201/eid2011.140206
    • (2014) Emerg Infect Dis , vol.20 , pp. 1812-1820
    • Bialek-Davenet, S.1    Criscuolo, A.2    Ailloud, F.3    Passet, V.4    Jones, L.5    Delannoy-Vieillard, A.-S.6
  • 6
    • 84864457105 scopus 로고    scopus 로고
    • Analysis of drug resistance determinants in Klebsiella pneumoniae isolates from a tertiary-care hospital in Beijing, China
    • COI: 1:CAS:528:DC%2BC38XhtFCqtr3N, PID: 22860106
    • Li B, Yi Y, Wang Q, Woo PCY, Tan L, Jing H et al (2012) Analysis of drug resistance determinants in Klebsiella pneumoniae isolates from a tertiary-care hospital in Beijing, China. PLoS One 7:e42280. doi:10.1371/journal.pone.0042280
    • (2012) PLoS One , vol.7 , pp. e42280
    • Li, B.1    Yi, Y.2    Wang, Q.3    Woo, P.C.Y.4    Tan, L.5    Jing, H.6
  • 7
    • 57749107808 scopus 로고    scopus 로고
    • Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America
    • Boucher HW, Talbot GH, Bradley JS, Edwards JE, Gilbert D, Rice LB et al (2009) Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America. Clin Infect Dis Off 48(1):1–12. doi:10.1086/595011
    • (2009) Clin Infect Dis Off , vol.48 , Issue.1 , pp. 1-12
    • Boucher, H.W.1    Talbot, G.H.2    Bradley, J.S.3    Edwards, J.E.4    Gilbert, D.5    Rice, L.B.6
  • 8
    • 84937795759 scopus 로고    scopus 로고
    • Clinical and molecular characteristics of multi-clone carbapenem-resistant hypervirulent (hypermucoviscous) Klebsiella pneumoniae isolates in a tertiary hospital in Beijing, China
    • PID: 26141415
    • Yao B, Xiao X, Wang F, Zhou L, Zhang X, Zhang J (2015) Clinical and molecular characteristics of multi-clone carbapenem-resistant hypervirulent (hypermucoviscous) Klebsiella pneumoniae isolates in a tertiary hospital in Beijing, China. Int J Infect Dis 37:107–112. doi:10.1016/j.ijid.2015.06.023
    • (2015) Int J Infect Dis , vol.37 , pp. 107-112
    • Yao, B.1    Xiao, X.2    Wang, F.3    Zhou, L.4    Zhang, X.5    Zhang, J.6
  • 9
    • 27144490073 scopus 로고    scopus 로고
    • Extended-spectrum beta-lactamases: a clinical update
    • COI: 1:CAS:528:DC%2BD2MXht1Wrsr%2FE, PID: 16223952
    • Paterson DL, Bonomo RA (2005) Extended-spectrum beta-lactamases: a clinical update. Clin Microbiol Rev 18:657–686. doi:10.1128/CMR.18.4.657-686.2005
    • (2005) Clin Microbiol Rev , vol.18 , pp. 657-686
    • Paterson, D.L.1    Bonomo, R.A.2
  • 10
    • 84882712084 scopus 로고    scopus 로고
    • Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases
    • PID: 23969216
    • Munoz-Price LS, Poirel L, Bonomo RA, Schwaber MJ, Daikos GL, Cormican M et al (2013) Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases. Lancet Infect Dis 13:785–796. doi:10.1016/S1473-3099(13)70190-7
    • (2013) Lancet Infect Dis , vol.13 , pp. 785-796
    • Munoz-Price, L.S.1    Poirel, L.2    Bonomo, R.A.3    Schwaber, M.J.4    Daikos, G.L.5    Cormican, M.6
  • 11
    • 3242771398 scopus 로고    scopus 로고
    • Sequencing and analysis of the large virulence plasmid pLVPK of Klebsiella pneumoniae CG43
    • COI: 1:CAS:528:DC%2BD2cXlvFaqtrs%3D, PID: 15276215
    • Chen Y-T, Chang H-Y, Lai Y-C, Pan C-C, Tsai S-F, Peng H-L (2004) Sequencing and analysis of the large virulence plasmid pLVPK of Klebsiella pneumoniae CG43. Gene 337:189–198. doi:10.1016/j.gene.2004.05.008
    • (2004) Gene , vol.337 , pp. 189-198
    • Chen, Y.-T.1    Chang, H.-Y.2    Lai, Y.-C.3    Pan, C.-C.4    Tsai, S.-F.5    Peng, H.-L.6
  • 12
    • 38749104320 scopus 로고    scopus 로고
    • Characterization of integrative and conjugative element ICEKp1-associated genomic heterogeneity in a Klebsiella pneumoniae strain isolated from a primary liver abscess
    • COI: 1:CAS:528:DC%2BD1cXnsVKisw%3D%3D, PID: 17981959
    • Lin T-L, Lee C-Z, Hsieh P-F, Tsai S-F, Wang J-T (2008) Characterization of integrative and conjugative element ICEKp1-associated genomic heterogeneity in a Klebsiella pneumoniae strain isolated from a primary liver abscess. J Bacteriol 190:515–526. doi:10.1128/JB.01219-07
    • (2008) J Bacteriol , vol.190 , pp. 515-526
    • Lin, T.-L.1    Lee, C.-Z.2    Hsieh, P.-F.3    Tsai, S.-F.4    Wang, J.-T.5
  • 13
    • 3042692195 scopus 로고    scopus 로고
    • Isolation of a chromosomal region of Klebsiella pneumoniae associated with allantoin metabolism and liver infection
    • COI: 1:CAS:528:DC%2BD2cXlslWjurc%3D, PID: 15213119
    • Chou H-C, Lee C-Z, Ma L-C, Fang C-T, Chang S-C, Wang J-T (2004) Isolation of a chromosomal region of Klebsiella pneumoniae associated with allantoin metabolism and liver infection. Infect Immun 72:3783–3792. doi:10.1128/IAI.72.7.3783-3792.2004
    • (2004) Infect Immun , vol.72 , pp. 3783-3792
    • Chou, H.-C.1    Lee, C.-Z.2    Ma, L.-C.3    Fang, C.-T.4    Chang, S.-C.5    Wang, J.-T.6
  • 14
    • 84936803320 scopus 로고    scopus 로고
    • Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health
    • COI: 1:CAS:528:DC%2BC2MXhtVOhsbjO, PID: 26100894
    • Holt KE, Wertheim H, Zadoks RN, Baker S, Whitehouse CA, Dance D et al (2015) Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health. Proc Natl Acad Sci U S A 112(27):E3574–E3581. doi:10.1073/pnas.1501049112
    • (2015) Proc Natl Acad Sci U S A , vol.112 , Issue.27 , pp. E3574-E3581
    • Holt, K.E.1    Wertheim, H.2    Zadoks, R.N.3    Baker, S.4    Whitehouse, C.A.5    Dance, D.6
  • 15
    • 84858178203 scopus 로고    scopus 로고
    • Association between antimicrobial resistance and virulence in Escherichia coli
    • PID: 22286707
    • Da Silva GJ, Mendonça N (2012) Association between antimicrobial resistance and virulence in Escherichia coli. Virulence 3:18–28. doi:10.4161/viru.3.1.18382
    • (2012) Virulence , vol.3 , pp. 18-28
    • Da Silva, G.J.1    Mendonça, N.2
  • 16
    • 84925296085 scopus 로고    scopus 로고
    • The genetic basis of the fitness costs of antimicrobial resistance: a meta-analysis approach
    • PID: 25861386
    • Vogwill T, MacLean RC (2015) The genetic basis of the fitness costs of antimicrobial resistance: a meta-analysis approach. Evol Appl 8:284–295. doi:10.1111/eva.12202
    • (2015) Evol Appl , vol.8 , pp. 284-295
    • Vogwill, T.1    MacLean, R.C.2
  • 17
    • 84940903440 scopus 로고    scopus 로고
    • Plasmid-mediated antibiotic resistance and virulence in gram-negatives: the Klebsiella pneumoniae paradigm
    • COI: 1:CAS:528:DC%2BC2cXitFGhurjM, PID: 25705573
    • Ramirez MS, Traglia GM, Lin DL, Tran T, Tolmasky ME (2014) Plasmid-mediated antibiotic resistance and virulence in gram-negatives: the Klebsiella pneumoniae paradigm. Microbiol Spectr 2:1–15. doi:10.1128/microbiolspec.PLAS-0016-2013
    • (2014) Microbiol Spectr , vol.2 , pp. 1-15
    • Ramirez, M.S.1    Traglia, G.M.2    Lin, D.L.3    Tran, T.4    Tolmasky, M.E.5
  • 18
    • 0023194315 scopus 로고
    • Transferable resistance to third-generation cephalosporins in clinical isolates of Klebsiella pneumoniae: identification of CTX-1, a novel beta-lactamase
    • COI: 1:CAS:528:DyaL2sXlvFCrsro%3D, PID: 3316146
    • Sirot D, Sirot J, Labia R, Morand A, Courvalin P, Darfeuille-Michaud A et al (1987) Transferable resistance to third-generation cephalosporins in clinical isolates of Klebsiella pneumoniae: identification of CTX-1, a novel beta-lactamase. J Antimicrob Chemother 20:323–334
    • (1987) J Antimicrob Chemother , vol.20 , pp. 323-334
    • Sirot, D.1    Sirot, J.2    Labia, R.3    Morand, A.4    Courvalin, P.5    Darfeuille-Michaud, A.6
  • 19
    • 84930985419 scopus 로고    scopus 로고
    • The changing epidemiology of hospital outbreaks due to ESBL-producing Klebsiella pneumoniae: the CTX-M-15 type consolidation
    • COI: 1:CAS:528:DC%2BC2MXpslGgt74%3D, PID: 26059626
    • Calbo E, Garau J (2015) The changing epidemiology of hospital outbreaks due to ESBL-producing Klebsiella pneumoniae: the CTX-M-15 type consolidation. Future Microbiol 10:1063–1075. doi:10.2217/fmb.15.22
    • (2015) Future Microbiol , vol.10 , pp. 1063-1075
    • Calbo, E.1    Garau, J.2
  • 20
    • 0028868525 scopus 로고
    • Molecular characterization and adhesive properties of CF29K, an adhesin of Klebsiella pneumoniae strains involved in nosocomial infections
    • PID: 7591068
    • Di Martino P, Bertin Y, Girardeau JP, Livrelli V, Joly B, Darfeuille-Michaud A (1995) Molecular characterization and adhesive properties of CF29K, an adhesin of Klebsiella pneumoniae strains involved in nosocomial infections. Infect Immun 63:4336–4344
    • (1995) Infect Immun , vol.63 , pp. 4336-4344
    • Di Martino, P.1    Bertin, Y.2    Girardeau, J.P.3    Livrelli, V.4    Joly, B.5    Darfeuille-Michaud, A.6
  • 21
    • 0026592686 scopus 로고
    • R-plasmid-encoded adhesive factor in Klebsiella pneumoniae strains responsible for human nosocomial infections
    • COI: 1:CAS:528:DyaK38XhsV2htLc%3D, PID: 1345909
    • Darfeuille-Michaud A, Jallat C, Aubel D, Sirot D, Rich C, Sirot J et al (1992) R-plasmid-encoded adhesive factor in Klebsiella pneumoniae strains responsible for human nosocomial infections. Infect Immun 60:44–55
    • (1992) Infect Immun , vol.60 , pp. 44-55
    • Darfeuille-Michaud, A.1    Jallat, C.2    Aubel, D.3    Sirot, D.4    Rich, C.5    Sirot, J.6
  • 22
    • 0026733739 scopus 로고
    • Incidence of two virulence factors (aerobactin and mucoid phenotype) among 190 clinical isolates of Klebsiella pneumoniae producing extended-spectrum beta-lactamase
    • COI: 1:STN:280:DyaK38vgs1SisQ%3D%3D, PID: 1388129
    • Vernet V, Madoulet C, Chippaux C, Philippon A (1992) Incidence of two virulence factors (aerobactin and mucoid phenotype) among 190 clinical isolates of Klebsiella pneumoniae producing extended-spectrum beta-lactamase. FEMS Microbiol Lett 75(1):1–5
    • (1992) FEMS Microbiol Lett , vol.75 , Issue.1 , pp. 1-5
    • Vernet, V.1    Madoulet, C.2    Chippaux, C.3    Philippon, A.4
  • 23
    • 63449117143 scopus 로고    scopus 로고
    • Virulent clones of Klebsiella pneumoniae: identification and evolutionary scenario based on genomic and phenotypic characterization
    • PID: 19319196
    • Brisse S, Fevre C, Passet V, Issenhuth-Jeanjean S, Tournebize R, Diancourt L et al (2009) Virulent clones of Klebsiella pneumoniae: identification and evolutionary scenario based on genomic and phenotypic characterization. PLoS One 4:e4982. doi:10.1371/journal.pone.0004982
    • (2009) PLoS One , vol.4 , pp. e4982
    • Brisse, S.1    Fevre, C.2    Passet, V.3    Issenhuth-Jeanjean, S.4    Tournebize, R.5    Diancourt, L.6
  • 24
    • 84896960846 scopus 로고    scopus 로고
    • Comparative study of genotype and virulence in CTX-M-producing and non-extended-spectrum-β-lactamase-producing Klebsiella pneumoniae isolates
    • PID: 24514097
    • Shin J, Ko KS (2014) Comparative study of genotype and virulence in CTX-M-producing and non-extended-spectrum-β-lactamase-producing Klebsiella pneumoniae isolates. Antimicrob Agents Chemother 58:2463–2467. doi:10.1128/AAC.02499-13
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 2463-2467
    • Shin, J.1    Ko, K.S.2
  • 26
    • 0029991626 scopus 로고    scopus 로고
    • A new fimbrial antigen harbored by CAZ-5/SHV-4-producing Klebsiella pneumoniae strains involved in nosocomial infections
    • PID: 8675336
    • Di Martino P, Livrelli V, Sirot D, Joly B, Darfeuille-Michaud A (1996) A new fimbrial antigen harbored by CAZ-5/SHV-4-producing Klebsiella pneumoniae strains involved in nosocomial infections. Infect Immun 64:2266–2273
    • (1996) Infect Immun , vol.64 , pp. 2266-2273
    • Di Martino, P.1    Livrelli, V.2    Sirot, D.3    Joly, B.4    Darfeuille-Michaud, A.5
  • 27
    • 50949108629 scopus 로고    scopus 로고
    • Extended-spectrum beta-lactamase production is associated with an increase in cell invasion and expression of fimbrial adhesins in Klebsiella pneumoniae
    • COI: 1:CAS:528:DC%2BD1cXhtF2gtrjK, PID: 18573929
    • Sahly H, Navon-Venezia S, Roesler L, Hay A, Carmeli Y, Podschun R et al (2008) Extended-spectrum beta-lactamase production is associated with an increase in cell invasion and expression of fimbrial adhesins in Klebsiella pneumoniae. Antimicrob Agents Chemother 52:3029–3034. doi:10.1128/AAC.00010-08
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 3029-3034
    • Sahly, H.1    Navon-Venezia, S.2    Roesler, L.3    Hay, A.4    Carmeli, Y.5    Podschun, R.6
  • 28
    • 0029895048 scopus 로고    scopus 로고
    • Adhesive properties and antibiotic resistance of Klebsiella, Enterobacter, and Serratia clinical isolates involved in nosocomial infections
    • COI: 1:STN:280:DyaK28vhsF2rtg%3D%3D, PID: 8818891
    • Livrelli V, De Champs C, Di Martino P, Darfeuille-Michaud A, Forestier C, Joly B (1996) Adhesive properties and antibiotic resistance of Klebsiella, Enterobacter, and Serratia clinical isolates involved in nosocomial infections. J Clin Microbiol 34:1963–1969
    • (1996) J Clin Microbiol , vol.34 , pp. 1963-1969
    • Livrelli, V.1    De Champs, C.2    Di Martino, P.3    Darfeuille-Michaud, A.4    Forestier, C.5    Joly, B.6
  • 29
    • 4344700727 scopus 로고    scopus 로고
    • Increased serum resistance in Klebsiella pneumoniae strains producing extended-spectrum β-lactamases
    • COI: 1:CAS:528:DC%2BD2cXnsVehsL4%3D, PID: 15328114
    • Sahly H, Aucken H, Benedí VJ, Forestier C, Fussing V, Hansen DS et al (2004) Increased serum resistance in Klebsiella pneumoniae strains producing extended-spectrum β-lactamases. Antimicrob Agents Chemother 48(9):3477–3482. doi:10.1128/AAC.48.9.3477-3482.2004
    • (2004) Antimicrob Agents Chemother , vol.48 , Issue.9 , pp. 3477-3482
    • Sahly, H.1    Aucken, H.2    Benedí, V.J.3    Forestier, C.4    Fussing, V.5    Hansen, D.S.6
  • 30
    • 84856074262 scopus 로고    scopus 로고
    • Virulence factors and TEM-type β-lactamases produced by two isolates of an epidemic Klebsiella pneumoniae strain
    • COI: 1:CAS:528:DC%2BC38Xhs1Gqsr0%3D, PID: 22106220
    • Robin F, Hennequin C, Gniadkowski M, Beyrouthy R, Empel J, Gibold L et al (2012) Virulence factors and TEM-type β-lactamases produced by two isolates of an epidemic Klebsiella pneumoniae strain. Antimicrob Agents Chemother 56:1101–1104. doi:10.1128/AAC.05079-11
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 1101-1104
    • Robin, F.1    Hennequin, C.2    Gniadkowski, M.3    Beyrouthy, R.4    Empel, J.5    Gibold, L.6
  • 31
    • 84886778445 scopus 로고    scopus 로고
    • Virulence profiles and antibiotic susceptibility patterns of Klebsiella pneumoniae strains isolated from different clinical specimens
    • El Fertas-Aissani R, Messai Y, Alouache S, Bakour R (2013) Virulence profiles and antibiotic susceptibility patterns of Klebsiella pneumoniae strains isolated from different clinical specimens. Pathol Biol (Paris) 61:209–216. doi:10.1016/j.patbio.2012.10.004
    • (2013) Pathol Biol (Paris) , vol.61 , pp. 209-216
    • El Fertas-Aissani, R.1    Messai, Y.2    Alouache, S.3    Bakour, R.4
  • 32
    • 34249290701 scopus 로고    scopus 로고
    • Influence of capsule and extended-spectrum beta-lactamases encoding plasmids upon Klebsiella pneumoniae adhesion
    • COI: 1:CAS:528:DC%2BD2sXmtVGgtrg%3D, PID: 17446046
    • Hennequin C, Forestier C (2007) Influence of capsule and extended-spectrum beta-lactamases encoding plasmids upon Klebsiella pneumoniae adhesion. Res Microbiol 158:339–347. doi:10.1016/j.resmic.2007.02.005
    • (2007) Res Microbiol , vol.158 , pp. 339-347
    • Hennequin, C.1    Forestier, C.2
  • 33
    • 84865353098 scopus 로고    scopus 로고
    • Antibiotic resistance and plasmid transfer capacity in biofilm formed with a CTX-M-15-producing Klebsiella pneumoniae isolate
    • COI: 1:CAS:528:DC%2BC38Xht1egt7zM, PID: 22577106
    • Hennequin C, Aumeran C, Robin F, Traore O, Forestier C (2012) Antibiotic resistance and plasmid transfer capacity in biofilm formed with a CTX-M-15-producing Klebsiella pneumoniae isolate. J Antimicrob Chemother 67:2123–2130. doi:10.1093/jac/dks169
    • (2012) J Antimicrob Chemother , vol.67 , pp. 2123-2130
    • Hennequin, C.1    Aumeran, C.2    Robin, F.3    Traore, O.4    Forestier, C.5
  • 34
    • 84931275547 scopus 로고    scopus 로고
    • Characterization of pre-antibiotic era Klebsiella pneumoniae isolates with respect to antibiotic/disinfectant susceptibility and virulence in Galleria mellonella
    • COI: 1:CAS:528:DC%2BC2MXhtFaru7jE, PID: 25896708
    • Wand ME, Baker KS, Benthall G, McGregor H, McCowen JWI, Deheer-Graham A et al (2015) Characterization of pre-antibiotic era Klebsiella pneumoniae isolates with respect to antibiotic/disinfectant susceptibility and virulence in Galleria mellonella. Antimicrob Agents Chemother 59:3966–3972. doi:10.1128/AAC.05009-14
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 3966-3972
    • Wand, M.E.1    Baker, K.S.2    Benthall, G.3    McGregor, H.4    McCowen, J.W.I.5    Deheer-Graham, A.6
  • 35
    • 84859170554 scopus 로고    scopus 로고
    • Transfer of an Escherichia coli ST131 multiresistance cassette has created a Klebsiella pneumoniae-specific plasmid associated with a major nosocomial outbreak
    • COI: 1:CAS:528:DC%2BC3MXhs1CqtLjJ, PID: 21990049
    • Sandegren L, Linkevicius M, Lytsy B, Melhus Å, Andersson DI (2012) Transfer of an Escherichia coli ST131 multiresistance cassette has created a Klebsiella pneumoniae-specific plasmid associated with a major nosocomial outbreak. J Antimicrob Chemother 67:74–83. doi:10.1093/jac/dkr405
    • (2012) J Antimicrob Chemother , vol.67 , pp. 74-83
    • Sandegren, L.1    Linkevicius, M.2    Lytsy, B.3    Melhus, Å.4    Andersson, D.I.5
  • 36
    • 84896484651 scopus 로고    scopus 로고
    • Single origin of three plasmids bearing blaCTX-M-15 from different Klebsiella pneumoniae clones
    • COI: 1:CAS:528:DC%2BC2cXktlOisbY%3D, PID: 24257316
    • Shin J, Soo KK (2014) Single origin of three plasmids bearing blaCTX-M-15 from different Klebsiella pneumoniae clones. J Antimicrob Chemother 69:969–972. doi:10.1093/jac/dkt464
    • (2014) J Antimicrob Chemother , vol.69 , pp. 969-972
    • Shin, J.1    Soo, K.K.2
  • 37
    • 84926664369 scopus 로고    scopus 로고
    • Low prevalence of rmpA and high tendency of rmpA mutation correspond to low virulence of extended spectrum β-lactamase-producing Klebsiella pneumoniae isolates
    • COI: 1:CAS:528:DC%2BC28XhtlKktLc%3D, PID: 25830726
    • Yu W-L, Lee M-F, Tang H-J, Chang M-C, Chuang Y-C (2015) Low prevalence of rmpA and high tendency of rmpA mutation correspond to low virulence of extended spectrum β-lactamase-producing Klebsiella pneumoniae isolates. Virulence 6:162–172. doi:10.1080/21505594.2015.1016703
    • (2015) Virulence , vol.6 , pp. 162-172
    • Yu, W.-L.1    Lee, M.-F.2    Tang, H.-J.3    Chang, M.-C.4    Chuang, Y.-C.5
  • 38
    • 0036136152 scopus 로고    scopus 로고
    • Plasmid-determined AmpC-type beta-lactamases
    • COI: 1:CAS:528:DC%2BD38XjtVartg%3D%3D, PID: 11751104
    • Philippon A, Arlet G, Jacoby GA (2002) Plasmid-determined AmpC-type beta-lactamases. Antimicrob Agents Chemother 46:1–11
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 1-11
    • Philippon, A.1    Arlet, G.2    Jacoby, G.A.3
  • 39
    • 0031710603 scopus 로고    scopus 로고
    • Salmonella enteritidis: AmpC plasmid-mediated inducible beta-lactamase (DHA-1) with an ampR gene from Morganella morganii
    • COI: 1:CAS:528:DyaK1cXmtVWqsbk%3D, PID: 9736562
    • Barnaud G, Arlet G, Verdet C, Gaillot O, Lagrange PH, Philippon A (1998) Salmonella enteritidis: AmpC plasmid-mediated inducible beta-lactamase (DHA-1) with an ampR gene from Morganella morganii. Antimicrob Agents Chemother 42:2352–2358
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 2352-2358
    • Barnaud, G.1    Arlet, G.2    Verdet, C.3    Gaillot, O.4    Lagrange, P.H.5    Philippon, A.6
  • 40
    • 84929507229 scopus 로고    scopus 로고
    • Molecular characterization of DHA-1-producing Klebsiella pneumoniae isolates collected during a 4-year period in an intensive care unit
    • COI: 1:CAS:528:DC%2BC2cXhtF2ksLbL, PID: 25053201
    • Compain F, Decré D, Fulgencio J-P, Berraho S, Arlet G, Verdet C (2014) Molecular characterization of DHA-1-producing Klebsiella pneumoniae isolates collected during a 4-year period in an intensive care unit. Diagn Microbiol Infect Dis 80:159–161. doi:10.1016/j.diagmicrobio.2014.06.009
    • (2014) Diagn Microbiol Infect Dis , vol.80 , pp. 159-161
    • Compain, F.1    Decré, D.2    Fulgencio, J.-P.3    Berraho, S.4    Arlet, G.5    Verdet, C.6
  • 41
    • 84455192731 scopus 로고    scopus 로고
    • Characterization of a DHA-1-producing Klebsiella pneumoniae strain involved in an outbreak and role of the AmpR regulator in virulence
    • COI: 1:CAS:528:DC%2BC38Xjt1Gqsw%3D%3D, PID: 21986829
    • Hennequin C, Robin F, Cabrolier N, Bonnet R, Forestier C (2012) Characterization of a DHA-1-producing Klebsiella pneumoniae strain involved in an outbreak and role of the AmpR regulator in virulence. Antimicrob Agents Chemother 56:288–294. doi:10.1128/AAC.00164-11
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 288-294
    • Hennequin, C.1    Robin, F.2    Cabrolier, N.3    Bonnet, R.4    Forestier, C.5
  • 42
    • 0035084032 scopus 로고    scopus 로고
    • Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae
    • COI: 1:CAS:528:DC%2BD3MXit1Omsrc%3D, PID: 11257029
    • Yigit H, Queenan AM, Anderson GJ, Domenech-Sanchez A, Biddle JW, Steward CD et al (2001) Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae. Antimicrob Agents Chemother 45:1151–1161. doi:10.1128/AAC.45.4.1151-1161.2001
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 1151-1161
    • Yigit, H.1    Queenan, A.M.2    Anderson, G.J.3    Domenech-Sanchez, A.4    Biddle, J.W.5    Steward, C.D.6
  • 43
    • 84879762016 scopus 로고    scopus 로고
    • Virulence of Klebsiella pneumoniae isolates harboring bla KPC-2 carbapenemase gene in a Caenorhabditis elegans model
    • COI: 1:CAS:528:DC%2BC3sXhtFGru7vK, PID: 23844109
    • Lavigne J-P, Cuzon G, Combescure C, Bourg G, Sotto A, Nordmann P (2013) Virulence of Klebsiella pneumoniae isolates harboring bla KPC-2 carbapenemase gene in a Caenorhabditis elegans model. PLoS One 8:e67847. doi:10.1371/journal.pone.0067847
    • (2013) PLoS One , vol.8 , pp. e67847
    • Lavigne, J.-P.1    Cuzon, G.2    Combescure, C.3    Bourg, G.4    Sotto, A.5    Nordmann, P.6
  • 45
    • 0347951399 scopus 로고    scopus 로고
    • Emergence of oxacillinase-mediated resistance to imipenem in Klebsiella pneumoniae
    • COI: 1:CAS:528:DC%2BD2cXlsVKlug%3D%3D, PID: 14693513
    • Poirel L, Héritier C, Tolün V, Nordmann P (2004) Emergence of oxacillinase-mediated resistance to imipenem in Klebsiella pneumoniae. Antimicrob Agents Chemother 48:15–22
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 15-22
    • Poirel, L.1    Héritier, C.2    Tolün, V.3    Nordmann, P.4
  • 46
    • 84871247747 scopus 로고    scopus 로고
    • Outbreak of OXA-48 carbapenemase-producing Klebsiella pneumoniae in Greece involving an ST11 clone
    • COI: 1:CAS:528:DC%2BC38XhvVChsbnJ, PID: 22945916
    • Voulgari E, Zarkotou O, Ranellou K, Karageorgopoulos DE, Vrioni G, Mamali V et al (2013) Outbreak of OXA-48 carbapenemase-producing Klebsiella pneumoniae in Greece involving an ST11 clone. J Antimicrob Chemother 68:84–88. doi:10.1093/jac/dks356
    • (2013) J Antimicrob Chemother , vol.68 , pp. 84-88
    • Voulgari, E.1    Zarkotou, O.2    Ranellou, K.3    Karageorgopoulos, D.E.4    Vrioni, G.5    Mamali, V.6
  • 47
    • 84864337411 scopus 로고    scopus 로고
    • Virulence and plasmid transferability of KPC Klebsiella pneumoniae at the Veterans Affairs Healthcare System of New Jersey
    • COI: 1:CAS:528:DC%2BC38XhtFansL%2FL, PID: 22533374
    • Siu LK, Lin J-C, Gomez E, Eng R, Chiang T (2012) Virulence and plasmid transferability of KPC Klebsiella pneumoniae at the Veterans Affairs Healthcare System of New Jersey. Microb Drug Resist 18:380–384. doi:10.1089/mdr.2011.0241
    • (2012) Microb Drug Resist , vol.18 , pp. 380-384
    • Siu, L.K.1    Lin, J.-C.2    Gomez, E.3    Eng, R.4    Chiang, T.5
  • 48
    • 84923186531 scopus 로고    scopus 로고
    • Critical issues for Klebsiella pneumoniae KPC-carbapenemase producing K. pneumoniae infections: a critical agenda
    • PID: 25689539
    • De Rosa FG, Corcione S, Cavallo R, Di Perri G, Bassetti M (2015) Critical issues for Klebsiella pneumoniae KPC-carbapenemase producing K. pneumoniae infections: a critical agenda. Future Microbiol 10:283–294. doi:10.2217/fmb.14.121
    • (2015) Future Microbiol , vol.10 , pp. 283-294
    • De Rosa, F.G.1    Corcione, S.2    Cavallo, R.3    Di Perri, G.4    Bassetti, M.5
  • 49
    • 84892643683 scopus 로고    scopus 로고
    • Quantifying the clinical virulence of Klebsiella pneumoniae producing carbapenemase Klebsiella pneumoniae with a Galleria mellonella model and a pilot study to translate to patient outcomes
    • PID: 24428847
    • McLaughlin MM, Advincula MR, Malczynski M, Barajas G, Qi C, Scheetz MH (2014) Quantifying the clinical virulence of Klebsiella pneumoniae producing carbapenemase Klebsiella pneumoniae with a Galleria mellonella model and a pilot study to translate to patient outcomes. BMC Infect Dis 14:31. doi:10.1186/1471-2334-14-31
    • (2014) BMC Infect Dis , vol.14 , pp. 31
    • McLaughlin, M.M.1    Advincula, M.R.2    Malczynski, M.3    Barajas, G.4    Qi, C.5    Scheetz, M.H.6
  • 50
    • 84920745359 scopus 로고    scopus 로고
    • Carbapenemase and virulence factors of Enterobacteriaceae in North Lebanon between 2008 and 2012: evolution via endemic spread of OXA-48
    • COI: 1:CAS:528:DC%2BC2MXis1Ciu7g%3D, PID: 24903637
    • Beyrouthy R, Robin F, Dabboussi F, Mallat H, Hamzé M, Bonnet R (2014) Carbapenemase and virulence factors of Enterobacteriaceae in North Lebanon between 2008 and 2012: evolution via endemic spread of OXA-48. J Antimicrob Chemother 69:2699–2705. doi:10.1093/jac/dku181
    • (2014) J Antimicrob Chemother , vol.69 , pp. 2699-2705
    • Beyrouthy, R.1    Robin, F.2    Dabboussi, F.3    Mallat, H.4    Hamzé, M.5    Bonnet, R.6
  • 51
    • 84856002526 scopus 로고    scopus 로고
    • Virulence of a Klebsiella pneumoniae strain carrying the New Delhi metallo-beta-lactamase-1 (NDM-1)
    • COI: 1:CAS:528:DC%2BC38Xht1Oms70%3D, PID: 21925284
    • Fuursted K, Schøler L, Hansen F, Dam K, Bojer MS, Hammerum AM et al (2012) Virulence of a Klebsiella pneumoniae strain carrying the New Delhi metallo-beta-lactamase-1 (NDM-1). Microbes Infect 14:155–158. doi:10.1016/j.micinf.2011.08.015
    • (2012) Microbes Infect , vol.14 , pp. 155-158
    • Fuursted, K.1    Schøler, L.2    Hansen, F.3    Dam, K.4    Bojer, M.S.5    Hammerum, A.M.6
  • 52
    • 77953717790 scopus 로고    scopus 로고
    • Contribution of outer membrane protein K36 to antimicrobial resistance and virulence in Klebsiella pneumoniae
    • COI: 1:CAS:528:DC%2BC3cXks1Gnurw%3D, PID: 20211860
    • Chen J-H, Siu LK, Fung C-P, Lin J-C, Yeh K-M, Chen T-L et al (2010) Contribution of outer membrane protein K36 to antimicrobial resistance and virulence in Klebsiella pneumoniae. J Antimicrob Chemother 65:986–990. doi:10.1093/jac/dkq056
    • (2010) J Antimicrob Chemother , vol.65 , pp. 986-990
    • Chen, J.-H.1    Siu, L.K.2    Fung, C.-P.3    Lin, J.-C.4    Yeh, K.-M.5    Chen, T.-L.6
  • 53
    • 32944469152 scopus 로고    scopus 로고
    • Identification of vaccine candidate antigens of an ESBL producing Klebsiella pneumoniae clinical strain by immunoproteome analysis
    • COI: 1:CAS:528:DC%2BD28XhvFWkurk%3D, PID: 16372264
    • Kurupati P, Teh BK, Kumarasinghe G, Poh CL (2006) Identification of vaccine candidate antigens of an ESBL producing Klebsiella pneumoniae clinical strain by immunoproteome analysis. Proteomics 6:836–844. doi:10.1002/pmic.200500214
    • (2006) Proteomics , vol.6 , pp. 836-844
    • Kurupati, P.1    Teh, B.K.2    Kumarasinghe, G.3    Poh, C.L.4
  • 54
    • 79953222226 scopus 로고    scopus 로고
    • Klebsiella pneumoniae outer membrane porins OmpK35 and OmpK36 play roles in both antimicrobial resistance and virulence
    • COI: 1:CAS:528:DC%2BC38XhsFynu74%3D, PID: 21282452
    • Tsai Y-K, Fung C-P, Lin J-C, Chen J-H, Chang F-Y, Chen T-L et al (2011) Klebsiella pneumoniae outer membrane porins OmpK35 and OmpK36 play roles in both antimicrobial resistance and virulence. Antimicrob Agents Chemother 55:1485–1493. doi:10.1128/AAC.01275-10
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 1485-1493
    • Tsai, Y.-K.1    Fung, C.-P.2    Lin, J.-C.3    Chen, J.-H.4    Chang, F.-Y.5    Chen, T.-L.6
  • 55
    • 77957371841 scopus 로고    scopus 로고
    • Membrane efflux and influx modulate both multidrug resistance and virulence of Klebsiella pneumoniae in a Caenorhabditis elegans model
    • COI: 1:CAS:528:DC%2BC3cXhtlegtr3N, PID: 20679507
    • Bialek S, Lavigne J-P, Chevalier J, Marcon E, Leflon-Guibout V, Davin A et al (2010) Membrane efflux and influx modulate both multidrug resistance and virulence of Klebsiella pneumoniae in a Caenorhabditis elegans model. Antimicrob Agents Chemother 54:4373–4378. doi:10.1128/AAC.01607-09
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 4373-4378
    • Bialek, S.1    Lavigne, J.-P.2    Chevalier, J.3    Marcon, E.4    Leflon-Guibout, V.5    Davin, A.6
  • 56
    • 84874066976 scopus 로고    scopus 로고
    • Role of bacterial surface structures on the interaction of Klebsiella pneumoniae with phagocytes
    • COI: 1:CAS:528:DC%2BC3sXjsVartLk%3D, PID: 23457627
    • March C, Cano V, Moranta D, Llobet E, Pérez-Gutiérrez C, Tomás JM et al (2013) Role of bacterial surface structures on the interaction of Klebsiella pneumoniae with phagocytes. PLoS One 8:e56847. doi:10.1371/journal.pone.0056847
    • (2013) PLoS One , vol.8 , pp. e56847
    • March, C.1    Cano, V.2    Moranta, D.3    Llobet, E.4    Pérez-Gutiérrez, C.5    Tomás, J.M.6
  • 57
    • 3142552587 scopus 로고    scopus 로고
    • Factors associated with antimicrobial resistance among clinical isolates of Klebsiella pneumoniae: 1-year survey in a French university hospital
    • PID: 15148654
    • De Champs C, Rich C, Chandezon P, Chanal C, Sirot D, Forestier C (2004) Factors associated with antimicrobial resistance among clinical isolates of Klebsiella pneumoniae: 1-year survey in a French university hospital. Eur J Clin Microbiol Infect Dis 23:456–462. doi:10.1007/s10096-004-1144-2
    • (2004) Eur J Clin Microbiol Infect Dis , vol.23 , pp. 456-462
    • De Champs, C.1    Rich, C.2    Chandezon, P.3    Chanal, C.4    Sirot, D.5    Forestier, C.6
  • 58
    • 33747154459 scopus 로고    scopus 로고
    • Multidrug-resistance efflux pumps—not just for resistance
    • COI: 1:CAS:528:DC%2BD28XmvFamuro%3D, PID: 16845433
    • Piddock LJV (2006) Multidrug-resistance efflux pumps—not just for resistance. Nat Rev Microbiol 4:629–636. doi:10.1038/nrmicro1464
    • (2006) Nat Rev Microbiol , vol.4 , pp. 629-636
    • Piddock, L.J.V.1
  • 60
    • 84864388734 scopus 로고    scopus 로고
    • Characterization of RarA, a novel AraC family multidrug resistance regulator in Klebsiella pneumoniae
    • COI: 1:CAS:528:DC%2BC38XhtFajsL7O, PID: 22644028
    • Veleba M, Higgins PG, Gonzalez G, Seifert H, Schneiders T (2012) Characterization of RarA, a novel AraC family multidrug resistance regulator in Klebsiella pneumoniae. Antimicrob Agents Chemother 56:4450–4458. doi:10.1128/AAC.00456-12
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 4450-4458
    • Veleba, M.1    Higgins, P.G.2    Gonzalez, G.3    Seifert, H.4    Schneiders, T.5
  • 61
    • 84964301249 scopus 로고    scopus 로고
    • Differential contribution of AcrAB and OqxAB efflux pumps to multidrug resistance and virulence in Klebsiella pneumoniae
    • COI: 1:CAS:528:DC%2BC2MXisFarsrg%3D, PID: 25193085
    • Bialek-Davenet S, Lavigne J-P, Guyot K, Mayer N, Tournebize R, Brisse S et al (2015) Differential contribution of AcrAB and OqxAB efflux pumps to multidrug resistance and virulence in Klebsiella pneumoniae. J Antimicrob Chemother 70:81–88. doi:10.1093/jac/dku340
    • (2015) J Antimicrob Chemother , vol.70 , pp. 81-88
    • Bialek-Davenet, S.1    Lavigne, J.-P.2    Guyot, K.3    Mayer, N.4    Tournebize, R.5    Brisse, S.6
  • 62
    • 84858749054 scopus 로고    scopus 로고
    • Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae
    • COI: 1:CAS:528:DC%2BC38Xjs1Kjtrc%3D, PID: 22391093
    • Ogawa W, Onishi M, Ni R, Tsuchiya T, Kuroda T (2012) Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae. Gene 498(2):177–182. doi:10.1016/j.gene.2012.02.008
    • (2012) Gene , vol.498 , Issue.2 , pp. 177-182
    • Ogawa, W.1    Onishi, M.2    Ni, R.3    Tsuchiya, T.4    Kuroda, T.5
  • 63
    • 53649091868 scopus 로고    scopus 로고
    • A tripartite efflux pump involved in gastrointestinal colonization by Klebsiella pneumoniae confers a tolerance response to inorganic acid
    • COI: 1:CAS:528:DC%2BD1cXhtF2jtbjL, PID: 18644883
    • Coudeyras S, Nakusi L, Charbonnel N, Forestier C (2008) A tripartite efflux pump involved in gastrointestinal colonization by Klebsiella pneumoniae confers a tolerance response to inorganic acid. Infect Immun 76:4633–4641. doi:10.1128/IAI.00356-08
    • (2008) Infect Immun , vol.76 , pp. 4633-4641
    • Coudeyras, S.1    Nakusi, L.2    Charbonnel, N.3    Forestier, C.4
  • 64
    • 84926388808 scopus 로고    scopus 로고
    • Characterization of MATE-type multidrug efflux pumps from Klebsiella pneumoniae MGH78578
    • PID: 25807080
    • Ogawa W, Minato Y, Dodan H, Onishi M, Tsuchiya T, Kuroda T (2015) Characterization of MATE-type multidrug efflux pumps from Klebsiella pneumoniae MGH78578. PLoS One 10:e0121619. doi:10.1371/journal.pone.0121619
    • (2015) PLoS One , vol.10 , pp. e0121619
    • Ogawa, W.1    Minato, Y.2    Dodan, H.3    Onishi, M.4    Tsuchiya, T.5    Kuroda, T.6
  • 65
    • 0036895630 scopus 로고    scopus 로고
    • AcrAB efflux system: expression and contribution to fluoroquinolone resistance in Klebsiella spp
    • COI: 1:CAS:528:DC%2BD38XptVynurw%3D, PID: 12435706
    • Mazzariol A, Zuliani J, Cornaglia G, Rossolini GM, Fontana R (2002) AcrAB efflux system: expression and contribution to fluoroquinolone resistance in Klebsiella spp. Antimicrob Agents Chemother 46:3984–3986
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 3984-3986
    • Mazzariol, A.1    Zuliani, J.2    Cornaglia, G.3    Rossolini, G.M.4    Fontana, R.5
  • 66
    • 84887507986 scopus 로고    scopus 로고
    • Risk factors and clinical characteristics of patients with qnr-positive Klebsiella pneumoniae bacteraemia
    • COI: 1:CAS:528:DC%2BC3sXhslCrsLfI, PID: 23956373
    • Liao C-H, Hsueh P-R, Jacoby GA, Hooper DC (2013) Risk factors and clinical characteristics of patients with qnr-positive Klebsiella pneumoniae bacteraemia. J Antimicrob Chemother 68:2907–2914. doi:10.1093/jac/dkt295
    • (2013) J Antimicrob Chemother , vol.68 , pp. 2907-2914
    • Liao, C.-H.1    Hsueh, P.-R.2    Jacoby, G.A.3    Hooper, D.C.4
  • 67
    • 84900829932 scopus 로고    scopus 로고
    • Fitness cost associated with resistance to fluoroquinolones is diverse across clones of Klebsiella pneumoniae and may select for CTX-M-15 type extended-spectrum β-lactamase
    • PID: 24306097
    • Tóth A, Kocsis B, Damjanova I, Kristóf K, Jánvári L, Pászti J et al (2014) Fitness cost associated with resistance to fluoroquinolones is diverse across clones of Klebsiella pneumoniae and may select for CTX-M-15 type extended-spectrum β-lactamase. Eur J Clin Microbiol Infect Dis 33:837–843. doi:10.1007/s10096-013-2022-6
    • (2014) Eur J Clin Microbiol Infect Dis , vol.33 , pp. 837-843
    • Tóth, A.1    Kocsis, B.2    Damjanova, I.3    Kristóf, K.4    Jánvári, L.5    Pászti, J.6
  • 68
    • 84902551410 scopus 로고    scopus 로고
    • Colistin resistance in Klebsiella pneumoniae
    • COI: 1:CAS:528:DC%2BC2cXntl2mt74%3D, PID: 24794735
    • Ah Y-M, Kim A-J, Lee J-Y (2014) Colistin resistance in Klebsiella pneumoniae. Int J Antimicrob Agents 44:8–15. doi:10.1016/j.ijantimicag.2014.02.016
    • (2014) Int J Antimicrob Agents , vol.44 , pp. 8-15
    • Ah, Y.-M.1    Kim, A.-J.2    Lee, J.-Y.3
  • 69
    • 84885909781 scopus 로고    scopus 로고
    • In vivo emergence of colistin resistance in Klebsiella pneumoniae producing KPC-type carbapenemases mediated by insertional inactivation of the PhoQ/PhoP mgrB regulator
    • COI: 1:CAS:528:DC%2BC3sXhs1Kjtr7J, PID: 23979739
    • Cannatelli A, D’Andrea MM, Giani T, Di Pilato V, Arena F, Ambretti S et al (2013) In vivo emergence of colistin resistance in Klebsiella pneumoniae producing KPC-type carbapenemases mediated by insertional inactivation of the PhoQ/PhoP mgrB regulator. Antimicrob Agents Chemother 57:5521–5526. doi:10.1128/AAC.01480-13
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 5521-5526
    • Cannatelli, A.1    D’Andrea, M.M.2    Giani, T.3    Di Pilato, V.4    Arena, F.5    Ambretti, S.6
  • 70
    • 84920148701 scopus 로고    scopus 로고
    • Genomic and transcriptomic analyses of colistin-resistant clinical isolates of Klebsiella pneumoniae reveal multiple pathways of resistance
    • PID: 25385117
    • Wright MS, Suzuki Y, Jones MB, Marshall SH, Rudin SD, van Duin D et al (2015) Genomic and transcriptomic analyses of colistin-resistant clinical isolates of Klebsiella pneumoniae reveal multiple pathways of resistance. Antimicrob Agents Chemother 59:536–543. doi:10.1128/AAC.04037-14
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 536-543
    • Wright, M.S.1    Suzuki, Y.2    Jones, M.B.3    Marshall, S.H.4    Rudin, S.D.5    van Duin, D.6
  • 71
    • 84946200308 scopus 로고    scopus 로고
    • Loss of hypermucoviscosity and increased fitness cost in colistin-resistant Klebsiella pneumoniae sequence type 23 strains
    • Choi M-J, Ko KS (2015) Loss of hypermucoviscosity and increased fitness cost in colistin-resistant Klebsiella pneumoniae sequence type 23 strains. Antimicrob Agents Chemother 59:6763–6773. doi:10.1128/AAC.00952-15
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 6763-6773
    • Choi, M.-J.1    Ko, K.S.2
  • 73
    • 84892653407 scopus 로고    scopus 로고
    • Comparative analysis of the complete genome of KPC-2-producing Klebsiella pneumoniae Kp13 reveals remarkable genome plasticity and a wide repertoire of virulence and resistance mechanisms
    • PID: 24450656
    • Ramos PIP, Picão RC, de Almeida LGP, Lima NCB, Girardello R, Vivan ACP et al (2014) Comparative analysis of the complete genome of KPC-2-producing Klebsiella pneumoniae Kp13 reveals remarkable genome plasticity and a wide repertoire of virulence and resistance mechanisms. BMC Genomics 15:54. doi:10.1186/1471-2164-15-54
    • (2014) BMC Genomics , vol.15 , pp. 54
    • Ramos, P.I.P.1    Picão, R.C.2    de Almeida, L.G.P.3    Lima, N.C.B.4    Girardello, R.5    Vivan, A.C.P.6


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