Molecular characterization of DHA-1-producing Klebsiella pneumoniae isolates collected during a 4-year period in an intensive care unit

Diagnostic Microbiology and Infectious Disease

Volumn 80, Issue 2, 2014, Pages 159-161

  Compain, Fabrice ^a   Decré, Dominique ^a,b   Fulgencio, Jean Pierre ^c   Berraho, Sfia ^a   Arlet, Guillaume ^a,b,c   Verdet, Charlotte ^c  

^a SORBONNE UNIVERSITÉ   (France)

^b HÔPITAL SAINT ANTOINE   (France)

^c HÔPITAL TENON   (France)

Author keywords

DHA 1; Klebsiella pneumoniae; Plasmid typing

Indexed keywords

BETA LACTAMASE; CEPHALOSPORINASE; DHA-1 CEPHALOSPORINASE, E COLI; ESCHERICHIA COLI PROTEIN;

ARTICLE; BACTERIAL GENOME; BACTERIAL STRAIN; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; BLADHA 1 GENE; BLASHV 12 GENE; ELECTROPORATION; ESCHERICHIA COLI; GENE; INTENSIVE CARE UNIT; KLEBSIELLA OXYTOCA; KLEBSIELLA PNEUMONIAE; LENGTH OF STAY; MULTILOCUS SEQUENCE TYPING; NONHUMAN; PREVALENCE; PRIORITY JOURNAL; QNRB4 GENE; ANALYSIS; CLASSIFICATION; ENZYMOLOGY; GENETICS; GENOTYPE; HUMAN; ISOLATION AND PURIFICATION; KLEBSIELLA INFECTION; MICROBIOLOGY; MOLECULAR TYPING; PLASMID; SECRETION (PROCESS);

CEPHALOSPORINASE; ESCHERICHIA COLI PROTEINS; GENOTYPE; HUMANS; INTENSIVE CARE UNITS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MOLECULAR TYPING; PLASMIDS;

EID: 84929507229     PISSN: 07328893     EISSN: 18790070     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2014.06.009     Document Type: Article

References (26)

1. Carattoli A. Resistance plasmid families in Enterobacteriaceae. Antimicrob Agents Chemother 2009, 53(6):2227-2238.
2. Carattoli A., Bertini A., Villa L., Falbo V., Hopkins K.L., Threlfall E.J. Identification of plasmids by PCR-based replicon typing. J Microbiol Methods 2005, 63(3):219-228.
3. Cattoir V., Poirel L., Rotimi V., Soussy C.-J., Nordmann P. Multiplex PCR for detection of plasmid-mediated quinolone resistance qnr genes in ESBL-producing enterobacterial isolates. J Antimicrob Chemother 2007, 60(2):394-397.
4. Compain F., Poisson A., Le Hello S., Branger C., Weill F.X., Arlet G., Decré D. Targeting relaxase genes for classification of the predominant plasmids in Enterobacteriaceae. Int J Med Microbiol IJMM 2014 May, 304(3-4):236-242.
5. Dallenne C., Da Costa A., Decré D., Favier C., Arlet G. Development of a set of multiplex PCR assays for the detection of genes encoding important beta-lactamases in Enterobacteriaceae. J Antimicrob Chemother 2010, 65(3):490-495.
6. Diancourt L., Passet V., Verhoef J., Grimont P.A., Brisse S. Multilocus sequence typing of Klebsiella pneumoniae nosocomial isolates. J Clin Microbiol 2005, 43(8):4178-4182.
7. Diestra K., Miró E., Martí C., Navarro D., Cuquet J., Coll P., Navarro F. Multiclonal epidemic of Klebsiella pneumoniae isolates producing DHA-1 in a Spanish hospital. Clin Microbiol Infect 2011, 17(7):1032-1036.
8. Empel J., Hrabák J., Kozińska A., Bergerová T., Urbášková P., Kern-Zdanowicz I., Gniadkowski M. DHA-1-producing Klebsiella pneumoniae in a teaching hospital in the Czech Republic. Microb Drug Resist 2010, 16(4):291-295.
9. García-Fernández A., Carattoli A. Plasmid double locus sequence typing for IncHI2 plasmids, a subtyping scheme for the characterization of IncHI2 plasmids carrying extended-spectrum beta-lactamase and quinolone resistance genes. J Antimicrob Chemother 2010, 65(6):1155-1161.
10. Hennequin C., Robin F., Cabrolier N., Bonnet R., Forestier C. Characterization of a DHA-1-producing Klebsiella pneumoniae strain involved in an outbreak and role of the AmpR regulator in virulence. Antimicrob Agents Chemother 2012, 56(1):288-294.
11. Hidalgo L., Gutierrez B., Ovejero C.M., Carrilero L., Matrat S., Saba C.K., Santos-Lopez A., Thomas-Lopez D., Hoefer A., Santurde G., Martin-Espada C., Gonzalez-Zorn B. Klebsiella pneumoniae ST11 from companion animals bearing ArmA methyltransferase, DHA-1 β-lactamase and QnrB4. Antimicrob Agents Chemother 2013, 57(9):4532-4534.
12. Iabadene H., Messai Y., Ammari H., Alouache S., Verdet C., Bakour R., Arlet G. Prevalence of plasmid-mediated AmpC beta-lactamases among Enterobacteriaceae in Algiers hospitals. Int J Antimicrob Agents 2009, 34(4):340-342.
13. Illiaquer M., Caroff N., Bémer P., Aubin G.G., Juvin M.E., Lepelletier D., Reynaud A., Corvec S. Occurrence and molecular characterization of Klebsiella pneumoniae ST37 clinical isolates producing plasmid-mediated AmpC recovered over a 3-year period. Diagn Microbiol Infect Dis 2012, 74(1):95-97.
14. Jacoby G.A. AmpC beta-lactamases. Clin Microbiol Rev 2009, 22(1):161-182.
15. Kado C.I., Liu S.T. Rapid procedure for detection and isolation of large and small plasmids. J Bacteriol 1981, 145(3):1365-1373.
16. Marcade G., Brisse S., Bialek S., Marcon E., Leflon-Guibout V., Passet V., Moreau R., Nicolas-Chanoine M.H. The emergence of multidrug-resistant Klebsiella pneumoniae of international clones ST13, ST16, ST35, ST48 and ST101 in a teaching hospital in the Paris region. Epidemiol Infect 2013, 141(8):1705-1712.
17. Mata C., Miró E., Alvarado A., Garcillán-Barcia M.P., Toleman M., Walsh T.R., de la Cruz F., Navarro F. Plasmid typing and genetic context of AmpC β-lactamases in Enterobacteriaceae lacking inducible chromosomal ampC genes: findings from a Spanish hospital 1999-2007. J Antimicrob Chemother 2012, 67(1):115-122.
18. Mata C., Miró E., Toleman M., Rivera M.A., Walsh T.R., Navarro F. Association of bla(DHA-1) and qnrB genes carried by broad-host-range plasmids among isolates of Enterobacteriaceae at a Spanish hospital. Clin Microbiol Infect 2011, 17(10):1514-1517.
19. Roche C., Boo T.W., Walsh F., Crowley B. Detection and molecular characterisation of plasmidic AmpC beta-lactamases in Klebsiella pneumoniae isolates from a tertiary-care hospital in Dublin, Ireland. Clin Microbiol Infect 2008, 14(6):616-618.
20. Roh K.H., Uh Y., Kim J.S., Kim H.S., Shin D.H., Song W. First outbreak of multidrug-resistant Klebsiella pneumoniae producing both SHV-12-type extended-spectrum beta-lactamase and DHA-1-type AmpC beta-lactamase at a Korean hospital. Yonsei Med J 2008, 49(1):53-57.
21. Shin S.Y., Bae I.K., Kim J., Jeong S.H., Yong D., Kim J.M., Lee K. Resistance to carbapenems in sequence type 11 Klebsiella pneumoniae is related to DHA-1 and loss of OmpK35 and/or OmpK36. J Med Microbiol 2012, 61(Pt. 2):239-245.
22. Song W., Lee K.M., Kim H.S., Kim J.S., Kim J., Jeong S.H., Roh K.H. Clonal spread of both oxyimino-cephalosporin- and cefoxitin-resistant Klebsiella pneumoniae isolates co-producing SHV-2a and DHA-1 beta-lactamase at a burns intensive care unit. Int J Antimicrob Agents 2006, 28(6):520-524.
23. Vanwynsberghe T., Verhamme K., Raymaekers M., Cartuyvels R., Boel A., De Beenhouwer H. Outbreak of Klebsiella pneumoniae strain harbouring an AmpC (DHA-1) and a blaSHV-11 in a Belgian hospital, August-December 2006. Euro Surveill 2007, 12(2):E070201.3.
24. Verdet C., Benzerara Y., Gautier V., Adam O., Ould-Hocine Z., Arlet G. Emergence of DHA-1-producing Klebsiella spp. in the Parisian region: genetic organization of the ampC and ampR genes originating from Morganella morganii. Antimicrob Agents Chemother 2006, 50(2):607-617.
25. Verdet C., Laouira S., Merens A., Vachée A., Arlet G., Robert J. Prévalence des souches productrices de céphalosporinases plasmidiques chez les entérobactéries des groupes 1 et 2 en France en 2009. 30th Réunion Interdisciplinaire de Chimiothérapie Anti Infectieuse (RICAI) 2010, on behalf of the Scientific Committee of ONERBA, [Abstr N508].
26. Versalovic J., Koeuth T., Lupski J.R. Distribution of repetitive DNA sequences in eubacteria and application to fingerprinting of bacterial genomes. Nucleic Acids Res 1991, 19:6823-6831.