Genomic and transcriptomic analyses of colistin-resistant clinical isolates of Klebsiella pneumoniae reveal multiple pathways of resistance

Antimicrobial Agents and Chemotherapy

Volumn 59, Issue 1, 2015, Pages 536-543

  Wright, Meredith S ^a   Suzuki, Yo ^a   Jones, Marcus B ^a   Marshall, Steven H ^b   Rudin, Susan D ^b   Van Duin, David ^c   Kaye, Keith ^d   Jacobs, Michael R ^e   Bonomo, Robert A ^b,f   Adamsa, Mark D ^a  

^a J CRAIG VENTER INSTITUTE   (United States)

^b LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d DETROIT MEDICAL CENTER   (United States)

^e CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 4 DEOXY LEVO ARABINOSE; ARABINOSE; COLISTIN; GLYCOSYLTRANSFERASE; LIPID A; LIPOPOLYSACCHARIDE; PHOSPHOETHANOLAMINE; PROTEIN HISTIDINE KINASE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN;

ALLELE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATION; CATION TRANSPORT; ESCHERICHIA COLI; GENE EXPRESSION PROFILING; GENE MUTATION; GENE SEQUENCE; GENOME ANALYSIS; GENOMICS; KLEBSIELLA PNEUMONIAE; MULTIDRUG RESISTANCE; NONHUMAN; OPERON; PROTEIN MODIFICATION; RNA SEQUENCE; SIGNAL TRANSDUCTION; TRANSCRIPTOMICS; UPREGULATION; BACTERIAL GENOME; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; MUTATION;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; COLISTIN; DRUG RESISTANCE, BACTERIAL; GENE EXPRESSION REGULATION, BACTERIAL; GENOME, BACTERIAL; HUMANS; KLEBSIELLA PNEUMONIAE; LIPID A; MUTATION; OPERON;

EID: 84920148701     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.04037-14     Document Type: Article

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