메뉴 건너뛰기




Volumn 30, Issue 5, 2016, Pages 567-578

Visualizing allele-specific expression in single cells reveals epigenetic mosaicism in an H19 loss-of-imprinting mutant

Author keywords

Gene expression; Imprinting; Single cell

Indexed keywords

SOMATOMEDIN B; H19 LONG NON-CODING RNA; LONG UNTRANSLATED RNA;

EID: 84959478135     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.275958.115     Document Type: Article
Times cited : (33)

References (38)
  • 1
    • 0037068379 scopus 로고    scopus 로고
    • 5-azacytidine and 5-aza-2'-deoxycytidine asinhibitors ofDNAmethylation: Mechanistic studies and theirimplications for cancer therapy
    • Christman JK. 2002. 5-azacytidine and 5-aza-2'-deoxycytidine asinhibitors ofDNAmethylation: mechanistic studies and theirimplications for cancer therapy. Oncogene 21: 5483-5495.
    • (2002) Oncogene , vol.21 , pp. 5483-5495
    • Christman, J.K.1
  • 2
    • 33646591544 scopus 로고    scopus 로고
    • Transcriptionalpulsing of a developmental gene
    • Chubb JR, Trcek T, Shenoy SM, Singer RH. 2006. Transcriptionalpulsing of a developmental gene. Curr Biol 16: 1018-1025.
    • (2006) Curr Biol , vol.16 , pp. 1018-1025
    • Chubb, J.R.1    Trcek, T.2    Shenoy, S.M.3    Singer, R.H.4
  • 3
    • 84892179132 scopus 로고    scopus 로고
    • Single-cellRNA-seq reveals dynamic, random monoallelic gene expressionin mammalian cells
    • Deng Q, Ramsköld D, Reinius B, Sandberg R. 2014. Single-cellRNA-seq reveals dynamic, random monoallelic gene expressionin mammalian cells. Science 343: 193-196.
    • (2014) Science , vol.343 , pp. 193-196
    • Deng, Q.1    Ramsköld, D.2    Reinius, B.3    Sandberg, R.4
  • 4
    • 84899980569 scopus 로고    scopus 로고
    • In vitro culture increasesthe frequency of stochastic epigenetic errors at imprintedgenes in placental tissues from mouse concepti producedthrough assisted reproductive technologies
    • de Waal E, Mak W, Calhoun S, Stein P, Ord T, Krapp C, Coutifaris C, Schultz RM, Bartolomei MS. 2014. In vitro culture increasesthe frequency of stochastic epigenetic errors at imprintedgenes in placental tissues from mouse concepti producedthrough assisted reproductive technologies. Biol Reprod 90:22-22.
    • (2014) Biol Reprod , vol.90 , pp. 22
    • de Waal, E.1    Mak, W.2    Calhoun, S.3    Stein, P.4    Ord, T.5    Krapp, C.6    Coutifaris, C.7    Schultz, R.M.8    Bartolomei, M.S.9
  • 5
    • 3543010196 scopus 로고    scopus 로고
    • Antagonismbetween DNA hypermethylation and enhancerblockingactivity at the H19 DMD is uncovered by CpG mutations
    • Engel N, West AG, Felsenfeld G, Bartolomei MS. 2004. Antagonismbetween DNA hypermethylation and enhancerblockingactivity at the H19 DMD is uncovered by CpG mutations.Nat Genet 36: 883-888.
    • (2004) Nat Genet , vol.36 , pp. 883-888
    • Engel, N.1    West, A.G.2    Felsenfeld, G.3    Bartolomei, M.S.4
  • 6
    • 1042278765 scopus 로고    scopus 로고
    • The history of cancer epigenetics
    • Feinberg AP, Tycko B. 2004. The history of cancer epigenetics.Nat Rev Cancer 4: 143-153.
    • (2004) Nat Rev Cancer , vol.4 , pp. 143-153
    • Feinberg, A.P.1    Tycko, B.2
  • 7
    • 77952700235 scopus 로고    scopus 로고
    • The H19 locus: Role of animprinted non-coding RNA in growth and development
    • Gabory A, Jammes H, Dandolo L. 2010. The H19 locus: role of animprinted non-coding RNA in growth and development. Bioessays32: 473-480.
    • (2010) Bioessays , vol.32 , pp. 473-480
    • Gabory, A.1    Jammes, H.2    Dandolo, L.3
  • 10
    • 28944434119 scopus 로고    scopus 로고
    • Real-time kineticsof gene activity in individual bacteria
    • Golding I, Paulsson J, Zawilski SM, Cox EC. 2005. Real-time kineticsof gene activity in individual bacteria. Cell 123:1025-1036.
    • (2005) Cell , vol.123 , pp. 1025-1036
    • Golding, I.1    Paulsson, J.2    Zawilski, S.M.3    Cox, E.C.4
  • 11
    • 0031952115 scopus 로고    scopus 로고
    • Imprinting of mouse Kvlqt1 is developmentallyregulated
    • Gould TD, Pfeifer K. 1998. Imprinting of mouse Kvlqt1 is developmentallyregulated. Hum Mol Genet 7: 483-487.
    • (1998) Hum Mol Genet , vol.7 , pp. 483-487
    • Gould, T.D.1    Pfeifer, K.2
  • 12
    • 84883447620 scopus 로고    scopus 로고
    • Allele-specific detectionof single mRNA molecules in situ
    • Hansen CH, van Oudenaarden A. 2013. Allele-specific detectionof single mRNA molecules in situ. Nat Methods 10: 869-871.
    • (2013) Nat Methods , vol.10 , pp. 869-871
    • Hansen, C.H.1    van Oudenaarden, A.2
  • 13
    • 84909618136 scopus 로고    scopus 로고
    • Tissue-specific insulator function at H19/Igf2 revealedby deletions at the imprinting control region
    • Ideraabdullah FY, Thorvaldsen JL, Myers JA, Bartolomei MS.2014. Tissue-specific insulator function at H19/Igf2 revealedby deletions at the imprinting control region. Hum Mol Genet23: 6246-6259.
    • (2014) Hum Mol Genet , vol.23 , pp. 6246-6259
    • Ideraabdullah, F.Y.1    Thorvaldsen, J.L.2    Myers, J.A.3    Bartolomei, M.S.4
  • 16
    • 84875177348 scopus 로고    scopus 로고
    • X-inactivation, imprinting, andlong noncoding RNAs in health and disease
    • Lee JT, Bartolomei MS. 2013. X-inactivation, imprinting, andlong noncoding RNAs in health and disease. Cell 152:1308-1323.
    • (2013) Cell , vol.152 , pp. 1308-1323
    • Lee, J.T.1    Bartolomei, M.S.2
  • 17
    • 84874665433 scopus 로고    scopus 로고
    • Single-chromosome transcriptionalprofiling reveals chromosomal gene expression regulation
    • Levesque MJ, Raj A. 2013. Single-chromosome transcriptionalprofiling reveals chromosomal gene expression regulation.Nat Methods 10: 246-248.
    • (2013) Nat Methods , vol.10 , pp. 246-248
    • Levesque, M.J.1    Raj, A.2
  • 18
    • 84883458433 scopus 로고    scopus 로고
    • Visualizing SNVs toquantify allele-specific expression in single cells
    • Levesque MJ, Ginart P, Wei Y, Raj A. 2013. Visualizing SNVs toquantify allele-specific expression in single cells. Nat Methods10: 865-867.
    • (2013) Nat Methods , vol.10 , pp. 865-867
    • Levesque, M.J.1    Ginart, P.2    Wei, Y.3    Raj, A.4
  • 20
    • 0042862983 scopus 로고    scopus 로고
    • Disruption of imprinted gene methylationand expression in cloned preimplantation stage mouse embryos
    • Mann MRW, Chung YG, Nolen LD, Verona RI, Latham KE, Bartolomei MS. 2003. Disruption of imprinted gene methylationand expression in cloned preimplantation stage mouse embryos.Biol Reprod 69: 902-914.
    • (2003) Biol Reprod , vol.69 , pp. 902-914
    • Mann, M.R.W.1    Chung, Y.G.2    Nolen, L.D.3    Verona, R.I.4    Latham, K.E.5    Bartolomei, M.S.6
  • 21
    • 77649289429 scopus 로고    scopus 로고
    • Dual effects of superovulation: Loss of maternaland paternal imprinted methylation in a dose-dependent manner
    • Market-Velker BA, Zhang L, Magri LS, Bonvissuto AC, Mann MRW. 2010. Dual effects of superovulation: loss of maternaland paternal imprinted methylation in a dose-dependent manner.Hum Mol Genet 19: 36-51.
    • (2010) Hum Mol Genet , vol.19 , pp. 36-51
    • Market-Velker, B.A.1    Zhang, L.2    Magri, L.S.3    Bonvissuto, A.C.4    Mann, M.R.W.5
  • 23
    • 53549123008 scopus 로고    scopus 로고
    • Nature, nurture, or chance:Stochastic gene expression and its consequences
    • Raj A, van Oudenaarden A. 2008. Nature, nurture, or chance:stochastic gene expression and its consequences. Cell 135:216-226.
    • (2008) Cell , vol.135 , pp. 216-226
    • Raj, A.1    van Oudenaarden, A.2
  • 26
    • 77249114260 scopus 로고    scopus 로고
    • Variabilityin gene expression underlies incomplete penetrance
    • Raj A, Rifkin SA, Andersen E, van Oudenaarden A. 2010. Variabilityin gene expression underlies incomplete penetrance. Nature463: 913-918.
    • (2010) Nature , vol.463 , pp. 913-918
    • Raj, A.1    Rifkin, S.A.2    Andersen, E.3    van Oudenaarden, A.4
  • 27
    • 84944441199 scopus 로고    scopus 로고
    • Random monoallelic expression ofautosomal genes: Stochastic transcription and allele-level regulation
    • Reinius B, Sandberg R. 2015. Random monoallelic expression ofautosomal genes: stochastic transcription and allele-level regulation.Nat Rev Genet 16: 653-664.
    • (2015) Nat Rev Genet , vol.16 , pp. 653-664
    • Reinius, B.1    Sandberg, R.2
  • 28
    • 84889589801 scopus 로고    scopus 로고
    • Autosomal monoallelicexpression: Genetics of epigenetic diversity?
    • Savova V, Vigneau S, Gimelbrant AA. 2013. Autosomal monoallelicexpression: genetics of epigenetic diversity? Curr OpinGenet Dev 23: 642-648.
    • (2013) Curr OpinGenet Dev , vol.23 , pp. 642-648
    • Savova, V.1    Vigneau, S.2    Gimelbrant, A.A.3
  • 32
    • 0036211514 scopus 로고    scopus 로고
    • Analysis of sequence upstream of the endogenousH19 gene reveals elements both essential and dispensablefor imprinting
    • Thorvaldsen JL, Mann MRW, Nwoko O, Duran KL, Bartolomei MS. 2002. Analysis of sequence upstream of the endogenousH19 gene reveals elements both essential and dispensablefor imprinting. Mol Cell Biol 22: 2450-2462.
    • (2002) Mol Cell Biol , vol.22 , pp. 2450-2462
    • Thorvaldsen, J.L.1    Mann, M.R.W.2    Nwoko, O.3    Duran, K.L.4    Bartolomei, M.S.5
  • 33
    • 32044441436 scopus 로고    scopus 로고
    • Developmental profile of H19 differentially methylateddomain (DMD) deletion alleles reveals multiple roles ofthe DMD in regulating allelic expression and DNA methylationat the imprinted H19/Igf2 locus
    • Thorvaldsen JL, Fedoriw AM, Nguyen S, Bartolomei MS. 2006.Developmental profile of H19 differentially methylateddomain (DMD) deletion alleles reveals multiple roles ofthe DMD in regulating allelic expression and DNA methylationat the imprinted H19/Igf2 locus. Mol Cell Biol 26:1245-1258.
    • (2006) Mol Cell Biol , vol.26 , pp. 1245-1258
    • Thorvaldsen, J.L.1    Fedoriw, A.M.2    Nguyen, S.3    Bartolomei, M.S.4
  • 34
    • 0030802395 scopus 로고    scopus 로고
    • A 5' 2-kilobasepairregion of the imprinted mouse H19 gene exhibits exclusivepaternal methylation throughout development
    • Tremblay KD, Duran KL, Bartolomei MS. 1997. A 5' 2-kilobasepairregion of the imprinted mouse H19 gene exhibits exclusivepaternal methylation throughout development. MolCell Biol 17: 4322-4329.
    • (1997) MolCell Biol , vol.17 , pp. 4322-4329
    • Tremblay, K.D.1    Duran, K.L.2    Bartolomei, M.S.3
  • 35
    • 84877258652 scopus 로고    scopus 로고
    • Imprinted genes in mouseplacental development and the regulation of fetal energystores
    • Tunster SJ, Jensen AB, John RM. 2013. Imprinted genes in mouseplacental development and the regulation of fetal energystores. Reproduction 145: R117-R137.
    • (2013) Reproduction , vol.145 , pp. R117-R137
    • Tunster, S.J.1    Jensen, A.B.2    John, R.M.3
  • 36
    • 37549006834 scopus 로고    scopus 로고
    • Thetranscriptional status but not the imprinting control regiondetermines allele-specific histone modifications at the imprintedH19 locus
    • Verona RI, Thorvaldsen JL, Reese KJ, Bartolomei MS. 2008. Thetranscriptional status but not the imprinting control regiondetermines allele-specific histone modifications at the imprintedH19 locus. Mol Cell Biol 28: 71-82.
    • (2008) Mol Cell Biol , vol.28 , pp. 71-82
    • Verona, R.I.1    Thorvaldsen, J.L.2    Reese, K.J.3    Bartolomei, M.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.