Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria

Journal of Cell Biology

Volumn 212, Issue 2, 2016, Pages 157-166

  Korwitz, Anne ^a   Merkwirth, Carsten ^a   Richter Dennerlein, Ricarda ^a   Tröder, Simon E ^a   Sprenger, Hans Georg ^a   Quirós, Pedro M ^b   López Otín, Carlos ^b   Rugarli, Elena I ^a   Langer, Thomas ^a,c  

^a UNIVERSITY OF COLOGNE   (Germany)

^b DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

^c MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE; MITOCHONDRIAL DNA; OMA1 PROTEIN; OPA1 PROTEIN; UNCLASSIFIED DRUG; METALLOPROTEINASE; MITOCHONDRIAL PROTEIN; OMA1 PROTEIN, MOUSE; OPA1 PROTEIN (GTPASE), MOUSE; PROHIBITIN; REPRESSOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN WEIGHT; CELL STRESS; CELL SURVIVAL; CELL ULTRASTRUCTURE; CONTROLLED STUDY; ENZYME ACTIVATION; HIPPOCAMPUS; IN VIVO STUDY; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL VOLUME; MITOCHONDRION; MITOPHAGY; MOUSE; NECROPTOSIS; NERVE CELL NECROSIS; NERVE DEGENERATION; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PROCESSING; RESPIRATORY FUNCTION; ANIMAL; BRAIN; C57BL MOUSE; CELL CULTURE; CELL RESPIRATION; GENE DELETION; GENETICS; METABOLISM; NERVE CELL; PATHOLOGY;

ANIMALS; APOPTOSIS; BRAIN; CELL RESPIRATION; CELL SURVIVAL; CELLS, CULTURED; DNA, MITOCHONDRIAL; GENE DELETION; GTP PHOSPHOHYDROLASES; METALLOPROTEASES; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NERVE DEGENERATION; NEURONS; REPRESSOR PROTEINS;

EID: 84959453982     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201507022     Document Type: Article

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