OMA1 mediates OPA1 proteolysis and mitochondrial fragmentation in experimental models of ischemic kidney injury

American Journal of Physiology - Renal Physiology

Volumn 306, Issue 11, 2014, Pages

  Xiao, Xiao ^a,c   Hu, Yanzhong ^b   Quirós, Pedro M ^d   Wei, Qingqing ^a   López Otín, Carlos ^d   Dong, Zheng ^a,b  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b HENAN UNIVERSITY   (China)

^c WUHAN UNIVERSITY   (China)

^d DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

Author keywords

Acute kidney injury; Apoptosis; Ischemia reperfusion; Mitochondria

Indexed keywords

ADENOSINE TRIPHOSPHATE; AZIDE; CYTOCHROME C; MEMBRANE FUSION PROTEIN; METALLOPROTEINASE; OMA 1 PROTEIN; OPA 1 PROTEIN; UNCLASSIFIED DRUG;

ACUTE KIDNEY FAILURE; ALTERNATIVE RNA SPLICING; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL STRESS; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; KIDNEY CELL; KIDNEY FUNCTION; KIDNEY ISCHEMIA; KIDNEY PARENCHYMA; MALE; MEMBRANE FUSION; MITOCHONDRIAL DYNAMICS; MOUSE; NONHUMAN; OUTER MEMBRANE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECRETION;

ACUTE KIDNEY INJURY; APOPTOSIS; ISCHEMIA-REPERFUSION; MITOCHONDRIA;

ACUTE KIDNEY INJURY; ANIMALS; CELL LINE; DISEASE MODELS, ANIMAL; GTP PHOSPHOHYDROLASES; ISCHEMIA; KIDNEY; MALE; METALLOPROTEASES; MICE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; PROTEOLYSIS; RATS;

EID: 84901712100     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00036.2014     Document Type: Article

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