-
1
-
-
84892805731
-
Cancer statistics 2014
-
Siegel R, Ma J, Zou Z, Jemal A. Cancer statistics, 2014. CA Cancer J. Clin. 64(1), 9-29 (2014
-
(2014)
CA Cancer J. Clin
, vol.64
, Issue.1
, pp. 9-29
-
-
Siegel, R.1
Ma, J.2
Zou, Z.3
Jemal, A.4
-
3
-
-
84905975277
-
B7-H1/PD-1 blockade therapy in non-small cell lung cancer: Current status and future direction
-
Gettinger S, Herbst RS. B7-H1/PD-1 blockade therapy in non-small cell lung cancer: current status and future direction. Cancer J. 20(4), 281-289 (2014
-
(2014)
Cancer J.
, vol.20
, Issue.4
, pp. 281-289
-
-
Gettinger, S.1
Herbst, R.S.2
-
4
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
Sandler A, Gray R, Perry MC, et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N. Engl. J.Med. 355(24), 2542-2550 (2006
-
(2006)
N. Engl. J.Med
, vol.355
, Issue.24
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
-
5
-
-
33947498978
-
Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer
-
Sequist LV, Bell DW, Lynch TJ, Haber DA. Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer. J.Clin. Oncol. 25(5), 587-595 (2007
-
(2007)
J.Clin. Oncol
, vol.25
, Issue.5
, pp. 587-595
-
-
Sequist, L.V.1
Bell, D.W.2
Lynch, T.J.3
Haber, D.A.4
-
6
-
-
84923011927
-
EGFR T790M resistance mutation in non small-cell lung carcinoma
-
Denis MG, Vallée A, Théoleyre S. EGFR T790M resistance mutation in non small-cell lung carcinoma. Clin. Chim. Acta 444, 81-85 (2015
-
(2015)
Clin. Chim. Acta
, vol.444
, pp. 81-85
-
-
Denis, M.G.1
Vallée, A.2
Théoleyre, S.3
-
7
-
-
84923611342
-
Prevalence and natural history of ALK positive nonsmall-cell lung cancer and the clinical impact of targeted therapy with ALK inhibitors
-
Chia PL, Mitchell P, Dobrovic A, John T. Prevalence and natural history of ALK positive nonsmall-cell lung cancer and the clinical impact of targeted therapy with ALK inhibitors. Clin. Epidemiol. 6, 423-432 (2014
-
(2014)
Clin. Epidemiol
, vol.6
, pp. 423-432
-
-
Chia, P.L.1
Mitchell, P.2
Dobrovic, A.3
John, T.4
-
8
-
-
70349336416
-
Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK
-
Shaw AT, Yeap BY, Mino-Kenudson M, et al. Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK. J.Clin. Oncol. 27(26), 4247-4253 (2009
-
(2009)
J.Clin. Oncol
, vol.27
, Issue.26
, pp. 4247-4253
-
-
Shaw, A.T.1
Yeap, B.Y.2
Mino-Kenudson, M.3
-
9
-
-
37549057005
-
The anaplastic lymphoma kinase in the pathogenesis of cancer
-
Chiarle R, Voena C, Ambrogio C, Piva R, Inghirami G. The anaplastic lymphoma kinase in the pathogenesis of cancer. Nat. Rev. Cancer 8(1), 11-23 (2008
-
(2008)
Nat. Rev. Cancer
, vol.8
, Issue.1
, pp. 11-23
-
-
Chiarle, R.1
Voena, C.2
Ambrogio, C.3
Piva, R.4
Inghirami, G.5
-
10
-
-
48249114422
-
EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer
-
Koivunen JP, Mermel C, Zejnullahu K, et al. EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clin. Cancer. Res. 14(13), 4275-4283 (2008
-
(2008)
Clin. Cancer. Res
, vol.14
, Issue.13
, pp. 4275-4283
-
-
Koivunen, J.P.1
Mermel, C.2
Zejnullahu, K.3
-
11
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat. Rev. Cancer 12(4), 252-264 (2012
-
(2012)
Nat. Rev. Cancer
, vol.12
, Issue.4
, pp. 252-264
-
-
Pardoll, D.M.1
-
12
-
-
84928062583
-
Immune checkpoint blockade: A common denominator approach to cancer therapy
-
Topalian SL, Drake CG, Pardoll DM. Immune checkpoint blockade: a common denominator approach to cancer therapy. Cancer Cell 27(4), 450-461 (2015
-
(2015)
Cancer Cell
, vol.27
, Issue.4
, pp. 450-461
-
-
Topalian, S.L.1
Drake, C.G.2
Pardoll, D.M.3
-
13
-
-
84929456860
-
Cancer immunotherapy: A future paradigm shift in the treatment of non-small-cell lung cancer
-
Anagnostou VK, Brahmer JR. Cancer immunotherapy: a future paradigm shift in the treatment of non-small-cell lung cancer. Clin. Cancer. Res. 21(5), 976-984 (2015
-
(2015)
Clin. Cancer. Res
, vol.21
, Issue.5
, pp. 976-984
-
-
Anagnostou, V.K.1
Brahmer, J.R.2
-
15
-
-
84905982850
-
Inducible expression of B7-H1 (PDL1) and its selective role in tumor site immune modulation
-
Sanmamed MF, Chen L. Inducible expression of B7-H1 (PDL1) and its selective role in tumor site immune modulation. Cancer J. 20(4), 256-261 (2014
-
(2014)
Cancer J.
, vol.20
, Issue.4
, pp. 256-261
-
-
Sanmamed, M.F.1
Chen, L.2
-
16
-
-
0029947568
-
Enhancement of antitumor immunity by CTLA-4 blockade
-
Leach DR, Krummel MF, Allison JP. Enhancement of antitumor immunity by CTLA-4 blockade. Science 271(5256), 1734-1736 (1996
-
(1996)
Science
, vol.271
, Issue.5256
, pp. 1734-1736
-
-
Leach, D.R.1
Krummel, M.F.2
Allison, J.P.3
-
17
-
-
0037126021
-
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
-
Iwai Y, Ishida M, Tanaka Y, Okazaki T, Honjo T, Minato N. Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc. Natl Acad. Sci. USA 99(19), 12293-12297 (2002
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, Issue.19
, pp. 12293-12297
-
-
Iwai, Y.1
Ishida, M.2
Tanaka, Y.3
Okazaki, T.4
Honjo, T.5
Minato, N.6
-
18
-
-
65349119978
-
CD28 and CTLA-4 coreceptor expression and signal transduction
-
Rudd CE, Taylor A, Schneider H. CD28 and CTLA-4 coreceptor expression and signal transduction. Immunol. Rev. 229(1), 12-26 (2009
-
(2009)
Immunol. Rev
, vol.229
, Issue.1
, pp. 12-26
-
-
Rudd, C.E.1
Taylor, A.2
Schneider, H.3
-
19
-
-
0025979295
-
Cd28 and Ctla-4, two related members of the Ig supergene family, are tightly linked on proximal mouse chromosome 1
-
Howard TA, Rochelle JM, Seldin MF Cd28 and Ctla-4, two related members of the Ig supergene family, are tightly linked on proximal mouse chromosome 1. Immunogenetics 33(1), 74-76 (1991
-
(1991)
Immunogenetics
, vol.33
, Issue.1
, pp. 74-76
-
-
Howard, T.A.1
Rochelle, J.M.2
Seldin, M.F.3
-
20
-
-
0033792862
-
The CTLA4/CD28 gene region on chromosome 2q33 confers susceptibility to celiac disease in a way possibly distinct from that of type 1 diabetes and other chronic inflammatory disorders
-
Naluai AT, Nilsson S, Samuelsson L, et al. The CTLA4/CD28 gene region on chromosome 2q33 confers susceptibility to celiac disease in a way possibly distinct from that of type 1 diabetes and other chronic inflammatory disorders. Tissue Antigens 56(4), 350-355 (2000
-
(2000)
Tissue Antigens
, vol.56
, Issue.4
, pp. 350-355
-
-
Naluai, A.T.1
Nilsson, S.2
Samuelsson, L.3
-
21
-
-
0031054242
-
CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics
-
Van Der Merwe PA, Bodian DL, Daenke S, Linsley P, Davis SJ. CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics. J.Exp. Med. 185(3), 393-403 (1997
-
(1997)
J.Exp. Med
, vol.185
, Issue.3
, pp. 393-403
-
-
Van Der Merwe, P.A.1
Bodian, D.L.2
Daenke, S.3
Linsley, P.4
Davis, S.J.5
-
22
-
-
0028979466
-
New perspectives of CD28-B7-mediated T cell costimulation
-
Bluestone JA. New perspectives of CD28-B7-mediated T cell costimulation. Immunity 2(6), 555-559 (1995
-
(1995)
Immunity
, vol.2
, Issue.6
, pp. 555-559
-
-
Bluestone, J.A.1
-
23
-
-
0029117327
-
Distinct roles for CD28 and cytotoxic T lymphocyte-Associated molecule-4 receptors during T cell activation?
-
Linsley PS. Distinct roles for CD28 and cytotoxic T lymphocyte-Associated molecule-4 receptors during T cell activation?. J. Exp. Med. 182(2), 289-292 (1995
-
(1995)
J. Exp. Med
, vol.182
, Issue.2
, pp. 289-292
-
-
Linsley, P.S.1
-
25
-
-
0027936441
-
AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes
-
Rincon M, Flavell RA. AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes. EMBO J. 13(18), 4370-4381 (1994
-
(1994)
EMBO J.
, vol.13
, Issue.18
, pp. 4370-4381
-
-
Rincon, M.1
Flavell, R.A.2
-
26
-
-
0031842613
-
Mechanism responsible for T-cell antigen receptor-And CD28-or interleukin 1 (IL-1) receptor-initiated regulation of IL-2 gene expression by NF-kappaB
-
Kalli K, Huntoon C, Bell M, Mckean DJ. Mechanism responsible for T-cell antigen receptor-And CD28-or interleukin 1 (IL-1) receptor-initiated regulation of IL-2 gene expression by NF-kappaB. Mol. Cell. Biol. 18(6), 3140-3148 (1998
-
(1998)
Mol. Cell. Biol
, vol.18
, Issue.6
, pp. 3140-3148
-
-
Kalli, K.1
Huntoon, C.2
Bell, M.3
Mckean, D.J.4
-
27
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-[kappa]
-
Karin M, Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu. Rev. Immunol. 18 621-663 (2000
-
(2000)
B Activity. Annu. Rev. Immunol
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
28
-
-
0142259712
-
Unifying concepts in CD28 ICOS and CTLA4 co-receptor signalling
-
Rudd CE, Schneider H. Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling. Nat. Rev. Immunol. 3(7), 544-556 (2003
-
(2003)
Nat. Rev. Immunol
, vol.3
, Issue.7
, pp. 544-556
-
-
Rudd, C.E.1
Schneider, H.2
-
29
-
-
68149155982
-
Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies
-
Peggs KS, Quezada SA, Chambers CA, Korman AJ, Allison JP. Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies. J. Exp. Med. 206(8), 1717-1725 (2009
-
(2009)
J. Exp. Med
, vol.206
, Issue.8
, pp. 1717-1725
-
-
Peggs, K.S.1
Quezada, S.A.2
Chambers, C.A.3
Korman, A.J.4
Allison, J.P.5
-
30
-
-
84884561907
-
Molecular pathways: Coexpression of immune checkpoint molecules: Signaling pathways and implications for cancer immunotherapy
-
Nirschl CJ, Drake CG. Molecular pathways: coexpression of immune checkpoint molecules: signaling pathways and implications for cancer immunotherapy. Clin. Cancer. Res. 19(18), 4917-4924 (2013
-
(2013)
Clin. Cancer. Res
, vol.19
, Issue.18
, pp. 4917-4924
-
-
Nirschl, C.J.1
Drake, C.G.2
-
31
-
-
0030001318
-
Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4
-
Marengere LE, Waterhouse P, Duncan GS, Mittrucker HW, Feng GS, Mak TW Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4. Science 272(5265), 1170-1173 (1996
-
(1996)
Science
, vol.272
, Issue.5265
, pp. 1170-1173
-
-
Marengere, L.E.1
Waterhouse, P.2
Duncan, G.S.3
Mittrucker, H.W.4
Feng, G.S.5
Mak, T.W.6
-
32
-
-
0033662376
-
The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A
-
Chuang E, Fisher TS, Morgan RW, et al The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A. Immunity 13(3), 313-322 (2000
-
(2000)
Immunity
, vol.13
, Issue.3
, pp. 313-322
-
-
Chuang, E.1
Fisher, T.S.2
Morgan, R.W.3
-
33
-
-
27144496045
-
CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms
-
Parry RV, Chemnitz JM, Frauwirth KA, et al. CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms. Mol. Cell. Biol. 25(21), 9543-9553 (2005
-
(2005)
Mol. Cell. Biol
, vol.25
, Issue.21
, pp. 9543-9553
-
-
Parry, R.V.1
Chemnitz, J.M.2
Frauwirth, K.A.3
-
34
-
-
84864438734
-
Ipilimumab: Its potential in non-small cell lung cancer
-
Tomasini P, Khobta N, Greillier L, Barlesi F. Ipilimumab: its potential in non-small cell lung cancer. Ther. Adv. Med. Oncol. 4(2), 43-50 (2012
-
(2012)
Ther. Adv. Med. Oncol
, vol.4
, Issue.2
, pp. 43-50
-
-
Tomasini, P.1
Khobta, N.2
Greillier, L.3
Barlesi, F.4
-
35
-
-
84918576077
-
Regulatory T cells control antigen-specific expansion of Tfh cell number and humoral immune responses via the coreceptor CTLA-4
-
Wing JB, Ise W, Kurosaki T, Sakaguchi S Regulatory T cells control antigen-specific expansion of Tfh cell number and humoral immune responses via the coreceptor CTLA-4. Immunity 41(6), 1013-1025 (2014
-
(2014)
Immunity
, vol.41
, Issue.6
, pp. 1013-1025
-
-
Wing, J.B.1
Ise, W.2
Kurosaki, T.3
Sakaguchi, S.4
-
36
-
-
53749094183
-
CTLA-4 control over Foxp3+ regulatory T cell function
-
Wing K, Onishi Y, Prieto-Martin P, et al. CTLA-4 control over Foxp3+ regulatory T cell function. Science 322(5899), 271-275 (2008
-
(2008)
Science
, vol.322
, Issue.5899
, pp. 271-275
-
-
Wing, K.1
Onishi, Y.2
Prieto-Martin, P.3
-
37
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'day SJ, Mcdermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J.Med. 363(8), 711-723 (2010
-
(2010)
N. Engl. J.Med
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
Mcdermott, D.F.3
-
38
-
-
84863911486
-
Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: Results from a randomized, double-blind, multicenter Phase II study
-
Lynch TJ, Bondarenko I, Luft A, et al. Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter Phase II study. J.Clin. Oncol. 30(17), 2046-2054 (2012
-
(2012)
J.Clin. Oncol
, vol.30
, Issue.17
, pp. 2046-2054
-
-
Lynch, T.J.1
Bondarenko, I.2
Luft, A.3
-
39
-
-
78449250123
-
Clinical development of the anti-CTLA-4 antibody tremelimumab
-
Ribas A. Clinical development of the anti-CTLA-4 antibody tremelimumab. Semin. Oncol. 37(5), 450-454 (2010
-
(2010)
Semin. Oncol
, vol.37
, Issue.5
, pp. 450-454
-
-
Ribas, A.1
-
40
-
-
84930889437
-
Immunotherapy for lung cancer: For whom the bell tolls?
-
Madureira P, De Mello RA, De Vasconcelos A, Zhang Y. Immunotherapy for lung cancer: for whom the bell tolls?. Tumour Biol. 36(3), 1411-1422 (2015
-
(2015)
Tumour Biol
, vol.36
, Issue.3
, pp. 1411-1422
-
-
Madureira, P.1
De Mello, R.A.2
De Vasconcelos, A.3
Zhang, Y.4
-
41
-
-
84959416011
-
-
Presented at: 45th Annual Meeting of the American Society of Clinical Oncology. Orlando, FL, USA, 29 May-2 June
-
Zatloukal P, Heo D, Park K, et al. Randomized Phase II clinical trial comparing tremelimumab (CP-675, 206) with best supportive care (BSC) following first-line platinumbased therapy in patients (pts) with advanced non-small cell lung cancer (NSCLC). Presented at: 45th Annual Meeting of the American Society of Clinical Oncology. Orlando, FL, USA, 29 May-2 June 2009
-
(2009)
Randomized Phase II Clinical Trial Comparing Tremelimumab (CP-675 206) with Best Supportive Care (BSC) Following First-line Platinumbased Therapy in Patients (Pts) with Advanced Non-small Cell Lung Cancer (NSCLC)
-
-
Zatloukal, P.1
Heo, D.2
Park, K.3
-
42
-
-
80051619906
-
The PD-L1: B7-1 pathway restrains diabetogenic effector T cells in vivo
-
Paterson AM, Brown KE, Keir ME, et al. The PD-L1: B7-1 pathway restrains diabetogenic effector T cells in vivo. J. Immunol. 187(3), 1097-1105 (2011
-
(2011)
J. Immunol
, vol.187
, Issue.3
, pp. 1097-1105
-
-
Paterson, A.M.1
Brown, K.E.2
Keir, M.E.3
-
43
-
-
84890020587
-
Activation of the PD-1 pathway contributes to immune escape in EGFRdriven lung tumors
-
Akbay EA, Koyama S, Carretero J, et al. Activation of the PD-1 pathway contributes to immune escape in EGFRdriven lung tumors. Cancer Discov. 3(12), 1355-1363 (2013
-
(2013)
Cancer Discov
, vol.3
, Issue.12
, pp. 1355-1363
-
-
Akbay, E.A.1
Koyama, S.2
Carretero, J.3
-
44
-
-
84938289871
-
Up-regulation of PD-L1 by EGFR activation mediates the immune escape in EGFRdriven NSCLC: Implication for optional immune targeted therapy for NSCLC patients with EGFR mutation
-
Chen N, Fang W, Zhan J, et al. Up-regulation of PD-L1 by EGFR activation mediates the immune escape in EGFRdriven NSCLC: Implication for optional immune targeted therapy for NSCLC patients with EGFR mutation. J. Thorac. Oncol. 10(6), 910-923 (2015
-
(2015)
J. Thorac. Oncol
, vol.10
, Issue.6
, pp. 910-923
-
-
Chen, N.1
Fang, W.2
Zhan, J.3
-
45
-
-
3142688997
-
SHP-1 and SHP-2 associate with immunoreceptor tyrosinebased switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation
-
Chemnitz JM, Parry RV, Nichols KE, June CH, Riley JL. SHP-1 and SHP-2 associate with immunoreceptor tyrosinebased switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation. J. Immunol. 173(2), 945-954 (2004
-
(2004)
J. Immunol
, vol.173
, Issue.2
, pp. 945-954
-
-
Chemnitz, J.M.1
Parry, R.V.2
Nichols, K.E.3
June, C.H.4
Riley, J.L.5
-
46
-
-
4444317516
-
PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3 signalosome and downstream signaling to PKC0
-
Sheppard K-A, Fitz LJ, Lee JM, et al. PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3 signalosome and downstream signaling to PKC0. FEBS Lett. 574(1), 37-41 (2004
-
(2004)
FEBS Lett
, vol.574
, Issue.1
, pp. 37-41
-
-
Sheppard, K.-A.1
Fitz, L.J.2
Lee, J.M.3
-
47
-
-
65349118810
-
PD-1 signaling in primary T cells
-
Riley JL. PD-1 signaling in primary T cells. Immunol. Rev. 229(1), 114-125 (2009
-
(2009)
Immunol. Rev
, vol.229
, Issue.1
, pp. 114-125
-
-
Riley, J.L.1
-
48
-
-
0041845131
-
Blockade of programmed death-1 engagement accelerates graft-versus-host disease lethality by an IFN-?-dependent mechanism
-
Blazar BR, Carreno BM, Panoskaltsis-Mortari A, et al. Blockade of programmed death-1 engagement accelerates graft-versus-host disease lethality by an IFN-?-dependent mechanism. J. Immunol. 171(3), 1272-1277 (2003
-
(2003)
J. Immunol
, vol.171
, Issue.3
, pp. 1272-1277
-
-
Blazar, B.R.1
Carreno, B.M.2
Panoskaltsis-Mortari, A.3
-
49
-
-
84945293157
-
Clinical evaluation of compounds targeting PD-1/PD-L1 pathway for cancer immunotherapy
-
Lu J, Lee-Gabel L, Nadeau MC, Ferencz TM, Soefje SA. Clinical evaluation of compounds targeting PD-1/PD-L1 pathway for cancer immunotherapy. J. Oncol. Pharm. Pract. 21(6), 451-467 (2014
-
(2014)
J. Oncol. Pharm. Pract
, vol.21
, Issue.6
, pp. 451-467
-
-
Lu, J.1
Lee-Gabel, L.2
Nadeau, M.C.3
Ferencz, T.M.4
Soefje, S.A.5
-
51
-
-
84937513626
-
A Phase III study (CheckMate 017) of nivolumab (NIVO; Anti-programmed death-1 [PD-1] vs docetaxel (DOC) in previously treated advanced or metastatic squamous (SQ) cell non-small-cell lung cancer (NSCLC)
-
Spigel DR, Reckamp KL, Rizvi NA, et al. A Phase III study (CheckMate 017) of nivolumab (NIVO; anti-programmed death-1 [PD-1]) vs docetaxel (DOC) in previously treated advanced or metastatic squamous (SQ) cell non-small-cell lung cancer (NSCLC). ASCO Meeting Abstracts 33(SUPPL 15), 8009 (2015
-
(2015)
ASCO Meeting Abstracts
, vol.33
, Issue.SUPPL. 15
, pp. 8009
-
-
Spigel, D.R.1
Reckamp, K.L.2
Rizvi, N.A.3
-
52
-
-
84936791837
-
Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer
-
Brahmer J, Reckamp KL, Baas P, et al. Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer. N. Engl. J.Med. 373(2), 123-135 (2015
-
(2015)
N. Engl. J.Med
, vol.373
, Issue.2
, pp. 123-135
-
-
Brahmer, J.1
Reckamp, K.L.2
Baas, P.3
-
53
-
-
84931424042
-
Phase III randomized trial (CheckMate 057) of nivolumab (NIVO) versus docetaxel (DOC) in advanced non-squamous cell (non-SQ) non-small cell lung cancer (NSCLC)
-
Paz-Ares L, Horn L, Borghaei H, et al. Phase III, randomized trial (CheckMate 057) of nivolumab (NIVO) versus docetaxel (DOC) in advanced non-squamous cell (non-SQ) non-small cell lung cancer (NSCLC). ASCO Meeting Abstracts 33(SUPPL 18), LBA109 (2015
-
(2015)
ASCO Meeting Abstracts
, vol.33
, Issue.SUPPL. 18
, pp. LBA109
-
-
Paz-Ares, L.1
Horn, L.2
Borghaei, H.3
-
54
-
-
84897040833
-
A Phase III comparative study of nivolumab (anti-PD-1; BMS-963558; ONO-4538 versus docetaxel in patients (pts) with previously treated advanced/metastatic nonsquamous nonsmall-cell lung cancer (NSCLC)
-
Gettinger SN, Brahmer JR, Rizvi NA, et al. A Phase III comparative study of nivolumab (anti-PD-1; BMS-963558; ONO-4538) versus docetaxel in patients (pts) with previously treated advanced/metastatic nonsquamous nonsmall-cell lung cancer (NSCLC). ASCO Meeting Abstracts 31(SUPPL 15), TPS8121 (2013
-
(2013)
ASCO Meeting Abstracts
, vol.31
, Issue.SUPPL. 15
, pp. TPS8121
-
-
Gettinger, S.N.1
Brahmer, J.R.2
Rizvi, N.A.3
-
55
-
-
84944937210
-
Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer
-
Borghaei H, Paz-Ares L, Horn L, et al. Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. N. Engl. J.Med. 373(17), 1627-1639 (2015
-
(2015)
N. Engl. J.Med
, vol.373
, Issue.17
, pp. 1627-1639
-
-
Borghaei, H.1
Paz-Ares, L.2
Horn, L.3
-
56
-
-
84959416012
-
Longer-Term follow-up of a phase 2 study (CheckMate 063) of nivolumab in patients with advanced, refractory squamous non-small-cell lung cancer
-
CO, USA 6-9 September
-
Horn L RN, Mazières J, et al. Longer-Term follow-up of a phase 2 study (CheckMate 063) of nivolumab in patients with advanced, refractory squamous non-small-cell lung cancer. Presented at: 16th World Conference on Lung Cancer Denver, CO, USA, 6-9 September 2015
-
(2015)
Presented At: 16th World Conference on Lung Cancer Denver
-
-
Horn, L.R.N.1
Mazières, J.2
-
57
-
-
84947439090
-
First-line monotherapy with nivolumab (NIVO; Anti-programmed death-1 [PD-1]) in advanced non-small-cell lung cancer (NSCLC): Safety efficacy and correlation of outcomes with PD-1 ligand (PD-L1) expression
-
Gettinger SN, Hellmann MD, Shepherd FA, et al. First-line monotherapy with nivolumab (NIVO; anti-programmed death-1 [PD-1]) in advanced non-small-cell lung cancer (NSCLC): safety, efficacy and correlation of outcomes with PD-1 ligand (PD-L1) expression. ASCO Meeting Abstracts 33(SUPPL 15), 8025 (2015
-
(2015)
ASCO Meeting Abstracts
, vol.33
, Issue.SUPPL. 15
, pp. 8025
-
-
Gettinger, S.N.1
Hellmann, M.D.2
Shepherd, F.A.3
-
59
-
-
84929481480
-
Pembrolizumab for the treatment of non-small-cell lung cancer
-
Garon EB, Rizvi NA, Hui R, et al. Pembrolizumab for the treatment of non-small-cell lung cancer. N. Engl. J. Med. 372(21), 2018-2028 (2015
-
(2015)
N. Engl. J. Med
, vol.372
, Issue.21
, pp. 2018-2028
-
-
Garon, E.B.1
Rizvi, N.A.2
Hui, R.3
-
60
-
-
84907614647
-
Safety and clinical activity of MK-3475 in previously treated patients (pts with non-small-cell lung cancer (NSCLC)
-
Garon EB, Leighl NB, Rizvi NA, et al. Safety and clinical activity of MK-3475 in previously treated patients (pts) with non-small-cell lung cancer (NSCLC). ASCO Meeting Abstracts 32(SUPPL 15), 8020 (2014
-
(2014)
ASCO Meeting Abstracts
, vol.32
, Issue.SUPPL. 15
, pp. 8020
-
-
Garon, E.B.1
Leighl, N.B.2
Rizvi, N.A.3
-
62
-
-
84960187594
-
Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): A randomised controlled trial
-
Herbst RS Baas P Kim DW, et al Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial The Lancet. http://www.thelancet.com
-
Lancet
-
-
Herbst, R.S.1
Baas, P.2
Kim, D.W.3
-
63
-
-
84942138571
-
Activity and safety of pembrolizumab in patients with metastatic non-small-cell lung cancer with untreated brain metastases
-
Goldberg SB, Gettinger SN, Mahajan A, et al. Activity and safety of pembrolizumab in patients with metastatic non-small-cell lung cancer with untreated brain metastases. ASCO Meeting Abstracts 33(SUPPL 15), 8035 (2015
-
(2015)
ASCO Meeting Abstracts
, vol.33
, Issue.SUPPL. 15
, pp. 8035
-
-
Goldberg, S.B.1
Gettinger, S.N.2
Mahajan, A.3
-
64
-
-
84920956735
-
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
-
Herbst RS, Soria JC, Kowanetz M, et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature 515(7528), 563-567 (2014
-
(2014)
Nature
, vol.515
, Issue.7528
, pp. 563-567
-
-
Herbst, R.S.1
Soria, J.C.2
Kowanetz, M.3
-
65
-
-
36049010929
-
B7-DC induced by IL-13 works as a feedback regulator in the effector phase of allergic asthma
-
Matsumoto K, Fukuyama S, Eguchi-Tsuda M, et al. B7-DC induced by IL-13 works as a feedback regulator in the effector phase of allergic asthma. Biochem. Biophys. Res. Commun. 365(1), 170-175 (2008
-
(2008)
Biochem. Biophys. Res. Commun
, vol.365
, Issue.1
, pp. 170-175
-
-
Matsumoto, K.1
Fukuyama, S.2
Eguchi-Tsuda, M.3
-
66
-
-
77249095138
-
PD-L1 and PD-L2 modulate airway inflammation and iNKT-cell-dependent airway hyperreactivity in opposing directions
-
Akbari O, Stock P, Singh AK, et al. PD-L1 and PD-L2 modulate airway inflammation and iNKT-cell-dependent airway hyperreactivity in opposing directions. Mucosal Immunol. 3(1), 81-91 (2010
-
(2010)
Mucosal Immunol
, vol.3
, Issue.1
, pp. 81-91
-
-
Akbari, O.1
Stock, P.2
Singh, A.K.3
-
68
-
-
36048978911
-
Foxp3 transcription-factordependent and-independent regulation of the regulatory T cell transcriptional signature
-
Hill JA, Feuerer M, Tash K, et al. Foxp3 transcription-factordependent and-independent regulation of the regulatory T cell transcriptional signature. Immunity 27(5), 786-800 (2007
-
(2007)
Immunity
, vol.27
, Issue.5
, pp. 786-800
-
-
Hill, J.A.1
Feuerer, M.2
Tash, K.3
-
69
-
-
84947444410
-
Clinical activity and safety from a Phase II study (FIR of MPDL3280A (anti-PDL1) in PD-L1-selected patients with non-small cell lung cancer (NSCLC)
-
Spigel DR, Chaft JE, Gettinger SN, et al. Clinical activity and safety from a Phase II study (FIR) of MPDL3280A (anti-PDL1) in PD-L1-selected patients with non-small cell lung cancer (NSCLC). ASCO Meeting Abstracts 33(SUPPL 15), 8028 (2015
-
(2015)
ASCO Meeting Abstracts
, vol.33
, Issue.SUPPL. 15
, pp. 8028
-
-
Spigel, D.R.1
Chaft, J.E.2
Gettinger, S.N.3
-
70
-
-
84959416013
-
Evaluation of PD-L1 expression in metachronous tumor samples and FDG-PET as a predictive biomarker in Ph2 study (FIR) of Atezolizumab (MPDL3280A
-
Denver CO, USA 6-9 September
-
Chaft Je CB, Akerley Wl, et al. Evaluation of PD-L1 expression in metachronous tumor samples and FDG-PET as a predictive biomarker in Ph2 study (FIR) of Atezolizumab (MPDL3280A). Presented at: 16th World Conference on Lung Cancer. Denver, CO, USA, 6-9 September 2015
-
(2015)
Presented At: 16th World Conference on Lung Cancer
-
-
Chaft Je, C.B.1
Akerley, W.L.2
-
71
-
-
84942138309
-
Efficacy, safety and predictive biomarker results from a randomized Phase II study comparing MPDL3280A vs docetaxel in 2L/3L NSCLC (POPLAR
-
Spira AI, Park K, Mazieres J, et al. Efficacy, safety and predictive biomarker results from a randomized Phase II study comparing MPDL3280A vs docetaxel in 2L/3L NSCLC (POPLAR). ASCO Meeting Abstracts 33(SUPPL 15), 8010 (2015
-
(2015)
ASCO Meeting Abstracts
, vol.33
, Issue.SUPPL. 15
, pp. 8010
-
-
Spira, A.I.1
Park, K.2
Mazieres, J.3
-
72
-
-
84930943770
-
Clinical trials of MPDL3280A (anti-PDL1 in patients (pts) with nonsmall-cell lung cancer (NSCLC)
-
Rizvi NA, Chow LQM, Dirix LY, et al. Clinical trials of MPDL3280A (anti-PDL1) in patients (pts) with nonsmall-cell lung cancer (NSCLC). ASCO Meeting Abstracts 32(SUPPL 15), TPS8123 (2014
-
(2014)
ASCO Meeting Abstracts
, vol.32
, Issue.SUPPL. 15
, pp. TPS8123
-
-
Rizvi, N.A.1
Chow, L.Q.M.2
Dirix, L.Y.3
-
73
-
-
84907651084
-
Clinical activity and biomarkers of MEDI4736, an anti-PD-L1 antibody, in patients with NSCLC
-
Brahmer JR, Rizvi NA, Lutzky J, et al. Clinical activity and biomarkers of MEDI4736, an anti-PD-L1 antibody, in patients with NSCLC. ASCO Meeting Abstracts 32(SUPPL 15), 8021 (2014
-
(2014)
ASCO Meeting Abstracts
, vol.32
, Issue.SUPPL. 15
, pp. 8021
-
-
Brahmer, J.R.1
Rizvi, N.A.2
Lutzky, J.3
-
74
-
-
84944734156
-
Safety and clinical activity of MEDI4736, an anti-programmed cell deathligand 1 (PD-L1 antibody, in patients with non-smallcell lung cancer (NSCLC)
-
Rizvi NA, Brahmer JR, Ou S-HI, et al. Safety and clinical activity of MEDI4736, an anti-programmed cell deathligand 1 (PD-L1) antibody, in patients with non-smallcell lung cancer (NSCLC). ASCO Meeting Abstracts 33(SUPPL 15), 8032 (2015
-
(2015)
ASCO Meeting Abstracts
, vol.33
, Issue.SUPPL. 15
, pp. 8032
-
-
Rizvi, N.A.1
Brahmer, J.R.2
Ou, S.-H.I.3
-
75
-
-
84908269560
-
Nivolumab (anti-PD-1; BMS-936558, ONO-4538) and ipilimumab in first-line NSCLC: Interim Phase i results
-
Antonia SJ, Gettinger SN, Chow LQM, et al. Nivolumab (anti-PD-1; BMS-936558, ONO-4538) and ipilimumab in first-line NSCLC: interim Phase I results. ASCO Meeting Abstracts 32(SUPPL 15), 8023 (2014
-
(2014)
ASCO Meeting Abstracts
, vol.32
, Issue.SUPPL. 15
, pp. 8023
-
-
Antonia, S.J.1
Gettinger, S.N.2
Chow, L.Q.M.3
-
76
-
-
84922634440
-
A phase 1 study to evaluate the safety and tolerability of MEDI4736, an anti-PD-L1 antibody, in combination with tremelimumab in patients with advanced solid tumors
-
Callahan MK, Ott PA, Odunsi K, et al. A phase 1 study to evaluate the safety and tolerability of MEDI4736, an anti-PD-L1 antibody, in combination with tremelimumab in patients with advanced solid tumors. ASCO Meeting Abstracts 32(SUPPL 15), TPS3120 (2014
-
(2014)
ASCO Meeting Abstracts
, vol.32
, Issue.SUPPL. 15
, pp. TPS3120
-
-
Callahan, M.K.1
Ott, P.A.2
Odunsi, K.3
-
77
-
-
84942138310
-
Phase 1 study of pembrolizumab (pembro; MK-3475) plus ipilimumab (IPI) as second-line therapy for advanced non-small-cell lung cancer (NSCLC): KEYNOTE-021 cohort D
-
Patnaik A, Socinski MA, Gubens MA, et al. Phase 1 study of pembrolizumab (pembro; MK-3475) plus ipilimumab (IPI) as second-line therapy for advanced non-small-cell lung cancer (NSCLC): KEYNOTE-021 cohort D. ASCO Meeting Abstracts 33(SUPPL 15), 8011 (2015
-
(2015)
ASCO Meeting Abstracts
, vol.33
, Issue.SUPPL. 15
, pp. 8011
-
-
Patnaik, A.1
Socinski, M.A.2
Gubens, M.A.3
-
78
-
-
84959416014
-
Long-Term survival, clinical activity and safety of nivolumab (anti-Pd-1; Bms-936558, Ono-4538) in patients (Pts) with advanced non-small cell lung cancer (NSCLC
-
Chicago, USA October-November 1 2014 (Poster 170
-
Gettinger Sn HL, Gandhi L, et al. Long-Term survival, clinical activity and safety of nivolumab (anti-Pd-1; Bms-936558, Ono-4538) in patients (Pts) with advanced non-small cell lung cancer (NSCLC). Presented at: Chicago Multidisciplinary Symposium in Thoracic Oncology (CMTSO) Annual Meeting. Chicago, USA, 30 October-November 1 2014 (Poster 170
-
Presented At: Chicago Multidisciplinary Symposium in Thoracic Oncology (CMTSO) Annual Meeting
, vol.30
-
-
Gettinger Sn, H.L.1
Gandhi, L.2
-
79
-
-
84907614647
-
Safety and clinical activity of MK-3475 as initial therapy in patients with advanced non-small cell lung cancer (NSCLC
-
Rizvi NA, Garon EB, Patnaik A, et al. Safety and clinical activity of MK-3475 as initial therapy in patients with advanced non-small cell lung cancer (NSCLC). ASCO Meeting Abstracts 32(SUPPL 15), 8007 (2014
-
(2014)
ASCO Meeting Abstracts
, vol.32
, Issue.SUPPL. 15
, pp. 8007
-
-
Rizvi, N.A.1
Garon, E.B.2
Patnaik, A.3
-
80
-
-
84907651085
-
Safety and response with nivolumab (anti-PD-1; BMS-936558, ONO-4538) plus erlotinib in patients (pts) with epidermal growth factor receptor mutant (EGFR MT) advanced NSCLC
-
Rizvi NA, Chow LQM, Borghaei H, et al. Safety and response with nivolumab (anti-PD-1; BMS-936558, ONO-4538) plus erlotinib in patients (pts) with epidermal growth factor receptor mutant (EGFR MT) advanced NSCLC. ASCO Meeting Abstracts 32(SUPPL 15), 8022 (2014
-
(2014)
ASCO Meeting Abstracts
, vol.32
, Issue.SUPPL. 15
, pp. 8022
-
-
Rizvi, N.A.1
Chow, L.Q.M.2
Borghaei, H.3
-
81
-
-
84947444749
-
Pembrolizumab (pembro; MK-3475) plus platinum doublet chemotherapy (PDC) as front-line therapy for advanced nonsmall cell lung cancer (NSCLC): KEYNOTE-021 Cohorts A and C
-
Papadimitrakopoulou V, Patnaik A, Borghaei H, et al. Pembrolizumab (pembro; MK-3475) plus platinum doublet chemotherapy (PDC) as front-line therapy for advanced nonsmall cell lung cancer (NSCLC): KEYNOTE-021 Cohorts A and C. ASCO Meeting Abstracts 33(SUPPL 15), 8031 (2015
-
(2015)
ASCO Meeting Abstracts
, vol.33
, Issue.SUPPL. 15
, pp. 8031
-
-
Papadimitrakopoulou, V.1
Patnaik, A.2
Borghaei, H.3
-
82
-
-
84944739668
-
Safety and efficacy of MPDL3280A (anti-PDL1 in combination with platinumbased doublet chemotherapy in patients with advanced nonsmall-cell lung cancer (NSCLC)
-
Liu SV, Powderly JD, Camidge DR, et al. Safety and efficacy of MPDL3280A (anti-PDL1) in combination with platinumbased doublet chemotherapy in patients with advanced nonsmall-cell lung cancer (NSCLC). ASCO Meeting Abstracts 33(SUPPL 15), 8030 (2015
-
(2015)
ASCO Meeting Abstracts
, vol.33
, Issue.SUPPL. 15
, pp. 8030
-
-
Liu, S.V.1
Powderly, J.D.2
Camidge, D.R.3
-
83
-
-
84908269560
-
Nivolumab (anti-PD-1; BMS-936558, ONO-4538 in combination with platinum-based doublet chemotherapy (PT-DC) in advanced non-small-cell lung cancer (NSCLC)
-
Antonia SJ, Brahmer JR, Gettinger SN, et al. Nivolumab (anti-PD-1; BMS-936558, ONO-4538) in combination with platinum-based doublet chemotherapy (PT-DC) in advanced non-small-cell lung cancer (NSCLC). ASCO Meeting Abstracts 32(SUPPL 15), 8113 (2014
-
(2014)
ASCO Meeting Abstracts
, vol.32
, Issue.SUPPL. 15
, pp. 8113
-
-
Antonia, S.J.1
Brahmer, J.R.2
Gettinger, S.N.3
-
84
-
-
84874869077
-
Antagonist antibodies to PD-1 and B7-H1 (PD-L1) in the treatment of advanced human cancer
-
Sznol M, Chen L. Antagonist antibodies to PD-1 and B7-H1 (PD-L1) in the treatment of advanced human cancer. Clin. Cancer Res. 19(5), 1021-1034 (2013
-
(2013)
Clin. Cancer Res
, vol.19
, Issue.5
, pp. 1021-1034
-
-
Sznol, M.1
Chen, L.2
-
85
-
-
84859128199
-
Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape
-
127ra137-127ra137
-
Taube JM, Anders RA, Young GD, et al. Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape. Sci. Transl. Med. 4(127), 127ra137-127ra137 (2012
-
(2012)
Sci. Transl. Med
, vol.4
, Issue.127
-
-
Taube, J.M.1
Anders, R.A.2
Young, G.D.3
-
86
-
-
77954332103
-
Early stage and locally advanced (non-metastatic) non-small-cell lung cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up
-
Crino L, Weder W, Van Meerbeeck J, Felip E. Early stage and locally advanced (non-metastatic) non-small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann. Oncol. 21(SUPPL 5), v103-v115 (2010
-
(2010)
Ann. Oncol
, vol.21
, Issue.SUPPL. 5
, pp. v103-v115
-
-
Crino, L.1
Weder, W.2
Van Meerbeeck, J.3
Felip, E.4
-
87
-
-
67650844443
-
The new lung cancer staging system
-
Detterbeck FC, Boffa DJ, Tanoue LT. The new lung cancer staging system. Chest 136(1), 260-271 (2009
-
(2009)
Chest
, vol.136
, Issue.1
, pp. 260-271
-
-
Detterbeck, F.C.1
Boffa, D.J.2
Tanoue, L.T.3
-
88
-
-
84891534246
-
Programmed death ligand-1 expression in non-small-cell lung cancer
-
Velcheti V, Schalper KA, Carvajal DE, et al. Programmed death ligand-1 expression in non-small-cell lung cancer. Lab. Invest. 94(1), 107-116 (2014
-
(2014)
Lab. Invest
, vol.94
, Issue.1
, pp. 107-116
-
-
Velcheti, V.1
Schalper, K.A.2
Carvajal, D.E.3
-
89
-
-
84894030202
-
Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies
-
Kohrt HE, Thielens A, Marabelle A, et al. Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies. Blood 123(5), 678-686 (2014
-
(2014)
Blood
, vol.123
, Issue.5
, pp. 678-686
-
-
Kohrt, H.E.1
Thielens, A.2
Marabelle, A.3
-
90
-
-
84919632874
-
OX40-And CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence
-
Buchan SL, Manzo T, Flutter B, et al. OX40-And CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence. J. Immunol. 194(1), 125-133 (2015
-
(2015)
J. Immunol
, vol.194
, Issue.1
, pp. 125-133
-
-
Buchan, S.L.1
Manzo, T.2
Flutter, B.3
-
91
-
-
84881458660
-
Tumor-infiltrating regulatory T cells inhibit endogenous cytotoxic T cell responses to lung adenocarcinoma
-
Ganesan AP, Johansson M, Ruffell B, et al. Tumor-infiltrating regulatory T cells inhibit endogenous cytotoxic T cell responses to lung adenocarcinoma. J. Immunol. 191(4), 2009-2017 (2013
-
(2013)
J. Immunol
, vol.191
, Issue.4
, pp. 2009-2017
-
-
Ganesan, A.P.1
Johansson, M.2
Ruffell, B.3
-
92
-
-
84920081022
-
Preliminary results from a phase 1/2 study of INCB024360 combined with ipilimumab (ipi) in patients (pts) with melanoma
-
Gibney GT, Hamid O, Gangadhar TC, et al. Preliminary results from a phase 1/2 study of INCB024360 combined with ipilimumab (ipi) in patients (pts) with melanoma. ASCO Meeting Abstracts 32(SUPPL 15), 3010 (2014
-
(2014)
ASCO Meeting Abstracts
, vol.32
, Issue.SUPPL. 15
, pp. 3010
-
-
Gibney, G.T.1
Hamid, O.2
Gangadhar, T.C.3
-
93
-
-
85019348584
-
A firstin-human study of pegylated recombinant human IL-10 (AM0010) daily administered for four months in selected advanced solid tumors
-
Bauer TM, Papadopoulos KP, Autio KA, et al. A firstin-human study of pegylated recombinant human IL-10 (AM0010), daily administered for four months in selected advanced solid tumors. ASCO Meeting Abstracts 32(SUPPL 15), TPS3126 (2014
-
(2014)
ASCO Meeting Abstracts
, vol.32
, Issue.SUPPL. 15
, pp. TPS3126
-
-
Bauer, T.M.1
Papadopoulos, K.P.2
Autio, K.A.3
-
94
-
-
34548240159
-
Tremelimumab (CP-675, 206), a cytotoxic T lymphocyte associated antigen 4 blocking monoclonal antibody in clinical development for patients with cancer
-
Ribas A, Hanson DC, Noe DA, et al. Tremelimumab (CP-675, 206), a cytotoxic T lymphocyte associated antigen 4 blocking monoclonal antibody in clinical development for patients with cancer. Oncologist 12(7), 873-883 (2007
-
(2007)
Oncologist
, vol.12
, Issue.7
, pp. 873-883
-
-
Ribas, A.1
Hanson, D.C.2
Noe, D.A.3
-
95
-
-
84879759020
-
Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
-
Hamid O, Robert C, Daud A, et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N. Engl. J.Med. 369(2), 134-144 (2013
-
(2013)
N. Engl. J.Med
, vol.369
, Issue.2
, pp. 134-144
-
-
Hamid, O.1
Robert, C.2
Daud, A.3
-
96
-
-
84928760665
-
Anti-programmed cell death protein-1/ligand-1 therapy in different cancers
-
Homet Moreno B, Ribas A. Anti-programmed cell death protein-1/ligand-1 therapy in different cancers. Br. J. Cancer 112(9), 1421-1427 (2015
-
(2015)
Br. J. Cancer
, vol.112
, Issue.9
, pp. 1421-1427
-
-
Homet Moreno, B.1
Ribas, A.2
-
97
-
-
84924809260
-
Nivolumab in NSCLC: Latest evidence and clinical potential
-
Sundar R, Cho BC, Brahmer JR, Soo RA. Nivolumab in NSCLC: latest evidence and clinical potential. Ther. Adv. Med. Oncol. 7(2), 85-96 (2015
-
(2015)
Ther. Adv. Med. Oncol
, vol.7
, Issue.2
, pp. 85-96
-
-
Sundar, R.1
Cho, B.C.2
Brahmer, J.R.3
Soo, R.A.4
-
98
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer JR, Tykodi SS, Chow LQM, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N. Engl. J.Med. 366(26), 2455-2465 (2012
-
(2012)
N. Engl. J.Med
, vol.366
, Issue.26
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.M.3
-
99
-
-
84890933630
-
Update on immune checkpoint inhibitors in lung cancer
-
Creelan BC. Update on immune checkpoint inhibitors in lung cancer. Cancer Control 21(1), 80-89 (2014
-
(2014)
Cancer Control
, vol.21
, Issue.1
, pp. 80-89
-
-
Creelan, B.C.1
-
100
-
-
84655170271
-
The European Medicines Agency review of ipilimumab (Yervoy) for the treatment of advanced (unresectable or metastatic) melanoma in adults who have received prior therapy: Summary of the scientific assessment of the committee for medicinal products for human use
-
Hanaizi Z, Van Zwieten-Boot B, Calvo G, et al. The European Medicines Agency review of ipilimumab (Yervoy) for the treatment of advanced (unresectable or metastatic) melanoma in adults who have received prior therapy: summary of the scientific assessment of the Committee for Medicinal Products for Human Use. Eur. J. Cancer 48(2), 237-242 (2012
-
(2012)
Eur. J. Cancer
, vol.48
, Issue.2
, pp. 237-242
-
-
Hanaizi, Z.1
Van Zwieten-Boot, B.2
Calvo, G.3
-
102
-
-
85019371131
-
2012) Pd-1 and Ctla-4 mediated inhibitory signaling for T cell exhaustion during chronic viral infections
-
Li C XX, Wang H, Wei B (2012) Pd-1 and Ctla-4 mediated inhibitory signaling for T cell exhaustion during chronic viral infections. J.Clin. Cell. Immunol. doi: 10.4172/2155-9899.S12-010 (2012
-
(2012)
J.Clin. Cell. Immunol
-
-
Li, C.X.X.1
Wang, H.2
Wei, B.3
|