메뉴 건너뛰기




Volumn 18, Issue 6, 1998, Pages 3140-3148

Mechanism responsible for T-cell antigen receptor- and CD28- or interleukin 1 (IL-1) receptor-initiated regulation of IL-2 gene expression by NF-κB

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CYCLOSPORIN A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 2; T LYMPHOCYTE RECEPTOR;

EID: 0031842613     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/mcb.18.6.3140     Document Type: Article
Times cited : (61)

References (37)
  • 1
    • 0023664030 scopus 로고
    • Transmembrane signalling during IL-1-dependent T cell activation: Interaction of signal 1-and signal 2-type mediators with the phosphoinositide-dependent signal transduction mechanism
    • Abraham, R. T., S. Ho, T. Barna, and D. J. McKean. 1987. Transmembrane signalling during IL-1-dependent T cell activation: interaction of signal 1-and signal 2-type mediators with the phosphoinositide-dependent signal transduction mechanism. J. Biol. Chem. 262:2719-2729.
    • (1987) J. Biol. Chem. , vol.262 , pp. 2719-2729
    • Abraham, R.T.1    Ho, S.2    Barna, T.3    McKean, D.J.4
  • 2
    • 0029874138 scopus 로고    scopus 로고
    • The NF-κB and IκB proteins: New discoveries and insights
    • Baldwin, A. S. 1996. The NF-κB and IκB proteins: new discoveries and insights. Annu. Rev. Immunol. 14:649-681.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 649-681
    • Baldwin, A.S.1
  • 4
    • 0025477382 scopus 로고
    • Cyclosporin A inhibits induction of IL-2 receptor alpha chain expression by affecting activation of NF-κB-like factor(s) in cultured human T lymphocytes
    • Brini, A. T., A. Harel-Bellan, and W. L. Farrar. 1990. Cyclosporin A inhibits induction of IL-2 receptor alpha chain expression by affecting activation of NF-κB-like factor(s) in cultured human T lymphocytes. Eur. Cytokine Netw. 1:131-139.
    • (1990) Eur. Cytokine Netw. , vol.1 , pp. 131-139
    • Brini, A.T.1    Harel-Bellan, A.2    Farrar, W.L.3
  • 5
    • 0029146930 scopus 로고
    • Signal-induced site-specific phosphorylation targets IκB-α to the ubiquitin-A proteasome pathway
    • Chen, A., J. Hagler, V. J. Palombella, F. Melandri, D. Scherer, D. Ballard, and T. Maniatis. 1995. Signal-induced site-specific phosphorylation targets IκB-α to the ubiquitin-A proteasome pathway. Genes Dev. 9:1586-1597.
    • (1995) Genes Dev. , vol.9 , pp. 1586-1597
    • Chen, A.1    Hagler, J.2    Palombella, V.J.3    Melandri, F.4    Scherer, D.5    Ballard, D.6    Maniatis, T.7
  • 6
    • 0029808167 scopus 로고    scopus 로고
    • Basal phosphorylation of the PEST domain in IκBβ regulates its functional interaction with the c-rel proto-oncogene product
    • Chu, Z.-L., T. A. McKinsey, L. Liu, X. Qi, and D. W. Ballard. 1996. Basal phosphorylation of the PEST domain in IκBβ regulates its functional interaction with the c-rel proto-oncogene product. Mol. Cell. Biol. 16:5974-5984.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5974-5984
    • Chu, Z.-L.1    McKinsey, T.A.2    Liu, L.3    Qi, X.4    Ballard, D.W.5
  • 7
    • 0029670083 scopus 로고    scopus 로고
    • Mapping of the inducible IκB phosphorylation sites that signal its ubiquitination and degradation
    • DiDonato, J., F. Mercurio, C. Rosette, J. Wu-Li, H. Suyang, S. Ghosh, and M. Karin. 1996. Mapping of the inducible IκB phosphorylation sites that signal its ubiquitination and degradation. Mol. Cell. Biol. 16:1295-1304.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1295-1304
    • DiDonato, J.1    Mercurio, F.2    Rosette, C.3    Wu-Li, J.4    Suyang, H.5    Ghosh, S.6    Karin, M.7
  • 8
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam, J. D., R. M. Liebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475-1489.
    • (1983) Nucleic Acids Res. , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Liebovitz, R.M.2    Roeder, R.G.3
  • 9
    • 0028170255 scopus 로고
    • Differential interactions of Rel-NF-kappa B complexes with I kappa B alpha determine pools of constitutive and inducible NF-kappa B activity
    • Dobrzanski, P., R. P. Ryseck, and R. Bravo. 1994. Differential interactions of Rel-NF-kappa B complexes with I kappa B alpha determine pools of constitutive and inducible NF-kappa B activity. EMBO J. 13:4608-4609.
    • (1994) EMBO J. , vol.13 , pp. 4608-4609
    • Dobrzanski, P.1    Ryseck, R.P.2    Bravo, R.3
  • 10
    • 0026061865 scopus 로고
    • Regulation of the interleukin-2 gene enhancer activity by the T cell accessory molecule CD28
    • Fraser, J. D., B. A. Irving, G. R. Crabtree, and A. Weiss. 1991. Regulation of the interleukin-2 gene enhancer activity by the T cell accessory molecule CD28. Science 251:313-316.
    • (1991) Science , vol.251 , pp. 313-316
    • Fraser, J.D.1    Irving, B.A.2    Crabtree, G.R.3    Weiss, A.4
  • 11
    • 0027410856 scopus 로고
    • The interleukin 2 CD29-responsive complex contains at least three members of the NF-κB family: c-Rel, p50, and p65
    • Ghosh, P., T.-H. Tan, N. R. Rice, A. Sica, and H. A. Young. 1993. The interleukin 2 CD29-responsive complex contains at least three members of the NF-κB family: c-Rel, p50, and p65. Proc. Natl. Acad. Sci. USA 90:1696-1700.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1696-1700
    • Ghosh, P.1    Tan, T.-H.2    Rice, N.R.3    Sica, A.4    Young, H.A.5
  • 12
    • 0030942258 scopus 로고    scopus 로고
    • Mechanism for biphasic RelA-NF-κB1 nuclear translocation in tumor necrosis factor α-stimulated hepatocytes
    • Han, Y., and A. R. Brasier. 1997. Mechanism for biphasic RelA-NF-κB1 nuclear translocation in tumor necrosis factor α-stimulated hepatocytes. J. Biol. Chem. 272:9825-9832.
    • (1997) J. Biol. Chem. , vol.272 , pp. 9825-9832
    • Han, Y.1    Brasier, A.R.2
  • 13
    • 0029977948 scopus 로고    scopus 로고
    • CD28 mediates a potent costimulatory signal for rapid degradation of IκBβ which is associated with accelerated activation of various NF-κB/Rel heterodimers
    • Harhaj, E. W., S. B. Maggirwar, L. Good, and S.-C. Sun. 1996. CD28 mediates a potent costimulatory signal for rapid degradation of IκBβ which is associated with accelerated activation of various NF-κB/Rel heterodimers. Mol. Cell. Biol. 16:6736-6743.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 6736-6743
    • Harhaj, E.W.1    Maggirwar, S.B.2    Good, L.3    Sun, S.-C.4
  • 14
    • 0024584166 scopus 로고
    • Kappa B-spccitic DNA binding proteins: Role in the regulation of human interleukin-2 gene expression
    • Hoyos, B., D. W. Ballard, E. Bohnlein, M. Siekevitz, and W. C. Greene. 1989. Kappa B-spccitic DNA binding proteins: role in the regulation of human interleukin-2 gene expression. Science 244:457-460.
    • (1989) Science , vol.244 , pp. 457-460
    • Hoyos, B.1    Ballard, D.W.2    Bohnlein, E.3    Siekevitz, M.4    Greene, W.C.5
  • 15
    • 0029666281 scopus 로고    scopus 로고
    • A sustained reduction in IκB-α may contribute to persistent NF-κB activation in human endothelial cells
    • Johnson, D. R., I. Douglas, A. Jahnke, S. Ghosh, and J. S. Pober. 1996. A sustained reduction in IκB-α may contribute to persistent NF-κB activation in human endothelial cells. J. Biol. Chem. 271:16317-16322.
    • (1996) J. Biol. Chem. , vol.271 , pp. 16317-16322
    • Johnson, D.R.1    Douglas, I.2    Jahnke, A.3    Ghosh, S.4    Pober, J.S.5
  • 16
    • 0023637951 scopus 로고
    • T-cell proliferation involving the CD28 pathway is associated with cyclosporin-resistant interleukin 2 gene expression
    • June, C. H., J. A. Ledbetter, M. M. Gillespie, T. Lindsten, and C. B. Thompson. 1987. T-cell proliferation involving the CD28 pathway is associated with cyclosporin-resistant interleukin 2 gene expression. Mol. Cell. Biol. 7:4472-4481.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 4472-4481
    • June, C.H.1    Ledbetter, J.A.2    Gillespie, M.M.3    Lindsten, T.4    Thompson, C.B.5
  • 17
    • 0024828378 scopus 로고
    • T lymphocyte activation through the C28 (sic) pathway is insensitive to inhibition by the immunosuppressive drug FK-506
    • Kay, J. E., and C. R. Benzie. 1989/1990. T lymphocyte activation through the C28 (sic) pathway is insensitive to inhibition by the immunosuppressive drug FK-506. Immunol. Lett. 23:155-160.
    • (1989) Immunol. Lett. , vol.23 , pp. 155-160
    • Kay, J.E.1    Benzie, C.R.2
  • 18
    • 0029150389 scopus 로고
    • Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression
    • Köntgen, F., R. J. Grumont, A. Strasser, D. Metcalf, R. Li, D. Tarlington, and S. Gerondakis. 1995. Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression. Genes Dev. 9:1965-1977.
    • (1995) Genes Dev. , vol.9 , pp. 1965-1977
    • Köntgen, F.1    Grumont, R.J.2    Strasser, A.3    Metcalf, D.4    Li, R.5    Tarlington, D.6    Gerondakis, S.7
  • 19
    • 0027970168 scopus 로고
    • CD28 signaling causes a sustained down-regulation of IκBα which can be prevented by the immunosuppressant rapamycin
    • Lai, J. H., and T. H. Tan. 1994. CD28 signaling causes a sustained down-regulation of IκBα which can be prevented by the immunosuppressant rapamycin. J. Biol. Chem. 269:30077-30080.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30077-30080
    • Lai, J.H.1    Tan, T.H.2
  • 20
    • 0027453548 scopus 로고
    • Promoter analysis of the gene encoding the IκB-α/MAD3 inhibitor of NF-κB: Positive regulation by members of the rel/NFκB family
    • Le Bail, O., R. Schmidt-Ullrich, and A. Israel. 1993. Promoter analysis of the gene encoding the IκB-α/MAD3 inhibitor of NF-κB: positive regulation by members of the rel/NFκB family. EMBO J. 12:5043-5049.
    • (1993) EMBO J. , vol.12 , pp. 5043-5049
    • Le Bail, O.1    Schmidt-Ullrich, R.2    Israel, A.3
  • 21
    • 0028176488 scopus 로고
    • Cyclosporin A sensitivity of the NF-kappa B site of the IL2R alpha promoter in untransformed murine T cells
    • McCaffrey, P. G., P. K. Kim, V. E. Valge-Archer, R. Sen, and A. Rao. 1994. Cyclosporin A sensitivity of the NF-kappa B site of the IL2R alpha promoter in untransformed murine T cells. Nucleic Acids Res. 22:2134-2142.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 2134-2142
    • McCaffrey, P.G.1    Kim, P.K.2    Valge-Archer, V.E.3    Sen, R.4    Rao, A.5
  • 23
    • 0027969303 scopus 로고
    • Ligand-induced desensitizalion of inlerlcukin 1 receptor-initiated intracellular signaling events in T helper lymphocytes
    • McKean, D. J., C. Huntoon, and M. Bell. 1994. Ligand-induced desensitizalion of inlerlcukin 1 receptor-initiated intracellular signaling events in T helper lymphocytes. J. Exp. Med. 180:1321-1328.
    • (1994) J. Exp. Med. , vol.180 , pp. 1321-1328
    • McKean, D.J.1    Huntoon, C.2    Bell, M.3
  • 24
    • 0027243576 scopus 로고
    • p105 and p98 precursor proteins play an active role in NF-κB-mediated signal transduction
    • Mercurio, F., J. A. DiDonato, C. Rosette, and M. Karin. 1993. p105 and p98 precursor proteins play an active role in NF-κB-mediated signal transduction. Genes Dev. 7:705-718.
    • (1993) Genes Dev. , vol.7 , pp. 705-718
    • Mercurio, F.1    DiDonato, J.A.2    Rosette, C.3    Karin, M.4
  • 25
    • 0025599439 scopus 로고
    • NF-kappa B: A family of inducible and differentially expressed enhancer-binding proteins in human T cells
    • Molitor, J. A., W. H. Walker, S. Doerre, D. W. Ballard, and W. C. Greene. 1990. NF-kappa B: a family of inducible and differentially expressed enhancer-binding proteins in human T cells. Proc. Natl. Acad. Sci. USA 87: 10028-10032.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 10028-10032
    • Molitor, J.A.1    Walker, W.H.2    Doerre, S.3    Ballard, D.W.4    Greene, W.C.5
  • 26
    • 0028898457 scopus 로고
    • Biphasic control of nuclear factor-kappa B activation by the T cell receptor complex: Role of tumor necrosis factor alpha
    • Pimentel-Muinos, F. X., J. Mazana, and M. Fresno. 1995. Biphasic control of nuclear factor-kappa B activation by the T cell receptor complex: role of tumor necrosis factor alpha. Eur. J. Immunol. 25:179-186.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 179-186
    • Pimentel-Muinos, F.X.1    Mazana, J.2    Fresno, M.3
  • 27
    • 0030176384 scopus 로고    scopus 로고
    • Upstream-downstream: CD28 cosignaling pathways and T cell function
    • Rudd, C. E. 1996. Upstream-downstream: CD28 cosignaling pathways and T cell function. Immunity 4:527-534.
    • (1996) Immunity , vol.4 , pp. 527-534
    • Rudd, C.E.1
  • 28
    • 0026328031 scopus 로고
    • Activation of transcription factor NF kappa B in Jurkat cells is inhibited selectively by FK 506 in a signal-dependent manner
    • Su, M. S., and A. Semerjian. 1991. Activation of transcription factor NF kappa B in Jurkat cells is inhibited selectively by FK 506 in a signal-dependent manner. Transplant. Proc. 23:2912-2915.
    • (1991) Transplant. Proc. , vol.23 , pp. 2912-2915
    • Su, M.S.1    Semerjian, A.2
  • 29
    • 0029814276 scopus 로고    scopus 로고
    • Role of unphosphorylated, newly synthesized IκBβ in persistent activation of NF-κB
    • Suyang, H., R. Phillips, I. Douglas, and S. Ghosh. 1996. Role of unphosphorylated, newly synthesized IκBβ in persistent activation of NF-κB. Mol. Cell. Biol. 16:5444-5449.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5444-5449
    • Suyang, H.1    Phillips, R.2    Douglas, I.3    Ghosh, S.4
  • 30
    • 0028986194 scopus 로고
    • IκB-β regulates the persistent response in a biphasic activation of NF-κB
    • Thompson, J. E., R. J. Phillips, H. Erdjument-Bromage, P. Tempst, and S. Ghosh. 1995. IκB-β regulates the persistent response in a biphasic activation of NF-κB. Cell 80:573-582.
    • (1995) Cell , vol.80 , pp. 573-582
    • Thompson, J.E.1    Phillips, R.J.2    Erdjument-Bromage, H.3    Tempst, P.4    Ghosh, S.5
  • 31
    • 0028978032 scopus 로고
    • Phosphorylation of human IκB-α on serines 32 and 36 controls IκB-α proteolysis and NF-κB activation in response to diverse stimuli
    • Traenckner, E. B., H. L. Pahl, T. Henkel, K. N. Schmidt, S. Wilk, and P. A. Baeuerle. 1995. Phosphorylation of human IκB-α on serines 32 and 36 controls IκB-α proteolysis and NF-κB activation in response to diverse stimuli. EMBO J. 14:2876-2883.
    • (1995) EMBO J. , vol.14 , pp. 2876-2883
    • Traenckner, E.B.1    Pahl, H.L.2    Henkel, T.3    Schmidt, K.N.4    Wilk, S.5    Baeuerle, P.A.6
  • 32
    • 0019402464 scopus 로고
    • Monoclonal anti-human T lymphocyte antibodies: Enumeration and characterization of T cell subsets
    • Van Wauwe, J., and J. G. Goossens. 1981. Monoclonal anti-human T lymphocyte antibodies: enumeration and characterization of T cell subsets. Immunology 42:157-164.
    • (1981) Immunology , vol.42 , pp. 157-164
    • Van Wauwe, J.1    Goossens, J.G.2
  • 33
    • 0028907128 scopus 로고
    • FK506 inhibits antigen receptor-mediated induction of c-Rel in B and T lymphoid cells
    • Venkataraman, L., S. J. Burakoff, and R. Sen. 1995. FK506 inhibits antigen receptor-mediated induction of c-Rel in B and T lymphoid cells. J. Exp. Med. 181:1091-1099.
    • (1995) J. Exp. Med. , vol.181 , pp. 1091-1099
    • Venkataraman, L.1    Burakoff, S.J.2    Sen, R.3
  • 34
    • 0026332710 scopus 로고
    • Activation of interleukin-2 gene transcription via the T-cell surface molecule CD28 is mediated through an NF-κB-like response element
    • Verweij, C. L., M. Geerts, and L. A. Aarden. 1991. Activation of interleukin-2 gene transcription via the T-cell surface molecule CD28 is mediated through an NF-κB-like response element. J. Biol. Chem. 266:14179-14182.
    • (1991) J. Biol. Chem. , vol.266 , pp. 14179-14182
    • Verweij, C.L.1    Geerts, M.2    Aarden, L.A.3
  • 35
    • 0030907779 scopus 로고    scopus 로고
    • c-Rel is a target of pentoxifylline-mediated inhibition of T-lymphocyte activation
    • Wang, W., W. F. Tam, C. C. W. Hughes, S. Rath, and R. Sen. 1997. c-Rel is a target of pentoxifylline-mediated inhibition of T-lymphocyte activation. Immunity 6:165-174.
    • (1997) Immunity , vol.6 , pp. 165-174
    • Wang, W.1    Tam, W.F.2    Hughes, C.C.W.3    Rath, S.4    Sen, R.5
  • 37
    • 0028068807 scopus 로고
    • Positive and negative regulation of IL-2 gene expression: Role of multiple regulatory sites
    • Zhang, L., and G. J. Nabel. 1994. Positive and negative regulation of IL-2 gene expression: role of multiple regulatory sites. Cytokine 6:221-228.
    • (1994) Cytokine , vol.6 , pp. 221-228
    • Zhang, L.1    Nabel, G.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.