-
1
-
-
0023664030
-
Transmembrane signalling during IL-1-dependent T cell activation: Interaction of signal 1-and signal 2-type mediators with the phosphoinositide-dependent signal transduction mechanism
-
Abraham, R. T., S. Ho, T. Barna, and D. J. McKean. 1987. Transmembrane signalling during IL-1-dependent T cell activation: interaction of signal 1-and signal 2-type mediators with the phosphoinositide-dependent signal transduction mechanism. J. Biol. Chem. 262:2719-2729.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 2719-2729
-
-
Abraham, R.T.1
Ho, S.2
Barna, T.3
McKean, D.J.4
-
2
-
-
0029874138
-
The NF-κB and IκB proteins: New discoveries and insights
-
Baldwin, A. S. 1996. The NF-κB and IκB proteins: new discoveries and insights. Annu. Rev. Immunol. 14:649-681.
-
(1996)
Annu. Rev. Immunol.
, vol.14
, pp. 649-681
-
-
Baldwin, A.S.1
-
4
-
-
0025477382
-
Cyclosporin A inhibits induction of IL-2 receptor alpha chain expression by affecting activation of NF-κB-like factor(s) in cultured human T lymphocytes
-
Brini, A. T., A. Harel-Bellan, and W. L. Farrar. 1990. Cyclosporin A inhibits induction of IL-2 receptor alpha chain expression by affecting activation of NF-κB-like factor(s) in cultured human T lymphocytes. Eur. Cytokine Netw. 1:131-139.
-
(1990)
Eur. Cytokine Netw.
, vol.1
, pp. 131-139
-
-
Brini, A.T.1
Harel-Bellan, A.2
Farrar, W.L.3
-
5
-
-
0029146930
-
Signal-induced site-specific phosphorylation targets IκB-α to the ubiquitin-A proteasome pathway
-
Chen, A., J. Hagler, V. J. Palombella, F. Melandri, D. Scherer, D. Ballard, and T. Maniatis. 1995. Signal-induced site-specific phosphorylation targets IκB-α to the ubiquitin-A proteasome pathway. Genes Dev. 9:1586-1597.
-
(1995)
Genes Dev.
, vol.9
, pp. 1586-1597
-
-
Chen, A.1
Hagler, J.2
Palombella, V.J.3
Melandri, F.4
Scherer, D.5
Ballard, D.6
Maniatis, T.7
-
6
-
-
0029808167
-
Basal phosphorylation of the PEST domain in IκBβ regulates its functional interaction with the c-rel proto-oncogene product
-
Chu, Z.-L., T. A. McKinsey, L. Liu, X. Qi, and D. W. Ballard. 1996. Basal phosphorylation of the PEST domain in IκBβ regulates its functional interaction with the c-rel proto-oncogene product. Mol. Cell. Biol. 16:5974-5984.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 5974-5984
-
-
Chu, Z.-L.1
McKinsey, T.A.2
Liu, L.3
Qi, X.4
Ballard, D.W.5
-
7
-
-
0029670083
-
Mapping of the inducible IκB phosphorylation sites that signal its ubiquitination and degradation
-
DiDonato, J., F. Mercurio, C. Rosette, J. Wu-Li, H. Suyang, S. Ghosh, and M. Karin. 1996. Mapping of the inducible IκB phosphorylation sites that signal its ubiquitination and degradation. Mol. Cell. Biol. 16:1295-1304.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1295-1304
-
-
DiDonato, J.1
Mercurio, F.2
Rosette, C.3
Wu-Li, J.4
Suyang, H.5
Ghosh, S.6
Karin, M.7
-
8
-
-
0021100690
-
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
-
Dignam, J. D., R. M. Liebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475-1489.
-
(1983)
Nucleic Acids Res.
, vol.11
, pp. 1475-1489
-
-
Dignam, J.D.1
Liebovitz, R.M.2
Roeder, R.G.3
-
9
-
-
0028170255
-
Differential interactions of Rel-NF-kappa B complexes with I kappa B alpha determine pools of constitutive and inducible NF-kappa B activity
-
Dobrzanski, P., R. P. Ryseck, and R. Bravo. 1994. Differential interactions of Rel-NF-kappa B complexes with I kappa B alpha determine pools of constitutive and inducible NF-kappa B activity. EMBO J. 13:4608-4609.
-
(1994)
EMBO J.
, vol.13
, pp. 4608-4609
-
-
Dobrzanski, P.1
Ryseck, R.P.2
Bravo, R.3
-
10
-
-
0026061865
-
Regulation of the interleukin-2 gene enhancer activity by the T cell accessory molecule CD28
-
Fraser, J. D., B. A. Irving, G. R. Crabtree, and A. Weiss. 1991. Regulation of the interleukin-2 gene enhancer activity by the T cell accessory molecule CD28. Science 251:313-316.
-
(1991)
Science
, vol.251
, pp. 313-316
-
-
Fraser, J.D.1
Irving, B.A.2
Crabtree, G.R.3
Weiss, A.4
-
11
-
-
0027410856
-
The interleukin 2 CD29-responsive complex contains at least three members of the NF-κB family: c-Rel, p50, and p65
-
Ghosh, P., T.-H. Tan, N. R. Rice, A. Sica, and H. A. Young. 1993. The interleukin 2 CD29-responsive complex contains at least three members of the NF-κB family: c-Rel, p50, and p65. Proc. Natl. Acad. Sci. USA 90:1696-1700.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 1696-1700
-
-
Ghosh, P.1
Tan, T.-H.2
Rice, N.R.3
Sica, A.4
Young, H.A.5
-
12
-
-
0030942258
-
Mechanism for biphasic RelA-NF-κB1 nuclear translocation in tumor necrosis factor α-stimulated hepatocytes
-
Han, Y., and A. R. Brasier. 1997. Mechanism for biphasic RelA-NF-κB1 nuclear translocation in tumor necrosis factor α-stimulated hepatocytes. J. Biol. Chem. 272:9825-9832.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 9825-9832
-
-
Han, Y.1
Brasier, A.R.2
-
13
-
-
0029977948
-
CD28 mediates a potent costimulatory signal for rapid degradation of IκBβ which is associated with accelerated activation of various NF-κB/Rel heterodimers
-
Harhaj, E. W., S. B. Maggirwar, L. Good, and S.-C. Sun. 1996. CD28 mediates a potent costimulatory signal for rapid degradation of IκBβ which is associated with accelerated activation of various NF-κB/Rel heterodimers. Mol. Cell. Biol. 16:6736-6743.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 6736-6743
-
-
Harhaj, E.W.1
Maggirwar, S.B.2
Good, L.3
Sun, S.-C.4
-
14
-
-
0024584166
-
Kappa B-spccitic DNA binding proteins: Role in the regulation of human interleukin-2 gene expression
-
Hoyos, B., D. W. Ballard, E. Bohnlein, M. Siekevitz, and W. C. Greene. 1989. Kappa B-spccitic DNA binding proteins: role in the regulation of human interleukin-2 gene expression. Science 244:457-460.
-
(1989)
Science
, vol.244
, pp. 457-460
-
-
Hoyos, B.1
Ballard, D.W.2
Bohnlein, E.3
Siekevitz, M.4
Greene, W.C.5
-
15
-
-
0029666281
-
A sustained reduction in IκB-α may contribute to persistent NF-κB activation in human endothelial cells
-
Johnson, D. R., I. Douglas, A. Jahnke, S. Ghosh, and J. S. Pober. 1996. A sustained reduction in IκB-α may contribute to persistent NF-κB activation in human endothelial cells. J. Biol. Chem. 271:16317-16322.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 16317-16322
-
-
Johnson, D.R.1
Douglas, I.2
Jahnke, A.3
Ghosh, S.4
Pober, J.S.5
-
16
-
-
0023637951
-
T-cell proliferation involving the CD28 pathway is associated with cyclosporin-resistant interleukin 2 gene expression
-
June, C. H., J. A. Ledbetter, M. M. Gillespie, T. Lindsten, and C. B. Thompson. 1987. T-cell proliferation involving the CD28 pathway is associated with cyclosporin-resistant interleukin 2 gene expression. Mol. Cell. Biol. 7:4472-4481.
-
(1987)
Mol. Cell. Biol.
, vol.7
, pp. 4472-4481
-
-
June, C.H.1
Ledbetter, J.A.2
Gillespie, M.M.3
Lindsten, T.4
Thompson, C.B.5
-
17
-
-
0024828378
-
T lymphocyte activation through the C28 (sic) pathway is insensitive to inhibition by the immunosuppressive drug FK-506
-
Kay, J. E., and C. R. Benzie. 1989/1990. T lymphocyte activation through the C28 (sic) pathway is insensitive to inhibition by the immunosuppressive drug FK-506. Immunol. Lett. 23:155-160.
-
(1989)
Immunol. Lett.
, vol.23
, pp. 155-160
-
-
Kay, J.E.1
Benzie, C.R.2
-
18
-
-
0029150389
-
Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression
-
Köntgen, F., R. J. Grumont, A. Strasser, D. Metcalf, R. Li, D. Tarlington, and S. Gerondakis. 1995. Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression. Genes Dev. 9:1965-1977.
-
(1995)
Genes Dev.
, vol.9
, pp. 1965-1977
-
-
Köntgen, F.1
Grumont, R.J.2
Strasser, A.3
Metcalf, D.4
Li, R.5
Tarlington, D.6
Gerondakis, S.7
-
19
-
-
0027970168
-
CD28 signaling causes a sustained down-regulation of IκBα which can be prevented by the immunosuppressant rapamycin
-
Lai, J. H., and T. H. Tan. 1994. CD28 signaling causes a sustained down-regulation of IκBα which can be prevented by the immunosuppressant rapamycin. J. Biol. Chem. 269:30077-30080.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 30077-30080
-
-
Lai, J.H.1
Tan, T.H.2
-
20
-
-
0027453548
-
Promoter analysis of the gene encoding the IκB-α/MAD3 inhibitor of NF-κB: Positive regulation by members of the rel/NFκB family
-
Le Bail, O., R. Schmidt-Ullrich, and A. Israel. 1993. Promoter analysis of the gene encoding the IκB-α/MAD3 inhibitor of NF-κB: positive regulation by members of the rel/NFκB family. EMBO J. 12:5043-5049.
-
(1993)
EMBO J.
, vol.12
, pp. 5043-5049
-
-
Le Bail, O.1
Schmidt-Ullrich, R.2
Israel, A.3
-
21
-
-
0028176488
-
Cyclosporin A sensitivity of the NF-kappa B site of the IL2R alpha promoter in untransformed murine T cells
-
McCaffrey, P. G., P. K. Kim, V. E. Valge-Archer, R. Sen, and A. Rao. 1994. Cyclosporin A sensitivity of the NF-kappa B site of the IL2R alpha promoter in untransformed murine T cells. Nucleic Acids Res. 22:2134-2142.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 2134-2142
-
-
McCaffrey, P.G.1
Kim, P.K.2
Valge-Archer, V.E.3
Sen, R.4
Rao, A.5
-
22
-
-
0028797947
-
IL-1 receptor and TCR signals synergize to activate NF-κB-mediated gene transcription
-
McKean, D. J., M. Bell, C. Huntoon, S. Rastogi, M. Van Norstrand, R. Podzorski, A. Nilson, and C. Paya. 1995. IL-1 receptor and TCR signals synergize to activate NF-κB-mediated gene transcription. Int. Immunol. 7:9-20.
-
(1995)
Int. Immunol.
, vol.7
, pp. 9-20
-
-
McKean, D.J.1
Bell, M.2
Huntoon, C.3
Rastogi, S.4
Van Norstrand, M.5
Podzorski, R.6
Nilson, A.7
Paya, C.8
-
23
-
-
0027969303
-
Ligand-induced desensitizalion of inlerlcukin 1 receptor-initiated intracellular signaling events in T helper lymphocytes
-
McKean, D. J., C. Huntoon, and M. Bell. 1994. Ligand-induced desensitizalion of inlerlcukin 1 receptor-initiated intracellular signaling events in T helper lymphocytes. J. Exp. Med. 180:1321-1328.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1321-1328
-
-
McKean, D.J.1
Huntoon, C.2
Bell, M.3
-
24
-
-
0027243576
-
p105 and p98 precursor proteins play an active role in NF-κB-mediated signal transduction
-
Mercurio, F., J. A. DiDonato, C. Rosette, and M. Karin. 1993. p105 and p98 precursor proteins play an active role in NF-κB-mediated signal transduction. Genes Dev. 7:705-718.
-
(1993)
Genes Dev.
, vol.7
, pp. 705-718
-
-
Mercurio, F.1
DiDonato, J.A.2
Rosette, C.3
Karin, M.4
-
25
-
-
0025599439
-
NF-kappa B: A family of inducible and differentially expressed enhancer-binding proteins in human T cells
-
Molitor, J. A., W. H. Walker, S. Doerre, D. W. Ballard, and W. C. Greene. 1990. NF-kappa B: a family of inducible and differentially expressed enhancer-binding proteins in human T cells. Proc. Natl. Acad. Sci. USA 87: 10028-10032.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 10028-10032
-
-
Molitor, J.A.1
Walker, W.H.2
Doerre, S.3
Ballard, D.W.4
Greene, W.C.5
-
26
-
-
0028898457
-
Biphasic control of nuclear factor-kappa B activation by the T cell receptor complex: Role of tumor necrosis factor alpha
-
Pimentel-Muinos, F. X., J. Mazana, and M. Fresno. 1995. Biphasic control of nuclear factor-kappa B activation by the T cell receptor complex: role of tumor necrosis factor alpha. Eur. J. Immunol. 25:179-186.
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 179-186
-
-
Pimentel-Muinos, F.X.1
Mazana, J.2
Fresno, M.3
-
27
-
-
0030176384
-
Upstream-downstream: CD28 cosignaling pathways and T cell function
-
Rudd, C. E. 1996. Upstream-downstream: CD28 cosignaling pathways and T cell function. Immunity 4:527-534.
-
(1996)
Immunity
, vol.4
, pp. 527-534
-
-
Rudd, C.E.1
-
28
-
-
0026328031
-
Activation of transcription factor NF kappa B in Jurkat cells is inhibited selectively by FK 506 in a signal-dependent manner
-
Su, M. S., and A. Semerjian. 1991. Activation of transcription factor NF kappa B in Jurkat cells is inhibited selectively by FK 506 in a signal-dependent manner. Transplant. Proc. 23:2912-2915.
-
(1991)
Transplant. Proc.
, vol.23
, pp. 2912-2915
-
-
Su, M.S.1
Semerjian, A.2
-
29
-
-
0029814276
-
Role of unphosphorylated, newly synthesized IκBβ in persistent activation of NF-κB
-
Suyang, H., R. Phillips, I. Douglas, and S. Ghosh. 1996. Role of unphosphorylated, newly synthesized IκBβ in persistent activation of NF-κB. Mol. Cell. Biol. 16:5444-5449.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 5444-5449
-
-
Suyang, H.1
Phillips, R.2
Douglas, I.3
Ghosh, S.4
-
30
-
-
0028986194
-
IκB-β regulates the persistent response in a biphasic activation of NF-κB
-
Thompson, J. E., R. J. Phillips, H. Erdjument-Bromage, P. Tempst, and S. Ghosh. 1995. IκB-β regulates the persistent response in a biphasic activation of NF-κB. Cell 80:573-582.
-
(1995)
Cell
, vol.80
, pp. 573-582
-
-
Thompson, J.E.1
Phillips, R.J.2
Erdjument-Bromage, H.3
Tempst, P.4
Ghosh, S.5
-
31
-
-
0028978032
-
Phosphorylation of human IκB-α on serines 32 and 36 controls IκB-α proteolysis and NF-κB activation in response to diverse stimuli
-
Traenckner, E. B., H. L. Pahl, T. Henkel, K. N. Schmidt, S. Wilk, and P. A. Baeuerle. 1995. Phosphorylation of human IκB-α on serines 32 and 36 controls IκB-α proteolysis and NF-κB activation in response to diverse stimuli. EMBO J. 14:2876-2883.
-
(1995)
EMBO J.
, vol.14
, pp. 2876-2883
-
-
Traenckner, E.B.1
Pahl, H.L.2
Henkel, T.3
Schmidt, K.N.4
Wilk, S.5
Baeuerle, P.A.6
-
32
-
-
0019402464
-
Monoclonal anti-human T lymphocyte antibodies: Enumeration and characterization of T cell subsets
-
Van Wauwe, J., and J. G. Goossens. 1981. Monoclonal anti-human T lymphocyte antibodies: enumeration and characterization of T cell subsets. Immunology 42:157-164.
-
(1981)
Immunology
, vol.42
, pp. 157-164
-
-
Van Wauwe, J.1
Goossens, J.G.2
-
33
-
-
0028907128
-
FK506 inhibits antigen receptor-mediated induction of c-Rel in B and T lymphoid cells
-
Venkataraman, L., S. J. Burakoff, and R. Sen. 1995. FK506 inhibits antigen receptor-mediated induction of c-Rel in B and T lymphoid cells. J. Exp. Med. 181:1091-1099.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 1091-1099
-
-
Venkataraman, L.1
Burakoff, S.J.2
Sen, R.3
-
34
-
-
0026332710
-
Activation of interleukin-2 gene transcription via the T-cell surface molecule CD28 is mediated through an NF-κB-like response element
-
Verweij, C. L., M. Geerts, and L. A. Aarden. 1991. Activation of interleukin-2 gene transcription via the T-cell surface molecule CD28 is mediated through an NF-κB-like response element. J. Biol. Chem. 266:14179-14182.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 14179-14182
-
-
Verweij, C.L.1
Geerts, M.2
Aarden, L.A.3
-
35
-
-
0030907779
-
c-Rel is a target of pentoxifylline-mediated inhibition of T-lymphocyte activation
-
Wang, W., W. F. Tam, C. C. W. Hughes, S. Rath, and R. Sen. 1997. c-Rel is a target of pentoxifylline-mediated inhibition of T-lymphocyte activation. Immunity 6:165-174.
-
(1997)
Immunity
, vol.6
, pp. 165-174
-
-
Wang, W.1
Tam, W.F.2
Hughes, C.C.W.3
Rath, S.4
Sen, R.5
-
37
-
-
0028068807
-
Positive and negative regulation of IL-2 gene expression: Role of multiple regulatory sites
-
Zhang, L., and G. J. Nabel. 1994. Positive and negative regulation of IL-2 gene expression: role of multiple regulatory sites. Cytokine 6:221-228.
-
(1994)
Cytokine
, vol.6
, pp. 221-228
-
-
Zhang, L.1
Nabel, G.J.2
|