메뉴 건너뛰기




Volumn 15, Issue , 2016, Pages 83-92

Transcriptome analysis reveals that up-regulation of the fatty acid synthase gene promotes the accumulation of docosahexaenoic acid in Schizochytrium sp. S056 when glycerol is used

Author keywords

Acetyl CoA; Docosahexaenoic acid; Fatty acid synthase; Glycerol; Schizochytrium sp.; Transcriptome analysis

Indexed keywords


EID: 84959360688     PISSN: 22119264     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.algal.2016.02.007     Document Type: Article
Times cited : (61)

References (69)
  • 1
    • 4744369936 scopus 로고    scopus 로고
    • The health benefits of omega-3 polyunsaturated fatty acids: a review of the evidence
    • Ruxton C., Reed S.C., Simpson M., Millington K.J. The health benefits of omega-3 polyunsaturated fatty acids: a review of the evidence. J. Hum. Nutr. Diet. 2004, 17:449-459.
    • (2004) J. Hum. Nutr. Diet. , vol.17 , pp. 449-459
    • Ruxton, C.1    Reed, S.C.2    Simpson, M.3    Millington, K.J.4
  • 2
    • 58149292278 scopus 로고    scopus 로고
    • Modulation of inflammatory cytokines by omega-3 fatty acids
    • Kang J.X., Weylandt K.H. Modulation of inflammatory cytokines by omega-3 fatty acids. Subcell. Biochem. 2008, 49:133-143.
    • (2008) Subcell. Biochem. , vol.49 , pp. 133-143
    • Kang, J.X.1    Weylandt, K.H.2
  • 3
    • 84959351590 scopus 로고    scopus 로고
    • Does docosahexaenoic acid play a role in infant malnutrition in the children of Fulani nomads in Northern Nigeria?
    • Glew R.H., VanderJagt D.J. Does docosahexaenoic acid play a role in infant malnutrition in the children of Fulani nomads in Northern Nigeria?. J. Med. Trop. 2013, 15:69.
    • (2013) J. Med. Trop. , vol.15 , pp. 69
    • Glew, R.H.1    VanderJagt, D.J.2
  • 5
    • 84887150216 scopus 로고    scopus 로고
    • Long-chain polyunsaturated fatty acids (LCPUFA) from genesis to senescence: the influence of LCPUFA on neural development, aging, and neurodegeneration
    • Janssen C.I., Kiliaan A.J. Long-chain polyunsaturated fatty acids (LCPUFA) from genesis to senescence: the influence of LCPUFA on neural development, aging, and neurodegeneration. Prog. Lipid Res. 2014, 53:1-17.
    • (2014) Prog. Lipid Res. , vol.53 , pp. 1-17
    • Janssen, C.I.1    Kiliaan, A.J.2
  • 6
  • 7
    • 84857224159 scopus 로고    scopus 로고
    • Health benefits of n-3 polyunsaturated fatty acids: eicosapentaenoic acid and docosahexaenoic acid
    • Siriwardhana N., Kalupahana N.S., Moustaid-Moussa N. Health benefits of n-3 polyunsaturated fatty acids: eicosapentaenoic acid and docosahexaenoic acid. Adv. Food Nutr. Res. 2012, 65:211-222.
    • (2012) Adv. Food Nutr. Res. , vol.65 , pp. 211-222
    • Siriwardhana, N.1    Kalupahana, N.S.2    Moustaid-Moussa, N.3
  • 10
    • 84911087658 scopus 로고    scopus 로고
    • A techno-economic analysis of industrial production of marine microalgae as a source of EPA and DHA-rich raw material for aquafeed: research challenges and possibilities
    • Chauton M.S., Reitan K.I., Norsker N.H., Tveterås R., Kleivdal H.T. A techno-economic analysis of industrial production of marine microalgae as a source of EPA and DHA-rich raw material for aquafeed: research challenges and possibilities. Aquaculture 2015, 436:95-103.
    • (2015) Aquaculture , vol.436 , pp. 95-103
    • Chauton, M.S.1    Reitan, K.I.2    Norsker, N.H.3    Tveterås, R.4    Kleivdal, H.T.5
  • 11
    • 0032946222 scopus 로고    scopus 로고
    • Biosynthesis and regulation of microbial polyunsaturated fatty acid production
    • Certik M., Shimizu S. Biosynthesis and regulation of microbial polyunsaturated fatty acid production. J. Biosci. Bioeng. 1999, 87:1-14.
    • (1999) J. Biosci. Bioeng. , vol.87 , pp. 1-14
    • Certik, M.1    Shimizu, S.2
  • 12
    • 84905755502 scopus 로고    scopus 로고
    • Environmental pollutants: downgrading the fish food stock affects chronic disease risk
    • Jacobs D.R., Ruzzin J., Lee D.H. Environmental pollutants: downgrading the fish food stock affects chronic disease risk. J. Intern. Med. 2014, 276:240-242.
    • (2014) J. Intern. Med. , vol.276 , pp. 240-242
    • Jacobs, D.R.1    Ruzzin, J.2    Lee, D.H.3
  • 13
    • 84898881715 scopus 로고    scopus 로고
    • Culturable diversity and biochemical features of thraustochytrids from coastal waters of Southern China
    • Liu Y., Singh P., Sun Y., Luan S., Wang G. Culturable diversity and biochemical features of thraustochytrids from coastal waters of Southern China. Appl. Microbiol. Biotechnol. 2014, 98:3241-3255.
    • (2014) Appl. Microbiol. Biotechnol. , vol.98 , pp. 3241-3255
    • Liu, Y.1    Singh, P.2    Sun, Y.3    Luan, S.4    Wang, G.5
  • 14
    • 84902367759 scopus 로고    scopus 로고
    • Comparison of Thraustochytrids Aurantiochytrium sp., Schizochytrium sp., Thraustochytrium sp., and Ulkenia sp. for production of biodiesel, long-chain omega-3 oils, and exopolysaccharide
    • Lee Chang K.J., Nichols C., Blackburn S., Dunstan G., Koutoulis A., Nichols P. Comparison of Thraustochytrids Aurantiochytrium sp., Schizochytrium sp., Thraustochytrium sp., and Ulkenia sp. for production of biodiesel, long-chain omega-3 oils, and exopolysaccharide. Mar. Biotechnol. 2014, 16:396-411.
    • (2014) Mar. Biotechnol. , vol.16 , pp. 396-411
    • Lee Chang, K.J.1    Nichols, C.2    Blackburn, S.3    Dunstan, G.4    Koutoulis, A.5    Nichols, P.6
  • 15
  • 17
    • 84867698577 scopus 로고    scopus 로고
    • Omega-3 biotechnology: errors and omissions
    • Ratledge C. Omega-3 biotechnology: errors and omissions. Biotechnol. Adv. 2012, 30:1746-1747.
    • (2012) Biotechnol. Adv. , vol.30 , pp. 1746-1747
    • Ratledge, C.1
  • 18
    • 33750483272 scopus 로고    scopus 로고
    • Fatty acid production in Schizochytrium sp.: involvement of a polyunsaturated fatty acid synthase and a type I fatty acid synthase
    • Hauvermale A., Kuner J., Rosenzweig B., Guerra D., Diltz S., Metz J.G. Fatty acid production in Schizochytrium sp.: involvement of a polyunsaturated fatty acid synthase and a type I fatty acid synthase. Lipids 2006, 41:739-747.
    • (2006) Lipids , vol.41 , pp. 739-747
    • Hauvermale, A.1    Kuner, J.2    Rosenzweig, B.3    Guerra, D.4    Diltz, S.5    Metz, J.G.6
  • 19
    • 84889248345 scopus 로고    scopus 로고
    • Pathways of lipid metabolism in marine algae, co-expression network, bottlenecks and candidate genes for enhanced production of EPA and DHA in species of Chromista
    • Mühlroth A., Li K., Røkke G., Winge P., Olsen Y., Hohmann-Marriott M.F., Vadstein O., Bones A.M. Pathways of lipid metabolism in marine algae, co-expression network, bottlenecks and candidate genes for enhanced production of EPA and DHA in species of Chromista. Mar. Drugs 2013, 11:4662-4697.
    • (2013) Mar. Drugs , vol.11 , pp. 4662-4697
    • Mühlroth, A.1    Li, K.2    Røkke, G.3    Winge, P.4    Olsen, Y.5    Hohmann-Marriott, M.F.6    Vadstein, O.7    Bones, A.M.8
  • 21
    • 10044264487 scopus 로고    scopus 로고
    • Fatty acid biosynthesis in microorganisms being used for single cell oil production
    • Ratledge C. Fatty acid biosynthesis in microorganisms being used for single cell oil production. Biochimie 2004, 86:807-815.
    • (2004) Biochimie , vol.86 , pp. 807-815
    • Ratledge, C.1
  • 22
    • 84867699760 scopus 로고    scopus 로고
    • Omega-3 biotechnology: thraustochytrids as a novel source of omega-3 oils
    • Gupta A., Barrow C.J., Puri M. Omega-3 biotechnology: thraustochytrids as a novel source of omega-3 oils. Biotechnol. Adv. 2012, 30:1733-1745.
    • (2012) Biotechnol. Adv. , vol.30 , pp. 1733-1745
    • Gupta, A.1    Barrow, C.J.2    Puri, M.3
  • 23
    • 84903560073 scopus 로고    scopus 로고
    • Ecological dynamics and biotechnological implications of thraustochytrids from marine habitats
    • Singh P., Liu Y., Li L., Wang G. Ecological dynamics and biotechnological implications of thraustochytrids from marine habitats. Appl. Microbiol. Biotechnol. 2014, 98:5789-5805.
    • (2014) Appl. Microbiol. Biotechnol. , vol.98 , pp. 5789-5805
    • Singh, P.1    Liu, Y.2    Li, L.3    Wang, G.4
  • 24
    • 57749195712 scopus 로고    scopus 로고
    • RNA-Seq: a revolutionary tool for transcriptomics
    • Wang Z., Gerstein M., Snyder M. RNA-Seq: a revolutionary tool for transcriptomics. Nat. Rev. Genet. 2009, 10:57-63.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 57-63
    • Wang, Z.1    Gerstein, M.2    Snyder, M.3
  • 25
    • 64749084488 scopus 로고    scopus 로고
    • An approach to transcriptome analysis of non-model organisms using short-read sequences
    • Collins L.J., Biggs P.J., Voelckel C., Joly S. An approach to transcriptome analysis of non-model organisms using short-read sequences. Genome Inform. 2008, 21:3-14.
    • (2008) Genome Inform. , vol.21 , pp. 3-14
    • Collins, L.J.1    Biggs, P.J.2    Voelckel, C.3    Joly, S.4
  • 26
    • 37749031255 scopus 로고    scopus 로고
    • Next-generation sequencing transforms today's biology
    • Schuster S.C. Next-generation sequencing transforms today's biology. Nat. Methods 2008, 5:16-18.
    • (2008) Nat. Methods , vol.5 , pp. 16-18
    • Schuster, S.C.1
  • 27
    • 67349209853 scopus 로고    scopus 로고
    • Next-generation DNA sequencing techniques
    • Ansorge W.J. Next-generation DNA sequencing techniques. New Biotechnol. 2009, 25:195-203.
    • (2009) New Biotechnol. , vol.25 , pp. 195-203
    • Ansorge, W.J.1
  • 28
    • 67449141880 scopus 로고    scopus 로고
    • RNA-Seq - quantitative measurement of expression through massively parallel RNA-sequencing
    • Wilhelm B.T., Landry J. RNA-Seq - quantitative measurement of expression through massively parallel RNA-sequencing. Methods 2009, 48:249-257.
    • (2009) Methods , vol.48 , pp. 249-257
    • Wilhelm, B.T.1    Landry, J.2
  • 29
    • 84860485003 scopus 로고    scopus 로고
    • Optimizing de novo transcriptome assembly from short-read RNA-Seq data: a comparative study
    • Zhao Q., Wang Y., Kong Y., Luo D., Li X., Hao P. Optimizing de novo transcriptome assembly from short-read RNA-Seq data: a comparative study. BMC Bioinformatics 2011, 12:S2.
    • (2011) BMC Bioinformatics , vol.12 , pp. S2
    • Zhao, Q.1    Wang, Y.2    Kong, Y.3    Luo, D.4    Li, X.5    Hao, P.6
  • 30
    • 84869014474 scopus 로고    scopus 로고
    • A comprehensive comparison of RNA-Seq-based transcriptome analysis from reads to differential gene expression and cross-comparison with microarrays: a case study in Saccharomyces cerevisiae
    • Nookaew I., Papini M., Pornputtpong N., Scalcinati G., Fagerberg L., Uhlén M., Nielsen J. A comprehensive comparison of RNA-Seq-based transcriptome analysis from reads to differential gene expression and cross-comparison with microarrays: a case study in Saccharomyces cerevisiae. Nucleic Acids Res. 2012, s804.
    • (2012) Nucleic Acids Res. , pp. s804
    • Nookaew, I.1    Papini, M.2    Pornputtpong, N.3    Scalcinati, G.4    Fagerberg, L.5    Uhlén, M.6    Nielsen, J.7
  • 31
    • 22544443075 scopus 로고    scopus 로고
    • Effect of culture conditions on docosahexaenoic acid production by Schizochytrium sp. S31
    • Wu S., Yu S., Lin L. Effect of culture conditions on docosahexaenoic acid production by Schizochytrium sp. S31. Process Biochem. 2005, 40:3103-3108.
    • (2005) Process Biochem. , vol.40 , pp. 3103-3108
    • Wu, S.1    Yu, S.2    Lin, L.3
  • 33
    • 84879549673 scopus 로고    scopus 로고
    • Production of lipids containing high levels of docosahexaenoic acid from empty palm fruit bunches by Aurantiochytrium sp. KRS101
    • Hong W., Yu A., Heo S., Oh B., Kim C.H., Sohn J., Yang J., Kondo A., Seo J. Production of lipids containing high levels of docosahexaenoic acid from empty palm fruit bunches by Aurantiochytrium sp. KRS101. Bioprocess Biosyst. Eng. 2013, 36:959-963.
    • (2013) Bioprocess Biosyst. Eng. , vol.36 , pp. 959-963
    • Hong, W.1    Yu, A.2    Heo, S.3    Oh, B.4    Kim, C.H.5    Sohn, J.6    Yang, J.7    Kondo, A.8    Seo, J.9
  • 34
    • 84901394382 scopus 로고    scopus 로고
    • Evaluation of bread crumbs as a potential carbon source for the growth of thraustochytrid species for oil and omega-3 production
    • Thyagarajan T., Puri M., Vongsvivut J., Barrow C.J. Evaluation of bread crumbs as a potential carbon source for the growth of thraustochytrid species for oil and omega-3 production. Nutrients 2014, 6:2104-2114.
    • (2014) Nutrients , vol.6 , pp. 2104-2114
    • Thyagarajan, T.1    Puri, M.2    Vongsvivut, J.3    Barrow, C.J.4
  • 35
    • 37549070353 scopus 로고    scopus 로고
    • The glycerin glut: options for the value-added conversion of crude glycerol resulting from biodiesel production
    • Johnson D.T., Taconi K.A. The glycerin glut: options for the value-added conversion of crude glycerol resulting from biodiesel production. Environ. Prog. 2007, 26:338-348.
    • (2007) Environ. Prog. , vol.26 , pp. 338-348
    • Johnson, D.T.1    Taconi, K.A.2
  • 36
    • 35148846126 scopus 로고    scopus 로고
    • A laboratory study of producing docosahexaenoic acid from biodiesel-waste glycerol by microalgal fermentation
    • Chi Z., Pyle D., Wen Z., Frear C., Chen S. A laboratory study of producing docosahexaenoic acid from biodiesel-waste glycerol by microalgal fermentation. Process Biochem. 2007, 42:1537-1545.
    • (2007) Process Biochem. , vol.42 , pp. 1537-1545
    • Chi, Z.1    Pyle, D.2    Wen, Z.3    Frear, C.4    Chen, S.5
  • 37
    • 84865405055 scopus 로고    scopus 로고
    • A fermentation strategy for producing docosahexaenoic acid in Aurantiochytrium limacinum SR21 and increasing C22:6 proportions in total fatty acid
    • Huang T.Y., Lu W.C., Chu I.M. A fermentation strategy for producing docosahexaenoic acid in Aurantiochytrium limacinum SR21 and increasing C22:6 proportions in total fatty acid. Bioresour. Technol. 2012, 123:8-14.
    • (2012) Bioresour. Technol. , vol.123 , pp. 8-14
    • Huang, T.Y.1    Lu, W.C.2    Chu, I.M.3
  • 38
    • 84880510853 scopus 로고    scopus 로고
    • High cell density cultivation of a novel Aurantiochytrium sp. strain TC 20 in a fed-batch system using glycerol to produce feedstock for biodiesel and omega-3 oils
    • Lee Chang K.J., Dumsday G., Nichols P.D., Dunstan G.A., Blackburn S.I., Koutoulis A. High cell density cultivation of a novel Aurantiochytrium sp. strain TC 20 in a fed-batch system using glycerol to produce feedstock for biodiesel and omega-3 oils. Appl. Microbiol. Biotechnol. 2013, 97:6907-6918.
    • (2013) Appl. Microbiol. Biotechnol. , vol.97 , pp. 6907-6918
    • Lee Chang, K.J.1    Dumsday, G.2    Nichols, P.D.3    Dunstan, G.A.4    Blackburn, S.I.5    Koutoulis, A.6
  • 39
    • 84973483441 scopus 로고    scopus 로고
    • Improved synthesis of docosahexaenoic acid (DHA) using Schizochytrium limacinum SR21 and sustainable media
    • Patil K.P., Gogate P.R. Improved synthesis of docosahexaenoic acid (DHA) using Schizochytrium limacinum SR21 and sustainable media. Chem. Eng. J. 2015, 268:187-196.
    • (2015) Chem. Eng. J. , vol.268 , pp. 187-196
    • Patil, K.P.1    Gogate, P.R.2
  • 40
    • 84931576775 scopus 로고    scopus 로고
    • A novel feedstock for biodiesel production: the application of palmitic acid from Schizochytrium
    • Chen W., Ma L., Zhou P., Zhu Y., Wang X., Luo X., Bao Z., Yu L. A novel feedstock for biodiesel production: the application of palmitic acid from Schizochytrium. Energy 2015, 86:128-138.
    • (2015) Energy , vol.86 , pp. 128-138
    • Chen, W.1    Ma, L.2    Zhou, P.3    Zhu, Y.4    Wang, X.5    Luo, X.6    Bao, Z.7    Yu, L.8
  • 41
    • 17744376044 scopus 로고    scopus 로고
    • Enhancement of polyunsaturated fatty acid production by cerulenin treatment in polyunsaturated fatty acid-producing bacteria
    • Morita N., Nishida T., Tanaka M., Yano Y., Okuyama H. Enhancement of polyunsaturated fatty acid production by cerulenin treatment in polyunsaturated fatty acid-producing bacteria. Biotechnol. Lett. 2005, 27:389-393.
    • (2005) Biotechnol. Lett. , vol.27 , pp. 389-393
    • Morita, N.1    Nishida, T.2    Tanaka, M.3    Yano, Y.4    Okuyama, H.5
  • 44
    • 24644503098 scopus 로고    scopus 로고
    • Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research
    • Conesa A., Götz S., García-Gómez J.M., Terol J., Talón M., Robles M. Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research. Bioinformatics 2005, 21:3674-3676.
    • (2005) Bioinformatics , vol.21 , pp. 3674-3676
    • Conesa, A.1    Götz, S.2    García-Gómez, J.M.3    Terol, J.4    Talón, M.5    Robles, M.6
  • 46
    • 0030681260 scopus 로고    scopus 로고
    • The significance of digital gene expression profiles
    • Audic S., Claverie J. The significance of digital gene expression profiles. Genome Res. 1997, 7:986-995.
    • (1997) Genome Res. , vol.7 , pp. 986-995
    • Audic, S.1    Claverie, J.2
  • 47
    • 84879142745 scopus 로고    scopus 로고
    • Characterization of Pythium transcriptome and gene expression analysis at different stages of fermentation
    • Zhu Y., Zhou P., Hu J., Zhang R., Ren L., Li M., Ning F., Chen W., Yu L. Characterization of Pythium transcriptome and gene expression analysis at different stages of fermentation. PLoS One 2013, 8.
    • (2013) PLoS One , vol.8
    • Zhu, Y.1    Zhou, P.2    Hu, J.3    Zhang, R.4    Ren, L.5    Li, M.6    Ning, F.7    Chen, W.8    Yu, L.9
  • 49
    • 10644226842 scopus 로고    scopus 로고
    • Direct FAME synthesis for rapid total lipid analysis from fish oil and cod liver oil
    • Indarti E., Majid M.I.A., Hashim R., Chong A. Direct FAME synthesis for rapid total lipid analysis from fish oil and cod liver oil. J. Food Compos. Anal. 2005, 18:161-170.
    • (2005) J. Food Compos. Anal. , vol.18 , pp. 161-170
    • Indarti, E.1    Majid, M.I.A.2    Hashim, R.3    Chong, A.4
  • 50
    • 69249221546 scopus 로고    scopus 로고
    • Enhanced docosahexaenoic acid production by reinforcing acetyl-CoA and NADPH supply in Schizochytrium sp. HX-308
    • Ren L., Huang H., Xiao A., Lian M., Jin L., Ji X. Enhanced docosahexaenoic acid production by reinforcing acetyl-CoA and NADPH supply in Schizochytrium sp. HX-308. Bioprocess Biosyst. Eng. 2009, 32:837-843.
    • (2009) Bioprocess Biosyst. Eng. , vol.32 , pp. 837-843
    • Ren, L.1    Huang, H.2    Xiao, A.3    Lian, M.4    Jin, L.5    Ji, X.6
  • 51
    • 77955233622 scopus 로고    scopus 로고
    • Microbial production of docosahexaenoic acid by a low temperature-adaptive strain Thraustochytriidae sp. Z105: screening and optimization
    • Zhou P.P., Lu M.B., Li W., Yu L.J. Microbial production of docosahexaenoic acid by a low temperature-adaptive strain Thraustochytriidae sp. Z105: screening and optimization. J. Basic Microbiol. 2010, 50:380-387.
    • (2010) J. Basic Microbiol. , vol.50 , pp. 380-387
    • Zhou, P.P.1    Lu, M.B.2    Li, W.3    Yu, L.J.4
  • 52
    • 63649111659 scopus 로고    scopus 로고
    • Amino acids: metabolism, functions, and nutrition
    • Wu G. Amino acids: metabolism, functions, and nutrition. Amino Acids 2009, 37:1-17.
    • (2009) Amino Acids , vol.37 , pp. 1-17
    • Wu, G.1
  • 54
    • 84902096405 scopus 로고    scopus 로고
    • Microbial production of amino acids and derived chemicals: synthetic biology approaches to strain development
    • Wendisch V.F. Microbial production of amino acids and derived chemicals: synthetic biology approaches to strain development. Curr. Opin. Biotechnol. 2014, 30:51-58.
    • (2014) Curr. Opin. Biotechnol. , vol.30 , pp. 51-58
    • Wendisch, V.F.1
  • 55
    • 20344373417 scopus 로고    scopus 로고
    • Overview of the molecular and biochemical basis of branched-chain amino acid catabolism
    • Harris R.A., Joshi M., Jeoung N.H., Obayashi M. Overview of the molecular and biochemical basis of branched-chain amino acid catabolism. J. Nutr. 2005, 135:1527S-1530S.
    • (2005) J. Nutr. , vol.135 , pp. 1527S-1530S
    • Harris, R.A.1    Joshi, M.2    Jeoung, N.H.3    Obayashi, M.4
  • 57
    • 0029099953 scopus 로고
    • Regulation of glutaminase activity and glutamine metabolism
    • Curthoys N.P., Watford M. Regulation of glutaminase activity and glutamine metabolism. Annu. Rev. Nutr. 1995, 15:133-159.
    • (1995) Annu. Rev. Nutr. , vol.15 , pp. 133-159
    • Curthoys, N.P.1    Watford, M.2
  • 58
    • 0017137380 scopus 로고
    • The antibiotic cerulenin, a novel tool for biochemistry as an inhibitor of fatty acid synthesis
    • Omura S. The antibiotic cerulenin, a novel tool for biochemistry as an inhibitor of fatty acid synthesis. Bacteriol. Rev. 1976, 40:681-697.
    • (1976) Bacteriol. Rev. , vol.40 , pp. 681-697
    • Omura, S.1
  • 59
    • 53549117446 scopus 로고    scopus 로고
    • Expressed sequence tag analysis of marine fungus Schizochytrium producing docosahexaenoic acid
    • Huang J., Jiang X., Zhang X., Chen W., Tian B., Shu Z., Hu S. Expressed sequence tag analysis of marine fungus Schizochytrium producing docosahexaenoic acid. J. Biotechnol. 2008, 138:9-16.
    • (2008) J. Biotechnol. , vol.138 , pp. 9-16
    • Huang, J.1    Jiang, X.2    Zhang, X.3    Chen, W.4    Tian, B.5    Shu, Z.6    Hu, S.7
  • 60
    • 67650710823 scopus 로고    scopus 로고
    • Characterization of both polyunsaturated fatty acid biosynthetic pathways in Schizochytrium sp
    • Lippmeier J.C., Crawford K.S., Owen C.B., Rivas A.A., Metz J.G., Apt K.E. Characterization of both polyunsaturated fatty acid biosynthetic pathways in Schizochytrium sp. Lipids 2009, 44:621-630.
    • (2009) Lipids , vol.44 , pp. 621-630
    • Lippmeier, J.C.1    Crawford, K.S.2    Owen, C.B.3    Rivas, A.A.4    Metz, J.G.5    Apt, K.E.6
  • 61
    • 84903728771 scopus 로고    scopus 로고
    • The role of malic enzyme as the provider of NADPH in oleaginous microorganisms: a reappraisal and unsolved problems
    • Ratledge C. The role of malic enzyme as the provider of NADPH in oleaginous microorganisms: a reappraisal and unsolved problems. Biotechnol. Lett. 2014, 1-12.
    • (2014) Biotechnol. Lett. , pp. 1-12
    • Ratledge, C.1
  • 63
    • 84878492901 scopus 로고    scopus 로고
    • Single-cell oils as a source of omega-3 fatty acids: an overview of recent advances
    • Armenta R.E., Valentine M.C. Single-cell oils as a source of omega-3 fatty acids: an overview of recent advances. J. Am. Oil Chem. Soc. 2013, 90:167-182.
    • (2013) J. Am. Oil Chem. Soc. , vol.90 , pp. 167-182
    • Armenta, R.E.1    Valentine, M.C.2
  • 64
    • 0032487108 scopus 로고    scopus 로고
    • Kinetic, dynamic, and pathway studies of glycerol metabolism by Klebsiella pneumoniae in anaerobic continuous culture: III. Enzymes and fluxes of glycerol dissimilation and 1,3-propanediol formation
    • Ahrens K., Menzel K., Zeng A.P., Deckwer W.D. Kinetic, dynamic, and pathway studies of glycerol metabolism by Klebsiella pneumoniae in anaerobic continuous culture: III. Enzymes and fluxes of glycerol dissimilation and 1,3-propanediol formation. Biotechnol. Bioeng. 1998, 59:544-552.
    • (1998) Biotechnol. Bioeng. , vol.59 , pp. 544-552
    • Ahrens, K.1    Menzel, K.2    Zeng, A.P.3    Deckwer, W.D.4
  • 65
    • 57349088282 scopus 로고    scopus 로고
    • Glycerol: a promising and abundant carbon source for industrial microbiology
    • da Silva G.P., Mack M., Contiero J. Glycerol: a promising and abundant carbon source for industrial microbiology. Biotechnol. Adv. 2009, 27:30-39.
    • (2009) Biotechnol. Adv. , vol.27 , pp. 30-39
    • da Silva, G.P.1    Mack, M.2    Contiero, J.3
  • 68
    • 84921324786 scopus 로고    scopus 로고
    • Molecular mechanisms for photosynthetic carbon partitioning into storage neutral lipids in Nannochloropsis oceanica under nitrogen-depletion conditions
    • Jia J., Han D., Gerken H.G., Li Y., Sommerfeld M., Hu Q., Xu J. Molecular mechanisms for photosynthetic carbon partitioning into storage neutral lipids in Nannochloropsis oceanica under nitrogen-depletion conditions. Algal Res. 2015, 7:66-77.
    • (2015) Algal Res. , vol.7 , pp. 66-77
    • Jia, J.1    Han, D.2    Gerken, H.G.3    Li, Y.4    Sommerfeld, M.5    Hu, Q.6    Xu, J.7
  • 69
    • 84901321937 scopus 로고    scopus 로고
    • Choreography of transcriptomes and lipidomes of Nannochloropsis reveals the mechanisms of oil synthesis in microalgae
    • Li J., Han D., Wang D., Ning K., Jia J., Wei L., Jing X., Huang S., Chen J., Li Y. Choreography of transcriptomes and lipidomes of Nannochloropsis reveals the mechanisms of oil synthesis in microalgae. Plant Cell 2014, 26:1645-1665.
    • (2014) Plant Cell , vol.26 , pp. 1645-1665
    • Li, J.1    Han, D.2    Wang, D.3    Ning, K.4    Jia, J.5    Wei, L.6    Jing, X.7    Huang, S.8    Chen, J.9    Li, Y.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.