The effect of constitutive over-expression of insulin-like growth factor 1 on the cognitive function in aged mice

Brain Research

Volumn 1631, Issue , 2016, Pages 204-213

  Hu, Ankang ^a   Yuan, Honghua ^a   Wu, Lianlian ^a   Chen, Renjin ^a   Chen, Quangang ^a   Zhang, Tengye ^a   Wang, Zhenzhen ^a   Liu, Peng ^a   Zhu, Xiaorong ^a  

^a XUZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Aged mice; Cognitive ability; Hippocampus; IGF 1; p CaMKII; p ERK1 2

Indexed keywords

BROXURIDINE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NESTIN; SOMATOMEDIN C; INSULIN-LIKE GROWTH FACTOR-1, MOUSE; MITOGEN ACTIVATED PROTEIN KINASE; SOMATOMEDIN C RECEPTOR;

AGED; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DENTATE GYRUS; ENZYME PHOSPHORYLATION; GENE OVEREXPRESSION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LEARNING; MEMORY; MORRIS WATER MAZE TEST; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NISSL STAINING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEP-DOWN PASSIVE AVOIDANCE TEST; TRANSGENIC MOUSE; UPREGULATION; WILD TYPE MOUSE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; DRUG EFFECTS; GENE EXPRESSION; MAZE TEST; METABOLISM; NERVE CELL; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; COGNITION; DENTATE GYRUS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION; HIPPOCAMPUS; INSULIN-LIKE GROWTH FACTOR I; MAP KINASE SIGNALING SYSTEM; MAZE LEARNING; MEMORY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURAL STEM CELLS; NEUROGENESIS; NEURONS; PHOSPHORYLATION; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84959330675     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2015.11.010     Document Type: Article

References (59)

1. N.D. Åberg, and et al. Aspects of growth hormone and insulin-like growth factor-I related to neuroprotection, regeneration, and functional plasticity in the adult brain Sci. World J. 6 2006 53 80 (PubMed: 16432628)
2. J.B. Aimone, and et al. Resolving new memories: A critical look at the dentate gyrus, adult neurogenesis, and pattern separation Neuron 70 2011 589 596 (PubMed: 21609818)
3. B.N. Ames, and et al. Mitochondrial decay in aging Biochim. Biophys. Acta (BBA)-Mol. Basis Dis. 1271 1995 165 170 (PubMed: 7599204)
4. M.F. Anderson, and et al. Insulin-like growth factor-I and neurogenesis in the adult mammalian brain Dev. Brain Res. 134 2002 115 122 (PubMed: 11947942)
5. I. Andersson, and et al. Differing expression of insulin-like growth factor I in the developing and in the adult rat cerebellum Acta Physiol. Scand. 132 1988 167 173 (PubMed: 3067513)
6. Y. Arsenijevic, and S. Weiss Insulin-like growth factor-I is a differentiation factor for postmitotic CNS stem cell-derived neuronal precursors: Distinct actions from those of brain-derived neurotrophic factor J. Neurosci. 18 1998 2118 2128 (PubMed: 9482798)
7. T.V. Bliss, and T. Lømo Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path J. Physiol. 232 1973 331 356 (PubMed: 4727085)
8. K.G. Brywe, and et al. IGFI neuroprotection in the immature brain after hypoxiaischemia, involvement of Akt and GSK3β? Eur. J. Neurosci. 21 2005 1489 1502 (PubMed: 15845077)
9. D.Y. Chen, and et al. A critical role for IGF-II in memory consolidation and enhancement Nature 469 2011 491 497 (PubMed: 21270887)
10. Y.S. Choi, and et al. IGF1 receptormediated ERK/MAPK signaling couples status epilepticus to progenitor cell proliferation in the subgranular layer of the dentate gyrus Glia 56 2008 791 800 (PubMed: 18338791)
11. S. Couillard-Després Hippocampal neurogenesis and ageing Neurogenesis and Neural Plasticity 2013 Springer Berlin 343 355 (PubMed: 23065635)
12. A.J. D'Ercole, and et al. The role of the insulin-like growth factors in the central nervous system Mol. Neurobiol. 13 1996 227 255 (PubMed: 8989772)
13. M. Darnaudéry, and et al. Insulin-like growth factor 1 reduces age-related disorders induced by prenatal stress in female rats Neurobiol. Aging 27 2006 119 127 (PubMed: 16298247)
14. J.A. DErcole, and et al. Mutant mouse models of insulin-like growth factor actions in the central nervous system Neuropeptides 36 2002 209 220 (PubMed: 12359511)
15. J.D. English, and J.D. Sweatt A requirement for the mitogen-activated protein kinase cascade in hippocampal long term potentiation J. Biol. Chem. 272 1997 19103 19106 (PubMed: 9235897)
16. A.M. Fernandez, and I. Torres-Alemán The many faces of insulin-like peptide signalling in the brain Nat. Rev. Neurosci. 13 2012 225 239 (PubMed: 22430016)
17. J.R. Florini, and D.Z. Ewton Insulin acts as a somatomedin analog in stimulating myoblast growth in serum-free medium In vitro 17 1981 763 768 (PubMed: 6170569)
18. K. Fukunaga, and et al. Increased phosphorylation of Ca/Calmodulin-dependent protein kinase II and its endogenous substrates in the induction of long term potentiation J. Biol. Chem. 270 1995 6119 6124 (PubMed: 7890745)
19. 2+/calmodulin-dependent protein kinase II J. Biol. Chem. 268 1993 7863 7867 (PubMed: 8385124)
20. K.P. Giese, and et al. Autophosphorylation at Thr 286 of the αCalcium-Calmodulin Kinase II in LTP and learning Science 6 5352 1998 870 873 (PMID:9452388)
21. X. Gong, and et al. Down-regulation of IGF-1/IGF-1R in hippocampus of rats with vascular Neurosci. Lett. 513 1 2012 20 24
22. N. Harada, and et al. Resveratrol improves cognitive function in mice by increasing production of insulin-like growth factor-I in the hippocampus J. Nutr. Biochem. 22 2011 1150 1159 (PubMed: 21295960)
23. K.-S. Hung, and et al. Gene transfer of insulin-like growth factor-I providing neuroprotection after spinal cord injury in rats J. Neurosurg.: Spine 6 2007 35 46 (PubMed: 17233289)
24. 2+ stimulation of CREB-dependent transcription and ERK Nuclear translocation Neuron 21 1998 869 883 (PubMed: 9908472)
25. H.S. Kalluri, and et al. Mechanism of insulinlike growth factor Imediated proliferation of adult neural progenitor cells: Role of Akt Eur. J. Neurosci. 25 2007 1041 1048 (PubMed: 17331200)
26. T. Kawano, and et al. Neuroprotective effect of sodium orthovanadate on delayed neuronal death after transient forebrain ischemia in gerbil hippocampus J. Cereb. Blood Flow Metab. 21 2001 1268 1280 (PubMed: 11702042)
27. S. Kizhakke Madathil, and et al. Temporal and regional changes in IGF-1/IGF-1R signaling in the mouse brain after traumatic brain injury J. Neurotrauma 27 2010 95 107 (PubMed: 19751099)
28. C.H. Lee, and et al. Decreased insulin-like growth factor-I and Its receptor expression in the hippocampus and somatosensory cortex of the aged mouse Neurochem. Res. 39 2014 770 776 (PubMed: 24577837)
29. S.W. Lee, and et al. New neurons in an aged brain Behav. Brain Res. 227 2012 497 507 (PubMed: 22024433)
30. G.M. Leinninger, and et al. Phosphatidylinositol 3-kinase and Akt effectors mediate insulin-like growth factor-I neuroprotection in dorsal root ganglia neurons FASEB J. 18 2004 1544 1546 (PubMed: 15319368)
31. R. Lichtenwalner, and et al. Intracerebroventricular infusion of insulin-like growth factor-I ameliorates the age-related decline in hippocampal neurogenesis Neuroscience 107 2001 603 613 (PubMed: 11720784)
32. 2+/calmodulin-dependent protein kinase II and mitogen-activated protein kinase activation in hippocampal long-term potentiation J. Neurosci. 19 1999 8292 8299 (PubMed: 10493730)
33. J. Liu, and A. Mori Stress, aging, and brain oxidative damage Neurochem. Res. 24 1999 1479 1497 (PubMed: 10555789)
34. G.M. Martin, and et al. Genetic analysis of ageing: Role of oxidative damage and environmental stresses Nat. Genet. 13 1996 25 34 (PubMed: 8673100)
35. S. Moriguchi, and et al. Decreased calcium/calmodulin-dependent protein kinase II and protein kinase C activities mediate impairment of hippocampal long-term potentiation in the olfactory bulbectomized mice J. Neurochem. 97 2006 22 29 (PubMed: 16515554)
36. S. Moriguchi, and et al. Nefiracetam activation of CaM kinase II and protein kinase C mediated by NMDA and metabotropic glutamate receptors in olfactory bulbectomized mice J. Neurochem. 110 2009 170 181 (PubMed: 19457128)
37. S. Moriguchi, and et al. CaMKII activity is essential for improvement of memory-related behaviors by chronic rivastigmine treatment J. Neurochem. 128 2014 927 937 (PubMed: 24164423)
38. S. Moriguchi, and et al. Novel nootropic drug sunifiram enhances hippocampal synaptic efficacy via glycine-binding site of N-methyl-D-aspartate receptor Hippocampus 23 2013 942 951 (PubMed: 23733502)
39. R. Morris, and et al. Selective impairment of learning and blockade of long-term potentiation by an N-methyl-d-aspartate receptor antagonist, AP5 Nature 319 1986 774 776 (PubMed: 2869411)
40. R. Morris Developments of a water-maze procedure for studying spatial learning in the rat J. Neurosci. Methods 11 1984 47 60 (PubMed: 6471907)
41. A.P. Muller, and et al. Reduced brain insulin-like growth factor I function during aging Mol. Cell. Neurosci. 49 2012 9 12 (PubMed: 21807098)
42. J.R. OKusky, and et al. Insulin-like growth factor-I promotes neurogenesis and synaptogenesis in the hippocampal dentate gyrus during postnatal development J. Neurosci. 20 2000 8435 8442 (PubMed: 11069951)
43. D. Ozdemir, and et al. Relationship between circulating IGF-1 levels and traumatic brain injury-induced hippocampal damage and cognitive dysfunction in immature rats Neurosci. Lett. 507 2012 84 89 (PubMed: 22172933)
44. M. Pascual-Lucas, and et al. Insulin-like growth factor 2 reverses memory and synaptic deficits in APP transgenic mice EMBO Mol. Med. 6 10 2014 1246 1262 (PubMed: 25100745)
45. H.F. Poon, and et al. Free radicals and brain aging Clin. Geriatr Med. 20 2004 329 359 (PubMed: 15182885)
46. M. Ramsey, and et al. Growth hormone treatment attenuates age-related changes in hippocampal short-term plasticity and spatial learning Neuroscience 129 2004 119 127 (PubMed: 15489035)
47. P. Rotwein, and et al. Differential expression of insulin-like growth factor genes in rat central nervous system Proc. Natl. Acad. Sci. 85 1988 265 269 (PubMed: 3422422)
48. M.J. Schmeisser, and et al. IkappaB kinase/nuclear factor kappaB-dependent insulin-like growth factor 2 (Igf2) expression regulates synapse formation and spine maturation via Igf2 receptor signaling J. Neurosci. 32 2012 5688 5703 (PubMed: 22514330)
49. W. Sonntag, and et al. Alterations in insulin-like growth factor-1 gene and protein expression and type 1 insulin-like growth factor receptors in the brains of ageing rats Neuroscience 88 1999 269 279 (PubMed: 10051206)
50. W.E. Sonntag, and et al. The effects of growth hormone and IGF-1 deficiency on cerebrovascular and brain ageing J. Anat. 197 2000 575 585 (PubMed: 11197531)
51. W.E. Sonntag, and et al. Decreased pulsatile release of growth hormone in old male rats Endocrinology 107 1980 1875 1879 (PubMed: 7428695)
52. S.A. Stern, and et al. The effect of insulin and insulin-like growth factors on hippocampus-and amygdala-dependent long-term memory formation Learn. Mem. 21 10 2014 556 563 (PubMed: 25227250)
53. A. Stuchlik Dynamic learning and memory, synaptic plasticity and neurogenesis: An update Front. Behav. Neurosci. 8 2014 (PubMed: 24744707)
54. N.E. Supeno, and et al. IGF-1 acts as controlling switch for long-term proliferation and maintenance of EGF/FGF-responsive striatal neural stem cells Int. J. Med. Sci. 10 2013 522 (PubMed: 23532711)
55. J. Tschopp, and et al. Inhibition of fas death signals by FLIPs Curr. Opin. Immunol. 10 1998 552 558 (PubMed: 9794838)
56. L.G. Valiant The hippocampus as a stable memory allocator for cortex Neural Comput. 24 2012 2873 2899 (PubMed: 22920849)
57. A.M. Vincent, and et al. IGF-I prevents glutamate-induced motor neuron programmed cell death Neurobiol. Dis. 16 2004 407 416 (PubMed: 15193297)
58. Z. Xia, and D.R. Storm The role of calmodulin as a signal integrator for synaptic plasticity Nat. Rev. Neurosci. 6 2005 267 276 (PubMed: 15803158)
59. H. Yuan, and et al. The regulatory mechanism of neurogenesis by IGF-1 in adult mice Mol. Neurobiol. 2014 1 11 (PubMed: 24777577)