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Volumn 27, Issue 1, 2010, Pages 95-107

Temporal and regional changes in IGF-1/IGF-1R signaling in the mouse brain after traumatic brain injury

Author keywords

Akt; Axonal injury; Blood vessels; Controlled cortical impact; Neurotrophic factor

Indexed keywords

NEUROTROPHIC FACTOR; PROTEIN KINASE B; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

EID: 76349116807     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2009.1002     Document Type: Article
Times cited : (85)

References (63)
  • 1
    • 33645222277 scopus 로고    scopus 로고
    • Aspects of growth hormone and insulin-like growth factor-I related to neuroprotection, regeneration, and functional plasticity in the adult brain
    • Aberg, N.D., Brywe, K.G., and Isgaard, J. (2006). Aspects of growth hormone and insulin-like growth factor-I related to neuroprotection, regeneration, and functional plasticity in the adult brain. ScientificWorldJournal 6, 53-80.
    • (2006) Scientific World Journal , vol.6 , pp. 53-80
    • Aberg, N.D.1    Brywe, K.G.2    Isgaard, J.3
  • 3
    • 0023933146 scopus 로고
    • Differing expression of insulin-like growth factor i in the developing and in the adult rat cerebellum
    • Andersson, I.K., Edwall, D., Norstedt, G., Rozell, B., Skottner, A., and Hansson, H.A. (1988). Differing expression of insulin-like growth factor I in the developing and in the adult rat cerebellum. Acta Physiol. Scand. 132, 167-173.
    • (1988) Acta Physiol. Scand. , vol.132 , pp. 167-173
    • Andersson, I.K.1    Edwall, D.2    Norstedt, G.3    Rozell, B.4    Skottner, A.5    Hansson, H.A.6
  • 4
    • 0025938153 scopus 로고
    • Localization of insulin-like growth factor-1 mRNA in murine central nervous system during postnatal development
    • Bartlett, W.P., Li, X.S., Williams, M., and Benkovic, S. (1991). Localization of insulin-like growth factor-1 mRNA in murine central nervous system during postnatal development. Dev. Biol. 147, 239-250.
    • (1991) Dev. Biol. , vol.147 , pp. 239-250
    • Bartlett, W.P.1    Li, X.S.2    Williams, M.3    Benkovic, S.4
  • 6
    • 0027272556 scopus 로고
    • Changes in insulin-like growth factor 1 receptor density after transient cerebral ischemia in the rat. Lack of protection against ischemic brain damage following injection of insulin-like growth factor 1
    • Bergstedt, K., and Wieloch, T. (1993). Changes in insulin-like growth factor 1 receptor density after transient cerebral ischemia in the rat. Lack of protection against ischemic brain damage following injection of insulin-like growth factor 1. J. Cereb. Blood Flow Metab. 13, 895-898.
    • (1993) J. Cereb. Blood Flow Metab. , vol.13 , pp. 895-898
    • Bergstedt, K.1    Wieloch, T.2
  • 7
    • 0026556829 scopus 로고
    • Cellular pattern of type-I insulin-like growth factor receptor gene expression during maturation of the rat brain: Comparison with insulin-like growth factors i and II
    • Bondy, C., Werner, H., Roberts, C.T., Jr., and LeRoith, D. (1992). Cellular pattern of type-I insulin-like growth factor receptor gene expression during maturation of the rat brain: comparison with insulin-like growth factors I and II. Neuroscience 46, 909-923.
    • (1992) Neuroscience , vol.46 , pp. 909-923
    • Bondy, C.1    Werner, H.2    Roberts Jr., C.T.3    Le Roith, D.4
  • 9
    • 0029160069 scopus 로고
    • Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
    • Burgering, B.M., and Coffer, P.J. (1995). Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376, 599-602.
    • (1995) Nature , vol.376 , pp. 599-602
    • Burgering, B.M.1    Coffer, P.J.2
  • 10
    • 0038119611 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF)-1 suppresses oligodendrocyte caspase-3 activation and increases glial proliferation after ischemia in near-term fetal sheep
    • Cao, Y., Gunn, A.J., Bennet, L., Wu, D., George, S., Gluckman, P.D., Shao, X.M., and Guan, J. (2003). Insulin-like growth factor (IGF)-1 suppresses oligodendrocyte caspase-3 activation and increases glial proliferation after ischemia in near-term fetal sheep. J. Cereb. Blood Flow Metab. 23, 739-747.
    • (2003) J. Cereb. Blood Flow Metab. , vol.23 , pp. 739-747
    • Cao, Y.1    Gunn, A.J.2    Bennet, L.3    Wu, D.4    George, S.5    Gluckman, P.D.6    Shao, X.M.7    Guan, J.8
  • 11
    • 2442711785 scopus 로고    scopus 로고
    • Insulin-like growth factor i receptors are more abundant than insulin receptors in human micro-and macrovascular endothelial cells
    • Chisalita, S.I., and Arnqvist, H.J. (2004). Insulin-like growth factor I receptors are more abundant than insulin receptors in human micro-and macrovascular endothelial cells. Am. J. Physiol. 286, E896-E901.
    • (2004) Am. J. Physiol. , vol.286
    • Chisalita, S.I.1    Arnqvist, H.J.2
  • 12
    • 0032834555 scopus 로고    scopus 로고
    • Hypoxia-ischemia-induced apoptotic cell death correlates with IGF-I mRNA decrease in neonatal rat brain
    • Clawson, T.F., Vannucci, S.J., Wang, G.M., Seaman, L.B., Yang, X.L., and Lee, W.H. (1999). Hypoxia-ischemia-induced apoptotic cell death correlates with IGF-I mRNA decrease in neonatal rat brain. Biol. Signals Recept. 8, 281-293.
    • (1999) Biol. Signals Recept. , vol.8 , pp. 281-293
    • Clawson, T.F.1    Vannucci, S.J.2    Wang, G.M.3    Seaman, L.B.4    Yang, X.L.5    Lee, W.H.6
  • 14
    • 0030330547 scopus 로고    scopus 로고
    • The role of the insulin-like growth factors in the central nervous system
    • D'Ercole, A.J., Ye, P., Calikoglu, A.S., and Gutierrez-Ospina, G. (1996). The role of the insulin-like growth factors in the central nervous system. Mol. Neurobiol. 13, 227-255.
    • (1996) Mol. Neurobiol. , vol.13 , pp. 227-255
    • D'Ercole, A.J.1    Ye, P.2    Calikoglu, A.S.3    Gutierrez-Ospina, G.4
  • 16
    • 43449094629 scopus 로고    scopus 로고
    • Mild traumatic brain injury to the infant mouse causes robust white matter axonal degeneration which precedes apoptotic death of cortical and thalamic neurons
    • Dikranian, K., Cohen, R., Mac Donald, C., Pan, Y., Brakefield, D., Bayly, P., and Parsadanian, A. (2008). Mild traumatic brain injury to the infant mouse causes robust white matter axonal degeneration which precedes apoptotic death of cortical and thalamic neurons. Exp. Neurol. 211, 551-560.
    • (2008) Exp. Neurol. , vol.211 , pp. 551-560
    • Dikranian, K.1    Cohen, R.2    Mac Donald, C.3    Pan, Y.4    Brakefield, D.5    Bayly, P.6    Parsadanian, A.7
  • 17
    • 0345731381 scopus 로고    scopus 로고
    • Plasticity following injury to the adult central nervous system: Is recapitulation of a developmental state worth promoting?
    • Emery, D.L., Royo, N.C., Fischer, I., Saatman, K.E., and McIntosh, T.K. (2003). Plasticity following injury to the adult central nervous system: is recapitulation of a developmental state worth promoting? J. Neurotrauma 20, 1271-1292.
    • (2003) J. Neurotrauma , vol.20 , pp. 1271-1292
    • Emery, D.L.1    Royo, N.C.2    Fischer, I.3    Saatman, K.E.4    McIntosh, T.K.5
  • 18
    • 0029079275 scopus 로고
    • The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
    • Franke, T.F., Yang, S.I., Chan, T.O., Datta, K., Kazlauskas, A., Morrison, D.K., Kaplan, D.R., and Tsichlis, P.N. (1995). The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 81, 727-736.
    • (1995) Cell , vol.81 , pp. 727-736
    • Franke, T.F.1    Yang, S.I.2    Chan, T.O.3    Datta, K.4    Kazlauskas, A.5    Morrison, D.K.6    Kaplan, D.R.7    Tsichlis, P.N.8
  • 19
    • 0026700490 scopus 로고
    • Expression of insulin-like growth factor i by astrocytes in response to injury
    • Garcia-Estrada, J., Garcia-Segura, L.M., and Torres-Aleman, I. (1992). Expression of insulin-like growth factor I by astrocytes in response to injury. Brain Res. 592, 343-347.
    • (1992) Brain Res. , vol.592 , pp. 343-347
    • Garcia-Estrada, J.1    Garcia-Segura, L.M.2    Torres-Aleman, I.3
  • 21
    • 0033988001 scopus 로고    scopus 로고
    • Intracerebral transportation and cellular localisation of insulin-like growth factor-1 following central administration to rats with hypoxic-ischemic brain injury
    • Guan, J., Beilharz, E.J., Skinner, S.J., Williams, C.E., and Gluckman, P.D. (2000). Intracerebral transportation and cellular localisation of insulin-like growth factor-1 following central administration to rats with hypoxic-ischemic brain injury. Brain Res. 853, 163-173.
    • (2000) Brain Res. , vol.853 , pp. 163-173
    • Guan, J.1    Beilharz, E.J.2    Skinner, S.J.3    Williams, C.E.4    Gluckman, P.D.5
  • 22
    • 0141956456 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 and post-ischemic brain injury
    • Guan, J., Bennet, L., Gluckman, P.D., and Gunn, A.J. (2003). Insulin-like growth factor-1 and post-ischemic brain injury. Prog. Neurobiol. 70, 443-462.
    • (2003) Prog. Neurobiol. , vol.70 , pp. 443-462
    • Guan, J.1    Bennet, L.2    Gluckman, P.D.3    Gunn, A.J.4
  • 23
    • 0035958653 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 improves somatosensory function and reduces the extent of cortical infarction and ongoing neuronal loss after hypoxia-ischemia in rats
    • Guan, J., Miller, O.T., Waugh, K.M., McCarthy, D.C., and Gluckman, P.D. (2001). Insulin-like growth factor-1 improves somatosensory function and reduces the extent of cortical infarction and ongoing neuronal loss after hypoxia-ischemia in rats. Neuroscience 105, 299-306.
    • (2001) Neuroscience , vol.105 , pp. 299-306
    • Guan, J.1    Miller, O.T.2    Waugh, K.M.3    McCarthy, D.C.4    Gluckman, P.D.5
  • 25
    • 0032763662 scopus 로고    scopus 로고
    • Mild experimental brain injury differentially alters the expression of neurotrophin and neurotrophin receptor mRNAs in the hippocampus
    • Hicks, R.R., Martin, V.B., Zhang, L., and Seroogy, K.B. (1999). Mild experimental brain injury differentially alters the expression of neurotrophin and neurotrophin receptor mRNAs in the hippocampus. Exp. Neurol. 160, 469-478.
    • (1999) Exp. Neurol. , vol.160 , pp. 469-478
    • Hicks, R.R.1    Martin, V.B.2    Zhang, L.3    Seroogy, K.B.4
  • 26
    • 57449092483 scopus 로고    scopus 로고
    • IGF-I gene delivery promotes corticospinal neuronal survival but not regeneration after adult CNS injury
    • Hollis, E.R., 2nd, Lu, P., Blesch, A., and Tuszynski, M.H. (2009). IGF-I gene delivery promotes corticospinal neuronal survival but not regeneration after adult CNS injury. Exp. Neurol. 215, 53-59.
    • (2009) Exp. Neurol. , vol.215 , pp. 53-59
    • Hollis II, E.R.1    Lu, P.2    Blesch, A.3    Tuszynski, M.H.4
  • 27
    • 33847043605 scopus 로고    scopus 로고
    • Gene transfer of insulin-like growth factor-I providing neuroprotection after spinal cord injury in rats
    • Hung, K.S., Tsai, S.H., Lee, T.C., Lin, J.W., Chang, C.K., and Chiu, W.T. (2007). Gene transfer of insulin-like growth factor-I providing neuroprotection after spinal cord injury in rats. J. Neurosurg. Spine 6, 35-46.
    • (2007) J. Neurosurg. Spine , vol.6 , pp. 35-46
    • Hung, K.S.1    Tsai, S.H.2    Lee, T.C.3    Lin, J.W.4    Chang, C.K.5    Chiu, W.T.6
  • 28
    • 11144356364 scopus 로고    scopus 로고
    • Expression and changes of endogenous insulin-like growth factor-1 in neurons and glia in the gerbil hippocampus and dentate gyrus after ischemic insult
    • Hwang, I.K., Yoo, K.Y., Park, S.K., An, S.J., Lee, J.Y., Choi, S.Y., Kang, J.H., Kwon, Y.G., Kang, T.C., and Won, M.H. (2004). Expression and changes of endogenous insulin-like growth factor-1 in neurons and glia in the gerbil hippocampus and dentate gyrus after ischemic insult. Neurochem. Int. 45, 149-156.
    • (2004) Neurochem. Int. , vol.45 , pp. 149-156
    • Hwang, I.K.1    Yoo, K.Y.2    Park, S.K.3    An, S.J.4    Lee, J.Y.5    Choi, S.Y.6    Kang, J.H.7    Kwon, Y.G.8    Kang, T.C.9    Won, M.H.10
  • 29
    • 0034745642 scopus 로고    scopus 로고
    • Alterations of Akt1 (PKBalpha) and p70(S6K) in transient focal ischemia
    • Janelidze, S., Hu, B.R., Siesjo, P., and Siesjo, B.K. (2001). Alterations of Akt1 (PKBalpha) and p70(S6K) in transient focal ischemia. Neurobiol. Dis. 8, 147-154.
    • (2001) Neurobiol. Dis. , vol.8 , pp. 147-154
    • Janelidze, S.1    Hu, B.R.2    Siesjo, P.3    Siesjo, B.K.4
  • 30
    • 0035205216 scopus 로고    scopus 로고
    • Neuroprotective effect of sodium orthovanadate on delayed neuronal death after transient forebrain ischemia in gerbil hippocampus
    • Kawano, T., Fukunaga, K., Takeuchi, Y., Morioka, M., Yano, S., Hamada, J., Ushio, Y., and Miyamoto, E. (2001). Neuroprotective effect of sodium orthovanadate on delayed neuronal death after transient forebrain ischemia in gerbil hippocampus. J. Cereb. Blood Flow Metab. 21, 1268-1280.
    • (2001) J. Cereb. Blood Flow Metab. , vol.21 , pp. 1268-1280
    • Kawano, T.1    Fukunaga, K.2    Takeuchi, Y.3    Morioka, M.4    Yano, S.5    Hamada, J.6    Ushio, Y.7    Miyamoto, E.8
  • 31
    • 1542722935 scopus 로고    scopus 로고
    • Alterations in IGF-I., BDNF and NT-3 levels following experimental brain trauma and the effect of IGF-I administration
    • Kazanis, I., Giannakopoulou, M., Philippidis, H., and Stylianopoulou, F. (2004). Alterations in IGF-I., BDNF and NT-3 levels following experimental brain trauma and the effect of IGF-I administration. Exp. Neurol. 186, 221-234.
    • (2004) Exp. Neurol. , vol.186 , pp. 221-234
    • Kazanis, I.1    Giannakopoulou, M.2    Philippidis, H.3    Stylianopoulou, F.4
  • 32
    • 9444237919 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase and Akt effectors mediate insulin-like growth factor-I neuroprotection in dorsal root ganglia neurons
    • Leinninger, G.M., Backus, C., Uhler, M.D., Lentz, S.I., and Feldman, E.L. (2004). Phosphatidylinositol 3-kinase and Akt effectors mediate insulin-like growth factor-I neuroprotection in dorsal root ganglia neurons. FASEB J. 18, 1544-1546.
    • (2004) FASEB J. , vol.18 , pp. 1544-1546
    • Leinninger, G.M.1    Backus, C.2    Uhler, M.D.3    Lentz, S.I.4    Feldman, E.L.5
  • 33
    • 0035800541 scopus 로고    scopus 로고
    • Non-invasive intranasal insulin-like growth factor-I reduces infarct volume and improves neurologic function in rats following middle cerebral artery occlusion
    • Liu, X.F., Fawcett, J.R., Thorne, R.G., and Frey, W.H. (2001). Non-invasive intranasal insulin-like growth factor-I reduces infarct volume and improves neurologic function in rats following middle cerebral artery occlusion. Neurosci. Lett. 308, 91-94.
    • (2001) Neurosci. Lett. , vol.308 , pp. 91-94
    • Liu, X.F.1    Fawcett, J.R.2    Thorne, R.G.3    Frey, W.H.4
  • 34
    • 0031894808 scopus 로고    scopus 로고
    • Cerebral interleukin-6 is neuroprotective during permanent focal cerebral ischemia in the rat
    • Loddick, S.A., Turnbull, A.V., and Rothwell, N.J. (1998). Cerebral interleukin-6 is neuroprotective during permanent focal cerebral ischemia in the rat. J. Cereb. Blood Flow Metab. 18, 176-179.
    • (1998) J. Cereb. Blood Flow Metab. , vol.18 , pp. 176-179
    • Loddick, S.A.1    Turnbull, A.V.2    Rothwell, N.J.3
  • 35
    • 34547581940 scopus 로고    scopus 로고
    • Neovascularization following traumatic brain injury: Possible evidence for both angiogenesis and vasculogenesis
    • Morgan, R., Kreipke, C.W., Roberts, G., Bagchi, M., and Rafols, J.A. (2007). Neovascularization following traumatic brain injury: possible evidence for both angiogenesis and vasculogenesis. Neurol. Res. 29, 375-381.
    • (2007) Neurol. Res. , vol.29 , pp. 375-381
    • Morgan, R.1    Kreipke, C.W.2    Roberts, G.3    Bagchi, M.4    Rafols, J.A.5
  • 36
    • 0035412840 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 prevents neuronal cell death and paraplegia in the rabbit model of spinal cord ischemia
    • Nakao, Y., Otani, H., Yamamura, T., Hattori, R., Osako, M., and Imamura, H. (2001). Insulin-like growth factor 1 prevents neuronal cell death and paraplegia in the rabbit model of spinal cord ischemia. J. Thorac. Cardiovasc. Surg. 122, 136-143.
    • (2001) J. Thorac. Cardiovasc. Surg. , vol.122 , pp. 136-143
    • Nakao, Y.1    Otani, H.2    Yamamura, T.3    Hattori, R.4    Osako, M.5    Imamura, H.6
  • 37
    • 0033849407 scopus 로고    scopus 로고
    • Serine-threonine protein kinase Akt does not mediate ischemic tolerance after global ischemia in the gerbil
    • Namura, S., Nagata, I., Kikuchi, H., Andreucci, M., and Alessandrini, A. (2000). Serine-threonine protein kinase Akt does not mediate ischemic tolerance after global ischemia in the gerbil. J. Cereb. Blood Flow Metab. 20, 1301-1305.
    • (2000) J. Cereb. Blood Flow Metab. , vol.20 , pp. 1301-1305
    • Namura, S.1    Nagata, I.2    Kikuchi, H.3    Andreucci, M.4    Alessandrini, A.5
  • 38
    • 0034213719 scopus 로고    scopus 로고
    • Insulin-like growth factor i stimulates dendritic growth in primary somatosensory cortex
    • Niblock, M.M., Brunso-Bechtold, J.K., and Riddle, D.R. (2000). Insulin-like growth factor I stimulates dendritic growth in primary somatosensory cortex. J. Neurosci. 20, 4165-4176.
    • (2000) J. Neurosci. , vol.20 , pp. 4165-4176
    • Niblock, M.M.1    Brunso-Bechtold, J.K.2    Riddle, D.R.3
  • 39
    • 0027526550 scopus 로고
    • Regional changes in interstitial Kp and Ca2p levels following cortical compression contusion trauma in rats
    • Nilsson, P., Hillered, L., Olsson, Y., Sheardown, M.J., and Hansen, A.J. (1993). Regional changes in interstitial Kp and Ca2p levels following cortical compression contusion trauma in rats. J. Cereb. Blood Flow Metab. 13, 183-192.
    • (1993) J. Cereb. Blood Flow Metab. , vol.13 , pp. 183-192
    • Nilsson, P.1    Hillered, L.2    Olsson, Y.3    Sheardown, M.J.4    Hansen, A.J.5
  • 40
    • 0030047543 scopus 로고    scopus 로고
    • Calcium movements in traumatic brain injury: The role of glutamate receptor-operated ion channels
    • Nilsson, P., Laursen, H., Hillered, L., and Hansen, A.J. (1996). Calcium movements in traumatic brain injury: the role of glutamate receptor-operated ion channels. J. Cereb. Blood Flow Metab. 16, 262-270.
    • (1996) J. Cereb. Blood Flow Metab. , vol.16 , pp. 262-270
    • Nilsson, P.1    Laursen, H.2    Hillered, L.3    Hansen, A.J.4
  • 41
    • 0036237137 scopus 로고    scopus 로고
    • Akt phosphorylation and neuronal survival after traumatic brain injury in mice
    • Noshita, N., Lewen, A., Sugawara, T., and Chan, P.H. (2002). Akt phosphorylation and neuronal survival after traumatic brain injury in mice. Neurobiol. Dis. 9, 294-304.
    • (2002) Neurobiol. Dis. , vol.9 , pp. 294-304
    • Noshita, N.1    Lewen, A.2    Sugawara, T.3    Chan, P.H.4
  • 42
    • 0033812270 scopus 로고    scopus 로고
    • Molecular mechanisms regulating the retrograde axonal transport of neurotrophins
    • Reynolds, A.J., Bartlett, S.E., and Hendry, I.A. (2000). Molecular mechanisms regulating the retrograde axonal transport of neurotrophins. Brain Res. Brain Res. Rev. 33, 169-178.
    • (2000) Brain Res. Brain Res. Rev. , vol.33 , pp. 169-178
    • Reynolds, A.J.1    Bartlett, S.E.2    Hendry, I.A.3
  • 43
    • 34547960588 scopus 로고    scopus 로고
    • Insulin-like growth factor type-I receptor internalization and recycling mediate the sustained phosphorylation of Akt
    • Romanelli, R.J., LeBeau, A.P., Fulmer, C.G., Lazzarino, D.A., Hochberg, A., and Wood, T.L. (2007). Insulin-like growth factor type-I receptor internalization and recycling mediate the sustained phosphorylation of Akt. J. Biol. Chem. 282, 22513-22524.
    • (2007) J. Biol. Chem. , vol.282 , pp. 22513-22524
    • Romanelli, R.J.1    Le Beau, A.P.2    Fulmer, C.G.3    Lazzarino, D.A.4    Hochberg, A.5    Wood, T.L.6
  • 44
    • 0011016769 scopus 로고
    • Differential expression of insulin-like growth factor genes in rat central nervous system
    • Rotwein, P., Burgess, S.K., Milbrandt, J.D., and Krause, J.E. (1988). Differential expression of insulin-like growth factor genes in rat central nervous system. Proc. Natl. Acad. Sci. U.S.A. 85, 265-269.
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 265-269
    • Rotwein, P.1    Burgess, S.K.2    Milbrandt, J.D.3    Krause, J.E.4
  • 46
    • 0037215483 scopus 로고    scopus 로고
    • Traumatic axonal injury results in biphasic calpain activation and retrograde transport impairment in mice
    • Saatman, K.E., Abai, B., Grosvenor, A., Vorwerk, C.K., Smith, D.H., and Meaney, D.F. (2003). Traumatic axonal injury results in biphasic calpain activation and retrograde transport impairment in mice. J. Cereb. Blood Flow Metab. 23, 34-42.
    • (2003) J. Cereb. Blood Flow Metab. , vol.23 , pp. 34-42
    • Saatman, K.E.1    Abai, B.2    Grosvenor, A.3    Vorwerk, C.K.4    Smith, D.H.5    Meaney, D.F.6
  • 48
    • 33750127952 scopus 로고    scopus 로고
    • Differential behavioral and histopathological responses to graded cortical impact injury inmice
    • Saatman, K.E., Feeko, K.J., Pape, R.L., and Raghupathi, R. (2006). Differential behavioral and histopathological responses to graded cortical impact injury inmice. J. Neurotrauma 23, 1241-1253.
    • (2006) J. Neurotrauma , vol.23 , pp. 1241-1253
    • Saatman, K.E.1    Feeko, K.J.2    Pape, R.L.3    Raghupathi, R.4
  • 50
    • 0027968141 scopus 로고
    • Direct measurement of hydroxyl radicals, lipid peroxidation, and blood-brain barrier disruption following unilateral cortical impact head injury in the rat
    • Smith, S.L., Andrus, P.K., Zhang, J.R., and Hall, E.D. (1994). Direct measurement of hydroxyl radicals, lipid peroxidation, and blood-brain barrier disruption following unilateral cortical impact head injury in the rat. J. Neurotrauma 11, 393-404.
    • (1994) J. Neurotrauma , vol.11 , pp. 393-404
    • Smith, S.L.1    Andrus, P.K.2    Zhang, J.R.3    Hall, E.D.4
  • 51
    • 0035283153 scopus 로고    scopus 로고
    • Circulating insulin-like growth factor i mediates exercise-induced increases in the number of new neurons in the adult hippocampus
    • Trejo, J.L., Carro, E., and Torres-Aleman, I. (2001). Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus. J. Neurosci. 21, 1628-1634.
    • (2001) J. Neurosci. , vol.21 , pp. 1628-1634
    • Trejo, J.L.1    Carro, E.2    Torres-Aleman, I.3
  • 52
    • 2942695980 scopus 로고    scopus 로고
    • IGF-I prevents glutamate-induced motor neuron programmed cell death
    • Vincent, A.M., Mobley, B.C., Hiller, A., and Feldman, E.L. (2004). IGF-I prevents glutamate-induced motor neuron programmed cell death. Neurobiol. Dis. 16, 407-416.
    • (2004) Neurobiol. Dis. , vol.16 , pp. 407-416
    • Vincent, A.M.1    Mobley, B.C.2    Hiller, A.3    Feldman, E.L.4
  • 53
    • 0030960382 scopus 로고    scopus 로고
    • Spatial and temporal changes in the insulin-like growth factor (IGF) axis indicate autocrine=paracrine actions of IGF-I within wounds of the rat brain
    • Walter, H.J., Berry, M., Hill, D.J., and Logan, A. (1997). Spatial and temporal changes in the insulin-like growth factor (IGF) axis indicate autocrine=paracrine actions of IGF-I within wounds of the rat brain. Endocrinology 138, 3024-3034.
    • (1997) Endocrinology , vol.138 , pp. 3024-3034
    • Walter, H.J.1    Berry, M.2    Hill, D.J.3    Logan, A.4
  • 56
    • 0035864751 scopus 로고    scopus 로고
    • Post-traumatic changes in insulin-like growth factor type 1 and growth hormone in patients with bone fractures and traumatic brain injury
    • Wildburger, R., Zarkovic, N., Leb, G., Borovic, S., Zarkovic, K., and Tatzber, F. (2001). Post-traumatic changes in insulin-like growth factor type 1 and growth hormone in patients with bone fractures and traumatic brain injury. Wien. Klin. Wochenschr. 113, 119-126.
    • (2001) Wien. Klin. Wochenschr. , vol.113 , pp. 119-126
    • Wildburger, R.1    Zarkovic, N.2    Leb, G.3    Borovic, S.4    Zarkovic, K.5    Tatzber, F.6
  • 57
    • 0028791354 scopus 로고
    • Regional and temporal profiles of c-fos and nerve growth factor mRNA expression in rat brain after lateral cortical impact injury
    • Yang, K., Mu, X.S., Xue, J.J., Perez-Polo, J.R., and Hayes, R.L. (1995). Regional and temporal profiles of c-fos and nerve growth factor mRNA expression in rat brain after lateral cortical impact injury. J. Neurosci. Res. 42, 571-578.
    • (1995) J. Neurosci. Res. , vol.42 , pp. 571-578
    • Yang, K.1    Mu, X.S.2    Xue, J.J.3    Perez-Polo, J.R.4    Hayes, R.L.5
  • 58
    • 0029965072 scopus 로고    scopus 로고
    • Increased expression of brain-derived neurotrophic factor but not neurotrophin-3 mRNA in rat brain after cortical impact injury
    • Yang, K., Perez-Polo, J.R., Mu, X.S., Yan, H.Q., Xue, J.J., Iwamoto, Y., Liu, J.S., Dixon, C.E., and Hayes, R.L. (1996). Increased expression of brain-derived neurotrophic factor but not neurotrophin-3 mRNA in rat brain after cortical impact injury. J. Neurosci. Res. 44, 157-164.
    • (1996) J. Neurosci. Res. , vol.44 , pp. 157-164
    • Yang, K.1    Perez-Polo, J.R.2    Mu, X.S.3    Yan, H.Q.4    Xue, J.J.5    Iwamoto, Y.6    Liu, J.S.7    Dixon, C.E.8    Hayes, R.L.9
  • 59
    • 0035048206 scopus 로고    scopus 로고
    • Activation of Akt=protein kinase B contributes to induction of ischemic tolerance in the CA1 subfield of gerbil hippocampus
    • Yano, S., Morioka, M., Fukunaga, K., Kawano, T., Hara, T., Kai, Y., Hamada, J., Miyamoto, E., and Ushio, Y. (2001). Activation of Akt=protein kinase B contributes to induction of ischemic tolerance in the CA1 subfield of gerbil hippocampus. J. Cereb. Blood Flow Metab. 21, 351-360.
    • (2001) J. Cereb. Blood Flow Metab. , vol.21 , pp. 351-360
    • Yano, S.1    Morioka, M.2    Fukunaga, K.3    Kawano, T.4    Hara, T.5    Kai, Y.6    Hamada, J.7    Miyamoto, E.8    Ushio, Y.9
  • 60
    • 33846962851 scopus 로고    scopus 로고
    • Insulin-like growth factor type 1 receptor signaling in the cells of oligodendrocyte lineage is required for normal in vivo oligodendrocyte development and myelination
    • Zeger, M., Popken, G., Zhang, J., Xuan, S., Lu, Q.R., Schwab, M.H., Nave, K.A., Rowitch, D., D'Ercole, A.J., and Ye, P. (2007). Insulin-like growth factor type 1 receptor signaling in the cells of oligodendrocyte lineage is required for normal in vivo oligodendrocyte development and myelination. Glia 55, 400-411.
    • (2007) Glia , vol.55 , pp. 400-411
    • Zeger, M.1    Popken, G.2    Zhang, J.3    Xuan, S.4    Lu, Q.R.5    Schwab, M.H.6    Nave, K.A.7    Rowitch, D.8    D'Ercole, A.J.9    Ye, P.10
  • 62
    • 33847014888 scopus 로고    scopus 로고
    • Phosphoinositide-3-kinase=akt survival signal pathways are implicated in neuronal survival after stroke
    • Zhao, H., Sapolsky, R.M., and Steinberg, G.K. (2006). Phosphoinositide-3-kinase=akt survival signal pathways are implicated in neuronal survival after stroke. Mol. Neurobiol. 34, 249-270.
    • (2006) Mol. Neurobiol. , vol.34 , pp. 249-270
    • Zhao, H.1    Sapolsky, R.M.2    Steinberg, G.K.3
  • 63
    • 0034518163 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 (IGF-1): A neuroprotective trophic factor acting via the Akt kinase pathway
    • Zheng, W.H., Kar, S., Dore, S., and Quirion, R. (2000). Insulin-like growth factor-1 (IGF-1): a neuroprotective trophic factor acting via the Akt kinase pathway. J. Neural Transm. 261-272.
    • (2000) J. Neural Transm. , pp. 261-272
    • Zheng, W.H.1    Kar, S.2    Dore, S.3    Quirion, R.4


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