-
1
-
-
13544258096
-
The latency-associated nuclear antigen of Kaposi's sarcomaassociated herpesvirus modulates cellular gene expression and protects lymphoid cells from p16 INK4A-induced cell cycle arrest
-
An, F. Q., N. Compitello, E. Horwitz, M. Sramkoski, E. S. Knudsen, and R. Renne. 2005. The latency-associated nuclear antigen of Kaposi's sarcomaassociated herpesvirus modulates cellular gene expression and protects lymphoid cells from p16 INK4A-induced cell cycle arrest. J. Biol. Chem. 280: 3862-3874.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 3862-3874
-
-
An, F.Q.1
Compitello, N.2
Horwitz, E.3
Sramkoski, M.4
Knudsen, E.S.5
Renne, R.6
-
2
-
-
0033597453
-
Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigen
-
Ballestas, M. E., P. A. Chatis, and K. M. Kaye. 1999. Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigen. Science 284: 641-644.
-
(1999)
Science
, vol.284
, pp. 641-644
-
-
Ballestas, M.E.1
Chatis, P.A.2
Kaye, K.M.3
-
3
-
-
0035100879
-
Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 mediates episome persistence through cts-acting terminal repeat (TR) sequence and specifically binds TR
-
Ballestas, M. E., and K. M. Kaye. 2001. Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 mediates episome persistence through cts-acting terminal repeat (TR) sequence and specifically binds TR DNA. J. Virol. 75: 3250-3258.
-
(2001)
DNA. J. Virol.
, vol.75
, pp. 3250-3258
-
-
Ballestas, M.E.1
Kaye, K.M.2
-
4
-
-
32444439636
-
The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus
-
Barbera, A. J., J. V. Chodaparambil, B. Kelley-Clarke, V. Joukov, J. C. Walter, K. Luger, and K. M. Kaye. 2006. The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA. Science 311: 856-861.
-
(2006)
LANA. Science
, vol.311
, pp. 856-861
-
-
Barbera, A.J.1
Chodaparambil, J.V.2
Kelley-Clarke, B.3
Joukov, V.4
Walter, J.C.5
Luger, K.6
Kaye, K.M.7
-
5
-
-
0026686753
-
Sitespecific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53
-
Bargonetti, J., I. Reynisdottir, P. N. Friedman, and C. Prives. 1992. Sitespecific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53. Genes Dev. 6: 1886-1898.
-
(1992)
Genes Dev.
, vol.6
, pp. 1886-1898
-
-
Bargonetti, J.1
Reynisdottir, I.2
Friedman, P.N.3
Prives, C.4
-
6
-
-
0027321050
-
Hemi-or homozygosity: A requirement for some but not other p53 mutant proteins to accumulate and exert a pathogenetic effect
-
Bhatia, K., W. Goldschmidts, M. Gutierrez, G. Gaidano, R. Dalla-Favera, and I. Magrath. 1993. Hemi- or homozygosity: a requirement for some but not other p53 mutant proteins to accumulate and exert a pathogenetic effect. FASEB J. 7: 951-956.
-
(1993)
FASEB J.
, vol.7
, pp. 951-956
-
-
Bhatia, K.1
Goldschmidts, W.2
Gutierrez, M.3
Gaidano, G.R.4
Dalla-Favera5
Magrath, I.6
-
7
-
-
4544381676
-
ORF73 of herpesvirus saimiri, a viral homolog of Kaposi's sarcoma-associated herpesvirus, modulates the two cellular tumor suppressor proteins p53 and pRb
-
Borah, S., S. C. Verma, and E. S. Robertson. 2004. ORF73 of herpesvirus saimiri, a viral homolog of Kaposi's sarcoma-associated herpesvirus, modulates the two cellular tumor suppressor proteins p53 and pRb. J. Virol. 78: 10336-10347.
-
(2004)
J. Virol.
, vol.78
, pp. 10336-10347
-
-
Borah, S.1
Verma, S.C.2
Robertson, E.S.3
-
8
-
-
0034282102
-
An intact HDM2 RING-finger domain is required for nuclear exclusion of p53
-
Boyd, S. D., K. Y. Tsai, and T. Jacks. 2000. An intact HDM2 RING-finger domain is required for nuclear exclusion of p53. Nat. Cell Biol. 2: 563-568.
-
(2000)
Nat. Cell. Biol.
, vol.2
, pp. 563-568
-
-
Boyd, S.D.1
Tsai, K.Y.2
Jacks, T.3
-
9
-
-
0023187971
-
Mouse p53 inhibits SV40 origin-dependent DNA replication
-
Braithwaite, A. W., H. W. Sturzbecher, C. Addison, C. Palmer, K. Rudge, and J. R. Jenkins. 1987. Mouse p53 inhibits SV40 origin-dependent DNA replication. Nature 329: 458-160.
-
(1987)
Nature
, vol.329
, pp. 458-160
-
-
Braithwaite, A.W.1
Sturzbecher, H.W.2
Addison, C.3
Palmer, C.4
Rudge, K.5
Jenkins, J.R.6
-
10
-
-
33750464049
-
EC5S ubiquitin complex is recruited by KSHV latent antigen LANA for degradation of the VHL and p53 tumor suppressors
-
Cai, Q. L., J. S. Knight, S. C. Verma, P. Zald, and E. S. Robertson. 2006. EC5S ubiquitin complex is recruited by KSHV latent antigen LANA for degradation of the VHL and p53 tumor suppressors. PLoS Pathog. 2: e116.
-
(2006)
PLoS Pathog.
, vol.2
-
-
Cai, Q.L.1
Knight, J.S.2
Verma, S.C.3
Zald, P.4
Robertson, E.S.5
-
11
-
-
0842278331
-
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
-
Chipuk, J. E., T. Kuwana, L. Bouchier-Hayes, N. M. Droin, D. D. Newmeyer, M. Schuler, and D. R. Green. 2004. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 303: 1010-1014.
-
(2004)
Science
, vol.303
, pp. 1010-1014
-
-
Chipuk, J.E.1
Kuwana, T.2
Bouchier-Hayes, L.3
Droin, N.M.4
Newmeyer, D.D.5
Schuler, M.6
Green, D.R.7
-
12
-
-
0344925540
-
Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription
-
Chipuk, J. E., U. Maurer, D. R. Green, and M. Schuler. 2003. Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription. Cancer Cell 4: 371-381.
-
(2003)
Cancer Cell.
, vol.4
, pp. 371-381
-
-
Chipuk, J.E.1
Maurer, U.2
Green, D.R.3
Schuler, M.4
-
13
-
-
0033604613
-
The latency-associated nuclear antigen tethers the Kaposi's sarcoma-associated herpesvirus genome to host chromosomes in body cavity-based lymphoma cells
-
Cotter, M. A., II, and E. S. Robertson. 1999. The latency-associated nuclear antigen tethers the Kaposi's sarcoma-associated herpesvirus genome to host chromosomes in body cavity-based lymphoma cells. Virology 264: 254-264.
-
(1999)
Virology
, vol.264
, pp. 254-264
-
-
Cotter, M.A.I.I.1
Robertson, E.S.2
-
14
-
-
0032546326
-
A transforming p53 mutant, which binds DNA, transactivates and induces apoptosis reveals a nuclear:cytoplasmic shuttling defect
-
Crook, T., G. A. Parker, M. Rozycka, S. Crossland, and M. J. Allday. 1998. A transforming p53 mutant, which binds DNA, transactivates and induces apoptosis reveals a nuclear:cytoplasmic shuttling defect. Oncogene 16: 1429-1441.
-
(1998)
Oncogene
, vol.16
, pp. 1429-1441
-
-
Crook, T.1
Parker, G.A.2
Rozycka, M.3
Crossland, S.4
Allday, M.J.5
-
15
-
-
84919981117
-
-
Damania, B., and J. B. Pipas ed., Springer, New York, NY
-
Damania, B., and J. B. Pipas (ed.). 2009. DNA tumor viruses. Springer, New York, NY.
-
(2009)
DNA Tumor Viruses
-
-
-
16
-
-
0021100690
-
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
-
Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11: 1475-1489.
-
(1983)
Nucleic Acids Res.
, vol.11
, pp. 1475-1489
-
-
Dignam, J.D.1
Lebovitz, R.M.2
Roeder, R.G.3
-
17
-
-
0027210981
-
Gain of function mutations in p53
-
Dittmer, D., S. Pati, G. Zambetti, S. Chu, A. K. Teresky, M. Moore, C. Finlay, and A. J. Levine. 1993. Gain of function mutations in p53. Nat. Genet. 4: 42-46.
-
(1993)
Nat. Genet.
, vol.4
, pp. 42-46
-
-
Dittmer, D.1
Pati, S.2
Zambetti, G.3
Chu, S.4
Teresky, A.K.5
Moore, M.6
Finlay, C.7
Levine, A.J.8
-
18
-
-
0033386807
-
Experimental transmission of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) to SCID-hu Thy /Liv mice
-
Dittmer, D., C. Stoddart, R. Renne, V. Linquist-Stepps, M. E. Moreno, C. Bare, J. M. McCune, and D. Ganem. 1999. Experimental transmission of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) to SCID-hu Thy /Liv mice. J. Exp. Med. 190: 1857-1868.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1857-1868
-
-
Dittmer, D.1
Stoddart, C.2
Renne, R.3
Linquist-Stepps, V.4
Moreno, M.E.5
Bare, C.6
McCune, J.M.7
Ganem, D.8
-
19
-
-
34548436128
-
Targeted therapy for Kaposi's sarcoma and Kaposi's sarcoma-associated herpesvirus
-
Dittmer, D. P., and S. E. Krown. 2007. Targeted therapy for Kaposi's sarcoma and Kaposi's sarcoma-associated herpesvirus. Curr. Opin. Oncol. 19: 452-457.
-
(2007)
Curr. Opin. Oncol
, vol.19
, pp. 452-457
-
-
Dittmer, D.P.1
Krown, S.E.2
-
20
-
-
0021058853
-
The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter
-
Dynan, W. S., and R. Tjian. 1983. The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter. Cell 35: 79-87.
-
(1983)
Cell.
, vol.35
, pp. 79-87
-
-
Dynan, W.S.1
Tjian, R.2
-
21
-
-
33644651607
-
The latency-associated nuclear antigen of Kaposi sarcoma-associated herpesvirus induces B cell hyperplasia and lymphoma
-
Fakhari, F. D., J. H. Jeong, Y. Kanan, and D. P. Dittmer. 2006. The latency-associated nuclear antigen of Kaposi sarcoma-associated herpesvirus induces B cell hyperplasia and lymphoma. J. Clin. Invest. 116: 735-742.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 735-742
-
-
Fakhari, F.D.1
Jeong, J.H.2
Kanan, Y.3
Dittmer, D.P.4
-
22
-
-
0034708458
-
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
-
Fang, S., J. P. Jensen, R. L. Ludwig, K. H. Vousden, and A. M. Weissman. 2000. Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53. J. Biol. Chem. 275: 8945-8951.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 8945-8951
-
-
Fang, S.1
Jensen, J.P.2
Ludwig, R.L.3
Vousden, K.H.4
Weissman, A.M.5
-
23
-
-
0033599006
-
P53 inhibition by the LANA protein of KSHV protects against cell death
-
Friborg, J., Jr., W. Kong, M. O. Hottiger, and G. J. Nabel. 1999. p53 inhibition by the LANA protein of KSHV protects against cell death. Nature 402: 889-894.
-
(1999)
Nature
, vol.402
, pp. 889-894
-
-
Friborg Jr., J.1
Kong, W.2
Hottiger, M.O.3
Nabel, G.J.4
-
24
-
-
0037348372
-
A novel viral mechanism for dysregulation of beta-catenin in Kaposi's sarcoma-associated herpesvirus latency
-
Fujimuro, M., F. Y. Wu, C. ApRhys, H. Kajumbula, D. B. Young, G. S. Hayward, and S. D. Hayward. 2003. A novel viral mechanism for dysregulation of beta-catenin in Kaposi's sarcoma-associated herpesvirus latency. Nat. Med. 9: 300-306.
-
(2003)
Nat. Med.
, vol.9
, pp. 300-306
-
-
Fujimuro, M.1
Wu, F.Y.2
ApRhys, C.3
Kajumbula, H.4
Young, D.B.5
Hayward, G.S.6
Hayward, S.D.7
-
25
-
-
0023260905
-
P53 and DNA polymerase alpha compete for binding to SV40 T antigen
-
Gannon, J. V., and D. P. Lane. 1987. p53 and DNA polymerase alpha compete for binding to SV40 T antigen. Nature 329: 456-458.
-
(1987)
Nature
, vol.329
, pp. 456-458
-
-
Gannon, J.V.1
Lane, D.P.2
-
26
-
-
0037178856
-
Atency-associated nuclear antigen (LANA) cooperatively binds to two sites within the terminal repeat, and both sites contribute to the ability of LANA to suppress transcription and to facilitate DNA replication
-
Garber, A. C., J. Hu, and R. Renne. 2002. atency-associated nuclear antigen (LANA) cooperatively binds to two sites within the terminal repeat, and both sites contribute to the ability of LANA to suppress transcription and to facilitate DNA replication. J. Biol. Chem. 277: 27401-27411.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 27401-27411
-
-
Garber, A.C.1
Hu, J.2
Renne, R.3
-
27
-
-
0034870212
-
DNA binding and modulation of gene expression by the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus
-
Garber, A. C., M. A. Shu, J. Hu, and R. Renne. 2001. DNA binding and modulation of gene expression by the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus. J. Virol. 75: 7882-7892.
-
(2001)
J. Virol.
, vol.75
, pp. 7882-7892
-
-
Garber, A.C.1
Shu, M.A.2
Hu, J.3
Renne, R.4
-
28
-
-
15244363671
-
Inhibiting primary effusion lymphoma by lentiviral vectors encoding short hairpin RNA
-
Godfrey, A., J. Anderson, A. Papanastasiou, Y. Takeuchi, and C. Boshoff. 2005. Inhibiting primary effusion lymphoma by lentiviral vectors encoding short hairpin RNA. Blood 105: 2510-2518.
-
(2005)
Blood
, vol.105
, pp. 2510-2518
-
-
Godfrey, A.1
Anderson, J.2
Papanastasiou, A.3
Takeuchi, Y.4
Boshoff, C.5
-
29
-
-
0034843974
-
The latency-associated nuclear antigen encoded by Kaposi's sarcoma-associated herpesvirus activates two major essential Epstein-Barr virus latent promoters
-
Groves, A. K., M. A. Cotter, C. Subramanian, and E. S. Robertson. 2001. The latency-associated nuclear antigen encoded by Kaposi's sarcoma-associated herpesvirus activates two major essential Epstein-Barr virus latent promoters. J. Virol. 75: 9446-9457.
-
(2001)
J. Virol.
, vol.75
, pp. 9446-9457
-
-
Groves, A.K.1
Cotter, M.A.2
Subramanian, C.3
Robertson, E.S.4
-
30
-
-
18344377030
-
The p53 pathway: Positive and negative feedback loops
-
Harris, S. L., and A. J. Levine. 2005. The p53 pathway: positive and negative feedback loops. Oncogene 24: 2899-2908.
-
(2005)
Oncogene
, vol.24
, pp. 2899-2908
-
-
Harris, S.L.1
Levine, A.J.2
-
31
-
-
0026303190
-
P53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts
-
Harvey, D. M., and A. J. Levine. 1991. p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts. Genes Dev. 5: 2375-2385.
-
(1991)
Genes Dev.
, vol.5
, pp. 2375-2385
-
-
Harvey, D.M.1
Levine, A.J.2
-
32
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt, Y., R. Maya, A. Kazaz, and M. Oren. 1997. Mdm2 promotes the rapid degradation of p53. Nature 387: 296-299.
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
33
-
-
0025894713
-
P53 mutations in human cancers
-
Hollstein, M., D. Sidransky, B. Vogelstein, and C. C. Harris. 1991. p53 mutations in human cancers. Science 253: 49-53.
-
(1991)
Science
, vol.253
, pp. 49-53
-
-
Hollstein, M.1
Sidransky, D.2
Vogelstein, B.3
Harris, C.C.4
-
34
-
-
0034624678
-
Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase
-
Honda, R., and H. Yasuda. 2000. Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase. Oncogene 19: 1473-1476.
-
(2000)
Oncogene
, vol.19
, pp. 1473-1476
-
-
Honda, R.1
Yasuda, H.2
-
35
-
-
0034881511
-
Latency-associated nuclear antigen encoded by Kaposi's sarcoma-associated herpesvirus interacts with tat and activates the long terminal repeat of human immunodeficiency virus type 1 in human cells
-
Hyun, T. S., C. Subramanian, M. A. Cotter II, R. A. Thomas, and E. S. Robertson. 2001. Latency-associated nuclear antigen encoded by Kaposi's sarcoma-associated herpesvirus interacts with tat and activates the long terminal repeat of human immunodeficiency virus type 1 in human cells. J. Virol. 75: 8761-8771.
-
(2001)
J. Virol.
, vol.75
, pp. 8761-8771
-
-
Hyun, T.S.1
Subramanian, C.2
Cotter, M.A.I.I.3
Thomas, R.A.4
Robertson, E.S.5
-
36
-
-
0026504287
-
Stability of p53 protein in rat cells transformed by various viral transforming genes
-
Inoue, H., G. Kondoh, T. M. Sudiro, and A. Hakura. 1992. Stability of p53 protein in rat cells transformed by various viral transforming genes. Virology 187: 343-347.
-
(1992)
Virology
, vol.187
, pp. 343-347
-
-
Inoue, H.1
Kondoh, G.2
Sudiro, T.M.3
Hakura, A.4
-
37
-
-
0033963335
-
MdmX protects p53 from Mdm2-mediated degradation
-
Jackson, M. W., and S. J. Berberich. 2000. MdmX protects p53 from Mdm2-mediated degradation. Mol. Cell. Biol. 20: 1001-1007.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1001-1007
-
-
Jackson, M.W.1
Berberich, S.J.2
-
38
-
-
0035132838
-
Differential regulation of the overlapping Kaposi's sarcoma-associated herpesvirus vGCR (orf74) and LANA (orf73) promoters
-
Jeong, J., J. Papin, and D. Dittmer. 2001. Differential regulation of the overlapping Kaposi's sarcoma-associated herpesvirus vGCR (orf74) and LANA (orf73) promoters. J. Virol. 75: 1798-1807.
-
(2001)
J. Virol.
, vol.75
, pp. 1798-1807
-
-
Jeong, J.1
Papin, J.2
Dittmer, D.3
-
39
-
-
1942501536
-
Regulation and autoregulation of the promoter for the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus
-
Jeong, J. H., J. Orvis, J. W. Kim, C. P. McMurtrey, R. Renne, and D. P. Dittmer. 2004. Regulation and autoregulation of the promoter for the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus. J. Biol. Chem. 279: 16822-16831.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 16822-16831
-
-
Jeong, J.H.1
Orvis, J.2
Kim, J.W.3
McMurtrey, C.P.4
Renne, R.5
Dittmer, D.P.6
-
40
-
-
0035892769
-
Expression of p53 and human herpesvirus-8 (HHV-8)-encoded latency-associated nuclear antigen with inhibition of apoptosis in HHV-8-associated malignancies
-
Katano, H., Y. Sato, and T. Sata. 2001. Expression of p53 and human herpesvirus-8 (HHV-8)-encoded latency-associated nuclear antigen with inhibition of apoptosis in HHV-8-associated malignancies. Cancer 92: 3076-3084.
-
(2001)
Cancer
, vol.92
, pp. 3076-3084
-
-
Katano, H.1
Sato, Y.2
Sata, T.3
-
41
-
-
0030734037
-
Identification of the gene encoding the major latency-associated nuclear antigen of the Kaposi's sarcoma-associated herpesvirus
-
Kedes, D. H., M. Lagunoff, R. Renne, and D. Ganem. 1997. Identification of the gene encoding the major latency-associated nuclear antigen of the Kaposi's sarcoma-associated herpesvirus. J. Clin. Invest. 100: 2606-2610.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 2606-2610
-
-
Kedes, D.H.1
Lagunoff, M.2
Renne, R.3
Ganem, D.4
-
42
-
-
0031261173
-
Identification of a major latent nuclear antigen, LNA-1, in the human herpesvirus 8 genome
-
Kellam, P., C. Boshoff, D. Whitby, S. Matthews, R. A. Weiss, and S. J. Talbot. 1997. Identification of a major latent nuclear antigen, LNA-1, in the human herpesvirus 8 genome. J. Hum. Virol. 1: 19-29.
-
(1997)
J. Hum. Virol.
, vol.1
, pp. 19-29
-
-
Kellam, P.1
Boshoff, C.2
Whitby, D.3
Matthews, S.4
Weiss, R.A.5
Talbot, S.J.6
-
43
-
-
0032994157
-
Characterization of monoclonal antibodies raised against the latent nuclear antigen of human herpesvirus 8
-
Kellam, P., D. Bourboulia, N. Dupin, C. Shotton, C. Fisher, S. Talbot, C. Boshoff, and R. A. Weiss. 1999. Characterization of monoclonal antibodies raised against the latent nuclear antigen of human herpesvirus 8. J. Virol. 73: 5149-5155.
-
(1999)
J. Virol.
, vol.73
, pp. 5149-5155
-
-
Kellam, P.1
Bourboulia, D.2
Dupin, N.3
Shotton, C.4
Fisher, C.5
Talbot, S.6
Boshoff, C.7
Weiss, R.A.8
-
44
-
-
33751428916
-
Kaposi's sarcoma herpesvirus C-terminal LANA concentrates at pericentromeric and peri-telomeric regions of a subset of mitotic chromosomes
-
Kelley-Clarke, B., M. E. Ballestas, T. Komatsu, and K. M. Kaye. 2007. Kaposi's sarcoma herpesvirus C-terminal LANA concentrates at pericentromeric and peri-telomeric regions of a subset of mitotic chromosomes. Virology 357: 149-157.
-
(2007)
Virology
, vol.357
, pp. 149-157
-
-
Kelley-Clarke, B.1
Ballestas, M.E.2
Komatsu, T.3
Kaye, K.M.4
-
45
-
-
34247112857
-
Determination of Kaposi's sarcoma-associated herpesvirus C-terminal latency-associated nuclear antigen residues mediating chromosome association and DNA binding
-
Kelley-Clarke, B., M. E. Ballestas, V. Srinivasan, A. J. Barbera, T. Komatsu, T. A. Harris, M. Kazanjian, and K. M. Kaye. 2007. Determination of Kaposi's sarcoma-associated herpesvirus C-terminal latency-associated nuclear antigen residues mediating chromosome association and DNA binding. J. Virol. 81: 4348-4356.
-
(2007)
J. Virol.
, vol.81
, pp. 4348-4356
-
-
Kelley-Clarke, B.1
Ballestas, M.E.2
Srinivasan, V.3
Barbera, A.J.4
Komatsu, T.5
Harris, T.A.6
Kazanjian, M.7
Kaye, K.M.8
-
46
-
-
0031666743
-
Persistent infection of Epstein-Barr virus-positive B lymphocytes by human herpesvirus 8
-
Kliche, S., E. Kremmer, W. Hammerschmidt, U. Koszinowski, and J. Haas. 1998. Persistent infection of Epstein-Barr virus-positive B lymphocytes by human herpesvirus 8. J. Virol. 72: 8143-8149.
-
(1998)
J. Virol.
, vol.72
, pp. 8143-8149
-
-
Kliche, S.1
Kremmer, E.2
Hammerschmidt, W.3
Koszinowski, U.4
Haas, J.5
-
47
-
-
0035933745
-
The latencyassociated nuclear antigen of Kaposi's sarcoma-associated herpesvirus transactivates the telomerase reverse transcriptase promoter
-
Knight, J. S., M. A. Cotter II, and E. S. Robertson. 2001. The latencyassociated nuclear antigen of Kaposi's sarcoma-associated herpesvirus transactivates the telomerase reverse transcriptase promoter. J. Biol. Chem. 276: 22971-22978.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 22971-22978
-
-
Knight, J.S.1
Cotter, M.A.I.I.2
Robertson, E.S.3
-
48
-
-
53449095193
-
Concomitant inhibition of Mdm2-p53 interaction and Aurora kinases activates the p53-dependent postmitotic checkpoints and synergistically induces p53-mediated mitochondrial apoptosis along with reduced endoreduplication in acute myelogenous leukemia
-
Kojima, K., M. Konopleva, T. Tsao, H. Nakakuma, and M. Andreeff. 2008. Concomitant inhibition of Mdm2-p53 interaction and Aurora kinases activates the p53-dependent postmitotic checkpoints and synergistically induces p53-mediated mitochondrial apoptosis along with reduced endoreduplication in acute myelogenous leukemia. Blood 112: 2886-2895.
-
(2008)
Blood
, vol.112
, pp. 2886-2895
-
-
Kojima, K.1
Konopleva, M.2
Tsao, T.3
Nakakuma, H.4
Andreeff, M.5
-
49
-
-
0029854672
-
The natural history and molecular heterogeneity of HIV-associated primary malignant lymphomatous effusions
-
Komanduri, K. V., J. A. Luce, M. S. McGrath, B. G. Herndier, and V. L. Ng. 1996. The natural history and molecular heterogeneity of HIV-associated primary malignant lymphomatous effusions. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 13: 215-226.
-
(1996)
J. Acquir. Immune Defic. Syndr. Hum. Retrovirol.
, vol.13
, pp. 215-226
-
-
Komanduri, K.V.1
Luce, J.A.2
McGrath, M.S.3
Herndier, B.G.4
Ng, V.L.5
-
50
-
-
1342321886
-
KSHV LANA1 binds DNA as an oligomer and residues N-terminal to the oligomerization domain are essential for DNA binding, replication, and episome persistence
-
Komatsu, T., M. E. Ballestas, A. J. Barbera, B. Kelley-Clarke, and K. M. Kaye. 2004. KSHV LANA1 binds DNA as an oligomer and residues N- terminal to the oligomerization domain are essential for DNA binding, replication, and episome persistence. Virology 319: 225-236.
-
(2004)
Virology
, vol.319
, pp. 225-236
-
-
Komatsu, T.1
Ballestas, M.E.2
Barbera, A.J.3
Kelley-Clarke, B.4
Kaye, K.M.5
-
51
-
-
0036828167
-
Protein interactions targeting the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus to cell chromosomes
-
Krithivas, A., M. Fujimuro, M. Weidner, D. B. Young, and S. D. Hayward. 2002. Protein interactions targeting the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus to cell chromosomes. J. Virol. 76: 11596-11604.
-
(2002)
J. Virol.
, vol.76
, pp. 11596-11604
-
-
Krithivas, A.1
Fujimuro, M.2
Weidner, M.3
Young, D.B.4
Hayward, S.D.5
-
52
-
-
0033809462
-
Human herpesvirus 8 LANA interacts with proteins of the mSin3 corepressor complex and negatively regulates Epstein-Barr virus gene expression in dually infected PEL cells
-
Krithivas, A., D. B. Young, G. Liao, D. Greene, and S. D. Hayward. 2000. Human herpesvirus 8 LANA interacts with proteins of the mSin3 corepressor complex and negatively regulates Epstein-Barr virus gene expression in dually infected PEL cells. J. Virol. 74: 9637-9645.
-
(2000)
J. Virol.
, vol.74
, pp. 9637-9645
-
-
Krithivas, A.1
Young, D.B.2
Liao, G.3
Greene, D.4
Hayward, S.D.5
-
53
-
-
0030965946
-
Regulation of p53 stability by Mdm2
-
Kubbutat, M. H., S. N. Jones, and K. H. Vousden. 1997. Regulation of p53 stability by Mdm2. Nature 387: 299-303.
-
(1997)
Nature
, vol.387
, pp. 299-303
-
-
Kubbutat, M.H.1
Jones, S.N.2
Vousden, K.H.3
-
54
-
-
0030575937
-
Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain
-
DOI 10.1126/science.274.5289.948
-
Kussie, P. H., S. Gorina, V. Marechal, B. Elenbaas, J. Moreau, A. J. Levine, and N. P. Pavletich. 1996. Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain. Science 274: 948-953. (Pubitemid 26398409)
-
(1996)
Science
, vol.274
, Issue.5289
, pp. 948-953
-
-
Kussie, P.H.1
Gorina, S.2
Marechal, V.3
Elenbaas, B.4
Moreau, J.5
Levine, A.J.6
Pavletich, N.P.7
-
55
-
-
14744269431
-
Kaposi's sarcomaassociated herpesvirus reactivation is regulated by interaction of latencyassociated nuclear antigen with recombination signal sequence-binding protein Jkappa, the major downstream effector of the Notch signaling pathway
-
Lan, K., D. A. Kuppers, and E. S. Robertson. 2005. Kaposi's sarcomaassociated herpesvirus reactivation is regulated by interaction of latencyassociated nuclear antigen with recombination signal sequence-binding protein Jkappa, the major downstream effector of the Notch signaling pathway. J. Virol. 79: 3468-3478.
-
(2005)
J. Virol.
, vol.79
, pp. 3468-3478
-
-
Lan, K.1
Kuppers, D.A.2
Robertson, E.S.3
-
56
-
-
19944370134
-
Induction of Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen by the lytic transactivator RTA: A novel mechanism for establishment of latency
-
Lan, K., D. A. Kuppers, S. C. Verma, N. Sharma, M. Murakami, and E. S. Robertson. 2005. Induction of Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen by the lytic transactivator RTA: a novel mechanism for establishment of latency. J. Virol. 79: 7453-7465.
-
(2005)
J. Virol.
, vol.79
, pp. 7453-7465
-
-
Lan, K.1
Kuppers, D.A.2
Verma, S.C.3
Sharma, N.4
Murakami, M.5
Robertson, E.S.6
-
57
-
-
0018348655
-
T antigen is bound to a host protein in SV40-transformed cells
-
Lane, D. P., and L. V. Crawford. 1979. T antigen is bound to a host protein in SV40-transformed cells. Nature 278: 261-263.
-
(1979)
Nature
, vol.278
, pp. 261-263
-
-
Lane, D.P.1
Crawford, L.V.2
-
58
-
-
0035903219
-
The transcriptional activity of cAMP response element-binding protein-binding protein is modulated by the latency associated nuclear antigen of Kaposi's sarcomaassociated herpesvirus
-
Lim, C., Y. Gwack, S. Hwang, S. Kim, and J. Choe. 2001. The transcriptional activity of cAMP response element-binding protein-binding protein is modulated by the latency associated nuclear antigen of Kaposi's sarcomaassociated herpesvirus. J. Biol. Chem. 276: 31016-31022.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 31016-31022
-
-
Lim, C.1
Gwack, Y.2
Hwang, S.3
Kim, S.4
Choe, J.5
-
59
-
-
0033767391
-
Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8) binds ATF4/CREB2 and inhibits its transcriptional activation activity
-
Lim, C., H. Sohn, Y. Gwack, and J. Choe. 2000. Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8) binds ATF4/CREB2 and inhibits its transcriptional activation activity. J. Gen. Virol. 81: 2645-2652.
-
(2000)
J. Gen. Virol.
, vol.81
, pp. 2645-2652
-
-
Lim, C.1
Sohn, H.2
Gwack, Y.3
Choe, J.4
-
60
-
-
0018760324
-
Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells
-
Linzer, D. I., and A. J. Levine. 1979. Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells. Cell 17: 43-52.
-
(1979)
Cell.
, vol.17
, pp. 43-52
-
-
Linzer, D.I.1
Levine, A.J.2
-
61
-
-
0027319521
-
P53 is required for radiation-induced apoptosis in mouse thymocytes
-
Lowe, S. W., E. M. Schmitt, S. W. Smith, B. A. Osborne, and T. Jacks. 1993. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362: 47-849.
-
(1993)
Nature
, vol.362
, pp. 47-849
-
-
Lowe, S.W.1
Schmitt, E.M.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
62
-
-
33646723291
-
Acetylation of the latency-associated nuclear antigen regulates repression of Kaposi's sarcoma-associated herpesvirus lytic transcription
-
Lu, F., L. Day, S. J. Gao, and P. M. Lieberman. 2006. Acetylation of the latency-associated nuclear antigen regulates repression of Kaposi's sarcoma-associated herpesvirus lytic transcription. J. Virol. 80: 5273-5282.
-
(2006)
J. Virol.
, vol.80
, pp. 5273-5282
-
-
Lu, F.1
Day, L.2
Gao, S.J.3
Lieberman, P.M.4
-
63
-
-
0036136470
-
Latent nuclear antigen of Kaposi's sarcoma herpesvirus/human herpesvirus-8 induces and relocates RING3 to nuclear heterochromatin regions
-
Mattsson, K., C. Kiss, G. M. Platt, G. R. Simpson, E. Kashuba, G. Klein, T. F. Schulz, and L. Szekely. 2002. Latent nuclear antigen of Kaposi's sarcoma herpesvirus/human herpesvirus-8 induces and relocates RING3 to nuclear heterochromatin regions. J. Gen. Virol. 83: 179-188.
-
(2002)
J. Gen. Virol.
, vol.83
, pp. 179-188
-
-
Mattsson, K.1
Kiss, C.2
Platt, G.M.3
Simpson, G.R.4
Kashuba, E.5
Klein, G.6
Schulz, T.F.7
Szekely, L.8
-
64
-
-
0029049828
-
Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors
-
Moll, U. M., M. LaQuaglia, J. Benard, and G. Riou. 1995. Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors. Proc. Natl. Acad. Sci. U. S. A. 92: 4407-4411.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 4407-4411
-
-
Moll, U.M.1
LaQuaglia, M.2
Benard, J.3
Riou, G.4
-
65
-
-
0026649648
-
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
-
Momand, J., G. P. Zambetti, D. C. Olson, D. George, and A. J. Levine. 1992. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 69: 1237-1245.
-
(1992)
Cell.
, vol.69
, pp. 1237-1245
-
-
Momand, J.1
Zambetti, G.P.2
Olson, D.C.3
George, D.4
Levine, A.J.5
-
66
-
-
0029974841
-
Primary effusion lymphoma: A distinct clinicopathologic entity associated with the Kaposi's sarcoma-associated herpes virus
-
Nador, R. G., E. Cesarman, A. Chadburn, D. B. Dawson, M. Q. Ansari, J. Sald, and D. M. Knowles. 1996. Primary effusion lymphoma: a distinct clinicopathologic entity associated with the Kaposi's sarcoma-associated herpes virus. Blood 88: 645-656.
-
(1996)
Blood
, vol.88
, pp. 645-656
-
-
Nador, R.G.1
Cesarman, E.2
Chadburn, A.3
Dawson, D.B.4
Ansari, M.Q.5
Sald, J.6
Knowles, D.M.7
-
67
-
-
0036258111
-
The IARC TP53 database: New online mutation analysis and recommendations to users
-
Olivier, M., R. Eeles, M. Hollstein, M. A. Khan, C. C. Harris, and P. Hainaut. 2002. The IARC TP53 database: new online mutation analysis and recommendations to users. Hum. Mutat. 19: 607-614.
-
(2002)
Hum. Mutat.
, vol.19
, pp. 607-614
-
-
Olivier, M.1
Eeles, R.2
Hollstein, M.3
Khan, M.A.4
Harris, C.C.5
Hainaut, P.6
-
68
-
-
33750356102
-
Kaposi's sarcoma-associated herpesvirus LANA-1 interacts with the short variant of BRD4 and releases cells from a BRD4-and BRD2/RING3-induced G1 cell cycle arrest
-
Ottinger, M., T. Christalla, K. Nathan, M. M. Brinkmann, A. Viejo-Borbolla, and T. F. Schulz. 2006. Kaposi's sarcoma-associated herpesvirus LANA-1 interacts with the short variant of BRD4 and releases cells from a BRD4-and BRD2/RING3-induced G1 cell cycle arrest. J. Virol. 80: 10772-10786.
-
(2006)
J. Virol.
, vol.80
, pp. 10772-10786
-
-
Ottinger, M.1
Christalla, T.2
Nathan, K.3
Brinkmann, M.M.4
Viejo-Borbolla, A.5
Schulz, T.F.6
-
69
-
-
33745870097
-
KSHV targets multiple leukocyte lineages during long-term productive infection in NOD/SCID mice
-
Parsons, C. H., L. A. Adang, J. Overdevest, C. M. O'Connor, J. R. Taylor, Jr., D. Camerini, and D. H. Kedes. 2006. KSHV targets multiple leukocyte lineages during long-term productive infection in NOD/SCID mice. J. Clin. Invest. 116: 1963-1973.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1963-1973
-
-
Parsons, C.H.1
Adang, L.A.2
Overdevest, J.3
O'Connor, C.M.4
Taylor Jr., R.J.5
Camerini, D.6
Kedes, D.H.7
-
70
-
-
33645511223
-
Levels of HdmX expression dictate the sensitivity of normal and transformed cells to Nutlin-3
-
Patton, J. T., L. D. Mayo, A. D. Singhi, A. V. Gudkov, G. R. Stark, and M. W. Jackson. 2006. Levels of HdmX expression dictate the sensitivity of normal and transformed cells to Nutlin-3. Cancer Res. 66: 3169-3176.
-
(2006)
Cancer Res.
, vol.66
, pp. 3169-3176
-
-
Patton, J.T.1
Mayo, L.D.2
Singhi, A.D.3
Gudkov, A.V.4
Stark, G.R.5
Jackson, M.W.6
-
71
-
-
33846794905
-
Functional p53 signaling in Kaposi's sarcoma-associated herpesvirus lymphomas: Implications for therapy
-
Petre, C. E., S. H. Sin, and D. P. Dittmer. 2007. Functional p53 signaling in Kaposi's sarcoma-associated herpesvirus lymphomas: implications for therapy. J. Virol. 81: 1912-1922.
-
(2007)
J. Virol.
, vol.81
, pp. 1912-1922
-
-
Petre, C.E.1
Sin, S.H.2
Dittmer, D.P.3
-
72
-
-
0032752995
-
Latent nuclear antigen of Kaposi's sarcoma-associated herpesvirus interacts with RING3, a homolog of the Drosophila female sterile homeotic (fsh) gene
-
Platt, G. M., G. R. Simpson, S. Mittnacht, and T. F. Schulz. 1999. Latent nuclear antigen of Kaposi's sarcoma-associated herpesvirus interacts with RING3, a homolog of the Drosophila female sterile homeotic (fsh) gene. J. Virol. 73: 9789-9795.
-
(1999)
J. Virol.
, vol.73
, pp. 9789-9795
-
-
Platt, G.M.1
Simpson, G.R.2
Mittnacht, S.3
Schulz, T.F.4
-
73
-
-
0033782793
-
The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras transforms primary rat cells
-
Radkov, S. A., P. Kellam, and C. Boshoff. 2000. The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras transforms primary rat cells. Nat. Med. 6: 1121-1127.
-
(2000)
Nat. Med.
, vol.6
, pp. 1121-1127
-
-
Radkov, S.A.1
Kellam, P.2
Boshoff, C.3
-
74
-
-
0030834122
-
The 222-to 234-kilodalton latent nuclear protein (LNA) of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) is encoded by orf73 and is a component of the latency-associated nuclear antigen
-
Rainbow, L., G. M. Platt, G. R. Simpson, R. Sarid, S. J. Gao, H. Stoiber, C. S. Herrington, P. S. Moore, and T. F. Schulz. 1997. The 222-to 234-kilodalton latent nuclear protein (LNA) of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) is encoded by orf73 and is a component of the latency-associated nuclear antigen. J. Virol. 71: 5915-5921.
-
(1997)
J. Virol.
, vol.71
, pp. 5915-5921
-
-
Rainbow, L.1
Platt, G.M.2
Simpson, G.R.3
Sarid, R.4
Gao, S.J.5
Stoiber, H.6
Herrington, C.S.7
Moore, P.S.8
Schulz, T.F.9
-
75
-
-
0034749459
-
Modulation of cellular and viral gene expression by the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus
-
Renne, R., C. Barry, D. Dittmer, N. Compitello, P. O. Brown, and D. Ganem. 2001. Modulation of cellular and viral gene expression by the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus. J. Virol. 75: 458-468.
-
(2001)
J. Virol.
, vol.75
, pp. 458-468
-
-
Renne, R.1
Barry, C.2
Dittmer, D.3
Compitello, N.4
Brown, P.O.5
Ganem, D.6
-
76
-
-
0031950270
-
Limited transmission of Kaposi's sarcoma-associated herpesvirus in cultured cells
-
Renne, R., D. Blackbourn, D. Whitby, J. Levy, and D. Ganem. 1998. Limited transmission of Kaposi's sarcoma-associated herpesvirus in cultured cells. J. Virol. 72: 5182-5188.
-
(1998)
J. Virol.
, vol.72
, pp. 5182-5188
-
-
Renne, R.1
Blackbourn, D.2
Whitby, D.3
Levy, J.4
Ganem, D.5
-
77
-
-
34147158893
-
Reactivation of the p53 pathway as a treatment modality for KSHV-induced lymphomas
-
Sarek, G., S. Kurki, J. Enback, G. Iotzova, J. Haas, P. Laakkonen, M. Laiho, and P. M. Ojala. 2007. Reactivation of the p53 pathway as a treatment modality for KSHV-induced lymphomas. J. Clin. Invest. 117: 1019-1028.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1019-1028
-
-
Sarek, G.1
Kurki, S.2
Enback, J.3
Iotzova, G.4
Haas, J.5
Laakkonen, P.6
Laiho, M.7
Ojala, P.M.8
-
78
-
-
0033857732
-
Carboxy terminus of human herpesvirus 8 latency-associated nuclear antigen mediates dimerization, transcriptional repression, and targeting to nuclear bodies
-
Schwam, D. R., R. L. Luciano, S. S. Mahajan, L. Wong, and A. C. Wilson. 2000. Carboxy terminus of human herpesvirus 8 latency-associated nuclear antigen mediates dimerization, transcriptional repression, and targeting to nuclear bodies. J. Virol. 74: 8532-8540.
-
(2000)
J. Virol.
, vol.74
, pp. 8532-8540
-
-
Schwam, D.R.1
Luciano, R.L.2
Mahajan, S.S.3
Wong, L.4
Wilson, A.C.5
-
79
-
-
33646574651
-
Functional integrity of the p53-mediated apoptotic pathway induced by the non-genotoxic agent nutlin-3a in B-cell chronic lymphocytic leukemia (B-CLL)
-
Secchiero, P., E. Barbarotto, M. Tiribelli, C. Zerbinati, M. G. di Iasio, A. Gonelli, F. Cavazzini, D. Campioni, R. Fanin, A. Cuneo, and G. Zauli. 2006. Functional integrity of the p53-mediated apoptotic pathway induced by the non-genotoxic agent nutlin-3a in B-cell chronic lymphocytic leukemia (B- CLL). Blood 107: 4122-4129.
-
(2006)
Blood
, vol.107
, pp. 4122-4129
-
-
Secchiero, P.1
Barbarotto, E.2
Tiribelli, M.3
Zerbinati, C.4
Di Iasio, M.G.5
Gonelli, A.6
Cavazzini, F.7
Campioni, D.8
Fanin, R.9
Cuneo, A.10
Zauli, G.11
-
80
-
-
33749243937
-
Recruitment of the de novo DNA methyltransferase Dnmt3a by Kaposi's sarcomaassociated herpesvirus LANA
-
Shamay, M., A. Krithivas, J. Zhang, and S. D. Hayward. 2006. Recruitment of the de novo DNA methyltransferase Dnmt3a by Kaposi's sarcomaassociated herpesvirus LANA. Proc. Natl. Acad. Sci. U. S. A. 103: 14554-14559.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 14554-14559
-
-
Shamay, M.1
Krithivas, A.2
Zhang, J.3
Hayward, S.D.4
-
81
-
-
0036893366
-
Chromosome binding site of latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus is essential for persistent episome maintenance and is functionally replaced by histone H1
-
Shinohara, H., M. Fukushi, M. Higuchi, M. Oie, O. Hoshi, T. Ushiki, J.-I. Hayashi, and M. Fujii. 2002. Chromosome binding site of latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus is essential for persistent episome maintenance and is functionally replaced by histone H1. J. Virol. 76: 12917-12924.
-
(2002)
J. Virol.
, vol.76
, pp. 12917-12924
-
-
Shinohara, H.1
Fukushi, M.2
Higuchi, M.3
Oie, M.4
Hoshi, O.5
Ushiki, T.6
Hayashi, J.-I.7
Fujii, M.8
-
82
-
-
10144259344
-
MDMX: A novel p53-binding protein with some functional properties of MDM2
-
Shvarts, A., W. T. Steegenga, N. Riteco, T. van Laar, P. Dekker, M. Bazuine, R. C. van Ham, W. van der Houven van Oordt, G. Hateboer, A. J. van der Eb, and A. G. Jochemsen. 1996. MDMX: a novel p53-binding protein with some functional properties of MDM2. EMBO J. 15: 5349-5357.
-
(1996)
EMBO J.
, vol.15
, pp. 5349-5357
-
-
Shvarts, A.1
Steegenga, W.T.2
Riteco, N.3
Van Laar, T.4
Dekker, P.5
Bazuine, M.6
Van Ham, R.C.7
Van Der Houven, W.V.O.8
Hateboer, G.9
Van Der Eb, A.J.10
Jochemsen, A.G.11
-
83
-
-
30344456725
-
Kaposi's sarcoma-associated herpesvirusencoded latency-associated nuclear antigen induces chromosomal instability through inhibition of p53 function
-
Si, H., and E. S. Robertson. 2006. Kaposi's sarcoma-associated herpesvirusencoded latency-associated nuclear antigen induces chromosomal instability through inhibition of p53 function. J. Virol. 80: 697-709.
-
(2006)
J. Virol.
, vol.80
, pp. 697-709
-
-
Si, H.1
Robertson, E.S.2
-
84
-
-
33748516780
-
Proteomic analysis of the Kaposi's sarcoma-associated herpesvirus terminal repeat element binding proteins
-
Si, H., S. C. Verma, and E. S. Robertson. 2006. Proteomic analysis of the Kaposi's sarcoma-associated herpesvirus terminal repeat element binding proteins. J. Virol. 80: 9017-9030.
-
(2006)
J. Virol.
, vol.80
, pp. 9017-9030
-
-
Si, H.1
Verma, S.C.2
Robertson, E.S.3
-
85
-
-
10044233111
-
Definition of sequence requirements for latency-associated nuclear antigen 1 binding to Kaposi's sarcoma-associated herpesvirus DNA
-
Srinivasan, V., T. Komatsu, M. E. Ballestas, and K. M. Kaye. 2004. Definition of sequence requirements for latency-associated nuclear antigen 1 binding to Kaposi's sarcoma-associated herpesvirus DNA. J. Virol. 78: 14033-14038.
-
(2004)
J. Virol.
, vol.78
, pp. 14033-14038
-
-
Srinivasan, V.1
Komatsu, T.2
Ballestas, M.E.3
Kaye, K.M.4
-
86
-
-
0034623074
-
Hdmx stabilizes Mdm2 and p53
-
Stad, R., Y. F. Ramos, N. Little, S. Grivell, J. Attema, A. J. van Der Eb, and A. G. Jochemsen. 2000. Hdmx stabilizes Mdm2 and p53. J. Biol. Chem. 275: 28039-28044.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 28039-28044
-
-
Stad, R.1
Ramos, Y.F.2
Little, N.3
Grivell, S.4
Attema, J.5
Van Der Eb, A.J.6
Jochemsen, A.G.7
-
87
-
-
7644241815
-
ORC, MCM, and histone hyperacetylation at the Kaposi's sarcoma-associated herpesvirus latent replication origin
-
Stedman, W., Z. Deng, F. Lu, and P. M. Lieberman. 2004. ORC, MCM, and histone hyperacetylation at the Kaposi's sarcoma-associated herpesvirus latent replication origin. J. Virol. 78: 12566-12575.
-
(2004)
J. Virol.
, vol.78
, pp. 12566-12575
-
-
Stedman, W.1
Deng, Z.2
Lu, F.3
Lieberman, P.M.4
-
88
-
-
55749105875
-
P53-mediated apoptosis of CLL cells: Evidence for a transcription- independent mechanism
-
Steele, A. J., A. G. Prentice, A. V. Hoffbrand, B. C. Yogashangary, S. M. Hart, E. P. Nacheva, J. D. Howard-Reeves, V. M. Duke, P. D. Kottaridis, K. Cwynarski, L. T. Vassilev, and R. G. Wickremasinghe. 2008. p53-mediated apoptosis of CLL cells: evidence for a transcription-independent mechanism. Blood 112: 3827-3834.
-
(2008)
Blood
, vol.112
, pp. 3827-3834
-
-
Steele, A.J.1
Prentice, A.G.2
Hoffbrand, A.V.3
Yogashangary, B.C.4
Hart, S.M.5
Nacheva, E.P.6
Howard-Reeves, J.D.7
Duke, V.M.8
Kottaridis, P.D.9
Cwynarski, K.10
Vassilev, L.T.11
Wickremasinghe, R.G.12
-
89
-
-
0026058990
-
Complex formation between the lymphotropic papovavirus large tumor antigen and the tumor suppressor protein p53
-
Symonds, H., J. D. Chen, and T. Van Dyke. 1991. Complex formation between the lymphotropic papovavirus large tumor antigen and the tumor suppressor protein p53. J. Virol. 65: 5417-5424.
-
(1991)
J. Virol.
, vol.65
, pp. 5417-5424
-
-
Symonds, H.1
Chen, J.D.2
Van Dyke, T.3
-
90
-
-
0032742998
-
Human herpesvirus-8-encoded LNA-1 accumulates in heterochromatin- associated nuclear bodies
-
Szekely, L., C. Kiss, K. Mattsson, E. Kashuba, K. Pokrovskaja, A. Juhasz, P. Holmvall, and G. Klein. 1999. Human herpesvirus-8-encoded LNA-1 accumulates in heterochromatin-associated nuclear bodies. J. Gen. Virol. 80: 2889-9000.
-
(1999)
J. Gen. Virol.
, vol.80
, pp. 2889-9000
-
-
Szekely, L.1
Kiss, C.2
Mattsson, K.3
Kashuba, E.4
Pokrovskaja, K.5
Juhasz, A.6
Holmvall, P.7
Klein, G.8
-
91
-
-
0033051322
-
MDM2 interacts with MDMX through their RING finger domains
-
Tanimura, S., S. Ohtsuka, K. Mitsui, K. Shirouzu, A. Yoshimura, and M. Ohtsubo. 1999. MDM2 interacts with MDMX through their RING finger domains. FEBS Lett. 447: 5-9.
-
(1999)
FEBS Lett.
, vol.447
, pp. 5-9
-
-
Tanimura, S.1
Ohtsuka, S.2
Mitsui, K.3
Shirouzu, K.4
Yoshimura, A.5
Ohtsubo, M.6
-
92
-
-
0032980646
-
Nucleocytoplasmic shuttlingof oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53
-
Tao, W., and A. J. Levine. 1999. Nucleocytoplasmic shuttlingof oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53. Proc. Natl. Acad. Sci. U. S. A. 96: 3077-3080.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 3077-3080
-
-
Tao, W.1
Levine, A.J.2
-
93
-
-
0028224571
-
Stabilization of the tumor suppressor p53 during cellular transformation by simian virus 40: Influence of viral and cellular factors and biological consequences
-
Tiemann, F., and W. Deppert. 1994. Stabilization of the tumor suppressor p53 during cellular transformation by simian virus 40: influence of viral and cellular factors and biological consequences. J. Virol. 68: 2869-2878.
-
(1994)
J. Virol.
, vol.68
, pp. 2869-2878
-
-
Tiemann, F.1
Deppert, W.2
-
94
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
-
Vassilev, L. T., B. T. Vu, B. Graves, D. Carvajal, F. Podlaski, Z. Filipovic, N. Kong, U. Kammlott, C. Lukacs, C. Klein, N. Fotouhi, and E. A. Liu. 2004. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 303: 844-848.
-
(2004)
Science
, vol.303
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
Filipovic, Z.6
Kong, N.7
Kammlott, U.8
Lukacs, C.9
Klein, C.10
Fotouhi, N.11
Liu, E.A.12
-
95
-
-
4544290097
-
Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus up-regulates transcription of human telomerase reverse transcriptase promoter through interaction with transcription factor Sp1
-
Verma, S. C., S. Borah, and E. S. Robertson. 2004. Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus up-regulates transcription of human telomerase reverse transcriptase promoter through interaction with transcription factor Sp1. J. Virol. 78: 10348-10359.
-
(2004)
J. Virol.
, vol.78
, pp. 10348-10359
-
-
Verma, S.C.1
Borah, S.2
Robertson, E.S.3
-
96
-
-
33144488605
-
Latencyassociated nuclear antigen (LANA) of Kaposi's sarcoma-associated herpesvirus interacts with origin recognition complexes at the LANA binding sequence within the terminal repeats
-
Verma, S. C., T. Choudhuri, R. Kaul, and E. S. Robertson. 2006. Latencyassociated nuclear antigen (LANA) of Kaposi's sarcoma-associated herpesvirus interacts with origin recognition complexes at the LANA binding sequence within the terminal repeats. J. Virol. 80: 2243-2256.
-
(2006)
J. Virol.
, vol.80
, pp. 2243-2256
-
-
Verma, S.C.1
Choudhuri, T.2
Kaul, R.3
Robertson, E.S.4
-
97
-
-
0038279735
-
A domain in the C-terminal region of latency-associated nuclear antigen 1 of Kaposi's sarcoma-associated herpesvirus affects transcriptional activation and binding to nuclear heterochromatin
-
Viejo-Borbolla, A., E. Kati, J. A. Sheldon, K. Nathan, K. Mattsson, L. Szekely, and T. F. Schulz. 2003. A domain in the C-terminal region of latency-associated nuclear antigen 1 of Kaposi's sarcoma-associated herpesvirus affects transcriptional activation and binding to nuclear heterochromatin. J. Virol. 77: 7093-7100.
-
(2003)
J. Virol.
, vol.77
, pp. 7093-7100
-
-
Viejo-Borbolla, A.1
Kati, E.2
Sheldon, J.A.3
Nathan, K.4
Mattsson, K.5
Szekely, L.6
Schulz, T.F.7
-
98
-
-
27144433485
-
Brd2/RING3 interacts with a chromatin-binding domain in the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 (LANA-1) that is required for multiple functions of LANA-1
-
Viejo-Borbolla, A., M. Ottinger, E. Bruning, A. Burger, R. Konig, E. Kati, J. A. Sheldon, and T. F. Schulz. 2005. Brd2/RING3 interacts with a chromatin-binding domain in the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 (LANA-1) that is required for multiple functions of LANA-1. J. Virol. 79: 13618-13629.
-
(2005)
J. Virol.
, vol.79
, pp. 13618-13629
-
-
Viejo-Borbolla, A.1
Ottinger, M.2
Bruning, E.3
Burger, A.4
Konig, R.5
Kati, E.6
Sheldon, J.A.7
Schulz, T.F.8
-
99
-
-
34547615407
-
Quantitative analyses reveal the importance of regulated Hdmx degradation for p53 activation
-
Wang, Y. V., M. Wade, E. Wong, Y. C. Li, L. W. Rodewald, and G. M. Wahl. 2007. Quantitative analyses reveal the importance of regulated Hdmx degradation for p53 activation. Proc. Natl. Acad. Sci. U. S. A. 104: 12365-12370.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 12365-12370
-
-
Wang, Y.V.1
Wade, M.2
Wong, E.3
Li, Y.C.4
Rodewald, L.W.5
Wahl, G.M.6
-
100
-
-
4444384335
-
Transcriptional activation by the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen is facilitated by an N-terminal chromatin-binding motif
-
Wong, L. Y., G. A. Matchett, and A. C. Wilson. 2004. Transcriptional activation by the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen is facilitated by an N-terminal chromatin-binding motif. J. Virol. 78: 10074-10085.
-
(2004)
J. Virol.
, vol.78
, pp. 10074-10085
-
-
Wong, L.Y.1
Matchett, G.A.2
Wilson, A.C.3
-
101
-
-
27144521962
-
Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen induces a strong bend on binding to terminal repeat DNA
-
Wong, L. Y., and A. C. Wilson. 2005. Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen induces a strong bend on binding to terminal repeat DNA. J. Virol. 79: 13829-13836.
-
(2005)
J. Virol.
, vol.79
, pp. 13829-13836
-
-
Wong, L.Y.1
Wilson, A.C.2
-
102
-
-
0027244853
-
The p53-mdm-2 autoregulatory feedback loop
-
Wu, X., J. H. Bayle, D. Olson, and A. J. Levine. 1993. The p53-mdm-2 autoregulatory feedback loop. Genes Dev. 7: 1126-1132.
-
(1993)
Genes Dev.
, vol.7
, pp. 1126-1132
-
-
Wu, X.1
Bayle, J.H.2
Olson, D.3
Levine, A.J.4
-
103
-
-
4644232252
-
Disruption of Kaposi's sarcoma-associated herpesvirus latent nuclear antigen leads to abortive episome persistence
-
Ye, F. C., F. C. Zhou, S. M. Yoo, J. P. Xie, P. J. Browning, and S. J. Gao. 2004. Disruption of Kaposi's sarcoma-associated herpesvirus latent nuclear antigen leads to abortive episome persistence. J. Virol. 78: 11121-11129.
-
(2004)
J. Virol.
, vol.78
, pp. 11121-11129
-
-
Ye, F.C.1
Zhou, F.C.2
Yoo, S.M.3
Xie, J.P.4
Browning, P.J.5
Gao, S.J.6
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