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Volumn 148, Issue , 2016, Pages 293-304

Higher mitochondrial potential and elevated mitochondrial respiration are associated with excessive activation of blood platelets in diabetic rats

Author keywords

Blood platelets; Diabetes mellitus; Mitochondrial membrane potential; Mitochondrial respiration; Platelet activation and reactivity

Indexed keywords

BETA3 INTEGRIN; CYTOCHROME C OXIDASE; MITOCHONDRIAL PROTEIN; PADGEM PROTEIN; STREPTOZOCIN;

EID: 84959010359     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2016.02.030     Document Type: Article
Times cited : (21)

References (69)
  • 1
    • 84937395958 scopus 로고    scopus 로고
    • Aortic intima-media thickness and mean platelet volume in children with type 1 diabetes mellitus
    • M. Ersoy, H.N. Selcuk Duru, M. Elevli, O. Ersoy, and M. Civilibal Aortic intima-media thickness and mean platelet volume in children with type 1 diabetes mellitus Iran. J. Pediatr. 25 2015 e368
    • (2015) Iran. J. Pediatr. , vol.25 , pp. e368
    • Ersoy, M.1    Selcuk Duru, H.N.2    Elevli, M.3    Ersoy, O.4    Civilibal, M.5
  • 2
    • 84964732787 scopus 로고    scopus 로고
    • Dyslipidaemia of diabetes and the intestine
    • G.H. Tomkin, and D. Owens Dyslipidaemia of diabetes and the intestine World J. Diabetes 6 2015 970 977
    • (2015) World J. Diabetes , vol.6 , pp. 970-977
    • Tomkin, G.H.1    Owens, D.2
  • 3
    • 21044457137 scopus 로고    scopus 로고
    • Blood platelet reactivity and its pharmacological modulation in (people with) diabetes mellitus
    • C. Watala Blood platelet reactivity and its pharmacological modulation in (people with) diabetes mellitus Curr. Pharm. Des. 11 2005 2331 2365
    • (2005) Curr. Pharm. Des. , vol.11 , pp. 2331-2365
    • Watala, C.1
  • 5
    • 0023712653 scopus 로고
    • Platelets and atherosclerosis
    • J.C. Hoak Platelets and atherosclerosis Semin. Thromb. Hemost. 14 1988 202 205
    • (1988) Semin. Thromb. Hemost. , vol.14 , pp. 202-205
    • Hoak, J.C.1
  • 7
  • 8
    • 84926489967 scopus 로고    scopus 로고
    • Platelets and the complement cascade in atherosclerosis
    • (eCollection;%2015.:49)
    • J. Patzelt, A. Verschoor, and H.F. Langer Platelets and the complement cascade in atherosclerosis Front. Physiol. 6 2015 49 10.3389/fphys.2015.00049 (eCollection;%2015.:49)
    • (2015) Front. Physiol. , vol.6 , pp. 49
    • Patzelt, J.1    Verschoor, A.2    Langer, H.F.3
  • 9
    • 0019516879 scopus 로고
    • Interrelationships among platelet responses: Studies on the burst in proton liberation, lactate production, and oxygen uptake during platelet aggregation and Ca2 + secretion
    • J.W. Akkerman, and H. Holmsen Interrelationships among platelet responses: Studies on the burst in proton liberation, lactate production, and oxygen uptake during platelet aggregation and Ca2 + secretion Blood 57 1981 956 966
    • (1981) Blood , vol.57 , pp. 956-966
    • Akkerman, J.W.1    Holmsen, H.2
  • 12
    • 0033386202 scopus 로고    scopus 로고
    • Mitochondria in neurodegeneration: Bioenergetic function in cell life and death
    • A.N. Murphy, G. Fiskum, and M.F. Beal Mitochondria in neurodegeneration: Bioenergetic function in cell life and death J. Cereb. Blood Flow Metab. 19 1999 231 245
    • (1999) J. Cereb. Blood Flow Metab. , vol.19 , pp. 231-245
    • Murphy, A.N.1    Fiskum, G.2    Beal, M.F.3
  • 13
    • 82755197943 scopus 로고    scopus 로고
    • Nutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetes
    • S.K. Chowdhury, R.T. Dobrowsky, and P. Fernyhough Nutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetes Mitochondrion 11 2011 845 854
    • (2011) Mitochondrion , vol.11 , pp. 845-854
    • Chowdhury, S.K.1    Dobrowsky, R.T.2    Fernyhough, P.3
  • 14
    • 0041925099 scopus 로고
    • Metabolism of platelets
    • W.J. Williams, (New York)
    • H. Holmsen Metabolism of platelets W.J. Williams, Hematology 1990 1200 1233 (New York)
    • (1990) Hematology , pp. 1200-1233
    • Holmsen, H.1
  • 15
    • 0029112506 scopus 로고
    • GLUT-3 (brain-type) glucose transporter polypeptides in human blood platelets
    • J.D. Craik, M. Stewart, and C.I. Cheeseman GLUT-3 (brain-type) glucose transporter polypeptides in human blood platelets Thromb. Res. 79 1995 461 469
    • (1995) Thromb. Res. , vol.79 , pp. 461-469
    • Craik, J.D.1    Stewart, M.2    Cheeseman, C.I.3
  • 16
    • 0347316398 scopus 로고    scopus 로고
    • The role of adenosine triphosphate citrate lyase in the metabolism of acetyl coenzyme a and function of blood platelets in diabetes mellitus
    • A. Michno, A. Skibowska, A. Raszeja-Specht, J. Cwikowska, and A. Szutowicz The role of adenosine triphosphate citrate lyase in the metabolism of acetyl coenzyme a and function of blood platelets in diabetes mellitus Metabolism 53 2004 66 72
    • (2004) Metabolism , vol.53 , pp. 66-72
    • Michno, A.1    Skibowska, A.2    Raszeja-Specht, A.3    Cwikowska, J.4    Szutowicz, A.5
  • 17
    • 24144502077 scopus 로고    scopus 로고
    • Effect of l-carnitine on acetyl-CoA content and activity of blood platelets in healthy and diabetic persons
    • A. Michno, A. Raszeja-Specht, A. Jankowska-Kulawy, T. Pawelczyk, and A. Szutowicz Effect of l-carnitine on acetyl-CoA content and activity of blood platelets in healthy and diabetic persons Clin. Chem. 51 2005 1673 1682
    • (2005) Clin. Chem. , vol.51 , pp. 1673-1682
    • Michno, A.1    Raszeja-Specht, A.2    Jankowska-Kulawy, A.3    Pawelczyk, T.4    Szutowicz, A.5
  • 18
    • 0142093136 scopus 로고    scopus 로고
    • Platelet function and acetyl-coenzyme A metabolism in type 1 diabetes mellitus
    • A. Skibowska, A. Raszeja-Specht, and A. Szutowicz Platelet function and acetyl-coenzyme A metabolism in type 1 diabetes mellitus Clin. Chem. Lab. Med. 41 2003 1136 1143
    • (2003) Clin. Chem. Lab. Med. , vol.41 , pp. 1136-1143
    • Skibowska, A.1    Raszeja-Specht, A.2    Szutowicz, A.3
  • 19
  • 20
    • 0036343879 scopus 로고    scopus 로고
    • Electron dense chains and clusters in human platelets
    • J.G. White Electron dense chains and clusters in human platelets Platelets 13 2002 317 325
    • (2002) Platelets , vol.13 , pp. 317-325
    • White, J.G.1
  • 21
    • 0032551768 scopus 로고    scopus 로고
    • Adenosine 5′-triphosphate: An intracellular metabolic messenger
    • A. Szewczyk, and S. Pikula Adenosine 5′-triphosphate: An intracellular metabolic messenger Biochim. Biophys. Acta 20 1365 1998 333 353
    • (1998) Biochim. Biophys. Acta , vol.20 , Issue.1365 , pp. 333-353
    • Szewczyk, A.1    Pikula, S.2
  • 23
    • 0034993177 scopus 로고    scopus 로고
    • Hyperglycemia potentiates collagen-induced platelet activation through mitochondrial superoxide overproduction
    • S.I. Yamagishi, D. Edelstein, X.L. Du, and M. Brownlee Hyperglycemia potentiates collagen-induced platelet activation through mitochondrial superoxide overproduction Diabetes 50 2001 1491 1494
    • (2001) Diabetes , vol.50 , pp. 1491-1494
    • Yamagishi, S.I.1    Edelstein, D.2    Du, X.L.3    Brownlee, M.4
  • 24
    • 0020571544 scopus 로고
    • The participation of hydroperoxides and oxygen radicals in the control of prostaglandin synthesis
    • L. Taylor, M.J. Menconi, and P. Polgar The participation of hydroperoxides and oxygen radicals in the control of prostaglandin synthesis J. Biol. Chem. 258 1983 6855 6857
    • (1983) J. Biol. Chem. , vol.258 , pp. 6855-6857
    • Taylor, L.1    Menconi, M.J.2    Polgar, P.3
  • 25
    • 84860845827 scopus 로고    scopus 로고
    • The use of animal models in diabetes research
    • A.J. King The use of animal models in diabetes research Br. J. Pharmacol. 166 2012 877 894
    • (2012) Br. J. Pharmacol. , vol.166 , pp. 877-894
    • King, A.J.1
  • 26
    • 0035883087 scopus 로고    scopus 로고
    • The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40
    • V. Henn, S. Steinbach, K. Buchner, P. Presek, and R.A. Kroczek The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40 Blood 98 2001 1047 1054
    • (2001) Blood , vol.98 , pp. 1047-1054
    • Henn, V.1    Steinbach, S.2    Buchner, K.3    Presek, P.4    Kroczek, R.A.5
  • 27
    • 84893676593 scopus 로고    scopus 로고
    • Various laboratory protocols for measuring thromboxane A2 generation to detect the effectiveness of acetylsalicylic acid therapy: A comparative study
    • M. Rozalski, C. Watala, and J. Golanski Various laboratory protocols for measuring thromboxane A2 generation to detect the effectiveness of acetylsalicylic acid therapy: A comparative study Blood Coagul. Fibrinolysis 25 2014 46 51
    • (2014) Blood Coagul. Fibrinolysis , vol.25 , pp. 46-51
    • Rozalski, M.1    Watala, C.2    Golanski, J.3
  • 28
    • 84900485136 scopus 로고    scopus 로고
    • Platelet activation patterns are different in mouse models of diabetes and chronic inhibition of nitric oxide synthesis
    • M. Rozalski, H. Kassassir, K. Siewiera, A. Klepacka, R. Sychowski, and C. Watala Platelet activation patterns are different in mouse models of diabetes and chronic inhibition of nitric oxide synthesis Thromb. Res. 133 2014 1097 1104
    • (2014) Thromb. Res. , vol.133 , pp. 1097-1104
    • Rozalski, M.1    Kassassir, H.2    Siewiera, K.3    Klepacka, A.4    Sychowski, R.5    Watala, C.6
  • 29
    • 84958150209 scopus 로고    scopus 로고
    • High-resolution respirometry with cultured cells: A demonstration experiment
    • E. Gnaiger, second ed. Ed. Innsbruck, OROBOROS MiPNet Publications
    • E. Gnaiger, and K. Renner-Sattler high-resolution respirometry with cultured cells: A demonstration experiment E. Gnaiger, Mitochondrial Pathways and Respiratory Control second ed. 2009 Ed. Innsbruck, OROBOROS MiPNet Publications 62 73
    • (2009) Mitochondrial Pathways and Respiratory Control , pp. 62-73
    • Gnaiger, E.1    Renner-Sattler, K.2
  • 30
    • 12544255068 scopus 로고    scopus 로고
    • The mitochondrial membrane potential in human platelets: A sensitive parameter for platelet quality
    • A.J. Verhoeven, R. Verhaar, E.G. Gouwerok, and K.D. De The mitochondrial membrane potential in human platelets: A sensitive parameter for platelet quality Transfusion 45 2005 82 89
    • (2005) Transfusion , vol.45 , pp. 82-89
    • Verhoeven, A.J.1    Verhaar, R.2    Gouwerok, E.G.3    De, K.D.4
  • 31
    • 33748691383 scopus 로고    scopus 로고
    • Preparation of animals for research-issues to consider for rodents and rabbits
    • L.A. Conour, K.A. Murray, and M.J. Brown Preparation of animals for research-issues to consider for rodents and rabbits ILAR J. 47 2006 283 293
    • (2006) ILAR J. , vol.47 , pp. 283-293
    • Conour, L.A.1    Murray, K.A.2    Brown, M.J.3
  • 33
    • 79953180902 scopus 로고    scopus 로고
    • Assessing mitochondrial dysfunction in cells
    • M.D. Brand, and D.G. Nicholls Assessing mitochondrial dysfunction in cells Biochem. J. 435 2011 297 312
    • (2011) Biochem. J. , vol.435 , pp. 297-312
    • Brand, M.D.1    Nicholls, D.G.2
  • 34
    • 0141755317 scopus 로고    scopus 로고
    • Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: Potential role in diabetic nephropathy
    • S. Kiritoshi, T. Nishikawa, K. Sonoda, D. Kukidome, T. Senokuchi, T. Matsuo, T. Matsumura, H. Tokunaga, M. Brownlee, and E. Araki Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: Potential role in diabetic nephropathy Diabetes 52 2003 2570 2577
    • (2003) Diabetes , vol.52 , pp. 2570-2577
    • Kiritoshi, S.1    Nishikawa, T.2    Sonoda, K.3    Kukidome, D.4    Senokuchi, T.5    Matsuo, T.6    Matsumura, T.7    Tokunaga, H.8    Brownlee, M.9    Araki, E.10
  • 35
    • 33644749330 scopus 로고    scopus 로고
    • Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells
    • D. Kukidome, T. Nishikawa, K. Sonoda, K. Imoto, K. Fujisawa, M. Yano, H. Motoshima, T. Taguchi, T. Matsumura, and E. Araki Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells Diabetes 55 2006 120 127
    • (2006) Diabetes , vol.55 , pp. 120-127
    • Kukidome, D.1    Nishikawa, T.2    Sonoda, K.3    Imoto, K.4    Fujisawa, K.5    Yano, M.6    Motoshima, H.7    Taguchi, T.8    Matsumura, T.9    Araki, E.10
  • 36
    • 84860251058 scopus 로고    scopus 로고
    • Platelet mitochondrial dysfunction is evident in type 2 diabetes in association with modifications of mitochondrial anti-oxidant stress proteins
    • C. Avila, R.J. Huang, M.V. Stevens, A.M. Aponte, D. Tripodi, K.Y. Kim, and M.N. Sack Platelet mitochondrial dysfunction is evident in type 2 diabetes in association with modifications of mitochondrial anti-oxidant stress proteins Exp. Clin. Endocrinol. Diabetes 120 2012 248 251
    • (2012) Exp. Clin. Endocrinol. Diabetes , vol.120 , pp. 248-251
    • Avila, C.1    Huang, R.J.2    Stevens, M.V.3    Aponte, A.M.4    Tripodi, D.5    Kim, K.Y.6    Sack, M.N.7
  • 38
    • 78549296744 scopus 로고    scopus 로고
    • Temporal increase of platelet mitochondrial respiration is negatively associated with clinical outcome in patients with sepsis
    • F. Sjovall, S. Morota, M.J. Hansson, H. Friberg, E. Gnaiger, and E. Elmer Temporal increase of platelet mitochondrial respiration is negatively associated with clinical outcome in patients with sepsis Crit. Care 14 2010 R214
    • (2010) Crit. Care , vol.14 , pp. R214
    • Sjovall, F.1    Morota, S.2    Hansson, M.J.3    Friberg, H.4    Gnaiger, E.5    Elmer, E.6
  • 40
    • 34547588219 scopus 로고    scopus 로고
    • Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: Evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents
    • N. Turner, C.R. Bruce, S.M. Beale, K.L. Hoehn, T. So, M.S. Rolph, and G.J. Cooney Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: Evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents Diabetes 56 2007 2085 2092
    • (2007) Diabetes , vol.56 , pp. 2085-2092
    • Turner, N.1    Bruce, C.R.2    Beale, S.M.3    Hoehn, K.L.4    So, T.5    Rolph, M.S.6    Cooney, G.J.7
  • 42
    • 84862698714 scopus 로고    scopus 로고
    • Endothelial cell and platelet bioenergetics: Effect of glucose and nutrient composition
    • B.D. Fink, J.A. Herlein, Y. O'Malley, and W.I. Sivitz Endothelial cell and platelet bioenergetics: Effect of glucose and nutrient composition PLoS One 7 2012 e39430
    • (2012) PLoS One , vol.7
    • Fink, B.D.1    Herlein, J.A.2    O'Malley, Y.3    Sivitz, W.I.4
  • 44
    • 84872246752 scopus 로고    scopus 로고
    • Glucose ameliorates the metabolic profile and mitochondrial function of platelet concentrates during storage in autologous plasma
    • A.M. Amorini, M. Tuttobene, F.M. Tomasello, F. Biazzo, S. Gullotta, P.V. De, G. Lazzarino, and B. Tavazzi Glucose ameliorates the metabolic profile and mitochondrial function of platelet concentrates during storage in autologous plasma Blood Transfus. 11 2013 61 70
    • (2013) Blood Transfus. , vol.11 , pp. 61-70
    • Amorini, A.M.1    Tuttobene, M.2    Tomasello, F.M.3    Biazzo, F.4    Gullotta, S.5    De, P.V.6    Lazzarino, G.7    Tavazzi, B.8
  • 46
    • 4544264062 scopus 로고    scopus 로고
    • Mitochondrial membrane potential and aging
    • D.G. Nicholls Mitochondrial membrane potential and aging Aging Cell 3 2004 35 40
    • (2004) Aging Cell , vol.3 , pp. 35-40
    • Nicholls, D.G.1
  • 49
  • 51
    • 63049127020 scopus 로고    scopus 로고
    • Mitochondrial superoxide plays a crucial role in the development of mitochondrial dysfunction during high glucose exposure in rat renal proximal tubular cells
    • S. Munusamy, and L.A. MacMillan-Crow Mitochondrial superoxide plays a crucial role in the development of mitochondrial dysfunction during high glucose exposure in rat renal proximal tubular cells Free Radic. Biol. Med. 46 2009 1149 1157
    • (2009) Free Radic. Biol. Med. , vol.46 , pp. 1149-1157
    • Munusamy, S.1    MacMillan-Crow, L.A.2
  • 52
    • 73649135327 scopus 로고    scopus 로고
    • Platelets of type 2 diabetic patients are characterized by high ATP content and low mitochondrial membrane potential
    • X. Guo, J. Wu, J. Du, J. Ran, and J. Xu Platelets of type 2 diabetic patients are characterized by high ATP content and low mitochondrial membrane potential Platelets 20 2009 588 593
    • (2009) Platelets , vol.20 , pp. 588-593
    • Guo, X.1    Wu, J.2    Du, J.3    Ran, J.4    Xu, J.5
  • 53
    • 1942453308 scopus 로고    scopus 로고
    • The mtDNA T8993G (NARP) mutation results in an impairment of oxidative phosphorylation that can be improved by antioxidants
    • M. Mattiazzi, C. Vijayvergiya, C.D. Gajewski, D.C. DeVivo, G. Lenaz, M. Wiedmann, and G. Manfredi The mtDNA T8993G (NARP) mutation results in an impairment of oxidative phosphorylation that can be improved by antioxidants Hum. Mol. Genet. 13 2004 869 879
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 869-879
    • Mattiazzi, M.1    Vijayvergiya, C.2    Gajewski, C.D.3    Devivo, D.C.4    Lenaz, G.5    Wiedmann, M.6    Manfredi, G.7
  • 54
    • 79952068012 scopus 로고    scopus 로고
    • Metabolism, hypoxia and the diabetic heart
    • L.C. Heather, and K. Clarke Metabolism, hypoxia and the diabetic heart J. Mol. Cell. Cardiol. 50 2011 598 605
    • (2011) J. Mol. Cell. Cardiol. , vol.50 , pp. 598-605
    • Heather, L.C.1    Clarke, K.2
  • 56
    • 77957365020 scopus 로고    scopus 로고
    • Mitochondrial proteome analysis reveals altered expression of voltage dependent anion channels in pancreatic beta-cells exposed to high glucose
    • M. Ahmed, S.J. Muhammed, B. Kessler, and A. Salehi Mitochondrial proteome analysis reveals altered expression of voltage dependent anion channels in pancreatic beta-cells exposed to high glucose Islets 2 2010 283 292
    • (2010) Islets , vol.2 , pp. 283-292
    • Ahmed, M.1    Muhammed, S.J.2    Kessler, B.3    Salehi, A.4
  • 58
    • 58449087663 scopus 로고    scopus 로고
    • Mitochondria regulate platelet metamorphosis induced by opsonized zymosan A-activation and long-term commitment to cell death
    • P. Matarrese, E. Straface, G. Palumbo, M. Anselmi, L. Gambardella, B. Ascione, P.D. Del, and W. Malorni Mitochondria regulate platelet metamorphosis induced by opsonized zymosan A-activation and long-term commitment to cell death FEBS J. 276 2009 845 856
    • (2009) FEBS J. , vol.276 , pp. 845-856
    • Matarrese, P.1    Straface, E.2    Palumbo, G.3    Anselmi, M.4    Gambardella, L.5    Ascione, B.6    Del, P.D.7    Malorni, W.8
  • 59
    • 79958058120 scopus 로고    scopus 로고
    • Effects of panax quinquefolium on streptozotocin-induced diabetic rats: Role of C-peptide, nitric oxide and oxidative stress
    • K.A. Amin, E.M. Awad, and M.A. Nagy Effects of panax quinquefolium on streptozotocin-induced diabetic rats: Role of C-peptide, nitric oxide and oxidative stress Int. J. Clin. Exp. Med. 4 2011 136 147
    • (2011) Int. J. Clin. Exp. Med. , vol.4 , pp. 136-147
    • Amin, K.A.1    Awad, E.M.2    Nagy, M.A.3
  • 60
    • 0037443545 scopus 로고    scopus 로고
    • Transcript profiling of human platelets using microarray and serial analysis of gene expression
    • D.V. Gnatenko, J.J. Dunn, S.R. McCorkle, D. Weissmann, P.L. Perrotta, and W.F. Bahou Transcript profiling of human platelets using microarray and serial analysis of gene expression Blood 101 2003 2285 2293
    • (2003) Blood , vol.101 , pp. 2285-2293
    • Gnatenko, D.V.1    Dunn, J.J.2    McCorkle, S.R.3    Weissmann, D.4    Perrotta, P.L.5    Bahou, W.F.6
  • 62
    • 0038271638 scopus 로고    scopus 로고
    • Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts
    • C.S. Stump, K.R. Short, M.L. Bigelow, J.M. Schimke, and K.S. Nair Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts Proc. Natl. Acad. Sci. U. S. A. 100 2003 7996 8001
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 7996-8001
    • Stump, C.S.1    Short, K.R.2    Bigelow, M.L.3    Schimke, J.M.4    Nair, K.S.5
  • 63
    • 0025082198 scopus 로고
    • Insulin stimulates mitochondrial protein synthesis and respiration in isolated perfused rat heart
    • E.E. McKee, and B.L. Grier Insulin stimulates mitochondrial protein synthesis and respiration in isolated perfused rat heart Am. J. Physiol. 259 1990 E413 E421
    • (1990) Am. J. Physiol. , vol.259 , pp. E413-E421
    • McKee, E.E.1    Grier, B.L.2
  • 64
    • 80053508880 scopus 로고    scopus 로고
    • Platelet function in patients with diabetes mellitus: From a theoretical to a practical perspective
    • (Epub;%2011 Aug 21.:742719, 2011)
    • N. Kakouros, J.J. Rade, A. Kourliouros, and J.R. Resar Platelet function in patients with diabetes mellitus: From a theoretical to a practical perspective Int. J. Endocrinol. 2011 742719 10.1155/2011/742719 (Epub;%2011 Aug 21.:742719, 2011)
    • (2011) Int. J. Endocrinol.
    • Kakouros, N.1    Rade, J.J.2    Kourliouros, A.3    Resar, J.R.4
  • 65
    • 0035887540 scopus 로고    scopus 로고
    • Insulin enhances platelet activation in vitro
    • M. Yngen, N. Li, P. Hjemdahl, and N.H. Wallen Insulin enhances platelet activation in vitro Thromb. Res. 104 2001 85 91
    • (2001) Thromb. Res. , vol.104 , pp. 85-91
    • Yngen, M.1    Li, N.2    Hjemdahl, P.3    Wallen, N.H.4
  • 66
    • 0027931376 scopus 로고
    • Insulin increases guanosine-3′,5′-cyclic monophosphate in human platelets. A mechanism involved in the insulin anti-aggregating effect
    • M. Trovati, P. Massucco, L. Mattiello, E. Mularoni, F. Cavalot, and G. Anfossi Insulin increases guanosine-3′,5′-cyclic monophosphate in human platelets. A mechanism involved in the insulin anti-aggregating effect Diabetes 43 1994 1015 1019
    • (1994) Diabetes , vol.43 , pp. 1015-1019
    • Trovati, M.1    Massucco, P.2    Mattiello, L.3    Mularoni, E.4    Cavalot, F.5    Anfossi, G.6
  • 67
    • 17344381445 scopus 로고    scopus 로고
    • Recombinant insulin-like growth factor-1 modulates aggregation in human platelets via extracellular calcium
    • A.S. Motani, E.E. Anggard, and G.A. Ferns Recombinant insulin-like growth factor-1 modulates aggregation in human platelets via extracellular calcium Life Sci. 58 1996 L269 L274
    • (1996) Life Sci. , vol.58 , pp. L269-L274
    • Motani, A.S.1    Anggard, E.E.2    Ferns, G.A.3
  • 68
    • 0032511566 scopus 로고    scopus 로고
    • Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group
    • UK Prospective Diabetes Study (UKPDS) Group Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group Lancet 352 1998 854 865
    • (1998) Lancet , vol.352 , pp. 854-865
  • 69
    • 84890343549 scopus 로고    scopus 로고
    • Acetylsalicylic acid therapy: Influence of metformin use and other variables on urinary 11-dehydrothromboxane B2 levels
    • (Epub;%2013 Dec 4.:76-78)
    • L.H. Goncalves, M.V. Silva, R.C. Duarte, L.M. Dusse, A.P. Fernandes, A.A. Bosco, K.B. Gomes, and M. Carvalho Acetylsalicylic acid therapy: Influence of metformin use and other variables on urinary 11-dehydrothromboxane B2 levels Clin. Chim. Acta 429 2014 76 78 10.1016/j.cca.2013.11.028 (Epub;%2013 Dec 4.:76-78)
    • (2014) Clin. Chim. Acta , vol.429 , pp. 76-78
    • Goncalves, L.H.1    Silva, M.V.2    Duarte, R.C.3    Dusse, L.M.4    Fernandes, A.P.5    Bosco, A.A.6    Gomes, K.B.7    Carvalho, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.