A Comparative Study of the T Cell Stimulatory and Polarizing Capacity of Human Primary Blood Dendritic Cell Subsets

Mediators of Inflammation

Volumn 2016, Issue , 2016, Pages

  Sittig, Simone P ^a   Bakdash, Ghaith ^a   Weiden, Jorieke ^a   Sköld, Annette E ^a,b   Tel, Jurjen ^a   Figdor, Carl G ^a   De Vries, I Jolanda M ^a   Schreibelt, Gerty ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CD1C ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 12; BLOOD DENDRITIC CELL ANTIGEN 3, HUMAN; CD1 ANTIGEN; CD1C PROTEIN, HUMAN; GLYCOPROTEIN; MEMBRANE ANTIGEN; TOLL LIKE RECEPTOR;

ARTICLE; CANCER IMMUNOTHERAPY; CD4+ T LYMPHOCYTE; CELL POLARITY; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; EFFECTOR CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOSTIMULATION; NORMAL HUMAN; PHENOTYPE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE; BONE MARROW CELL; CELL CULTURE; DRUG EFFECTS; IMMUNOLOGY; METABOLISM;

ANTIGENS, CD1; ANTIGENS, SURFACE; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; DENDRITIC CELLS; GLYCOPROTEINS; HUMANS; INTERLEUKIN-10; INTERLEUKIN-12; MYELOID CELLS; T-LYMPHOCYTES; TOLL-LIKE RECEPTORS;

EID: 84958999354     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2016/3605643     Document Type: Article

References (54)

1. R. M. Steinman, "The dendritic cell system and its role in immunogenicity," Annual Review of Immunology, vol. 9, pp. 271-296, 1991.
2. K. P. A. MacDonald, D. J. Munster, G. J. Clark, A. Dzionek, J. Schmitz, and D. N. J. Hart, "Characterization of human blood dendritic cell subsets," Blood, vol. 100, no. 13, pp. 4512-4520, 2002.
3. G. Schreibelt, J. Tel, K. H. E. W. J. Sliepen et al., "Toll-like receptor expression and function in human dendritic cell subsets: implications for dendritic cell-based anti-cancer immunotherapy," Cancer Immunology, Immunotherapy, vol. 59, no. 10, pp. 1573-1582, 2010.
4. M. Lindstedt, K. Lundberg, and C. A. K. Borrebaeck, "Gene family clustering identifies functionally associated subsets of human in vivo blood and tonsillar dendritic cells," Journal of Immunology, vol. 175, no. 8, pp. 4839-4846, 2005.
5. A. Dzionek, A. Fuchs, P. Schmidt et al., "BDCA-2, BDCA-3, and BDCA-4: three markers for distinct subsets of dendritic cells in human peripheral blood," The Journal of Immunology, vol. 165, no. 11, pp. 6037-6046, 2000.
6. D. Piccioli, S. Tavarini, E. Borgogni et al., "Functional specialization of human circulating CD16 and CD1c myeloid dendriticcell subsets," Blood, vol. 109, no. 12, pp. 5371-5379, 2007.
7. C. Hémont, A. Neel, M. Heslan, C. Braudeau, and R. Josien, "Human blood mDC subsets exhibit distinct TLR repertoire and responsiveness," Journal of Leukocyte Biology, vol. 93, no. 4, pp. 599-609, 2013.
8. M. Cella, D. Jarrossay, F. Faccheth et al., "Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon," Nature Medicine, vol. 5, no. 8, pp. 919-923, 1999.
9. T. S. M. Mathan, C. G. Figdor, and S. I. Buschow, "Human plasmacytoid dendritic cells: from molecules to intercellular communication network," Frontiers in Immunology, vol. 4, article 372, 2013.
10. M. Schnurr, Q. Chen, A. Shin et al., "Tumor antigen processing and presentation depend critically on dendritic cell type and the mode of antigen delivery," Blood, vol. 105, no. 6, pp. 2465-2472, 2005.
11. G. Hoeffel, A.-C. Ripoche, D. Matheoud et al., "Antigen crosspresentation by human plasmacytoid dendritic cells," Immunity, vol. 27, no. 3, pp. 481-492, 2007.
12. T. Di Pucchio, B. Chatterjee, A. Smed-Sörensen et al., "Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I," Nature Immunology, vol. 9, no. 5, pp. 551-557, 2008.
13. D. Mittag, A. I. Proietto, T. Loudovaris et al., "Human dendritic cell subsets from spleen and blood are similar in phenotype and function but modified by donor health status," Journal of Immunology, vol. 186, no. 11, pp. 6207-6217, 2011.
14. + T cells despite lower Ag uptake than myeloid dendritic cell subsets," Blood, vol. 121, no. 3, pp. 459-467, 2013.
15. E. Segura, M. Durand, and S. Amigorena, "Similar antigen cross-presentation capacity and phagocytic functions in all freshly isolated human lymphoid organ-resident dendritic cells," Journal of Experimental Medicine, vol. 210, no. 5, pp. 1035-1047, 2013.
16. G. Lui, O. Manches, J. Angel, J.-P. Molens, L. Chaperot, and J. Plumas, "Plasmacytoid dendritic cells capture and cross-present viral antigens from influenza-virus exposed cells," PLoS ONE, vol. 4, no. 9, Article ID e7111, 2009.
17. G. Schreibelt, K. F. Bol, H. Westdorp et al., "Effective clinical responses in metastatic melanoma patients after vaccination with primary myeloid dendritic cells," Clinical Cancer Research, 2015.
18. J. Tel, E. H. J. G. Aarntzen, T. Baba et al., "Natural human plasmacytoid dendritic cells induce antigen-specific T-cell responses in melanoma patients," Cancer Research, vol. 73, pp. 1063-1075, 2013.
19. G. T. Belz, W. R. Heath, and F. R. Carbone," The role of dendritic cell subsets in selection between tolerance and immunity," Immunology and Cell Biology, vol. 80, no. 5, pp. 463-468, 2002.
20. G. Trinchieri, "Interleukin-12 and its role in the generation of TH1 cells," Immunology Today, vol. 14,no. 7, pp. 335-338, 1993.
21. M. K. Levings, R. Sangregorio, F. Galbiati, S. Squadrone, R. De Waal Malefyt, and M.-G. Roncarolo, "IFN-α and IL-10 induce the differentiation of human type 1 t regulatory cells," The Journal of Immunology, vol. 166, no. 9, pp. 5530-5539, 2001.
22. T. L. Wagner, C. L. Ahonen, A. M. Couture et al., "Modulation of TH1 and TH2 cytokine production with the immune response modifiers, R-848 and imiquimod," Cellular Immunology, vol. 191, no. 1, pp. 10-19, 1999.
23. + Th1 immunity with poly IC as adjuvant," The Journal of Experimental Medicine, vol. 206, no. 7, pp. 1589-1602, 2009.
24. T. Jakob, P. S. Walker, A. M. Krieg, M. C. Udey, and J. C. Vogel, "Activation of cutaneous dendritic cells by Cp-Gcontaining oligodeoxynucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA," The Journal of Immunology, vol. 161, no. 6, pp. 3042-3049, 1998.
25. G. Napolitani, A. Rinaldi, F. Bertoni, F. Sallusto, and A. Lanzavecchia, "Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells," Nature Immunology, vol. 6, no. 8, pp. 769-776, 2005.
26. T. Ito, "Interferon-α and interleukin-12 are induced differentially by toll-like receptor 7 ligands in human blood dendritic cell subsets," The Journal of Experimental Medicine, vol. 195, no. 11, pp. 1507-1512, 2002.
27. + regulatory T cells," Human Vaccines and Immunotherapeutics, vol. 9, no. 2, pp. 250-258, 2013.
28. F. Brombacher, R. A. Kastelein, and G. Alber, "Novel IL-12 family members shed light on the orchestration of Th1 responses," Trends in Immunology, vol. 24, no. 4, pp. 207-212, 2003.
29. + dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses," Blood, vol. 122, no. 6, pp. 932-942, 2013.
30. O. Schulz, A. D. Edwards, M. Schitoetal., "CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal," Immunity, vol. 13, no. 4, pp. 453-462, 2000.
31. + dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens," Journal of Experimental Medicine, vol. 207, no. 6, pp. 1247-1260, 2010.
32. T. Ito, M. Yang, Y.-H. Wang et al., "Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligand," The Journal of Experimental Medicine, vol. 204, no. 1, pp. 105-115, 2007.
33. N. Kadowaki, S. Antonenko, J. Y.-N. Lau, and Y.-J. Liu, "Natural interferon α/β-producing cells link innate and adaptive immunity," The Journal of Experimental Medicine, vol. 192, no. 2, pp. 219-226, 2000.
34. + dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation," Journal of Experimental Medicine, vol. 209, no. 5, pp. 935-945, 2012.
35. + T cells to produce type 2 cytokines," Journal of Immunology, vol. 193, no. 9, pp. 4335-4343, 2014.
36. E. Segura, J. Valladeau-Guilemond, M.-H. Donnadieu, X. Sastre-Garau, V. Soumelis, and S. Amigorena, "Characterization of resident and migratory dendritic cells in human lymph nodes," Journal of Experimental Medicine, vol. 209, no. 4, pp. 653-660, 2012.
37. + DCs are major producers of IFN-λ in response to poly IC," The Journal of Experimental Medicine, vol. 207, no. 12, pp. 2703-2717, 2010.
38. R. P. Donnelly and S. V. Kotenko, "Interferon-lambda: a new addition to an old family," Journal of Interferon and Cytokine Research, vol. 30, no. 8, pp. 555-564, 2010.
39. M. Yoneyama, M. Kikuchi, T. Natsukawa et al., "The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses," Nature Immunology, vol. 5, no. 7, pp. 730-737, 2004.
40. H. Kato, O. Takeuchi, S. Sato et al., "Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses," Nature, vol. 441, no. 1, pp. 101-105, 2006.
41. I. Perrot, F. Deauvieau, C. Massacrier et al., "TLR3 and Rig-like receptor on myeloid dendritic cells and Rig-like receptor on human NK cells are both mandatory for production of IFN-γ in response to double-stranded RNA," Journal of Immunology, vol. 185, no. 4, pp. 2080-2088, 2010.
42. M. Kreutz, G. Bakdash, Y. Dolen et al., "Type I IFN-mediated synergistic activation of mouse and human DC subsets by TLR agonists," European Journal of Immunology, vol. 45, no. 10, pp. 2798-2809, 2015.
43. C. J. Montoya, H.-B. Jie, L. Al-Harthi et al., "Activation of plasmacytoid dendritic cells with TLR9 agonists initiates invariant NKT cell-mediated cross-talk with myeloid dendritic cells," The Journal of Immunology, vol. 177, no. 2, pp. 1028-1039, 2006.
44. C. Liu, Y. Lou, G. Lizée et al., "Plasmacytoid dendritic cells induce NK cell-dependent, tumor antigen-specific T cell cross-priming and tumor regression in mice," The Journal of Clinical Investigation, vol. 118, no. 3, pp. 1165-1175, 2008.
45. J. M. Curtsinger, J. O. Valenzuela, P. Agarwal, D. Lins, and M. F. Mescher, "Cutting edge: type I IFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation," The Journal of Immunology, vol. 174, no. 8, pp. 4465-4469, 2005.
46. E. L. Pearce and H. Shen, "Generation of CD8 T cell memory is regulated by IL-12," The Journal of Immunology, vol. 179, no. 4, pp. 2074-2081, 2007.
47. + dendritic cells," The Journal of Experimental Medicine, vol. 207, no. 6, pp. 1273-1281, 2010.
48. + dendritic cells," The Journal of Experimental Medicine, vol. 207, no. 6, pp. 1283-1292, 2010.
49. + nonlymphoid dendritic cells," Immunity, vol. 37, no. 1, pp. 60-73, 2012.
50. + leukocytes as putative equivalents of mouse CD8α+ dendritic cells," The Journal of Experimental Medicine, vol. 207, no. 6, pp. 1261-1271, 2010.
51. + dendritic cells at cross presentation," Journal of Experimental Medicine, vol. 210, no. 5, pp. 1049-1063, 2013.
52. + human dendritic cell function and development," Seminars in Cell & Developmental Biology, vol. 41, pp. 39-48, 2015.
53. T.-P. Vu Manh, N. Bertho, and A. Hosmalin, "Investigating evolutionary conservation of dendritic cell subset identity and functions," Frontiers in Immunology, vol. 6, article 260, 2015.
54. G. Bakdash, I. Schreurs, G. Schreibelt, and J. Tel, "Crosstalk between dendritic cell subsets and implications for dendritic cell-based anticancer immunotherapy," Expert Review of Clinical Immunology, vol. 10, no. 7, pp. 915-926, 2014.