TLR3 and Rig-like receptor on myeloid dendritic cells and Rig-like receptor on human NK cells are both mandatory for production of IFN-γ in response to double-stranded RNA

Journal of Immunology

Volumn 185, Issue 4, 2010, Pages 2080-2088

  Perrot, Ivan ^a   Deauvieau, Florence ^c   Massacrier, Catherine ^a   Hughes, Nicola ^a   Garrone, Pierre ^d   Durand, Isabelle ^c   Demaria, Olivier ^b   Viaud, Nicolas ^a   Gauthier, Laurent ^a   Blery, Mathieu ^a   Bonnefoy Berard, Nathalie ^c   Morel, Yannis ^a   Tschopp, Jurg ^e   Alexopoulou, Lena ^b   Trinchieri, Giorgio ^f   Paturel, Carine ^a   Caux, Christophe ^c  

^a INNATE PHARMA   (France)

^b CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^c INSERM   (France)

^d Epixis   (France)

^e UNIVERSITY OF LAUSANNE   (Switzerland)

^f NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED RNA; GAMMA INTERFERON; INTERFERON; INTERLEUKIN 12; LYMPHOCYTE ANTIGEN; POLYADENYLIC POLYURIDYLIC ACID; RIG LIKE RECEPTOR; TOLL LIKE RECEPTOR 3; UNCLASSIFIED DRUG; DDX58 PROTEIN, HUMAN; DDX58 PROTEIN, MOUSE; DEAD BOX PROTEIN; IFIH1 PROTEIN, HUMAN; IPS 1 PROTEIN, MOUSE; IPS-1 PROTEIN, MOUSE; POLYINOSINIC POLYCYTIDYLIC ACID; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN CELL; MOUSE; MYELOID DENDRITIC CELL; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; ANIMAL; BONE MARROW CELL; C57BL MOUSE; CELL CULTURE; CELL LINE; CYTOLOGY; DENDRITIC CELL; DOSE RESPONSE; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE MUTANT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL LINE; CELLS, CULTURED; DEAD-BOX RNA HELICASES; DENDRITIC CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INTERFERON-GAMMA; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID CELLS; POLY A-U; POLY I-C; RNA, DOUBLE-STRANDED; TOLL-LIKE RECEPTOR 3; TRANSFECTION;

EID: 77956928890     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1000532     Document Type: Article

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