메뉴 건너뛰기




Volumn 7, Issue 2, 2016, Pages 186-197

Bioengineering of noncoding RNAs for research agents and therapeutics

Author keywords

[No Author keywords available]

Indexed keywords

BIOENGINEERED NCRNA AGENT; OPTIMAL NCRNA SCAFFOLD; RECOMBINANT RNA; RIBOSOME RNA; RNA BINDING PROTEIN; SMALL INTERFERING RNA; TRANSFER RNA; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

EID: 84958943246     PISSN: 17577004     EISSN: 17577012     Source Type: Journal    
DOI: 10.1002/wrna.1324     Document Type: Review
Times cited : (59)

References (69)
  • 1
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros V. The functions of animal microRNAs. Nature 2004, 431:350-355.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 2
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: target recognition and regulatory functions
    • Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009, 136:215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 3
    • 85027935448 scopus 로고    scopus 로고
    • Small noncoding RNAs and male infertility
    • Gou LT, Dai P, Liu MF. Small noncoding RNAs and male infertility. WIREs RNA 2014, 5:733-745.
    • (2014) WIREs RNA , vol.5 , pp. 733-745
    • Gou, L.T.1    Dai, P.2    Liu, M.F.3
  • 4
    • 84857777210 scopus 로고    scopus 로고
    • Biogenesis and function of endogenous and exogenous siRNAs
    • Snead NM, Rossi JJ. Biogenesis and function of endogenous and exogenous siRNAs. WIREs RNA 2010, 1:117-131.
    • (2010) WIREs RNA , vol.1 , pp. 117-131
    • Snead, N.M.1    Rossi, J.J.2
  • 5
    • 84902533403 scopus 로고    scopus 로고
    • MicroRNAs as therapeutic targets in human cancers
    • Shah MY, Calin GA. MicroRNAs as therapeutic targets in human cancers. WIREs RNA 2014, 5:537-548.
    • (2014) WIREs RNA , vol.5 , pp. 537-548
    • Shah, M.Y.1    Calin, G.A.2
  • 7
    • 84869219338 scopus 로고    scopus 로고
    • miR-34 - a microRNA replacement therapy is headed to the clinic
    • Bader AG. miR-34 - a microRNA replacement therapy is headed to the clinic. Front Genet 2012, 3:120.
    • (2012) Front Genet , vol.3 , pp. 120
    • Bader, A.G.1
  • 8
    • 0032175927 scopus 로고    scopus 로고
    • Fomivirsen approved for CMV retinitis
    • Roehr B. Fomivirsen approved for CMV retinitis. J Int Assoc Physicians AIDS Care 1998, 4:14-16.
    • (1998) J Int Assoc Physicians AIDS Care , vol.4 , pp. 14-16
    • Roehr, B.1
  • 9
    • 33646232502 scopus 로고    scopus 로고
    • Safety and efficacy of two dose formulations of alicaforsen enema compared with mesalazine enema for treatment of mild to moderate left-sided ulcerative colitis: a randomized, double-blind, active-controlled trial
    • Miner PB Jr, Wedel MK, Xia S, Baker BF. Safety and efficacy of two dose formulations of alicaforsen enema compared with mesalazine enema for treatment of mild to moderate left-sided ulcerative colitis: a randomized, double-blind, active-controlled trial. Aliment Pharmacol Ther 2006, 23:1403-1413.
    • (2006) Aliment Pharmacol Ther , vol.23 , pp. 1403-1413
    • Miner, P.B.1    Wedel, M.K.2    Xia, S.3    Baker, B.F.4
  • 10
    • 84883787786 scopus 로고    scopus 로고
    • Two new drugs for homozygous familial hypercholesterolemia: managing benefits and risks in a rare disorder
    • Smith RJ, Hiatt WR. Two new drugs for homozygous familial hypercholesterolemia: managing benefits and risks in a rare disorder. JAMA Intern Med 2013, 173:1491-1492.
    • (2013) JAMA Intern Med , vol.173 , pp. 1491-1492
    • Smith, R.J.1    Hiatt, W.R.2
  • 13
    • 84892741671 scopus 로고    scopus 로고
    • Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial
    • Fitzgerald K, Frank-Kamenetsky M, Shulga-Morskaya S, Liebow A, Bettencourt BR, Sutherland JE, Hutabarat RM, Clausen VA, Karsten V, Cehelsky J, et al. Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial. Lancet 2014, 383:60-68.
    • (2014) Lancet , vol.383 , pp. 60-68
    • Fitzgerald, K.1    Frank-Kamenetsky, M.2    Shulga-Morskaya, S.3    Liebow, A.4    Bettencourt, B.R.5    Sutherland, J.E.6    Hutabarat, R.M.7    Clausen, V.A.8    Karsten, V.9    Cehelsky, J.10
  • 14
    • 84922431782 scopus 로고    scopus 로고
    • Turning mirror-image oligonucleotides into drugs: the evolution of Spiegelmer((R)) therapeutics
    • Vater A, Klussmann S. Turning mirror-image oligonucleotides into drugs: the evolution of Spiegelmer((R)) therapeutics. Drug Discov Today 2015, 20:147-155.
    • (2015) Drug Discov Today , vol.20 , pp. 147-155
    • Vater, A.1    Klussmann, S.2
  • 16
    • 84922273505 scopus 로고    scopus 로고
    • In vivo delivery of miRNAs for cancer therapy: challenges and strategies
    • Chen Y, Gao DY, Huang L. In vivo delivery of miRNAs for cancer therapy: challenges and strategies. Adv Drug Deliv Rev 2015, 81:128-141.
    • (2015) Adv Drug Deliv Rev , vol.81 , pp. 128-141
    • Chen, Y.1    Gao, D.Y.2    Huang, L.3
  • 18
    • 2942558637 scopus 로고    scopus 로고
    • Recent advances in the high-speed solid phase synthesis of RNA
    • Marshall WS, Kaiser RJ. Recent advances in the high-speed solid phase synthesis of RNA. Curr Opin Chem Biol 2004, 8:222-229.
    • (2004) Curr Opin Chem Biol , vol.8 , pp. 222-229
    • Marshall, W.S.1    Kaiser, R.J.2
  • 19
    • 0023651444 scopus 로고
    • Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates
    • Milligan J, Groebe D, Witherell G, Uhlenbeck O. Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates. Nucleic Acids Res 1987, 15:8783-8798.
    • (1987) Nucleic Acids Res , vol.15 , pp. 8783-8798
    • Milligan, J.1    Groebe, D.2    Witherell, G.3    Uhlenbeck, O.4
  • 20
    • 79952599664 scopus 로고    scopus 로고
    • Synthesis of RNA by in vitro transcription
    • Beckert B, Masquida B. Synthesis of RNA by in vitro transcription. Methods Mol Biol 2011, 703:29-41.
    • (2011) Methods Mol Biol , vol.703 , pp. 29-41
    • Beckert, B.1    Masquida, B.2
  • 21
    • 66749152587 scopus 로고    scopus 로고
    • A generic protocol for the expression and purification of recombinant RNA in Escherichia coli using a tRNA scaffold
    • Ponchon L, Beauvais G, Nonin-Lecomte S, Dardel F. A generic protocol for the expression and purification of recombinant RNA in Escherichia coli using a tRNA scaffold. Nat Protoc 2009, 4:947-959.
    • (2009) Nat Protoc , vol.4 , pp. 947-959
    • Ponchon, L.1    Beauvais, G.2    Nonin-Lecomte, S.3    Dardel, F.4
  • 22
    • 34547659860 scopus 로고    scopus 로고
    • Recombinant RNA technology: the tRNA scaffold
    • Ponchon L, Dardel F. Recombinant RNA technology: the tRNA scaffold. Nat Methods 2007, 4:571-576.
    • (2007) Nat Methods , vol.4 , pp. 571-576
    • Ponchon, L.1    Dardel, F.2
  • 23
    • 77955289619 scopus 로고    scopus 로고
    • DNAzyme-mediated recovery of small recombinant RNAs from a 5S rRNA-derived chimera expressed in Escherichia coli
    • Liu Y, Stepanov VG, Strych U, Willson RC, Jackson GW, Fox GE. DNAzyme-mediated recovery of small recombinant RNAs from a 5S rRNA-derived chimera expressed in Escherichia coli. BMC Biotechnol 2010, 10:85.
    • (2010) BMC Biotechnol , vol.10 , pp. 85
    • Liu, Y.1    Stepanov, V.G.2    Strych, U.3    Willson, R.C.4    Jackson, G.W.5    Fox, G.E.6
  • 24
    • 84930505521 scopus 로고    scopus 로고
    • A general approach to high-yield biosynthesis of chimeric RNAs bearing various types of functional small RNAs for broad applications
    • Chen QX, Wang WP, Zeng S, Urayama S, Yu AM. A general approach to high-yield biosynthesis of chimeric RNAs bearing various types of functional small RNAs for broad applications. Nucleic Acids Res 2015, 43:3857-3869.
    • (2015) Nucleic Acids Res , vol.43 , pp. 3857-3869
    • Chen, Q.X.1    Wang, W.P.2    Zeng, S.3    Urayama, S.4    Yu, A.M.5
  • 25
    • 84941555844 scopus 로고    scopus 로고
    • Bioengineering novel chimeric microRNA-34a for prodrug cancer therapy: high-yield expression and purification, and structural and functional characterization
    • Wang WP, Ho PY, Chen QX, Addepalli B, Limbach PA, Li MM, Wu WJ, Jilek JL, Qiu JX, Zhang HJ, et al. Bioengineering novel chimeric microRNA-34a for prodrug cancer therapy: high-yield expression and purification, and structural and functional characterization. J Pharmacol Exp Ther 2015, 354:131-141.
    • (2015) J Pharmacol Exp Ther , vol.354 , pp. 131-141
    • Wang, W.P.1    Ho, P.Y.2    Chen, Q.X.3    Addepalli, B.4    Limbach, P.A.5    Li, M.M.6    Wu, W.J.7    Jilek, J.L.8    Qiu, J.X.9    Zhang, H.J.10
  • 26
    • 84856389509 scopus 로고    scopus 로고
    • RNA-based therapeutics: current progress and future prospects
    • Burnett JC, Rossi JJ. RNA-based therapeutics: current progress and future prospects. Chem Biol 2012, 19:60-71.
    • (2012) Chem Biol , vol.19 , pp. 60-71
    • Burnett, J.C.1    Rossi, J.J.2
  • 27
    • 77949512140 scopus 로고    scopus 로고
    • RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform
    • Bennett CF, Swayze EE. RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform. Annu Rev Pharmacol Toxicol 2010, 50:259-293.
    • (2010) Annu Rev Pharmacol Toxicol , vol.50 , pp. 259-293
    • Bennett, C.F.1    Swayze, E.E.2
  • 28
    • 84856402483 scopus 로고    scopus 로고
    • A status update of modified oligonucleotides for chemotherapeutics applications
    • Chapter 4: Unit 4:1-22.
    • Sanghvi YS. Chapter 4: A status update of modified oligonucleotides for chemotherapeutics applications. In: Current Protocols in Nucleic Acids Chemistry. 2011, Unit 4:1-22.
    • (2011) Current Protocols in Nucleic Acids Chemistry
    • Sanghvi, Y.S.1
  • 29
    • 77249096959 scopus 로고    scopus 로고
    • Exploring chemical modifications for siRNA therapeutics: a structural and functional outlook
    • Shukla S, Sumaria CS, Pradeepkumar PI. Exploring chemical modifications for siRNA therapeutics: a structural and functional outlook. ChemMedChem 2010, 5:328-349.
    • (2010) ChemMedChem , vol.5 , pp. 328-349
    • Shukla, S.1    Sumaria, C.S.2    Pradeepkumar, P.I.3
  • 30
    • 34250777057 scopus 로고    scopus 로고
    • Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections
    • Obernosterer G, Martinez J, Alenius M. Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections. Nat Protoc 2007, 2:1508-1514.
    • (2007) Nat Protoc , vol.2 , pp. 1508-1514
    • Obernosterer, G.1    Martinez, J.2    Alenius, M.3
  • 35
    • 32644447756 scopus 로고    scopus 로고
    • Post-transcriptional nucleotide modification and alternative folding of RNA
    • Helm M. Post-transcriptional nucleotide modification and alternative folding of RNA. Nucleic Acids Res 2006, 34:721-733.
    • (2006) Nucleic Acids Res , vol.34 , pp. 721-733
    • Helm, M.1
  • 37
    • 34548431318 scopus 로고    scopus 로고
    • Naturally occurring nucleoside modifications suppress the immunostimulatory activity of RNA: Implication for therapeutic RNA development
    • Kariko K, Weissman D. Naturally occurring nucleoside modifications suppress the immunostimulatory activity of RNA: Implication for therapeutic RNA development. Curr Opin Drug Discov Dev 2007, 10:523-532.
    • (2007) Curr Opin Drug Discov Dev , vol.10 , pp. 523-532
    • Kariko, K.1    Weissman, D.2
  • 38
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
    • Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 2001, 413:732-738.
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 39
    • 1542317550 scopus 로고    scopus 로고
    • Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
    • Diebold SS, Kaisho T, Hemmi H, Akira S, Reis e Sousa C. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 2004, 303:1529-1531.
    • (2004) Science , vol.303 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3    Akira, S.4    Reis e Sousa, C.5
  • 41
    • 23844464444 scopus 로고    scopus 로고
    • Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA
    • Kariko K, Buckstein M, Ni H, Weissman D. Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA. Immunity 2005, 23:165-175.
    • (2005) Immunity , vol.23 , pp. 165-175
    • Kariko, K.1    Buckstein, M.2    Ni, H.3    Weissman, D.4
  • 42
    • 84877261475 scopus 로고    scopus 로고
    • Efficient and specific gene knockdown by small interfering RNAs produced in bacteria
    • Huang L, Jin J, Deighan P, Kiner E, McReynolds L, Lieberman J. Efficient and specific gene knockdown by small interfering RNAs produced in bacteria. Nat Biotechnol 2013, 31:350-356.
    • (2013) Nat Biotechnol , vol.31 , pp. 350-356
    • Huang, L.1    Jin, J.2    Deighan, P.3    Kiner, E.4    McReynolds, L.5    Lieberman, J.6
  • 44
    • 84940387756 scopus 로고    scopus 로고
    • Chimeric microRNA-1291 biosynthesized efficiently in Escherichia coli is effective to reduce target gene expression in human carcinoma cells and improve chemosensitivity
    • Li MM, Addepalli B, Tu MJ, Chen QX, Wang WP, Limbach PA, LaSalle JM, Zeng S, Huang M, Yu AM. Chimeric microRNA-1291 biosynthesized efficiently in Escherichia coli is effective to reduce target gene expression in human carcinoma cells and improve chemosensitivity. Drug Metab Dispos 2015, 43:1129-1136.
    • (2015) Drug Metab Dispos , vol.43 , pp. 1129-1136
    • Li, M.M.1    Addepalli, B.2    Tu, M.J.3    Chen, Q.X.4    Wang, W.P.5    Limbach, P.A.6    LaSalle, J.M.7    Zeng, S.8    Huang, M.9    Yu, A.M.10
  • 45
    • 0031686310 scopus 로고    scopus 로고
    • T7 RNA polymerase produces 5′ end heterogeneity during in vitro transcription from certain templates
    • Pleiss JA, Derrick ML, Uhlenbeck O. T7 RNA polymerase produces 5′ end heterogeneity during in vitro transcription from certain templates. RNA 1998, 4:1313-1317.
    • (1998) RNA , vol.4 , pp. 1313-1317
    • Pleiss, J.A.1    Derrick, M.L.2    Uhlenbeck, O.3
  • 46
    • 0030995087 scopus 로고    scopus 로고
    • Initiation, elongation, and processivity of carboxyl-terminal mutants of T7 RNA polymerase
    • Gardner LP, Mookhtiar KA, Coleman JE. Initiation, elongation, and processivity of carboxyl-terminal mutants of T7 RNA polymerase. Biochemistry 1997, 36:2908-2918.
    • (1997) Biochemistry , vol.36 , pp. 2908-2918
    • Gardner, L.P.1    Mookhtiar, K.A.2    Coleman, J.E.3
  • 47
    • 84930221688 scopus 로고    scopus 로고
    • RNA editing by T7 RNA polymerase bypasses InDel mutations causing unexpected phenotypic changes
    • Wons E, Furmanek-Blaszk B, Sektas M. RNA editing by T7 RNA polymerase bypasses InDel mutations causing unexpected phenotypic changes. Nucleic Acids Res 2015, 43:3950-3963.
    • (2015) Nucleic Acids Res , vol.43 , pp. 3950-3963
    • Wons, E.1    Furmanek-Blaszk, B.2    Sektas, M.3
  • 48
    • 0037162522 scopus 로고    scopus 로고
    • Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells
    • Yang D, Buchholz F, Huang Z, Goga A, Chen CY, Brodsky FM, Bishop JM. Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells. Proc Natl Acad Sci USA 2002, 99:9942-9947.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 9942-9947
    • Yang, D.1    Buchholz, F.2    Huang, Z.3    Goga, A.4    Chen, C.Y.5    Brodsky, F.M.6    Bishop, J.M.7
  • 49
    • 0033789992 scopus 로고    scopus 로고
    • Specific interference with gene function by double-stranded RNA in early mouse development
    • Wianny F, Zernicka-Goetz M. Specific interference with gene function by double-stranded RNA in early mouse development. Nat Cell Biol 2000, 2:70-75.
    • (2000) Nat Cell Biol , vol.2 , pp. 70-75
    • Wianny, F.1    Zernicka-Goetz, M.2
  • 50
    • 0037335550 scopus 로고    scopus 로고
    • Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing
    • Myers JW, Jones JT, Meyer T, Ferrell JE Jr. Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing. Nat Biotechnol 2003, 21:324-328.
    • (2003) Nat Biotechnol , vol.21 , pp. 324-328
    • Myers, J.W.1    Jones, J.T.2    Meyer, T.3    Ferrell, J.E.4
  • 51
  • 52
    • 0035987113 scopus 로고    scopus 로고
    • Tombusvirus P19-mediated suppression of virus-induced gene silencing is controlled by genetic and dosage features that influence pathogenicity
    • Qiu W, Park JW, Scholthof HB. Tombusvirus P19-mediated suppression of virus-induced gene silencing is controlled by genetic and dosage features that influence pathogenicity. Mol Plant Microbe Interact 2002, 15:269-280.
    • (2002) Mol Plant Microbe Interact , vol.15 , pp. 269-280
    • Qiu, W.1    Park, J.W.2    Scholthof, H.B.3
  • 53
    • 0037124354 scopus 로고    scopus 로고
    • A viral protein suppresses RNA silencing and binds silencing-generated, 21- to 25-nucleotide double-stranded RNAs
    • Silhavy D, Molnar A, Lucioli A, Szittya G, Hornyik C, Tavazza M, Burgyan J. A viral protein suppresses RNA silencing and binds silencing-generated, 21- to 25-nucleotide double-stranded RNAs. EMBO J 2002, 21:3070-3080.
    • (2002) EMBO J , vol.21 , pp. 3070-3080
    • Silhavy, D.1    Molnar, A.2    Lucioli, A.3    Szittya, G.4    Hornyik, C.5    Tavazza, M.6    Burgyan, J.7
  • 54
    • 77954128549 scopus 로고    scopus 로고
    • Protein mediated miRNA detection and siRNA enrichment using p19
    • Jin J, Cid M, Poole CB, McReynolds LA. Protein mediated miRNA detection and siRNA enrichment using p19. Biotechniques 2010, 48:xvii-xxiii.
    • (2010) Biotechniques , vol.48 , pp. 17-23
    • Jin, J.1    Cid, M.2    Poole, C.B.3    McReynolds, L.A.4
  • 55
    • 77956276464 scopus 로고    scopus 로고
    • tRNA biology charges to the front
    • Phizicky EM, Hopper AK. tRNA biology charges to the front. Genes Dev 2010, 24:1832-1860.
    • (2010) Genes Dev , vol.24 , pp. 1832-1860
    • Phizicky, E.M.1    Hopper, A.K.2
  • 56
    • 84931292139 scopus 로고    scopus 로고
    • RoboOligo: software for mass spectrometry data to support manual and de novo sequencing of post-transcriptionally modified ribonucleic acids
    • Sample PJ, Gaston KW, Alfonzo JD, Limbach PA. RoboOligo: software for mass spectrometry data to support manual and de novo sequencing of post-transcriptionally modified ribonucleic acids. Nucleic Acids Res 2015, 43:e64.
    • (2015) Nucleic Acids Res , vol.43
    • Sample, P.J.1    Gaston, K.W.2    Alfonzo, J.D.3    Limbach, P.A.4
  • 57
    • 84871436566 scopus 로고    scopus 로고
    • Transfer RNA modifications: nature's combinatorial chemistry playground
    • Jackman JE, Alfonzo JD. Transfer RNA modifications: nature's combinatorial chemistry playground. WIREs RNA 2013, 4:35-48.
    • (2013) WIREs RNA , vol.4 , pp. 35-48
    • Jackman, J.E.1    Alfonzo, J.D.2
  • 58
    • 30744466880 scopus 로고    scopus 로고
    • Modified view of tRNA: stability amid sequence diversity
    • Engelke DR, Hopper AK. Modified view of tRNA: stability amid sequence diversity. Mol Cell 2006, 21:144-145.
    • (2006) Mol Cell , vol.21 , pp. 144-145
    • Engelke, D.R.1    Hopper, A.K.2
  • 59
    • 0023695894 scopus 로고
    • Fast purification of a functional elongator tRNAmet expressed from a synthetic gene in vivo
    • Meinnel T, Mechulam Y, Fayat G. Fast purification of a functional elongator tRNAmet expressed from a synthetic gene in vivo. Nucleic Acids Res 1988, 16:8095-8096.
    • (1988) Nucleic Acids Res , vol.16 , pp. 8095-8096
    • Meinnel, T.1    Mechulam, Y.2    Fayat, G.3
  • 60
    • 0042349572 scopus 로고    scopus 로고
    • The tRNA-like domains of E. coli and A. aeolicus transfer-messenger RNA: structural and functional studies
    • Gaudin C, Nonin-Lecomte S, Tisné C, Corvaisier S, Bordeau V, Dardel F, Felden B. The tRNA-like domains of E. coli and A. aeolicus transfer-messenger RNA: structural and functional studies. J Mol Biol 2003, 331:457-471.
    • (2003) J Mol Biol , vol.331 , pp. 457-471
    • Gaudin, C.1    Nonin-Lecomte, S.2    Tisné, C.3    Corvaisier, S.4    Bordeau, V.5    Dardel, F.6    Felden, B.7
  • 61
    • 79960959180 scopus 로고    scopus 로고
    • RNA mimics of green fluorescent protein
    • Paige JS, Wu KY, Jaffrey SR. RNA mimics of green fluorescent protein. Science 2011, 333:642-646.
    • (2011) Science , vol.333 , pp. 642-646
    • Paige, J.S.1    Wu, K.Y.2    Jaffrey, S.R.3
  • 62
    • 84858030373 scopus 로고    scopus 로고
    • Fluorescence imaging of cellular metabolites with RNA
    • Paige JS, Nguyen-Duc T, Song W, Jaffrey SR. Fluorescence imaging of cellular metabolites with RNA. Science 2012, 335:1194.
    • (2012) Science , vol.335 , pp. 1194
    • Paige, J.S.1    Nguyen-Duc, T.2    Song, W.3    Jaffrey, S.R.4
  • 64
    • 84907917954 scopus 로고    scopus 로고
    • Rapid production of novel pre-microRNA agent hsa-mir-27b in Escherichia coli using recombinant RNA technology for functional studies in mammalian cells
    • Li MM, Wang WP, Wu WJ, Huang M, Yu AM. Rapid production of novel pre-microRNA agent hsa-mir-27b in Escherichia coli using recombinant RNA technology for functional studies in mammalian cells. Drug Metab Dispos 2014, 42:1791-1795.
    • (2014) Drug Metab Dispos , vol.42 , pp. 1791-1795
    • Li, M.M.1    Wang, W.P.2    Wu, W.J.3    Huang, M.4    Yu, A.M.5
  • 66
    • 0028883652 scopus 로고
    • A novel approach for monitoring genetically engineered microorganisms by using artificial, stable RNAs
    • Pitulle C, Hedenstierna KO, Fox GE. A novel approach for monitoring genetically engineered microorganisms by using artificial, stable RNAs. Appl Environ Microbiol 1995, 61:3661-3666.
    • (1995) Appl Environ Microbiol , vol.61 , pp. 3661-3666
    • Pitulle, C.1    Hedenstierna, K.O.2    Fox, G.E.3
  • 67
    • 0029762958 scopus 로고    scopus 로고
    • Useful properties of restriction enzymes that recognize interrupted palindromes
    • 622.
    • Pitulle C, Hedenstierna KO, Fox GE. Useful properties of restriction enzymes that recognize interrupted palindromes. Biotechniques 1996, 21:619-620, 622.
    • (1996) Biotechniques , vol.21 , pp. 619-620
    • Pitulle, C.1    Hedenstierna, K.O.2    Fox, G.E.3
  • 68
    • 0031052173 scopus 로고    scopus 로고
    • A low molecular weight artificial RNA of unique size with multiple probe target regions
    • Pitulle C, Dsouza L, Fox GE. A low molecular weight artificial RNA of unique size with multiple probe target regions. Syst Appl Microbiol 1997, 20:133-136.
    • (1997) Syst Appl Microbiol , vol.20 , pp. 133-136
    • Pitulle, C.1    Dsouza, L.2    Fox, G.E.3
  • 69
    • 84958837063 scopus 로고    scopus 로고
    • MicroRNA pharmacoepigenetics: Posttranscriptional regulation mechanisms behind variable drug disposition and strategy to develop more effective therapy
    • press.
    • Yu AM, Tian Y, Tu MJ, Ho PY, Jilek JL. MicroRNA pharmacoepigenetics: Posttranscriptional regulation mechanisms behind variable drug disposition and strategy to develop more effective therapy. Drug Metab Dispos. In press.
    • Drug Metab Dispos
    • Yu, A.M.1    Tian, Y.2    Tu, M.J.3    Ho, P.Y.4    Jilek, J.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.