Efficient and specific gene knockdown by small interfering RNAs produced in bacteria

Nature Biotechnology

Volumn 31, Issue 4, 2013, Pages 350-356

  Huang, Linfeng ^a,b   Jin, Jingmin ^c   Deighan, Padraig ^b,d   Kiner, Evgeny ^a,b   McReynolds, Larry ^c   Lieberman, Judy ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c NEW ENGLAND BIOLABS   (United States)

^d EMMANUEL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL SYNTHESIS; ECTOPIC EXPRESSIONS; EUKARYOTIC CELLS; GENE KNOCK DOWN; INDISPENSABLE TOOLS; MULTIPLE SEQUENCES; SMALL INTERFERING RNA; TARGET GENE EXPRESSION;

BACTERIA; ESCHERICHIA COLI; GENE ENCODING; GENE EXPRESSION; RNA; VIRUSES;

GENE THERAPY;

NUCLEOTIDE; PLANT RNA; PROTEIN P19; SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

ARTICLE; BACTERIAL GENE; ESCHERICHIA COLI; EUKARYOTIC CELL; GENE EXPRESSION; GENE FUNCTION; GENE SILENCING; GENE TARGETING; IMMUNOGENICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PLANT VIRUS; PRIORITY JOURNAL; PROTEIN STABILITY; REPRODUCIBILITY; RNA INTERFERENCE; RNA SEQUENCE; RNA VIRUS; VIRUS GENE;

BASE SEQUENCE; ESCHERICHIA COLI; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; GENES, BACTERIAL; HCT116 CELLS; HELA CELLS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MOLECULAR SEQUENCE DATA; RNA, BACTERIAL; RNA, SMALL INTERFERING; VIRAL CORE PROTEINS;

EID: 84877261475     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.2537     Document Type: Article

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