Cellular analysis of the histamine H4 receptor in human myeloid cells

Biochemical Pharmacology

Volumn 103, Issue , 2016, Pages 74-84

  Capelo, Ricardo ^a   Lehmann, Christoph ^b   Ahmad, Khalil ^a   Snodgrass, Ryan ^a   Diehl, Olaf ^a   Ringleb, Julia ^a   Flamand, Nicolas ^c   Weigert, Andreas ^a   Stark, Holger ^d   Steinhilber, Dieter ^a   Kahnt, Astrid S ^a  

^a GOETHE UNIVERSITY   (Germany)

^b FRAUNHOFER INSTITUTE FOR MOLECULAR BIOLOGY AND APPLIED ECOLOGY IME   (Germany)

^c LAVAL UNIVERSITY   (Canada)

^d HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Eosinophils; Histamine receptor; Inflammation; Macrophages; Monocytes

Indexed keywords

1 (5 CHLORO 2 INDOLYLCARBONYL) 4 METHYLPIPERAZINE; APICIDIN; CALCITRIOL; CALCIUM; COLONY STIMULATING FACTOR 1; DIPHENHYDRAMINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HISTAMINE H1 RECEPTOR; HISTAMINE H2 RECEPTOR; HISTAMINE H4 RECEPTOR; INTERLEUKIN 13; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; MESSENGER RNA; THAPSIGARGIN; TOLL LIKE RECEPTOR 3; ZYMOSAN; G PROTEIN COUPLED RECEPTOR; HISTAMINE RECEPTOR; HRH4 PROTEIN, HUMAN; INTERLEUKIN 3;

ARTICLE; BONE MARROW CELL; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL ACTIVATION; CELL DIFFERENTIATION; CONTROLLED STUDY; DENDRITIC CELL; DOWN REGULATION; EOSINOPHIL; GENE EXPRESSION; GRANULOCYTE; HUMAN; HUMAN CELL; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE; MAST CELL; MONOCYTE; POLARIZATION; PRIMARY CELL; PRIORITY JOURNAL; UPREGULATION; CELL LINE; CELL POLARITY; CYTOLOGY; DRUG EFFECTS; GENETICS; IMMUNOLOGY; MACROPHAGE ACTIVATION; METABOLISM; PRIMARY CELL CULTURE; TUMOR CELL LINE;

CALCIUM; CELL DIFFERENTIATION; CELL LINE; CELL LINE, TUMOR; CELL POLARITY; DENDRITIC CELLS; GRANULOCYTES; HUMANS; INTERLEUKIN-3; INTERLEUKIN-4; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MONOCYTES; MYELOID CELLS; PRIMARY CELL CULTURE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE; RECEPTORS, HISTAMINE H1; RECEPTORS, HISTAMINE H2; RNA, MESSENGER; ZYMOSAN;

EID: 84958852431     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2016.01.007     Document Type: Article

References (33)

1. P. Panula, P.L. Chazot, M. Cowart, R. Gutzmer, R. Leurs, W.L. Liu, and et al. International union of basic and clinical pharmacology. XCVIII. Histamine receptors Pharmacol. Rev. 67 3 2015 601 655
2. R. Seifert, A. Strasser, E.H. Schneider, D. Neumann, S. Dove, and A. Buschauer Molecular and cellular analysis of human histamine receptor subtypes Trends Pharmacol. Sci. 34 1 2013 33 58
3. R.L. Thurmond, E.W. Gelfand, and P.J. Dunford The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines Nat. Rev. Drug Discov. 7 1 2008 41 53
4. R.L. Thurmond, P.J. Desai, P.J. Dunford, W.P. Fung-Leung, C.L. Hofstra, W. Jiang, and et al. A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties J. Pharmacol. Exp. Ther. 309 1 2004 404 413
5. J.M. Cowden, F. Yu, H. Banie, M. Farahani, P. Ling, S. Nguyen, and et al. The histamine H4 receptor mediates inflammation and Th17 responses in preclinical models of arthritis Ann. Rheum. Dis. 73 3 2014 600 608
6. E. Nent, D. Frommholz, M. Gajda, R. Bräuer, H. Illges, and et al. Histamine 4 receptor plays an important role in auto-antibody-induced arthritis Int. Immunol. 25 7 2013 437 443
7. P.J. Dunford, N. O'Donnell, J.P. Riley, K.N. Williams, L. Karlsson, and R.L. Thurmond The histamine H4 receptor mediates allergic airway inflammation by regulating the activation of CD4+ T cells J. Immunol. 176 11 2006 7062 7070
8. K. Rossbach, C. Nassenstein, M. Gschwandtner, D. Schnell, K. Sander, R. Seifert, and et al. Histamine H1, H3 and H4 receptors are involved in pruritus Neuroscience 190 2011 89 102
9. R.K. Morgan, B. McAllister, L. Cross, D.S. Green, H. Kornfeld, D.M. Center, and et al. Histamine 4 receptor activation induces recruitment of FoxP3+ T cells and inhibits allergic asthma in a murine model J. Immunol. 178 12 2007 8081 8089
10. 4-receptor lack specificity Naunyn Schmiedebergs Arch. Pharmacol. 385 2 2012 125 135
11. M. Grosicki, and K. Kiec-Kononowicz Human eosinophils - potential pharmacological model applied in human histamine h4 receptor research Curr. Med. Chem. 22 17 2015 2087 2099
12. O. Werz, M. Brungs, and D. Steinhilber Purification of transforming growth factor beta 1 from human platelets Pharmazie 51 11 1996 893 896
13. F. Gerosa, B. Baldani-Guerra, L.A. Lyakh, G. Batoni, S. Esin, R.T. Winkler-Pickett, and et al. Differential regulation of interleukin 12 and interleukin 23 production in human dendritic cells J. Exp. Med. 205 6 2008 1447 1461
14. A. Ariel, and C.N. Serhan New lives given by cell death: macrophage differentiation following their encounter with apoptotic leukocytes during the resolution of inflammation Front. Immunol. 3 2012 4
15. K. Ishihara, A. Takahashi, M. Kaneko, H. Sugeno, N. Hirasawa, J. Hong, and et al. Differentiation of eosinophilic leukemia EoL-1 cells into eosinophils induced by histone deacetylase inhibitors Life Sci. 80 13 2007 1213 1220
16. H. Ohtsu, K. Yamauchi, O. Yoshie, Y. Tanno, H. Saito, N. Hayashi, and et al. The effect of cytokines on the differentiation of an eosinophilic leukemia cell line (EoL-1) is associated with down regulation of c-myc gene expression Cell Struct. Funct. 18 2 1993 125 133
17. T.M. Reher, I. Brunskole, D. Neumann, and R. Seifert Evidence for ligand-specific conformations of the histamine H(2)-receptor in human eosinophils and neutrophils Biochem. Pharmacol. 84 9 2012 1174 1185
18. T.M. Reher, D. Neumann, A. Buschauer, and R. Seifert Incomplete activation of human eosinophils via the histamine H4-receptor: evidence for ligand-specific receptor conformations Biochem. Pharmacol. 84 2 2012 192 203
19. K. Werner, D. Neumann, A. Buschauer, R. Seifert, and et al. No evidence for histamine H4 receptor in human monocytes J. Pharmacol. Exp. Ther. 351 3 2014 519 526
20. D. Dijkstra, R. Leurs, P. Chazot, F.C. Shenton, H. Stark, T. Werfel, and et al. Histamine downregulates monocyte CCL2 production through the histamine H4 receptor J. Allergy Clin. Immunol. 120 2 2007 300 307
21. K. Dib, T. Perecko, V. Jenei, C. McFarlane, D. Comer, V. Brown, and et al. The histamine H4 receptor is a potent inhibitor of adhesion-dependent degranulation in human neutrophils J. Leukoc. Biol. 96 3 2014 411 418
22. R. Gutzmer, S. Mommert, M. Gschwandtner, K. Zwingmann, H. Stark, and T. Werfel The histamine H4 receptor is functionally expressed on T(H)2 cells J. Allergy Clin. Immunol. 123 3 2009 619 625
23. N. Matsuda, H. Teramae, M. Futatsugi, K. Takano, S. Yamamoto, K. Tomita, and et al. Up-regulation of histamine H4 receptors contributes to splenic apoptosis in septic mice: counteraction of the antiapoptotic action of nuclear factor-kappaB J. Pharmacol. Exp. Ther. 332 3 2010 730 737
24. M. Ciebiada, K. Kasztalska, M. Gorska-Ciebiada, and P. Górski Histamine type 2 receptor expression on peripheral blood regulatory lymphocytes in patients with allergic rhinitis treated with specific immunotherapy Am. J. Rhinol. Allergy 28 3 2014 e130 e135
25. M. Kaneko, K. Ishihara, A. Takahashi, J. Hong, N. Hirasawa, O. Zee, and et al. Mechanism for the differentiation of EoL-1 cells into eosinophils by histone deacetylase inhibitors Int. Arch. Allergy Immunol. 143 Suppl. 1 2007 28 32
26. M. Triggiani, A. Petraroli, S. Loffredo, A. Frattini, F. Granata, P. Morabito, and et al. Differentiation of monocytes into macrophages induces the upregulation of histamine H1 receptor J. Allergy Clin. Immunol. 119 2 2007 472 481
27. K.Y. Wang, N. Arima, S. Higuchi, S. Shimajiri, A. Tanimoto, Y. Murata, and et al. Switch of histamine receptor expression from H2 to H1 during differentiation of monocytes into macrophages FEBS Lett. 473 3 2000 345 348
28. K. Werner, D. Neumann, and R. Seifert Analysis of the histamine H2-receptor in human monocytes Biochem. Pharmacol. 92 2 2014 369 379
29. M. Triggiani, M. Gentile, A. Secondo, F. Granata, A. Oriente, M. Taglialatela, and et al. Histamine induces exocytosis and IL-6 production from human lung macrophages through interaction with H1 receptors J. Immunol. 166 6 2001 4083 4091
30. Y. Ogawa, Y. Ichinokawa, M. Hiruma, Y. Machida, N. Funakushi, H. Sadamasa, and et al. Retrospective cohort study on combination therapy with the histamine H2-receptor antagonist lafutidine for antihistamine-resistant chronic urticaria J. Dermatol. Treat. 24 6 2013 463 465
31. G. Caron, Y. Delneste, E. Roelandts, C. Duez, J.Y. Bonnefoy, J. Pestel, and et al. Histamine polarizes human dendritic cells into Th2 cell-promoting effector dendritic cells J. Immunol. 167 7 2001 3682 3686
32. 4 receptor antagonist, JNJ 39758979, is effective in reducing histamine-induced pruritus in a randomized clinical study in healthy subjects J. Pharmacol. Exp. Ther. 350 1 2014 181 187
33. Y. Murata, M. Song, H. Kikuchi, K. Hisamichi, X.L. Xu, A. Greenspan, and et al. Phase 2a, randomized, double-blind, placebo-controlled, multicenter, parallel-group study of a H4 R-antagonist (JNJ-39758979) in Japanese adults with moderate atopic dermatitis J. Dermatol. 42 2 2015 129 139