Histamine 4 receptor plays an important role in auto-antibody-induced arthritis

International Immunology

Volumn 25, Issue 7, 2013, Pages 437-443

  Nent, Elisa ^a   Frommholz, David ^a   Gajda, Mieczyslaw ^b   Bräuer, Rolf ^b   Illges, Harald ^a  

^a UNIVERSITY OF APPLIED SCIENCES   (Germany)

^b JENA UNIVERSITY HOSPITAL   (Germany)

Author keywords

Autoimmune disease; Histamine receptor antagonist; K B N model

Indexed keywords

AUTOANTIBODY; CETIRIZINE; CLOZAPINE; HISTAMINE; HISTAMINE H4 RECEPTOR; RANITIDINE; THIOPERAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; DEGRANULATION; DISEASE SEVERITY; IMMUNE SYSTEM; MAST CELL; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BLOCKING; RHEUMATOID ARTHRITIS; SERUM;

AUTOIMMUNE DISEASE; HISTAMINE RECEPTOR ANTAGONIST; K/B×N MODEL;

ANIMALS; ARTHRITIS, RHEUMATOID; AUTOANTIBODIES; AUTOIMMUNE DISEASES; CLOZAPINE; DISEASE MODELS, ANIMAL; GLUCOSE-6-PHOSPHATE ISOMERASE; HISTAMINE ANTAGONISTS; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, TRANSGENIC; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE;

EID: 84880268528     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxt008     Document Type: Article

References (32)

1. Nigrovic, P. A. and Lee, D. M. 2005. Mast cells in inflammatory arthritis. Arthritis Res. Ther. 7:1.
2. Kouskoff, V., Korganow, A. S., Duchatelle, V., Degott, C., Benoist, C. and Mathis, D. 1996. Organ-specific disease provoked by systemic autoimmunity. Cell 87:811.
3. Ditzel, H. J. 2004. The K/BxN mouse: a model of human inflammatory arthritis. Trends Mol. Med. 10:40.
4. Kollias, G., Papadaki, P., Apparailly, F. et al. 2011. Animal models for arthritis: innovative tools for prevention and treatment. Ann. Rheum. Dis. 70:1357.
5. Alberts, B. 2004. Essential Cell Biology. 2nd edn Garland Science Pub., New York.
6. Kassahn, D., Kolb, C., Solomon, S., Bochtler, P. and Illges, H. 2002. Few human autoimmune sera detect GPI. Nat. Immunol. 3:411.
7. Matsumoto, I., Lee, D. M., Goldbach-Mansky, R. et al. 2003. Low prevalence of antibodies to glucose-6-phosphate isomerase in patients with rheumatoid arthritis and a spectrum of other chronic autoimmune disorders. Arthritis Rheum. 48:944.
8. Helder, A. E., Feltkamp-Vroom, T. M. and Nienhuis, R. L. 1973. Electron and light microscopical observations and serological findings in rheumatoid arthritis. Ann. Rheum. Dis. 32:515.
9. Lee, D. M., Friend, D. S., Gurish, M. F., Benoist, C., Mathis, D. and Brenner, M. B. 2002. Mast cells: a cellular link between autoantibodies and inflammatory arthritis. Science 297:1689.
10. Kneilling, M., Hültner, L., Pichler, B. J. et al. 2007. Targeted mast cell silencing protects against joint destruction and angiogenesis in experimental arthritis in mice. Arthritis Rheum. 56:1806.
11. Rajasekaran, N., Solomon, S., Watanabe, T. et al. 2009. Histidine decarboxylase but not histamine receptor 1 or 2 deficiency protects from K/BxN serum-induced arthritis. Int. Immunol. 21:1263.
12. Lovenberg, T. W., Roland, B. L., Wilson, S. J. et al. 1999. Cloning and functional expression of the human histamine H3 receptor. Mol. Pharmacol. 55:1101.
13. Ash, A. S. and Schild, H. O. 1966. Receptors mediating some actions of histamine. Br. J. Pharmacol. Chemother. 27:427.
14. Oda, T., Morikawa, N., Saito, Y., Masuho, Y. and Matsumoto, S. 2000. Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes. J. Biol. Chem. 275:367816.
15. Jutel, M., Watanabe, T., Akdis, M., Blaser, K. and Akdis, C. A. 2002. Immune regulation by histamine. Curr. Opin. Immunol. 14:735.
16. Leurs, R., Church, M. K. and Taglialatela, M. 2002. H1-antihistamines: inverse agonism, anti-inflammatory actions and cardiac effects. Clin. Exp. Allergy 32:489.
17. Yanai, K., Son, L. Z., Endou, M., Sakurai, E. and Watanabe, T. 1998. Targeting disruption of histamine H1 receptors in mice: behavioral and neurochemical characterization. Life Sci. 62:1607.
18. Del Valle, J. and Gantz, I. 1997. Novel insights into histamine H2 receptor biology. Am. J. Physiol. 273:G987.
19. Jutel, M., Akdis, M. and Akdis, C. A. 2009. Histamine, histamine receptors and their role in immune pathology. Clin. Exp. Allergy 39:1786.
20. Drutel, G., Peitsaro, N., Karlstedt, K. et al. 2001. Identification of rat H3 receptor isoforms with different brain expression and signaling properties. Mol. Pharmacol. 59:1.
21. Nakamura, T., Itadani, H., Hidaka, Y., Ohta, M. and Tanaka, K. 2000. Molecular cloning and characterization of a new human histamine receptor, HH4R. Biochem. Biophys. Res. Commun. 279:615.
22. de Esch, I. J., Thurmond, R. L., Jongejan, A. and Leurs, R. 2005. The histamine H4 receptor as a new therapeutic target for inflammation. Trends Pharmacol. Sci. 26:462.
23. Hofstra, C. L., Desai, P. J., Thurmond, R. L. and Fung-Leung, W. P. 2003. Histamine H4 receptor mediates chemotaxis and calcium mobilization of mast cells. J. Pharmacol. Exp. Ther. 305:1212.
24. Zampeli, E. and Tiligada, E. 2009. The role of histamine H4 receptor in immune and inflammatory disorders. Br. J. Pharmacol. 157:24.
25. Thurmond, R. L., Desai, P. J., Dunford, P. J. et al. 2004. A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties. J. Pharmacol. Exp. Ther. 309:404.
26. Desai, P. and Thurmond, R. L. 2011. Histamine H4 receptor activation enhances LPS-induced IL-6 production in mast cells via ERK and PI3K activation. Eur. J. Immunol. 41:1764.
27. Atkin, K., Kendall, F., Gould, D., Freeman, H., Liberman, J. and O'Sullivan, D. 1996. Neutropenia and agranulocytosis in patients receiving clozapine in the UK and Ireland. Br. J. Psychiatry 169:483.
28. Iverson, S., Kautiainen, A., Ip, J. and Uetrecht, J. P. 2010. Effect of clozapine on neutrophil kinetics in rabbits. Chem. Res. Toxicol. 23:1184.
29. Ip, J., Wilson, J. X. and Uetrecht, J. P. 2008. Testing the hypothesis that vitamin C deficiency is a risk factor for clozapine-induced agranulocytosis using guinea pigs and ODS rats. Chem. Res. Toxicol. 21:869.
30. Leurs, R., Chazot, P. L., Shenton, F. C., Lim, H. D. and de Esch, I. J. 2009. Molecular and biochemical pharmacology of the histamine H4 receptor. Br. J. Pharmacol. 157:14.
31. Ikawa, Y., Suzuki, M., Shiono, S. et al. 2005. Histamine H4 receptor expression in human synovial cells obtained from patients suffering from rheumatoid arthritis. Biol. Pharm. Bull. 28:2016.
32. Ohki, E., Suzuki, M., Aoe, T., Ikawa, Y., Negishi, E. and Ueno, K. 2007. Expression of histamine H4 receptor in synovial cells from rheumatoid arthritic patients. Biol. Pharm. Bull. 30:2217.