-
1
-
-
2342463654
-
Prospects for an AIDS vaccine
-
Desrosiers R. 2004. Prospects for an AIDS vaccine. Nat Med 10:221-223.
-
(2004)
Nat Med
, vol.10
, pp. 221-223
-
-
Desrosiers, R.1
-
2
-
-
48249134364
-
HIV vaccine research: the way forward
-
Fauci AS, Johnston MI, Dieffenbach CW, Burton DR, Hammer SM, Hoxie JA, Martin M, Overbaugh J, Watkins DI, Mahmoud A, Greene WC. 2008. HIV vaccine research: the way forward. Science 321:530-532.
-
(2008)
Science
, vol.321
, pp. 530-532
-
-
Fauci, A.S.1
Johnston, M.I.2
Dieffenbach, C.W.3
Burton, D.R.4
Hammer, S.M.5
Hoxie, J.A.6
Martin, M.7
Overbaugh, J.8
Watkins, D.I.9
Mahmoud, A.10
Greene, W.C.11
-
3
-
-
50949114906
-
The use of nonhuman primate models in HIV vaccine development
-
Morgan C, Marthas M, Miller C, Duerr A, Cheng-Mayer C, Desrosiers R, Flores J, Haigwood N, Hu SL, Johnson RP, Lifson J, Montefiori D, Moore J, Robert-Guroff M, Robinson H, Self S, Corey L. 2008. The use of nonhuman primate models in HIV vaccine development. PLoS Med 5: e173. doi:10.1371/journal.pmed.0050173.
-
(2008)
PLoS Med
, vol.5
-
-
Morgan, C.1
Marthas, M.2
Miller, C.3
Duerr, A.4
Cheng-Mayer, C.5
Desrosiers, R.6
Flores, J.7
Haigwood, N.8
Hu, S.L.9
Johnson, R.P.10
Lifson, J.11
Montefiori, D.12
Moore, J.13
Robert-Guroff, M.14
Robinson, H.15
Self, S.16
Corey, L.17
-
4
-
-
44049108744
-
Toward an AIDS vaccine
-
Walker B, Burton D. 2008. Toward an AIDS vaccine. Science 320:760-764.
-
(2008)
Science
, vol.320
, pp. 760-764
-
-
Walker, B.1
Burton, D.2
-
5
-
-
54049091269
-
Basic HIV Vaccine development
-
Watkins DI. 2008. Basic HIV Vaccine development. Top HIV Med 16:7-8.
-
(2008)
Top HIV Med
, vol.16
, pp. 7-8
-
-
Watkins, D.I.1
-
6
-
-
0027985431
-
Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody
-
Burton DR, Pyati J, Koduri R, Sharp SJ, Thornton GB, Parren PW, Sawyer LS, Hendry RM, Dunlop N, Nara PL, et al. 1994. Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody. Science 266:1024-1027.
-
(1994)
Science
, vol.266
, pp. 1024-1027
-
-
Burton, D.R.1
Pyati, J.2
Koduri, R.3
Sharp, S.J.4
Thornton, G.B.5
Parren, P.W.6
Sawyer, L.S.7
Hendry, R.M.8
Dunlop, N.9
Nara, P.L.10
-
7
-
-
0027378573
-
A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1
-
Muster T, Steindl F, Purtscher M, Trkola A, Klima A, Himmler G, Ruker F, Katinger H. 1993. A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1. J Virol 67:6642-6647.
-
(1993)
J Virol
, vol.67
, pp. 6642-6647
-
-
Muster, T.1
Steindl, F.2
Purtscher, M.3
Trkola, A.4
Klima, A.5
Himmler, G.6
Ruker, F.7
Katinger, H.8
-
8
-
-
9044241681
-
Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1
-
Trkola A, PurtscherM, Muster T, Ballaun C, Buchacher A, Sullivan N, Srinivasan K, Sodroski J, Moore JP, Katinger H. 1996. Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1. J Virol 70:1100-1108.
-
(1996)
J Virol
, vol.70
, pp. 1100-1108
-
-
Trkola, A.1
Purtscher, M.2
Muster, T.3
Ballaun, C.4
Buchacher, A.5
Sullivan, N.6
Srinivasan, K.7
Sodroski, J.8
Moore, J.P.9
Katinger, H.10
-
9
-
-
0034759882
-
Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41
-
Zwick MB, Labrijn AF, Wang M, Spenlehauer C, Saphire EO, Binley JM, Moore JP, Stiegler G, Katinger H, Burton DR, Parren PW. 2001. Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41. J Virol 75:10892-10905.
-
(2001)
J Virol
, vol.75
, pp. 10892-10905
-
-
Zwick, M.B.1
Labrijn, A.F.2
Wang, M.3
Spenlehauer, C.4
Saphire, E.O.5
Binley, J.M.6
Moore, J.P.7
Stiegler, G.8
Katinger, H.9
Burton, D.R.10
Parren, P.W.11
-
10
-
-
84863774072
-
Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses
-
Burton DR, Poignard P, Stanfield RL, Wilson IA. 2012. Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses. Science 337:183-186.
-
(2012)
Science
, vol.337
, pp. 183-186
-
-
Burton, D.R.1
Poignard, P.2
Stanfield, R.L.3
Wilson, I.A.4
-
11
-
-
80053132436
-
Broad neutralization coverage of HIV by multiple highly potent antibodies
-
Walker LM, Huber M, Doores KJ, Falkowska E, Pejchal R, Julien JP, Wang SK, Ramos A, Chan-Hui PY, Moyle M, Mitcham JL, Hammond PW, Olsen OA, Phung P, Fling S, Wong CH, Phogat S, Wrin T, Simek MD, Koff WC, Wilson IA, Burton DR, Poignard P. 2011. Broad neutralization coverage of HIV by multiple highly potent antibodies. Nature 477:466-470.
-
(2011)
Nature
, vol.477
, pp. 466-470
-
-
Walker, L.M.1
Huber, M.2
Doores, K.J.3
Falkowska, E.4
Pejchal, R.5
Julien, J.P.6
Wang, S.K.7
Ramos, A.8
Chan-Hui, P.Y.9
Moyle, M.10
Mitcham, J.L.11
Hammond, P.W.12
Olsen, O.A.13
Phung, P.14
Fling, S.15
Wong, C.H.16
Phogat, S.17
Wrin, T.18
Simek, M.D.19
Koff, W.C.20
Wilson, I.A.21
Burton, D.R.22
Poignard, P.23
more..
-
12
-
-
70349887757
-
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target
-
Walker LM, Phogat SK, Chan-Hui PY, Wagner D, Phung P, Goss JL, Wrin T, Simek MD, Fling S, Mitcham JL, Lehrman JK, Priddy FH, Olsen OA, Frey SM, Hammond PW, Kaminsky S, Zamb T, Moyle M, Koff WC, Poignard P, Burton DR. 2009. Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science 326:285-289.
-
(2009)
Science
, vol.326
, pp. 285-289
-
-
Walker, L.M.1
Phogat, S.K.2
Chan-Hui, P.Y.3
Wagner, D.4
Phung, P.5
Goss, J.L.6
Wrin, T.7
Simek, M.D.8
Fling, S.9
Mitcham, J.L.10
Lehrman, J.K.11
Priddy, F.H.12
Olsen, O.A.13
Frey, S.M.14
Hammond, P.W.15
Kaminsky, S.16
Zamb, T.17
Moyle, M.18
Koff, W.C.19
Poignard, P.20
Burton, D.R.21
more..
-
13
-
-
77954920017
-
Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1
-
Wu X, Yang ZY, Li Y, Hogerkorp CM, Schief WR, Seaman MS, Zhou T, Schmidt SD, Wu L, Xu L, Longo NS, McKee K, O'Dell S, Louder MK, Wycuff DL, Feng Y, Nason M, Doria-Rose N, Connors M, Kwong PD, Roederer M, Wyatt RT, Nabel GJ, Mascola JR. 2010. Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1. Science 329:856-861.
-
(2010)
Science
, vol.329
, pp. 856-861
-
-
Wu, X.1
Yang, Z.Y.2
Li, Y.3
Hogerkorp, C.M.4
Schief, W.R.5
Seaman, M.S.6
Zhou, T.7
Schmidt, S.D.8
Wu, L.9
Xu, L.10
Longo, N.S.11
McKee, K.12
O'Dell, S.13
Louder, M.K.14
Wycuff, D.L.15
Feng, Y.16
Nason, M.17
Doria-Rose, N.18
Connors, M.19
Kwong, P.D.20
Roederer, M.21
Wyatt, R.T.22
Nabel, G.J.23
Mascola, J.R.24
more..
-
14
-
-
67650453747
-
Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm
-
Simek MD, Rida W, Priddy FH, Pung P, Carrow E, Laufer DS, Lehrman JK, Boaz M, Tarragona-Fiol T, Miiro G, Birungi J, Pozniak A, McPhee DA, Manigart O, Karita E, Inwoley A, Jaoko W, Dehovitz J, Bekker LG, Pitisuttithum P, Paris R, Walker LM, Poignard P, Wrin T, Fast PE, Burton DR, Koff WC. 2009. Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm. J Virol 83:7337-7348.
-
(2009)
J Virol
, vol.83
, pp. 7337-7348
-
-
Simek, M.D.1
Rida, W.2
Priddy, F.H.3
Pung, P.4
Carrow, E.5
Laufer, D.S.6
Lehrman, J.K.7
Boaz, M.8
Tarragona-Fiol, T.9
Miiro, G.10
Birungi, J.11
Pozniak, A.12
McPhee, D.A.13
Manigart, O.14
Karita, E.15
Inwoley, A.16
Jaoko, W.17
Dehovitz, J.18
Bekker, L.G.19
Pitisuttithum, P.20
Paris, R.21
Walker, L.M.22
Poignard, P.23
Wrin, T.24
Fast, P.E.25
Burton, D.R.26
Koff, W.C.27
more..
-
15
-
-
0033952103
-
Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection
-
Baba TW, Liska V, Hofmann-Lehmann R, Vlasak J, Xu W, Ayehunie S, Cavacini LA, Posner MR, Katinger H, Stiegler G, Bernacky BJ, Rizvi TA, Schmidt R, Hill LR, Keeling ME, Lu Y, Wright JE, Chou TC, Ruprecht RM. 2000. Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection. Nat Med 6:200-206.
-
(2000)
Nat Med
, vol.6
, pp. 200-206
-
-
Baba, T.W.1
Liska, V.2
Hofmann-Lehmann, R.3
Vlasak, J.4
Xu, W.5
Ayehunie, S.6
Cavacini, L.A.7
Posner, M.R.8
Katinger, H.9
Stiegler, G.10
Bernacky, B.J.11
Rizvi, T.A.12
Schmidt, R.13
Hill, L.R.14
Keeling, M.E.15
Lu, Y.16
Wright, J.E.17
Chou, T.C.18
Ruprecht, R.M.19
-
16
-
-
0033951746
-
Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies
-
Mascola JR, Stiegler G, VanCott TC, Katinger H, Carpenter CB, Hanson CE, Beary H, Hayes D, Frankel SS, Birx DL, Lewis MG. 2000. Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies. Nat Med 6:207-210.
-
(2000)
Nat Med
, vol.6
, pp. 207-210
-
-
Mascola, J.R.1
Stiegler, G.2
VanCott, T.C.3
Katinger, H.4
Carpenter, C.B.5
Hanson, C.E.6
Beary, H.7
Hayes, D.8
Frankel, S.S.9
Birx, D.L.10
Lewis, M.G.11
-
17
-
-
0034864776
-
Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro
-
Parren PW, Marx PA, Hessell AJ, Luckay A, Harouse J, Cheng-Mayer C, Moore J., Burton DR. 2001. Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro. J Virol 75: 8340-8347.
-
(2001)
J Virol
, vol.75
, pp. 8340-8347
-
-
Parren, P.W.1
Marx, P.A.2
Hessell, A.J.3
Luckay, A.4
Harouse, J.5
Cheng-Mayer, C.6
Moore, J.7
Burton, D.R.8
-
18
-
-
68349160853
-
Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques
-
Hessell AJ, Poignard P, Hunter M, Hangartner L, Tehrani DM, Bleeker WK, Parren PW, Marx PA, Burton DR. 2009. Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques. Nat Med 15:951-954.
-
(2009)
Nat Med
, vol.15
, pp. 951-954
-
-
Hessell, A.J.1
Poignard, P.2
Hunter, M.3
Hangartner, L.4
Tehrani, D.M.5
Bleeker, W.K.6
Parren, P.W.7
Marx, P.A.8
Burton, D.R.9
-
19
-
-
67249131966
-
Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers
-
Hessell AJ, Rakasz EG, Poignard P, Hangartner L, Landucci G, Forthal DN, Koff WC, Watkins DI, Burton DR. 2009. Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers. PLoS Pathog 5:e1000433. doi:10.1371/journal.ppat.1000433.
-
(2009)
PLoS Pathog
, vol.5
-
-
Hessell, A.J.1
Rakasz, E.G.2
Poignard, P.3
Hangartner, L.4
Landucci, G.5
Forthal, D.N.6
Koff, W.C.7
Watkins, D.I.8
Burton, D.R.9
-
20
-
-
76449108010
-
Neutralizing antibody titers conferring protection to macaques from a simian/human immunodeficiency virus challenge using the TZM-bl assay
-
Willey R, Nason MC, Nishimura Y, Follmann DA, Martin MA. 2010. Neutralizing antibody titers conferring protection to macaques from a simian/human immunodeficiency virus challenge using the TZM-bl assay. AIDS Res Hum Retroviruses 26:89-98.
-
(2010)
AIDS Res Hum Retroviruses
, vol.26
, pp. 89-98
-
-
Willey, R.1
Nason, M.C.2
Nishimura, Y.3
Follmann, D.A.4
Martin, M.A.5
-
22
-
-
68349150945
-
Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys
-
Johnson PR, Schnepp BC, Zhang J, Connell MJ, Greene SM, Yuste E, Desrosiers RC, Clark KR. 2009. Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys. Nat Med 15:901-906.
-
(2009)
Nat Med
, vol.15
, pp. 901-906
-
-
Johnson, P.R.1
Schnepp, B.C.2
Zhang, J.3
Connell, M.J.4
Greene, S.M.5
Yuste, E.6
Desrosiers, R.C.7
Clark, K.R.8
-
23
-
-
56649105122
-
Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial
-
Buchbinder SP, Mehrotra DV, Duerr A, Fitzgerald DW, Mogg R, Li D, Gilbert PB, Lama JR, Marmor M, Del Rio C, McElrath MJ, Casimiro DR, Gottesdiener KM, Chodakewitz JA, Corey L, Robertson MN. 2008. Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial. Lancet 372:1881-1893.
-
(2008)
Lancet
, vol.372
, pp. 1881-1893
-
-
Buchbinder, S.P.1
Mehrotra, D.V.2
Duerr, A.3
Fitzgerald, D.W.4
Mogg, R.5
Li, D.6
Gilbert, P.B.7
Lama, J.R.8
Marmor, M.9
Del Rio, C.10
McElrath, M.J.11
Casimiro, D.R.12
Gottesdiener, K.M.13
Chodakewitz, J.A.14
Corey, L.15
Robertson, M.N.16
-
24
-
-
13944254982
-
Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection
-
Flynn NM, Forthal DN, Harro CD, Judson FN, Mayer KH, Para MF. 2005. Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection. J Infect Dis 191:654-665.
-
(2005)
J Infect Dis
, vol.191
, pp. 654-665
-
-
Flynn, N.M.1
Forthal, D.N.2
Harro, C.D.3
Judson, F.N.4
Mayer, K.H.5
Para, M.F.6
-
25
-
-
56649114351
-
HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a casecohort analysis
-
McElrath MJ, De Rosa SC, Moodie Z, Dubey S, Kierstead L, Janes H, Defawe OD, Carter DK, Hural J, Akondy R, Buchbinder SP, Robertson MN, Mehrotra DV, Self SG, Corey L, Shiver JW, Casimiro DR. 2008. HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a casecohort analysis. Lancet 372:1894-1905.
-
(2008)
Lancet
, vol.372
, pp. 1894-1905
-
-
McElrath, M.J.1
De Rosa, S.C.2
Moodie, Z.3
Dubey, S.4
Kierstead, L.5
Janes, H.6
Defawe, O.D.7
Carter, D.K.8
Hural, J.9
Akondy, R.10
Buchbinder, S.P.11
Robertson, M.N.12
Mehrotra, D.V.13
Self, S.G.14
Corey, L.15
Shiver, J.W.16
Casimiro, D.R.17
-
26
-
-
33845433434
-
Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand
-
Pitisuttithum P, Gilbert P, Gurwith M, Heyward W, Martin M, van Griensven F, Hu D, Tappero JW, Choopanya K. 2006. Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand. J Infect Dis 194:1661-1671.
-
(2006)
J Infect Dis
, vol.194
, pp. 1661-1671
-
-
Pitisuttithum, P.1
Gilbert, P.2
Gurwith, M.3
Heyward, W.4
Martin, M.5
van Griensven, F.6
Hu, D.7
Tappero, J.W.8
Choopanya, K.9
-
27
-
-
73349094086
-
Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand
-
Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, Kaewkungwal J, Chiu J, Paris R, Premsri N, Namwat C, de Souza M, Adams E, Benenson M, Gurunathan S, Tartaglia J, McNeil JG, Francis DP, Stablein D, Birx DL, Chunsuttiwat S, Khamboonruang C, Thongcharoen P, Robb ML, Michael NL, Kunasol P, Kim JH. 2009. Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N Engl J Med 361:2209-2220.
-
(2009)
N Engl J Med
, vol.361
, pp. 2209-2220
-
-
Rerks-Ngarm, S.1
Pitisuttithum, P.2
Nitayaphan, S.3
Kaewkungwal, J.4
Chiu, J.5
Paris, R.6
Premsri, N.7
Namwat, C.8
de Souza, M.9
Adams, E.10
Benenson, M.11
Gurunathan, S.12
Tartaglia, J.13
McNeil, J.G.14
Francis, D.P.15
Stablein, D.16
Birx, D.L.17
Chunsuttiwat, S.18
Khamboonruang, C.19
Thongcharoen, P.20
Robb, M.L.21
Michael, N.L.22
Kunasol, P.23
Kim, J.H.24
more..
-
28
-
-
84859393693
-
Immune-correlates analysis of an HIV-1 vaccine efficacy trial
-
Haynes BF, Gilbert PB, McElrath MJ, Zolla-Pazner S, Tomaras GD, Alam SM, Evans DT, Montefiori DC, Karnasuta C, Sutthent R, Liao HX, DeVico AL, Lewis GK, Williams C, Pinter A, Fong Y, Janes H, DeCamp A, Huang Y, Rao M, Billings E, Karasavvas N, Robb ML, Ngauy V, de Souza MS, Paris R, Ferrari G, Bailer RT, Soderberg KA, Andrews C, Berman PW, Frahm N, De Rosa SC, Alpert MD, Yates NL, Shen X, Koup RA, Pitisuttithum P, Kaewkungwal J, Nitayaphan S, Rerks-Ngarm S, Michael NL, Kim JH. 2012. Immune-correlates analysis of an HIV-1 vaccine efficacy trial. N Engl J Med 366:1275-1286.
-
(2012)
N Engl J Med
, vol.366
, pp. 1275-1286
-
-
Haynes, B.F.1
Gilbert, P.B.2
McElrath, M.J.3
Zolla-Pazner, S.4
Tomaras, G.D.5
Alam, S.M.6
Evans, D.T.7
Montefiori, D.C.8
Karnasuta, C.9
Sutthent, R.10
Liao, H.X.11
DeVico, A.L.12
Lewis, G.K.13
Williams, C.14
Pinter, A.15
Fong, Y.16
Janes, H.17
DeCamp, A.18
Huang, Y.19
Rao, M.20
Billings, E.21
Karasavvas, N.22
Robb, M.L.23
Ngauy, V.24
de Souza, M.S.25
Paris, R.26
Ferrari, G.27
Bailer, R.T.28
Soderberg, K.A.29
Andrews, C.30
Berman, P.W.31
Frahm, N.32
De Rosa, S.C.33
Alpert, M.D.34
Yates, N.L.35
Shen, X.36
Koup, R.A.37
Pitisuttithum, P.38
Kaewkungwal, J.39
Nitayaphan, S.40
Rerks-Ngarm, S.41
Michael, N.L.42
Kim, J.H.43
more..
-
29
-
-
84887865083
-
Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine
-
Hammer SM, Sobieszczyk ME, Janes H, Karuna ST, Mulligan MJ, Grove D, Koblin BA, Buchbinder SP, Keefer MC, Tomaras GD, Frahm N, Hural J, Anude C, Graham BS, Enama ME, Adams E, De Jesus E, Novak RM, Frank I, Bentley C, Ramirez S, Fu R, Koup RA, Mascola JR, Nabel GJ, Montefiori DC, Kublin J, McElrath MJ, Corey L, Gilbert PB. 2013. Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine. N Engl J Med 369:2083-2092.
-
(2013)
N Engl J Med
, vol.369
, pp. 2083-2092
-
-
Hammer, S.M.1
Sobieszczyk, M.E.2
Janes, H.3
Karuna, S.T.4
Mulligan, M.J.5
Grove, D.6
Koblin, B.A.7
Buchbinder, S.P.8
Keefer, M.C.9
Tomaras, G.D.10
Frahm, N.11
Hural, J.12
Anude, C.13
Graham, B.S.14
Enama, M.E.15
Adams, E.16
De Jesus, E.17
Novak, R.M.18
Frank, I.19
Bentley, C.20
Ramirez, S.21
Fu, R.22
Koup, R.A.23
Mascola, J.R.24
Nabel, G.J.25
Montefiori, D.C.26
Kublin, J.27
McElrath, M.J.28
Corey, L.29
Gilbert, P.B.30
more..
-
30
-
-
84866493348
-
Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
-
Huang J, Ofek G, Laub L, Louder MK, Doria-Rose NA, Longo NS, Imamichi H, Bailer RT, Chakrabarti B, Sharma SK, Alam SM, Wang T, Yang Y, Zhang B, Migueles SA, Wyatt R, Haynes BF, Kwong PD, Mascola JR, Connors M. 2012. Broad and potent neutralization of HIV-1 by a gp41-specific human antibody. Nature 491:406-412.
-
(2012)
Nature
, vol.491
, pp. 406-412
-
-
Huang, J.1
Ofek, G.2
Laub, L.3
Louder, M.K.4
Doria-Rose, N.A.5
Longo, N.S.6
Imamichi, H.7
Bailer, R.T.8
Chakrabarti, B.9
Sharma, S.K.10
Alam, S.M.11
Wang, T.12
Yang, Y.13
Zhang, B.14
Migueles, S.A.15
Wyatt, R.16
Haynes, B.F.17
Kwong, P.D.18
Mascola, J.R.19
Connors, M.20
more..
-
31
-
-
80052925616
-
Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding
-
Scheid JF, Mouquet H, Ueberheide B, Diskin R, Klein F, Oliveira TY, Pietzsch J, Fenyo D, Abadir A, Velinzon K, Hurley A, Myung S, Boulad F, Poignard P, Burton DR, Pereyra F, Ho DD, Walker BD, Seaman MS, Bjorkman PJ, Chait BT, Nussenzweig MC. 2011. Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding. Science 333:1633-1637.
-
(2011)
Science
, vol.333
, pp. 1633-1637
-
-
Scheid, J.F.1
Mouquet, H.2
Ueberheide, B.3
Diskin, R.4
Klein, F.5
Oliveira, T.Y.6
Pietzsch, J.7
Fenyo, D.8
Abadir, A.9
Velinzon, K.10
Hurley, A.11
Myung, S.12
Boulad, F.13
Poignard, P.14
Burton, D.R.15
Pereyra, F.16
Ho, D.D.17
Walker, B.D.18
Seaman, M.S.19
Bjorkman, P.J.20
Chait, B.T.21
Nussenzweig, M.C.22
more..
-
32
-
-
77954943648
-
Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01
-
Zhou T, Georgiev I, Wu X, Yang ZY, Dai K, Finzi A, Kwon YD, Scheid JF, Shi W, Xu L, Yang Y, Zhu J, Nussenzweig MC, Sodroski J, Shapiro L, Nabel GJ, Mascola JR, Kwong PD. 2010. Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01. Science 329:811-817.
-
(2010)
Science
, vol.329
, pp. 811-817
-
-
Zhou, T.1
Georgiev, I.2
Wu, X.3
Yang, Z.Y.4
Dai, K.5
Finzi, A.6
Kwon, Y.D.7
Scheid, J.F.8
Shi, W.9
Xu, L.10
Yang, Y.11
Zhu, J.12
Nussenzweig, M.C.13
Sodroski, J.14
Shapiro, L.15
Nabel, G.J.16
Mascola, J.R.17
Kwong, P.D.18
-
33
-
-
80052938385
-
Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors
-
Bonsignori M, Hwang KK, Chen X, Tsao CY, Morris L, Gray E, Marshall DJ, Crump JA, Kapiga SH, Sam NE, Sinangil F, Pancera M, Yongping Y, Zhang B, Zhu J, Kwong PD, O'Dell S, Mascola JR, Wu L, Nabel GJ, Phogat S, Seaman MS, Whitesides JF, Moody MA, Kelsoe G, Yang X, Sodroski J, M. Shaw G, Montefiori DC, Kepler TB, Tomaras GD, Alam SM, Liao HX, Haynes BF. 2011. Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors. J Virol 85:9998-10009.
-
(2011)
J Virol
, vol.85
, pp. 9998-10009
-
-
Bonsignori, M.1
Hwang, K.K.2
Chen, X.3
Tsao, C.Y.4
Morris, L.5
Gray, E.6
Marshall, D.J.7
Crump, J.A.8
Kapiga, S.H.9
Sam, N.E.10
Sinangil, F.11
Pancera, M.12
Yongping, Y.13
Zhang, B.14
Zhu, J.15
Kwong, P.D.16
O'Dell, S.17
Mascola, J.R.18
Wu, L.19
Nabel, G.J.20
Phogat, S.21
Seaman, M.S.22
Whitesides, J.F.23
Moody, M.A.24
Kelsoe, G.25
Yang, X.26
Sodroski, J.27
Shaw, M.G.28
Montefiori, D.C.29
Kepler, T.B.30
Tomaras, G.D.31
Alam, S.M.32
Liao, H.X.33
Haynes, B.F.34
more..
-
34
-
-
84861374644
-
PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4
-
Falkowska E, Ramos A, Feng Y, Zhou T, Moquin S, Walker LM, Wu X, Seaman MS, Wrin T, Kwong PD, Wyatt RT, Mascola JR, Poignard P, Burton DR. 2012. PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4. J Virol 86:4394-4403.
-
(2012)
J Virol
, vol.86
, pp. 4394-4403
-
-
Falkowska, E.1
Ramos, A.2
Feng, Y.3
Zhou, T.4
Moquin, S.5
Walker, L.M.6
Wu, X.7
Seaman, M.S.8
Wrin, T.9
Kwong, P.D.10
Wyatt, R.T.11
Mascola, J.R.12
Poignard, P.13
Burton, D.R.14
-
35
-
-
84883187027
-
Broadly neutralizing antibodies and the search for an HIV-1 vaccine: the end of the beginning
-
Kwong PD, Mascola JR, Nabel GJ. 2013. Broadly neutralizing antibodies and the search for an HIV-1 vaccine: the end of the beginning. Nat Rev Immunol 13:693-701.
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 693-701
-
-
Kwong, P.D.1
Mascola, J.R.2
Nabel, G.J.3
-
36
-
-
84882589754
-
Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies
-
Zhou T, Zhu J, Wu X, Moquin S, Zhang B, Acharya P, Georgiev IS, Altae-Tran HR, Chuang GY, Joyce MG, Do Kwon Y, Longo NS, Louder MK, Luongo T, McKee K, Schramm CA, Skinner J, Yang Y, Yang Z, Zhang Z, Zheng A, Bonsignori M, Haynes BF, Scheid JF, Nussenzweig MC, Simek M, Burton DR, Koff WC, Mullikin JC, Connors M, Shapiro L, Nabel GJ, Mascola JR, Kwong PD. 2013. Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies. Immunity 39:245-258.
-
(2013)
Immunity
, vol.39
, pp. 245-258
-
-
Zhou, T.1
Zhu, J.2
Wu, X.3
Moquin, S.4
Zhang, B.5
Acharya, P.6
Georgiev, I.S.7
Altae-Tran, H.R.8
Chuang, G.Y.9
Joyce, M.G.10
Do Kwon, Y.11
Longo, N.S.12
Louder, M.K.13
Luongo, T.14
McKee, K.15
Schramm, C.A.16
Skinner, J.17
Yang, Y.18
Yang, Z.19
Zhang, Z.20
Zheng, A.21
Bonsignori, M.22
Haynes, B.F.23
Scheid, J.F.24
Nussenzweig, M.C.25
Simek, M.26
Burton, D.R.27
Koff, W.C.28
Mullikin, J.C.29
Connors, M.30
Shapiro, L.31
Nabel, G.J.32
Mascola, J.R.33
Kwong, P.D.34
more..
-
37
-
-
84887315888
-
Recognition of synthetic glycopeptides by HIV-1 broadly neutralizing antibodies and their unmutated ancestors
-
Alam SM, Dennison SM, Aussedat B, Vohra Y, Park PK, Fernandez-Tejada A, Stewart S, Jaeger FH, Anasti K, Blinn JH, Kepler TB, Bonsignori M, Liao HX, Sodroski JG, Danishefsky SJ, Haynes BF. 2013. Recognition of synthetic glycopeptides by HIV-1 broadly neutralizing antibodies and their unmutated ancestors. Proc Natl Acad Sci USA 110:18214-18219.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 18214-18219
-
-
Alam, S.M.1
Dennison, S.M.2
Aussedat, B.3
Vohra, Y.4
Park, P.K.5
Fernandez-Tejada, A.6
Stewart, S.7
Jaeger, F.H.8
Anasti, K.9
Blinn, J.H.10
Kepler, T.B.11
Bonsignori, M.12
Liao, H.X.13
Sodroski, J.G.14
Danishefsky, S.J.15
Haynes, B.F.16
-
38
-
-
84877609579
-
Rational HIV immunogen design to target specific germline B cell receptors
-
Jardine J, Julien JP, Menis S, Ota T, Kalyuzhniy O, McGuire A, Sok D, Huang PS, MacPherson S, Jones M, Nieusma T, Mathison J, Baker D, Ward AB, Burton DR, Stamatatos L, Nemazee D, Wilson IA, Schief WR. 2013. Rational HIV immunogen design to target specific germline B cell receptors. Science 340:711-716.
-
(2013)
Science
, vol.340
, pp. 711-716
-
-
Jardine, J.1
Julien, J.P.2
Menis, S.3
Ota, T.4
Kalyuzhniy, O.5
McGuire, A.6
Sok, D.7
Huang, P.S.8
MacPherson, S.9
Jones, M.10
Nieusma, T.11
Mathison, J.12
Baker, D.13
Ward, A.B.14
Burton, D.R.15
Stamatatos, L.16
Nemazee, D.17
Wilson, I.A.18
Schief, W.R.19
-
39
-
-
84869232528
-
Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo
-
Moldt B, Rakasz EG, Schultz N, Chan-Hui PY, Swiderek K, Weisgrau KL, Piaskowski SM, Bergman Z, Watkins DI, Poignard P, Burton DR. 2012. Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo. Proc Natl Acad Sci USA 109:18921-18925.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 18921-18925
-
-
Moldt, B.1
Rakasz, E.G.2
Schultz, N.3
Chan-Hui, P.Y.4
Swiderek, K.5
Weisgrau, K.L.6
Piaskowski, S.M.7
Bergman, Z.8
Watkins, D.I.9
Poignard, P.10
Burton, D.R.11
-
40
-
-
77956642770
-
Reengineered AAV vectors: old dog, new tricks
-
Asokan A. 2010. Reengineered AAV vectors: old dog, new tricks. Discov Med 9:399-403.
-
(2010)
Discov Med
, vol.9
, pp. 399-403
-
-
Asokan, A.1
-
41
-
-
36749033228
-
The state of the art of adenoassociated virus-based vectors in gene therapy
-
Coura Rdos S, Nardi NB. 2007. The state of the art of adenoassociated virus-based vectors in gene therapy. Virol J 4:99. doi:10.1186/1743-422X-4-99.
-
(2007)
Virol J
, vol.4
, pp. 99
-
-
Coura Rdos, S.1
Nardi, N.B.2
-
42
-
-
54249126862
-
Gene therapy using adeno-associated virus vectors
-
Daya S, Berns KI. 2008. Gene therapy using adeno-associated virus vectors. Clin Microbiol Rev 21:583-593.
-
(2008)
Clin Microbiol Rev
, vol.21
, pp. 583-593
-
-
Daya, S.1
Berns, K.I.2
-
43
-
-
84861912888
-
Integration frequency and intermolecular recombination of rAAV vectors in non-human primate skeletal muscle and liver
-
Nowrouzi A, Penaud-Budloo M, Kaeppel C, Appelt U, Le Guiner C, Moullier P, von Kalle C, Snyder RO, Schmidt M. 2012. Integration frequency and intermolecular recombination of rAAV vectors in non-human primate skeletal muscle and liver. Mol Ther 20:1177-1186.
-
(2012)
Mol Ther
, vol.20
, pp. 1177-1186
-
-
Nowrouzi, A.1
Penaud-Budloo, M.2
Kaeppel, C.3
Appelt, U.4
Le Guiner, C.5
Moullier, P.6
von Kalle, C.7
Snyder, R.O.8
Schmidt, M.9
-
44
-
-
49149113894
-
Adeno-associated virus vector genomes persist as episomal chromatin in primate muscle
-
Penaud-Budloo M, Le Guiner C, Nowrouzi A, Toromanoff A, Cherel Y, Chenuaud P, Schmidt M, von Kalle C, Rolling F, Moullier P, Snyder RO. 2008. Adeno-associated virus vector genomes persist as episomal chromatin in primate muscle. J Virol 82:7875-7885.
-
(2008)
J Virol
, vol.82
, pp. 7875-7885
-
-
Penaud-Budloo, M.1
Le Guiner, C.2
Nowrouzi, A.3
Toromanoff, A.4
Cherel, Y.5
Chenuaud, P.6
Schmidt, M.7
von Kalle, C.8
Rolling, F.9
Moullier, P.10
Snyder, R.O.11
-
45
-
-
0037333815
-
Genetic fate of recombinant adeno-associated virus vector genomes in muscle
-
Schnepp BC, Clark KR, Klemanski DL, Pacak CA, Johnson PR. 2003. Genetic fate of recombinant adeno-associated virus vector genomes in muscle. J Virol 77:3495-3504.
-
(2003)
J Virol
, vol.77
, pp. 3495-3504
-
-
Schnepp, B.C.1
Clark, K.R.2
Klemanski, D.L.3
Pacak, C.A.4
Johnson, P.R.5
-
46
-
-
80053492356
-
Advancements in adeno-associated viral gene therapy approaches: exploring a new horizon
-
Aalbers CJ, Tak PP, Vervoordeldonk MJ. 2011. Advancements in adeno-associated viral gene therapy approaches: exploring a new horizon. F1000 Med Rep 3:17. doi:10.3410/M3-17.
-
(2011)
F1000 Med Rep
, vol.3
, pp. 17
-
-
Aalbers, C.J.1
Tak, P.P.2
Vervoordeldonk, M.J.3
-
47
-
-
0036340378
-
Generation of neutralizing activity against human immunodeficiency virus type 1 in serum by antibody gene transfer
-
Lewis AD, Chen R, Montefiori DC, Johnson PR, Clark KR. 2002. Generation of neutralizing activity against human immunodeficiency virus type 1 in serum by antibody gene transfer. J Virol 76:8769-8775.
-
(2002)
J Virol
, vol.76
, pp. 8769-8775
-
-
Lewis, A.D.1
Chen, R.2
Montefiori, D.C.3
Johnson, P.R.4
Clark, K.R.5
-
48
-
-
22744444388
-
Stable antibody expression at therapeutic levels using the 2A peptide
-
Fang JM, Qian JJ, Yi SY, Harding TC, Tu GH, VanRoey M, Jooss K. 2005. Stable antibody expression at therapeutic levels using the 2A peptide. Nat Biotechnol 23:584-590.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 584-590
-
-
Fang, J.M.1
Qian, J.J.2
Yi, S.Y.3
Harding, T.C.4
Tu, G.H.5
VanRoey, M.6
Jooss, K.7
-
49
-
-
0030932133
-
Immunoadhesins as research tools and therapeutic agents
-
Ashkenazi A, Chamow SM. 1997. Immunoadhesins as research tools and therapeutic agents. Curr Opin Immunol 9:195-200.
-
(1997)
Curr Opin Immunol
, vol.9
, pp. 195-200
-
-
Ashkenazi, A.1
Chamow, S.M.2
-
50
-
-
0024575860
-
Designing CD4 immunoadhesins for AIDS therapy
-
Capon DJ, Chamow SM, Mordenti J, Marsters SA, Gregory T, Mitsuya H, Byrn RA, Lucas C, Wurm FM, Groopman JE, Broder S, Smith DH. 1989. Designing CD4 immunoadhesins for AIDS therapy. Nature 337:525-531.
-
(1989)
Nature
, vol.337
, pp. 525-531
-
-
Capon, D.J.1
Chamow, S.M.2
Mordenti, J.3
Marsters, S.A.4
Gregory, T.5
Mitsuya, H.6
Byrn, R.A.7
Lucas, C.8
Wurm, F.M.9
Groopman, J.E.10
Broder, S.11
Smith, D.H.12
-
51
-
-
85042811690
-
Intranasal antibody gene transfer in mice and ferrets elicits broad protection against pandemic influenza
-
Limberis MP, Adam VS, Wong G, Gren J, Kobasa D, Ross TM, Kobinger GP, Tretiakova A, Wilson JM. 2013. Intranasal antibody gene transfer in mice and ferrets elicits broad protection against pandemic influenza. Sci Transl Med 5:187ra172. doi:10.1126/scitranslmed.3006299.
-
(2013)
Sci Transl Med
, vol.5
-
-
Limberis, M.P.1
Adam, V.S.2
Wong, G.3
Gren, J.4
Kobasa, D.5
Ross, T.M.6
Kobinger, G.P.7
Tretiakova, A.8
Wilson, J.M.9
-
52
-
-
79960141758
-
Safety and efficacy of etanercept beyond 10 years of therapy in North American patients with early and longstanding rheumatoid arthritis
-
Weinblatt ME, Bathon JM, Kremer JM, Fleischmann RM, Schiff MH, Martin RW, Baumgartner SW, Park GS, Mancini EL, Genovese MC. 2011. Safety and efficacy of etanercept beyond 10 years of therapy in North American patients with early and longstanding rheumatoid arthritis. Arthritis Care Res (Hoboken) 63:373-382.
-
(2011)
Arthritis Care Res (Hoboken)
, vol.63
, pp. 373-382
-
-
Weinblatt, M.E.1
Bathon, J.M.2
Kremer, J.M.3
Fleischmann, R.M.4
Schiff, M.H.5
Martin, R.W.6
Baumgartner, S.W.7
Park, G.S.8
Mancini, E.L.9
Genovese, M.C.10
-
53
-
-
0141458878
-
Assorted mutations in the envelope gene of simian immunodeficiency virus lead to loss of neutralization resistance against antibodies representing a broad spectrum of specificities
-
Johnson WE, Sanford H, Schwall L, Burton DR, Parren PW, Robinson JE, Desrosiers RC. 2003. Assorted mutations in the envelope gene of simian immunodeficiency virus lead to loss of neutralization resistance against antibodies representing a broad spectrum of specificities. J Virol 77:9993-10003.
-
(2003)
J Virol
, vol.77
, pp. 9993-10003
-
-
Johnson, W.E.1
Sanford, H.2
Schwall, L.3
Burton, D.R.4
Parren, P.W.5
Robinson, J.E.6
Desrosiers, R.C.7
-
54
-
-
0027257744
-
Synergistic inhibition of HIV-1 envelope-mediated cell fusion by CD4-based molecules in combination with antibodies to gp120 or gp41
-
Allaway GP, Ryder AM, Beaudry GA, Maddon PJ. 1993. Synergistic inhibition of HIV-1 envelope-mediated cell fusion by CD4-based molecules in combination with antibodies to gp120 or gp41. AIDS Res Hum Retroviruses 9:581-587.
-
(1993)
AIDS Res Hum Retroviruses
, vol.9
, pp. 581-587
-
-
Allaway, G.P.1
Ryder, A.M.2
Beaudry, G.A.3
Maddon, P.J.4
-
55
-
-
84855466746
-
Antibody-based protection against HIV infection by vectored immunoprophylaxis
-
Balazs AB, Chen J, Hong CM, Rao DS, Yang L, Baltimore D. 2012. Antibody-based protection against HIV infection by vectored immunoprophylaxis. Nature 481:81-84.
-
(2012)
Nature
, vol.481
, pp. 81-84
-
-
Balazs, A.B.1
Chen, J.2
Hong, C.M.3
Rao, D.S.4
Yang, L.5
Baltimore, D.6
-
56
-
-
84885338257
-
HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice
-
Horwitz JA, Halper-Stromberg A, Mouquet H, Gitlin AD, Tretiakova A, Eisenreich TR, Malbec M, Gravemann S, Billerbeck E, Dorner M, Buning H, Schwartz O, Knops E, Kaiser R, Seaman MS, Wilson JM, Rice CM, Ploss A, Bjorkman PJ, Klein F, Nussenzweig MC. 2013. HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice. Proc Natl Acad Sci USA 110:16538-16543.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 16538-16543
-
-
Horwitz, J.A.1
Halper-Stromberg, A.2
Mouquet, H.3
Gitlin, A.D.4
Tretiakova, A.5
Eisenreich, T.R.6
Malbec, M.7
Gravemann, S.8
Billerbeck, E.9
Dorner, M.10
Buning, H.11
Schwartz, O.12
Knops, E.13
Kaiser, R.14
Seaman, M.S.15
Wilson, J.M.16
Rice, C.M.17
Ploss, A.18
Bjorkman, P.J.19
Klein, F.20
Nussenzweig, M.C.21
more..
-
57
-
-
84869831194
-
Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies
-
Mouquet H, Scharf L, Euler Z, Liu Y, Eden C, Scheid JF, Halper-Stromberg A, Gnanapragasam PN, Spencer DI, Seaman MS, Schuitemaker H, Feizi T, Nussenzweig MC, Bjorkman PJ. 2012. Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies. Proc Natl Acad Sci USA 109:E3268-E3277.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. E3268-E3277
-
-
Mouquet, H.1
Scharf, L.2
Euler, Z.3
Liu, Y.4
Eden, C.5
Scheid, J.F.6
Halper-Stromberg, A.7
Gnanapragasam, P.N.8
Spencer, D.I.9
Seaman, M.S.10
Schuitemaker, H.11
Feizi, T.12
Nussenzweig, M.C.13
Bjorkman, P.J.14
-
58
-
-
84870562234
-
HIV therapy by a combination of broadly neutralizing antibodies in humanized mice
-
Klein F, Halper-Stromberg A, Horwitz JA, Gruell H, Scheid JF, Bournazos S, Mouquet H, Spatz LA, Diskin R, Abadir A, Zang T, Dorner M, Billerbeck E, Labitt RN, Gaebler C, Marcovecchio PM, Incesu RB, Eisenreich TR, Bieniasz PD, Seaman MS, Bjorkman PJ, Ravetch JV, Ploss A, Nussenzweig MC. 2012. HIV therapy by a combination of broadly neutralizing antibodies in humanized mice. Nature 492:118-122.
-
(2012)
Nature
, vol.492
, pp. 118-122
-
-
Klein, F.1
Halper-Stromberg, A.2
Horwitz, J.A.3
Gruell, H.4
Scheid, J.F.5
Bournazos, S.6
Mouquet, H.7
Spatz, L.A.8
Diskin, R.9
Abadir, A.10
Zang, T.11
Dorner, M.12
Billerbeck, E.13
Labitt, R.N.14
Gaebler, C.15
Marcovecchio, P.M.16
Incesu, R.B.17
Eisenreich, T.R.18
Bieniasz, P.D.19
Seaman, M.S.20
Bjorkman, P.J.21
Ravetch, J.V.22
Ploss, A.23
Nussenzweig, M.C.24
more..
-
59
-
-
47749126913
-
Genetic delivery of an anti-RSV antibody to protect against pulmonary infection with RSV
-
Skaricic D, Traube C, De B, Joh J, Boyer J, Crystal RG, Worgall S. 2008. Genetic delivery of an anti-RSV antibody to protect against pulmonary infection with RSV. Virology 378:79-85.
-
(2008)
Virology
, vol.378
, pp. 79-85
-
-
Skaricic, D.1
Traube, C.2
De, B.3
Joh, J.4
Boyer, J.5
Crystal, R.G.6
Worgall, S.7
-
60
-
-
80051670323
-
A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins
-
Corti D, Voss J, Gamblin SJ, Codoni G, Macagno A, Jarrossay D, Vachieri SG, Pinna D, Minola A, Vanzetta F, Silacci C, Fernandez-Rodriguez BM, Agatic G, Bianchi S, Giacchetto-Sasselli I, Calder L, Sallusto F, Collins P, Haire LF, Temperton N, Langedijk JP, Skehel JJ, Lanzavecchia A. 2011. A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins. Science 333:850-856.
-
(2011)
Science
, vol.333
, pp. 850-856
-
-
Corti, D.1
Voss, J.2
Gamblin, S.J.3
Codoni, G.4
Macagno, A.5
Jarrossay, D.6
Vachieri, S.G.7
Pinna, D.8
Minola, A.9
Vanzetta, F.10
Silacci, C.11
Fernandez-Rodriguez, B.M.12
Agatic, G.13
Bianchi, S.14
Giacchetto-Sasselli, I.15
Calder, L.16
Sallusto, F.17
Collins, P.18
Haire, L.F.19
Temperton, N.20
Langedijk, J.P.21
Skehel, J.J.22
Lanzavecchia, A.23
more..
-
61
-
-
84888603787
-
Vectored expression of a broadly neutralizing antibody (FI6) in mouse airway provides partial protection against a new avian influenza A (H7N9) virus
-
Limberis MP, Racine T, Kobasa D, Li Y, Gao GF, Kobinger G, Wilson JM. 2013. Vectored expression of a broadly neutralizing antibody (FI6) in mouse airway provides partial protection against a new avian influenza A (H7N9) virus. Clin Vaccine Immunol. 20:1836-1837.
-
(2013)
Clin Vaccine Immunol
, vol.20
, pp. 1836-1837
-
-
Limberis, M.P.1
Racine, T.2
Kobasa, D.3
Li, Y.4
Gao, G.F.5
Kobinger, G.6
Wilson, J.M.7
-
62
-
-
84880296945
-
Broad protection against influenza infection by vectored immunoprophylaxis in mice
-
Balazs AB, Bloom JD, Hong CM, Rao DS, Baltimore D. 2013. Broad protection against influenza infection by vectored immunoprophylaxis in mice. Nat Biotechnol 31:647-652.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 647-652
-
-
Balazs, A.B.1
Bloom, J.D.2
Hong, C.M.3
Rao, D.S.4
Baltimore, D.5
-
63
-
-
62049083943
-
Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses
-
Sui J, Hwang WC, Perez S, Wei G, Aird D, Chen LM, Santelli E, Stec B, Cadwell G, Ali M, Wan H, Murakami A, Yammanuru A, Han T, Cox NJ, Bankston LA, Donis RO, Liddington RC, Marasco WA. 2009. Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses. Nat Struct Mol Biol 16:265-273.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 265-273
-
-
Sui, J.1
Hwang, W.C.2
Perez, S.3
Wei, G.4
Aird, D.5
Chen, L.M.6
Santelli, E.7
Stec, B.8
Cadwell, G.9
Ali, M.10
Wan, H.11
Murakami, A.12
Yammanuru, A.13
Han, T.14
Cox, N.J.15
Bankston, L.A.16
Donis, R.O.17
Liddington, R.C.18
Marasco, W.A.19
-
64
-
-
58049198443
-
Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells
-
Throsby M, van den Brink E, Jongeneelen M, Poon LL, Alard P, Cornelissen L, Bakker A, Cox F, van Deventer E, Guan Y, Cinatl J, Ter Meulen J, Lasters I, Carsetti R, Peiris M, de Kruif J, Goudsmit J. 2008. Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells. PLoS One 3:e3942. doi:10.1371/journal.pone.0003942.
-
(2008)
PLoS One
, vol.3
-
-
Throsby, M.1
van den Brink, E.2
Jongeneelen, M.3
Poon, L.L.4
Alard, P.5
Cornelissen, L.6
Bakker, A.7
Cox, F.8
van Deventer, E.9
Guan, Y.10
Cinatl, J.11
Ter Meulen, J.12
Lasters, I.13
Carsetti, R.14
Peiris, M.15
de Kruif, J.16
Goudsmit, J.17
-
65
-
-
84863186975
-
AAV-directed persistent expression of a gene encoding antinicotine antibody for smoking cessation
-
Hicks MJ, Rosenberg JB, De BP, Pagovich OE, Young CN, Qiu JP, Kaminsky SM, Hackett NR, Worgall S, Janda KD, Davisson RL, Crystal RG. 2012. AAV-directed persistent expression of a gene encoding antinicotine antibody for smoking cessation. Sci Transl Med 4:140ra187. doi:10.1126/scitranslmed.3003611.
-
(2012)
Sci Transl Med
, vol.4
-
-
Hicks, M.J.1
Rosenberg, J.B.2
De, B.P.3
Pagovich, O.E.4
Young, C.N.5
Qiu, J.P.6
Kaminsky, S.M.7
Hackett, N.R.8
Worgall, S.9
Janda, K.D.10
Davisson, R.L.11
Crystal, R.G.12
-
66
-
-
84861664392
-
AAVrh.10-mediated expression of an anti-cocaine antibody mediates persistent passive immunization that suppresses cocaine-induced behavior
-
Rosenberg JB, Hicks MJ, De BP, Pagovich O, Frenk E, Janda KD, Wee S, Koob GF, Hackett NR, Kaminsky SM, Worgall S, Tignor N, Mezey JG, Crystal RG. 2012. AAVrh.10-mediated expression of an anti-cocaine antibody mediates persistent passive immunization that suppresses cocaine-induced behavior. Hum Gene Ther 23:451-459.
-
(2012)
Hum Gene Ther
, vol.23
, pp. 451-459
-
-
Rosenberg, J.B.1
Hicks, M.J.2
De, B.P.3
Pagovich, O.4
Frenk, E.5
Janda, K.D.6
Wee, S.7
Koob, G.F.8
Hackett, N.R.9
Kaminsky, S.M.10
Worgall, S.11
Tignor, N.12
Mezey, J.G.13
Crystal, R.G.14
-
69
-
-
34249289748
-
An antibody delivery system for regulated expression of therapeutic levels of monoclonal antibodies in vivo
-
Fang J, Yi S, Simmons A, Tu GH, Nguyen M, Harding TC, VanRoey M, Jooss K. 2007. An antibody delivery system for regulated expression of therapeutic levels of monoclonal antibodies in vivo. Mol Ther 15:1153-1159.
-
(2007)
Mol Ther
, vol.15
, pp. 1153-1159
-
-
Fang, J.1
Yi, S.2
Simmons, A.3
Tu, G.H.4
Nguyen, M.5
Harding, T.C.6
VanRoey, M.7
Jooss, K.8
-
70
-
-
13544262341
-
Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer
-
Rivera VM, Gao GP, Grant RL, Schnell MA, Zoltick PW, Rozamus LW, Clackson T, Wilson JM. 2005. Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer. Blood 105:1424-1430.
-
(2005)
Blood
, vol.105
, pp. 1424-1430
-
-
Rivera, V.M.1
Gao, G.P.2
Grant, R.L.3
Schnell, M.A.4
Zoltick, P.W.5
Rozamus, L.W.6
Clackson, T.7
Wilson, J.M.8
-
71
-
-
34247208499
-
Rapamycin-regulated control of antiangiogenic tumor therapy following rAAV-mediated gene transfer
-
Nguyen M, Huan-Tu G, Gonzalez-Edick M, Rivera VM, Clackson T, Jooss KU, Harding TC. 2007. Rapamycin-regulated control of antiangiogenic tumor therapy following rAAV-mediated gene transfer. Mol Ther 15:912-920.
-
(2007)
Mol Ther
, vol.15
, pp. 912-920
-
-
Nguyen, M.1
Huan-Tu, G.2
Gonzalez-Edick, M.3
Rivera, V.M.4
Clackson, T.5
Jooss, K.U.6
Harding, T.C.7
-
72
-
-
84898540554
-
Adeno-associated virus delivery of broadly neutralizing antibodies
-
Schnepp BC, Johnson PR. 2014. Adeno-associated virus delivery of broadly neutralizing antibodies. Curr Opin HIV AIDS 9:205-256.
-
(2014)
Curr Opin HIV AIDS
, vol.9
, pp. 205-256
-
-
Schnepp, B.C.1
Johnson, P.R.2
|