메뉴 건너뛰기




Volumn 4, Issue 140, 2012, Pages

AAV-directed persistent expression of a gene encoding anti-nicotine antibody for smoking cessation

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; NICOTINE; NICOTINE ANTIBODY; PARVOVIRUS VECTOR; UNCLASSIFIED DRUG;

EID: 84863186975     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3003611     Document Type: Article
Times cited : (47)

References (46)
  • 1
    • 0347112535 scopus 로고    scopus 로고
    • U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, Atlanta, GA
    • U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Morbidity and Mortality Weekly Report (Centers for Disease Control and Prevention, Atlanta, GA, 2010), pp. 1125-1162.
    • (2010) Morbidity and Mortality Weekly Report , pp. 1125-1162
  • 2
    • 19844373387 scopus 로고    scopus 로고
    • Epidemiology of lung cancer: Looking to the future
    • A. J. Alberg, M. V. Brock, J. M. Samet, Epidemiology of lung cancer: Looking to the future. J. Clin. Oncol. 23, 3175-3185 (2005).
    • (2005) J. Clin. Oncol. , vol.23 , pp. 3175-3185
    • Alberg, A.J.1    Brock, M.V.2    Samet, J.M.3
  • 3
    • 0037083105 scopus 로고    scopus 로고
    • Relation of cigarette smoking to 25-year mortality in middle-aged men with low baseline serum cholesterol: The Chicago Heart Association Detection Project in Industry
    • L. Blanco-Cedres, M. L. Daviglus, D. B. Garside, K. Liu, A. Pirzada, J. Stamler, P. Greenland, Relation of cigarette smoking to 25-year mortality in middle-aged men with low baseline serum cholesterol: The Chicago Heart Association Detection Project in Industry. Am. J. Epidemiol. 155, 354-360 (2002).
    • (2002) Am. J. Epidemiol. , vol.155 , pp. 354-360
    • Blanco-Cedres, L.1    Daviglus, M.L.2    Garside, D.B.3    Liu, K.4    Pirzada, A.5    Stamler, J.6    Greenland, P.7
  • 6
    • 0012843312 scopus 로고    scopus 로고
    • Cigars: Health Effects and Trends
    • National Cancer Institute, National Cancer Institute, Bethesda, MD
    • National Cancer Institute, Smoking and Tobacco Control Monograph 9: Cigars: Health Effects and Trends (National Cancer Institute, Bethesda, MD, 2011).
    • (2011) Smoking and Tobacco Control Monograph , vol.9
  • 7
    • 0022272160 scopus 로고
    • Free-radical chemistry of cigarette smoke and its toxicological implications
    • D. F. Church, W. A. Pryor, Free-radical chemistry of cigarette smoke and its toxicological implications. Environ. Health Perspect. 64, 111-126 (1985).
    • (1985) Environ. Health Perspect. , vol.64 , pp. 111-126
    • Church, D.F.1    Pryor, W.A.2
  • 8
    • 0027247805 scopus 로고
    • Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite
    • W. A. Pryor, K. Stone, Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite. Ann. N. Y. Acad. Sci. 686, 12-27 (1993).
    • (1993) Ann. N. Y. Acad. Sci. , vol.686 , pp. 12-27
    • Pryor, W.A.1    Stone, K.2
  • 9
    • 0032769141 scopus 로고    scopus 로고
    • Arterial nicotine kinetics during cigarette smoking and intravenous nicotine administration: Implications for addiction
    • J. E. Rose, F. M. Behm, E. C. Westman, R. E. Coleman, Arterial nicotine kinetics during cigarette smoking and intravenous nicotine administration: Implications for addiction. Drug Alcohol Depend. 56, 99-107 (1999).
    • (1999) Drug Alcohol Depend. , vol.56 , pp. 99-107
    • Rose, J.E.1    Behm, F.M.2    Westman, E.C.3    Coleman, R.E.4
  • 10
    • 0141746048 scopus 로고    scopus 로고
    • Role of nicotine pharmacokinetics in nicotine addiction and nicotine replacement therapy: A review
    • J. Le Houezec, Role of nicotine pharmacokinetics in nicotine addiction and nicotine replacement therapy: A review. Int. J. Tuberc. Lung Dis. 7, 811-819 (2003).
    • (2003) Int. J. Tuberc. Lung Dis. , vol.7 , pp. 811-819
    • Le Houezec, J.1
  • 11
    • 0021270837 scopus 로고
    • Daily intake of nicotine during cigarette smoking
    • N. L. Benowitz, P. Jacob III, Daily intake of nicotine during cigarette smoking. Clin. Pharmacol. Ther. 35, 499-504 (1984).
    • (1984) Clin. Pharmacol. Ther. , vol.35 , pp. 499-504
    • Benowitz, N.L.1    Jacob III, P.2
  • 12
    • 80052027888 scopus 로고    scopus 로고
    • Recent advances in gene manipulation and nicotinic acetylcholine receptor biology
    • A. Tammimäki, W. J. Horton, J. A. Stitzel, Recent advances in gene manipulation and nicotinic acetylcholine receptor biology. Biochem. Pharmacol. 82, 808-819 (2011).
    • (2011) Biochem. Pharmacol. , vol.82 , pp. 808-819
    • Tammimäki, A.1    Horton, W.J.2    Stitzel, J.A.3
  • 14
    • 65249154248 scopus 로고    scopus 로고
    • Pharmacology of nicotine: Addiction, smoking-induced disease, and therapeutics
    • N. L. Benowitz, Pharmacology of nicotine: Addiction, smoking-induced disease, and therapeutics. Annu. Rev. Pharmacol. Toxicol. 49, 57-71 (2009).
    • (2009) Annu. Rev. Pharmacol. Toxicol. , vol.49 , pp. 57-71
    • Benowitz, N.L.1
  • 17
    • 79952588795 scopus 로고    scopus 로고
    • Treatment of nicotine addiction: Present therapeutic options and pipeline developments
    • R. Polosa, N. L. Benowitz, Treatment of nicotine addiction: Present therapeutic options and pipeline developments. Trends Pharmacol. Sci. 32, 281-289 (2011).
    • (2011) Trends Pharmacol. Sci. , vol.32 , pp. 281-289
    • Polosa, R.1    Benowitz, N.L.2
  • 19
    • 80052549139 scopus 로고    scopus 로고
    • Risk of serious adverse cardiovascular events associated with varenicline: A systematic review and meta-analysis
    • S. Singh, Y. K. Loke, J. G. Spangler, C. D. Furberg, Risk of serious adverse cardiovascular events associated with varenicline: A systematic review and meta-analysis. CMAJ 183, 1359-1366 (2011).
    • (2011) CMAJ , vol.183 , pp. 1359-1366
    • Singh, S.1    Loke, Y.K.2    Spangler, J.G.3    Furberg, C.D.4
  • 20
    • 33644801063 scopus 로고    scopus 로고
    • Current status of immunologic approaches to treating tobacco dependence: Vaccines and nicotine-specific antibodies
    • M. G. LeSage, D. E. Keyler, P. R. Pentel, Current status of immunologic approaches to treating tobacco dependence: Vaccines and nicotine-specific antibodies. AAPS J. 8, E65-E75 (2006).
    • (2006) AAPS J. , vol.8
    • LeSage, M.G.1    Keyler, D.E.2    Pentel, P.R.3
  • 21
    • 58149348655 scopus 로고    scopus 로고
    • Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: Evidence from genetically modified mice
    • C. D. Fowler, M. A. Arends, P. J. Kenny, Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: Evidence from genetically modified mice. Behav. Pharmacol. 19, 461-484 (2008).
    • (2008) Behav. Pharmacol. , vol.19 , pp. 461-484
    • Fowler, C.D.1    Arends, M.A.2    Kenny, P.J.3
  • 23
    • 0035874752 scopus 로고    scopus 로고
    • An immunotherapeutic program for the treatment of nicotine addiction: Hapten design and synthesis
    • S. Isomura, P. Wirsching, K. D. Janda, An immunotherapeutic program for the treatment of nicotine addiction: Hapten design and synthesis. J. Org. Chem. 66, 4115-4121 (2001).
    • (2001) J. Org. Chem. , vol.66 , pp. 4115-4121
    • Isomura, S.1    Wirsching, P.2    Janda, K.D.3
  • 25
    • 28844483864 scopus 로고    scopus 로고
    • High levels of persistent expression of a1-antitrypsin mediated by the nonhuman primate serotype rh.10 adeno-associated virus despite preexisting immunity to common human adeno-associated viruses
    • B. P. De, A. Heguy, N. R. Hackett, B. Ferris, P. L. Leopold, J. Lee, L. Pierre, G. Gao, J. M. Wilson, R. G. Crystal, High levels of persistent expression of a1-antitrypsin mediated by the nonhuman primate serotype rh.10 adeno-associated virus despite preexisting immunity to common human adeno-associated viruses. Mol. Ther. 13, 67-76 (2006).
    • (2006) Mol. Ther. , vol.13 , pp. 67-76
    • De, B.P.1    Heguy, A.2    Hackett, N.R.3    Ferris, B.4    Leopold, P.L.5    Lee, J.6    Pierre, L.7    Gao, G.8    Wilson, J.M.9    Crystal, R.G.10
  • 26
    • 0018068378 scopus 로고
    • Cigarette smoking: A dependence on high-nicotine boli
    • M. A. Russell, C. Feyerabend, Cigarette smoking: A dependence on high-nicotine boli. Drug Metab. Rev. 8, 29-57 (1978).
    • (1978) Drug Metab. Rev. , vol.8 , pp. 29-57
    • Russell, M.A.1    Feyerabend, C.2
  • 27
    • 33847109839 scopus 로고    scopus 로고
    • Characterization and comparison of nicotine and cotinine metabolism in vitro and in vivo in DBA/2 and C57BL/6 mice
    • E. C. Siu, R. F. Tyndale, Characterization and comparison of nicotine and cotinine metabolism in vitro and in vivo in DBA/2 and C57BL/6 mice. Mol. Pharmacol. 71, 826-834 (2007).
    • (2007) Mol. Pharmacol. , vol.71 , pp. 826-834
    • Siu, E.C.1    Tyndale, R.F.2
  • 28
    • 59649092315 scopus 로고    scopus 로고
    • Immunopharmacotherapy: Vaccination strategies as a treatment for drug abuse and dependence
    • A. Y. Moreno, K. D. Janda, Immunopharmacotherapy: Vaccination strategies as a treatment for drug abuse and dependence. Pharmacol. Biochem. Behav. 92, 199-205 (2009).
    • (2009) Pharmacol. Biochem. Behav. , vol.92 , pp. 199-205
    • Moreno, A.Y.1    Janda, K.D.2
  • 30
    • 77950589619 scopus 로고    scopus 로고
    • A critical evaluation of a nicotine vaccine within a self-administration behavioral model
    • A. Y. Moreno, M. R. Azar, N. A. Warren, T. J. Dickerson, G. F. Koob, K. D. Janda, A critical evaluation of a nicotine vaccine within a self-administration behavioral model. Mol. Pharm. 7, 431-441 (2010).
    • (2010) Mol. Pharm. , vol.7 , pp. 431-441
    • Moreno, A.Y.1    Azar, M.R.2    Warren, N.A.3    Dickerson, T.J.4    Koob, G.F.5    Janda, K.D.6
  • 32
    • 36049039339 scopus 로고    scopus 로고
    • Vaccination against nicotine: An emerging therapy for tobacco dependence
    • P. Maurer, M. F. Bachmann, Vaccination against nicotine: An emerging therapy for tobacco dependence. Expert Opin. Investig. Drugs 16, 1775-1783 (2007).
    • (2007) Expert Opin. Investig. Drugs , vol.16 , pp. 1775-1783
    • Maurer, P.1    Bachmann, M.F.2
  • 33
    • 84863193034 scopus 로고    scopus 로고
    • Antismoking vaccine fails in late trial
    • 18 July
    • A. Pollack, Antismoking vaccine fails in late trial, New York Times, 18 July 2011.
    • (2011) New York Times
    • Pollack, A.1
  • 34
    • 0033859862 scopus 로고    scopus 로고
    • Vaccination against nicotine during continued nicotine administration in rats: Immunogenicity of the vaccine and effects on nicotine distribution to brain
    • Y. Hieda, D. E. Keyler, S. Ennifar, A. Fattom, P. R. Pentel, Vaccination against nicotine during continued nicotine administration in rats: Immunogenicity of the vaccine and effects on nicotine distribution to brain. Int. J. Immunopharmacol. 22, 809-819 (2000).
    • (2000) Int. J. Immunopharmacol. , vol.22 , pp. 809-819
    • Hieda, Y.1    Keyler, D.E.2    Ennifar, S.3    Fattom, A.4    Pentel, P.R.5
  • 36
    • 0023837297 scopus 로고
    • Smoking and mechanisms of cardiovascular control
    • D. Robertson, C. J. Tseng, M. Appalsamy, Smoking and mechanisms of cardiovascular control. Am. Heart J. 115, 258-263 (1988).
    • (1988) Am. Heart J. , vol.115 , pp. 258-263
    • Robertson, D.1    Tseng, C.J.2    Appalsamy, M.3
  • 37
    • 0037137158 scopus 로고    scopus 로고
    • Acute ventilatory and circulatory reactions evoked by nicotine: Are they excitatory or depressant?
    • R. Fernández, C. Larraín, P. Zapata, Acute ventilatory and circulatory reactions evoked by nicotine: Are they excitatory or depressant? Respir. Physiol. Neurobiol. 133, 173-182 (2002).
    • (2002) Respir. Physiol. Neurobiol. , vol.133 , pp. 173-182
    • Fernández, R.1    Larraín, C.2    Zapata, P.3
  • 38
    • 0014074452 scopus 로고
    • Effects of nicotine on heart rate studied by direct perfusion of sinus code
    • R. A. Nadeau, T. N. James, Effects of nicotine on heart rate studied by direct perfusion of sinus code. Am. J. Physiol. 212, 911-916 (1967).
    • (1967) Am. J. Physiol. , vol.212 , pp. 911-916
    • Nadeau, R.A.1    James, T.N.2
  • 39
    • 78650274939 scopus 로고    scopus 로고
    • Individual differences in prefrontal cortex function and the transition from drug use to drug dependence
    • O. George, G. F. Koob, Individual differences in prefrontal cortex function and the transition from drug use to drug dependence. Neurosci. Biobehav. Rev. 35, 232-247 (2010).
    • (2010) Neurosci. Biobehav. Rev. , vol.35 , pp. 232-247
    • George, O.1    Koob, G.F.2
  • 42
    • 0025884056 scopus 로고
    • Efficient selection for high-expression transfectants with a novel eukaryotic vector
    • H. Niwa, K. Yamamura, J. Miyazaki, Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108, 193-199 (1991).
    • (1991) Gene , vol.108 , pp. 193-199
    • Niwa, H.1    Yamamura, K.2    Miyazaki, J.3
  • 43
    • 2642642141 scopus 로고    scopus 로고
    • Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus
    • X. Xiao, J. Li, R. J. Samulski, Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus. J. Virol. 72, 2224-2232 (1998).
    • (1998) J. Virol. , vol.72 , pp. 2224-2232
    • Xiao, X.1    Li, J.2    Samulski, R.J.3
  • 44
    • 0020971366 scopus 로고
    • Determination of affinity and specificity of anti-hapten antibodies by competitive radioimmunoassay
    • R. Müller, Determination of affinity and specificity of anti-hapten antibodies by competitive radioimmunoassay. Methods Enzymol. 92, 589-601 (1983).
    • (1983) Methods Enzymol. , vol.92 , pp. 589-601
    • Müller, R.1
  • 45
    • 0347671203 scopus 로고    scopus 로고
    • Long-term telemetric measurement of cardiovascular parameters in awake mice: A physiological genomics tool
    • G. M. Butz, R. L. Davisson, Long-term telemetric measurement of cardiovascular parameters in awake mice: A physiological genomics tool. Physiol. Genomics 5, 89-97 (2001).
    • (2001) Physiol. Genomics , vol.5 , pp. 89-97
    • Butz, G.M.1    Davisson, R.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.