A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation

Science

Volumn 351, Issue 6272, 2016, Pages

  Kaufman, Charles K ^a,b,c,d   Mosimann, Christian ^e   Fan, Zi Peng ^f,g   Yang, Song ^a,b   Thomas, Andrew J ^a   Ablain, Julien ^a,b,d   Tan, Justin L ^a   Fogley, Rachel D ^a   Van Rooijen, Ellen ^a,b,d   Hagedorn, Elliott J ^a,b,d   Ciarlo, Christie ^a,d   White, Richard M ^h   Matos, Dominick A ^d   Puller, Ann Christin ⁱ   Santoriello, Cristina ^a,j   Liao, Eric C ^b,d,k   Young, Richard A ^f,g   Zon, Leonard I ^a,b,c,d,j  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b HARVARD STEM CELL INSTITUTE   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e UNIVERSITY OF ZURICH   (Switzerland)

^f WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^g MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^h MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

ⁱ UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^j Harvard University   (United States)

^k MASSACHUSETTS GENERAL HOSPITAL   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; ENHANCED GREEN FLUORESCENT PROTEIN; PROTEIN P53; TRANSCRIPTION FACTOR SOX10; BRAF PROTEIN, HUMAN; CRESTIN PROTEIN, ZEBRAFISH; GREEN FLUORESCENT PROTEIN; NERVE PROTEIN; SOX10 PROTEIN, ZEBRAFISH; TRANSCRIPTION FACTOR SOX; ZEBRAFISH PROTEIN;

CANCER; CARCINOGEN; CELLS AND CELL COMPONENTS; CYPRINID; GENE EXPRESSION; GENETIC ANALYSIS; MODELING; MUTATION; TUMOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL EXPANSION; CELL MIGRATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DISEASE COURSE; EMBRYO CELL; ENHANCER REGION; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; LOSS OF FUNCTION MUTATION; MELANOMA; MELANOMA CELL; NEURAL CREST; NEURAL CREST CELL; NONHUMAN; OLIGODENDROGLIA; OPEN READING FRAME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REPORTER GENE; TRANSGENIC ZEBRAFISH; TRANSGENICS; ANIMAL; CARCINOGENESIS; EMBRYONIC STEM CELL; EXPERIMENTAL MELANOMA; GENE EXPRESSION REGULATION; GENETICS; MELANOCYTE; METABOLISM; MUTATION; SKIN TUMOR; TRANSGENIC ANIMAL; ZEBRA FISH;

DANIO RERIO;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CARCINOGENESIS; EMBRYONIC STEM CELLS; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; MELANOCYTES; MELANOMA; MELANOMA, EXPERIMENTAL; MUTATION; NERVE TISSUE PROTEINS; NEURAL CREST; PROTO-ONCOGENE PROTEINS B-RAF; SKIN NEOPLASMS; SOXE TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84958729616     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aad2197     Document Type: Article

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