The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models

Genome Biology

Volumn 14, Issue 10, 2013, Pages

  Yen, Jennifer ^a   White, Richard M ^b   Wedge, David C ^a   Van Loo, Peter ^a,c   de Ridder, Jeroen ^d   Capper, Amy ^e   Richardson, Jennifer ^e   Jones, David ^a   Raine, Keiran ^a   Watson, Ian R ^f   Wu, Chang Jiun ^f   Cheng, Jiqiu ^g   Martincorena, Iñigo ^a   Nik Zainal, Serena ^a   Mudie, Laura ^a   Moreau, Yves ^g   Marshall, John ^a   Ramakrishna, Manasa ^a   Tarpey, Patrick ^a   Shlien, Adam ^a   Whitmore, Ian ^a   Gamble, Steve ^a   Latimer, Calli ^a   Langdon, Erin ^h   Kaufman, Charles ^h   Dovey, Mike ^h   Taylor, Alison ^h   Menzies, Andy ^a   McLaren, Stuart ^a   O'Meara, Sarah ^a   Butler, Adam ^a   Teague, Jon ^a   Lister, James ⁱ   Chin, Lynda ^f   Campbell, Peter ^a   Adams, David J ^a   Zon, Leonard I ^h   Patton, E E ^e   Stemple, Derek L ^a   Futreal, P A ^a,f   more..

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

^f UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^g Katholieke Universiteit Leuven   (Belgium)

^h BOSTON CHILDREN S HOSPITAL   (United States)

ⁱ VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUTAMIC ACID; GLUTAMINE; LYSINE; MITOGEN ACTIVATED PROTEIN KINASE; VALINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOENGINEERING; BRAF GENE; CANCER GENETICS; CANCER MODEL; CARCINOGENESIS; CONTROLLED STUDY; GENE; GENE AMPLIFICATION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GERM LINE; MELANOGENESIS; MELANOMA; MUTATIONAL ANALYSIS; NONHUMAN; NRAS GENE; RADIATION EXPOSURE; SIGNAL TRANSDUCTION; TRANSGENIC ANIMAL; TUMOR SUPPRESSOR GENE; ULTRAVIOLET RADIATION; ZEBRA FISH; ANIMAL; COPY NUMBER VARIATION; DISEASE MODEL; GENE DELETION; GENE INACTIVATION; GENETICS; HOMOZYGOTE; INDEL MUTATION; MUTATION; PATHOLOGY; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

DANIO RERIO;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; DISEASE MODELS, ANIMAL; DNA COPY NUMBER VARIATIONS; GENE AMPLIFICATION; GENE KNOCKOUT TECHNIQUES; GENETIC HETEROGENEITY; HOMOZYGOTE; INDEL MUTATION; MELANOMA; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SEQUENCE DELETION; ULTRAVIOLET RAYS; ZEBRAFISH;

EID: 84886228663     PISSN: None     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/gb-2013-14-10-r113     Document Type: Article

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